Interneuron odyssey: molecular mechanisms of tangential migration.
GABA
blood vessels
cytoskeleton
interneurons
migration
neurodevelopmental disorders
oligodendrocytes
therapy
Journal
Frontiers in neural circuits
ISSN: 1662-5110
Titre abrégé: Front Neural Circuits
Pays: Switzerland
ID NLM: 101477940
Informations de publication
Date de publication:
2023
2023
Historique:
received:
10
07
2023
accepted:
21
08
2023
medline:
3
10
2023
pubmed:
2
10
2023
entrez:
2
10
2023
Statut:
epublish
Résumé
Cortical GABAergic interneurons are critical components of neural networks. They provide local and long-range inhibition and help coordinate network activities involved in various brain functions, including signal processing, learning, memory and adaptative responses. Disruption of cortical GABAergic interneuron migration thus induces profound deficits in neural network organization and function, and results in a variety of neurodevelopmental and neuropsychiatric disorders including epilepsy, intellectual disability, autism spectrum disorders and schizophrenia. It is thus of paramount importance to elucidate the specific mechanisms that govern the migration of interneurons to clarify some of the underlying disease mechanisms. GABAergic interneurons destined to populate the cortex arise from multipotent ventral progenitor cells located in the ganglionic eminences and pre-optic area. Post-mitotic interneurons exit their place of origin in the ventral forebrain and migrate dorsally using defined migratory streams to reach the cortical plate, which they enter through radial migration before dispersing to settle in their final laminar allocation. While migrating, cortical interneurons constantly change their morphology through the dynamic remodeling of actomyosin and microtubule cytoskeleton as they detect and integrate extracellular guidance cues generated by neuronal and non-neuronal sources distributed along their migratory routes. These processes ensure proper distribution of GABAergic interneurons across cortical areas and lamina, supporting the development of adequate network connectivity and brain function. This short review summarizes current knowledge on the cellular and molecular mechanisms controlling cortical GABAergic interneuron migration, with a focus on tangential migration, and addresses potential avenues for cell-based interneuron progenitor transplants in the treatment of neurodevelopmental disorders and epilepsy.
Identifiants
pubmed: 37779671
doi: 10.3389/fncir.2023.1256455
pmc: PMC10538647
doi:
Types de publication
Journal Article
Review
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1256455Subventions
Organisme : CIHR
ID : PJT-173284
Pays : Canada
Informations de copyright
Copyright © 2023 Toudji, Toumi, Chamberland and Rossignol.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Front Mol Neurosci. 2019 Apr 12;12:85
pubmed: 31031591
J Biol Chem. 2001 Aug 10;276(32):29628-31
pubmed: 11390369
Nat Neurosci. 2013 Jun;16(6):692-7
pubmed: 23644485
Hum Mol Genet. 2014 Sep 15;23(18):4846-58
pubmed: 24781210
Brain Res. 2018 Dec 1;1700:160-169
pubmed: 30194015
Neuron. 1999 Jul;23(3):473-85
pubmed: 10433260
Am J Hum Genet. 2009 Apr;84(4):524-33
pubmed: 19344873
Am J Hum Genet. 2020 Mar 5;106(3):338-355
pubmed: 32109419
Cell Transplant. 2010;19(5):549-64
pubmed: 20144261
Front Mol Neurosci. 2019 Apr 02;12:75
pubmed: 31001083
Cells. 2022 Feb 09;11(4):
pubmed: 35203254
J Neuropathol Exp Neurol. 2011 Oct;70(10):841-58
pubmed: 21937910
J Neurosci. 2014 Jul 16;34(29):9506-15
pubmed: 25031394
J Neurosci. 2006 Jul 12;26(28):7380-9
pubmed: 16837585
Neuron. 2009 Apr 16;62(1):53-71
pubmed: 19376067
Eur J Neurosci. 2008 Jul;28(1):62-73
pubmed: 18662335
Essays Biochem. 2019 Oct 31;63(5):509-520
pubmed: 31358621
Cereb Cortex. 2017 Jan 1;27(1):793-808
pubmed: 26620267
Cell Adh Migr. 2008 Jul-Sep;2(3):167-9
pubmed: 19262109
World J Clin Cases. 2020 Nov 6;8(21):5296-5303
pubmed: 33269262
Clin Dysmorphol. 2017 Jan;26(1):38-40
pubmed: 27753653
Development. 2004 Apr;131(7):1503-13
pubmed: 14998923
Elife. 2021 Apr 27;10:
pubmed: 33904394
Curr Opin Neurobiol. 2017 Feb;42:17-24
pubmed: 27889625
Histol Histopathol. 2014 Jul;29(7):871-9
pubmed: 24523202
Cereb Cortex. 2015 Sep;25(9):2370-82
pubmed: 24626607
Dev Biol. 2003 Oct 15;262(2):225-41
pubmed: 14550787
Proc Natl Acad Sci U S A. 2016 Feb 23;113(8):2264-9
pubmed: 26858404
J Neurosci. 2010 Jun 23;30(25):8660-70
pubmed: 20573911
Sci Signal. 2018 Apr 10;11(525):
pubmed: 29636391
J Neurosci. 2013 Sep 11;33(37):14809-15
pubmed: 24027281
Nat Neurosci. 2020 Apr;23(4):520-532
pubmed: 32123378
Cereb Cortex. 2011 Aug;21(8):1771-82
pubmed: 21139075
Cereb Cortex. 2019 Jun 1;29(6):2653-2667
pubmed: 29878134
Dev Cell. 2012 Oct 16;23(4):729-44
pubmed: 23022035
J Comp Neurol. 2013 May 1;521(7):1561-84
pubmed: 23042297
Brain Res. 2015 May 22;1608:82-90
pubmed: 25727174
J Neurosci. 2003 Jun 15;23(12):5123-30
pubmed: 12832536
J Cell Commun Signal. 2009 Dec;3(3-4):255-73
pubmed: 19809893
Nat Neurosci. 2018 Jul;21(7):920-931
pubmed: 29915195
Am J Hum Genet. 2014 Jun 5;94(6):891-7
pubmed: 24814191
Front Psychiatry. 2022 Oct 12;13:913550
pubmed: 36311505
Nat Neurosci. 2013 Nov;16(11):1588-97
pubmed: 24097041
FEBS Lett. 2003 Mar 27;539(1-3):131-7
pubmed: 12650940
Annu Rev Genomics Hum Genet. 2016 Aug 31;17:17-43
pubmed: 27089971
Neuron. 2013 Jan 9;77(1):83-98
pubmed: 23312518
J Alzheimers Dis. 2020;75(1):245-260
pubmed: 32280096
Mol Psychiatry. 2019 Sep;24(9):1329-1350
pubmed: 29467497
Mol Cell Neurosci. 2011 Dec;48(4):349-58
pubmed: 21722732
Neural Plast. 2011;2011:649325
pubmed: 21876820
Cell Res. 2016 Oct;26(10):1131-1148
pubmed: 27670698
J Neurosci. 2006 Dec 20;26(51):13273-8
pubmed: 17182777
Science. 2001 Aug 3;293(5531):872-5
pubmed: 11486090
Nat Neurosci. 1999 May;2(5):461-6
pubmed: 10321251
Nature. 2009 May 28;459(7246):596-600
pubmed: 19387438
Nat Commun. 2021 May 11;12(1):2678
pubmed: 33976153
Cell Adh Migr. 2010 Jul-Sep;4(3):400-8
pubmed: 20473036
Nat Rev Neurosci. 2006 Sep;7(9):687-96
pubmed: 16883309
Sci Rep. 2020 May 12;10(1):7834
pubmed: 32398858
Eur J Neurosci. 2011 Nov;34(10):1584-94
pubmed: 22103416
Sci Signal. 2017 Jul 11;10(487):
pubmed: 28698213
Schizophr Bull. 2021 Apr 29;47(3):812-826
pubmed: 33067994
Nat Neurosci. 2006 Feb;9(2):173-9
pubmed: 16388308
J Neurosci. 2015 Sep 16;35(37):12869-89
pubmed: 26377473
Mol Psychiatry. 2019 Sep;24(9):1248-1257
pubmed: 31089192
PLoS One. 2007 Aug 29;2(8):e794
pubmed: 17726524
Cereb Cortex. 2011 Apr;21(4):845-52
pubmed: 20732898
Nat Rev Neurosci. 2012 Jan 18;13(2):107-20
pubmed: 22251963
Mol Cell. 2007 May 11;26(3):437-48
pubmed: 17499049
J Neurosci. 2010 Apr 14;30(15):5334-45
pubmed: 20392955
Front Cell Neurosci. 2022 Jul 05;16:939294
pubmed: 35865112
Nature. 2002 Dec 12;420(6916):629-35
pubmed: 12478284
Small GTPases. 2014;5:e29769
pubmed: 24987837
J Cereb Blood Flow Metab. 2009 Jun;29(6):1146-58
pubmed: 19367295
Nat Cell Biol. 1999 Jul;1(3):136-43
pubmed: 10559899
Development. 2006 Jun;133(11):2243-52
pubmed: 16690755
Nature. 2020 Oct;586(7828):262-269
pubmed: 32999462
J Med Genet. 2016 Nov;53(11):735-742
pubmed: 27418539
EMBO J. 2003 Aug 15;22(16):4190-201
pubmed: 12912917
Neuron. 2004 Oct 14;44(2):251-61
pubmed: 15473965
Neuron. 2012 Mar 8;73(5):903-10
pubmed: 22405201
Int J Neuropsychopharmacol. 2013 Apr;16(3):549-56
pubmed: 22831755
Dev Biol. 1999 Aug 15;212(2):290-306
pubmed: 10433822
Cereb Cortex. 2003 Mar;13(3):252-64
pubmed: 12571115
Gene. 2022 Apr 20;819:146206
pubmed: 35092861
Science. 2016 Jan 22;351(6271):379-84
pubmed: 26798014
J Cell Biol. 2017 Dec 4;216(12):4313-4330
pubmed: 29089377
Development. 2007 May;134(9):1755-65
pubmed: 17409112
Trends Cell Biol. 2004 Aug;14(8):461-9
pubmed: 15308213
Neuron. 2005 Mar 3;45(5):701-13
pubmed: 15748846
Nat Rev Mol Cell Biol. 2007 Jan;8(1):37-48
pubmed: 17183359
J Neurosci. 2011 Apr 20;31(16):6174-87
pubmed: 21508241
Dev Neurobiol. 2011 Sep;71(9):747-58
pubmed: 21557512
J Biol Chem. 2016 May 27;291(22):11466-75
pubmed: 27026702
J Neurosci. 2008 Jan 30;28(5):1085-98
pubmed: 18234887
Genes Dev. 2002 Oct 15;16(20):2684-98
pubmed: 12381667
Neuroscience. 2019 Feb 10;399:199-210
pubmed: 30594563
Science. 2005 Jun 17;308(5729):1758-62
pubmed: 15890843
Exp Cell Res. 2013 Sep 10;319(15):2368-74
pubmed: 23769912
eNeuro. 2020 Aug 20;7(4):
pubmed: 32737185
Neuron. 2016 Sep 21;91(6):1260-1275
pubmed: 27657450
Eur J Hum Genet. 2001 Jan;9(1):5-12
pubmed: 11175293
Front Neurosci. 2023 Mar 02;17:1123784
pubmed: 36937657
J Cell Sci. 2023 Mar 15;136(6):
pubmed: 36744839
J Cell Biol. 2012 May 14;197(4):465-75
pubmed: 22584905
Nat Commun. 2021 Jun 18;12(1):3773
pubmed: 34145239
Front Cell Neurosci. 2015 Jan 30;9:4
pubmed: 25688185
PLoS Genet. 2014 Jun 05;10(6):e1004345
pubmed: 24901509
Nature. 1998 Jun 25;393(6687):805-9
pubmed: 9655397
Cereb Cortex. 2018 Nov 1;28(11):3797-3815
pubmed: 29028947
Cell Stem Cell. 2022 Feb 3;29(2):248-264.e7
pubmed: 34990580
Curr Opin Neurobiol. 2013 Dec;23(6):951-6
pubmed: 23973156
Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):287-296
pubmed: 30559206
J Neurosci. 2017 Sep 6;37(36):8816-8829
pubmed: 28821666
Mol Psychiatry. 2021 Nov;26(11):6845-6867
pubmed: 33863995
Nat Neurosci. 2008 Apr;11(4):429-39
pubmed: 18344991
Neuron. 2013 Sep 18;79(6):1152-68
pubmed: 24050403
Cells. 2021 Oct 01;10(10):
pubmed: 34685590
Curr Biol. 2014 Aug 4;24(15):1778-85
pubmed: 25065758
Nat Neurosci. 2012 Jan 15;15(3):373-80, S1-2
pubmed: 22246438
Trends Neurosci. 2010 Aug;33(8):362-72
pubmed: 20541813
Curr Biol. 2014 Mar 3;24(5):494-508
pubmed: 24560577
Cell. 2009 Feb 6;136(3):551-64
pubmed: 19185337
Am J Hum Genet. 2018 Oct 4;103(4):579-591
pubmed: 30290153
Elife. 2023 Apr 04;12:
pubmed: 37014118
Development. 2003 May;130(9):1889-901
pubmed: 12642493
Neuron. 2013 Jan 9;77(1):70-82
pubmed: 23312517
Science. 1997 Oct 17;278(5337):474-6
pubmed: 9334308
Nature. 2011 Apr 21;472(7343):351-5
pubmed: 21460837
J Neurosci. 2010 Feb 3;30(5):1582-94
pubmed: 20130169
Development. 2009 Jan;136(1):41-50
pubmed: 19060332
Sci Rep. 2016 Feb 03;6:20282
pubmed: 26838264
Front Cell Neurosci. 2015 Jan 07;8:445
pubmed: 25610373
Nat Commun. 2017 Sep 19;8(1):601
pubmed: 28928363
Dev Biol. 2014 Nov 1;395(1):4-18
pubmed: 25224226
Curr Biol. 2003 Apr 1;13(7):534-45
pubmed: 12676083
Science. 1999 Mar 26;283(5410):2083-5
pubmed: 10092231
Development. 2014 Jan;141(2):460-71
pubmed: 24381199
Am J Hum Genet. 2013 Jul 11;93(1):124-31
pubmed: 23746550
Nat Rev Mol Cell Biol. 2020 Jun;21(6):307-326
pubmed: 32107477
Neurosci Bull. 2022 Mar;38(3):249-262
pubmed: 34914033
Int J Mol Sci. 2019 Aug 26;20(17):
pubmed: 31454984
Eur J Hum Genet. 2021 Sep;29(9):1377-1383
pubmed: 33603162
Cereb Cortex. 2018 Jul 1;28(7):2577-2593
pubmed: 29901792
Hum Mol Genet. 2016 Mar 1;25(5):892-902
pubmed: 26721934
eNeuro. 2022 Jan 28;9(1):
pubmed: 34930830
Development. 2002 Jul;129(13):3147-60
pubmed: 12070090
Cereb Cortex. 2010 Dec;20(12):2810-7
pubmed: 20200107
Development. 2017 Nov 1;144(21):3867-3878
pubmed: 29089360
Science. 2020 Jun 12;368(6496):1205-1210
pubmed: 32527825
Science. 2004 Mar 26;303(5666):2007-10
pubmed: 15044801
Neuron. 2019 Jun 5;102(5):960-975.e6
pubmed: 31027966
Nat Rev Neurosci. 2014 May;15(5):285-99
pubmed: 24739785
Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5861-6
pubmed: 21422296
Ann Neurol. 2013 Aug;74(2):209-22
pubmed: 23595603
Nature. 2010 Jan 28;463(7280):554-8
pubmed: 20054296
Mol Psychiatry. 2023 Apr;28(4):1527-1544
pubmed: 36717740
Development. 2001 Oct;128(19):3759-71
pubmed: 11585802
Cereb Cortex. 2011 Aug;21(8):1792-802
pubmed: 21148088
Thromb Haemost. 2004 Mar;91(3):595-605
pubmed: 14983237
EMBO J. 2014 Mar 3;33(5):501-11
pubmed: 24502975
Cereb Cortex. 2017 Dec 1;27(12):5525-5538
pubmed: 27756764
Nat Neurosci. 2011 Dec 11;15(2):267-73
pubmed: 22158511
BMC Med Genet. 2017 Jun 15;18(1):68
pubmed: 28619046
J Neurosci. 2019 Jan 2;39(1):177-192
pubmed: 30377227
Cell Mol Life Sci. 2020 May;77(10):1959-1986
pubmed: 31392351
J Neurosci. 2011 Feb 2;31(5):1739-45
pubmed: 21289183
Nat Neurosci. 2011 Dec 11;15(2):258-66
pubmed: 22158510
Nat Rev Mol Cell Biol. 2005 Feb;6(2):167-80
pubmed: 15688002
Mol Neuropsychiatry. 2016 Jul;2(2):79-87
pubmed: 27606322
J Biol Chem. 2008 Feb 15;283(7):3915-22
pubmed: 18045879
Mol Cell Proteomics. 2013 Aug;12(8):2096-110
pubmed: 23620545
Prog Brain Res. 2016;226:81-126
pubmed: 27323940
Neuron. 2007 Jun 21;54(6):873-88
pubmed: 17582329
Exp Cell Res. 2003 Mar 10;284(1):14-30
pubmed: 12648463
J Neurosci. 2008 Feb 13;28(7):1613-24
pubmed: 18272682
Front Mol Neurosci. 2022 Mar 16;15:826427
pubmed: 35370549
Elife. 2016 Dec 09;5:
pubmed: 27935475
Front Cell Neurosci. 2015 Apr 14;9:129
pubmed: 25926769
Cancer Res. 2017 Mar 15;77(6):1427-1438
pubmed: 28108508
Development. 2020 Jan 17;147(2):
pubmed: 31915148
J Cell Biol. 2004 Jun 7;165(5):709-21
pubmed: 15173193
Front Neurosci. 2023 Apr 14;17:1177678
pubmed: 37123353
Dev Cell. 2016 Mar 21;36(6):624-38
pubmed: 27003936
Cereb Cortex. 2014 May;24(5):1247-58
pubmed: 23258346
J Neurosci. 2012 Apr 25;32(17):6032-42
pubmed: 22539863
J Mol Biol. 2007 May 18;368(5):1307-20
pubmed: 17391702
Cell Rep. 2016 Aug 2;16(5):1431-1444
pubmed: 27452460
J Neurosci. 1999 Sep 15;19(18):7881-8
pubmed: 10479690
Cell Rep. 2013 Feb 21;3(2):291-300
pubmed: 23403289
Neurobiol Dis. 2022 Jun 15;168:105713
pubmed: 35346832
Cell Rep. 2017 Jan 31;18(5):1157-1170
pubmed: 28147272
Development. 2013 Aug;140(15):3139-45
pubmed: 23861058
J Neurosci. 2023 Feb 22;43(8):1422-1440
pubmed: 36717229
J Comp Neurol. 2019 Dec 1;527(17):2860-2874
pubmed: 31070778
Cell Rep. 2022 Aug 2;40(5):111157
pubmed: 35926459
J Neurosci. 2014 Apr 2;34(14):4941-62
pubmed: 24695713
Nat Genet. 2011 Jun;43(6):585-9
pubmed: 21572417
J Cell Sci. 2004 Sep 1;117(Pt 19):4343-54
pubmed: 15331659
J Neurosci. 2014 Jun 4;34(23):7787-801
pubmed: 24899703
Mol Psychiatry. 2021 Dec;26(12):7621-7640
pubmed: 33963279
Epilepsia. 2014 Aug;55(8):1292-300
pubmed: 24836831
Nat Rev Mol Cell Biol. 2016 Aug;17(8):496-510
pubmed: 27301673
Sci Rep. 2017 Mar 09;7:42895
pubmed: 28276447
Neuron. 2009 Aug 27;63(4):466-81
pubmed: 19709629
Cereb Cortex. 2018 Nov 1;28(11):3868-3879
pubmed: 29028946
Cereb Cortex. 2003 Sep;13(9):932-42
pubmed: 12902392
J Biol Chem. 2001 Aug 31;276(35):32743-9
pubmed: 11435442
Eur J Med Genet. 2017 Apr;60(4):212-216
pubmed: 28126652
Front Neurol. 2021 Apr 09;12:643964
pubmed: 33897599
EMBO J. 2011 Jun 14;30(14):2920-33
pubmed: 21673655
Am J Pathol. 2004 Sep;165(3):775-84
pubmed: 15331402
J Neurosci. 2015 Jun 10;35(23):8718-29
pubmed: 26063906
J Neurosci. 2010 Dec 15;30(50):16796-808
pubmed: 21159951
Nat Neurosci. 2021 Dec;24(12):1745-1756
pubmed: 34737447
Proc Natl Acad Sci U S A. 2000 Oct 24;97(22):12074-8
pubmed: 11050238
Cell. 2020 Jan 23;180(2):323-339.e19
pubmed: 31928845
J Neurosci. 2020 Mar 25;40(13):2764-2775
pubmed: 32102923
Front Cell Dev Biol. 2022 Dec 08;10:875468
pubmed: 36568982
J Biol Chem. 2013 Jul 19;288(29):21117-21125
pubmed: 23760270
Neuron. 2001 Apr;30(1):79-89
pubmed: 11343646
Genes Dev. 2005 Jan 1;19(1):1-49
pubmed: 15630019
J Neurosci. 2015 Aug 05;35(31):10977-88
pubmed: 26245961
Nat Rev Mol Cell Biol. 2013 Nov;14(11):713-26
pubmed: 24064538
Neurotherapeutics. 2011 Oct;8(4):763-73
pubmed: 21748528
Nat Commun. 2013;4:2149
pubmed: 23857367
Cell. 2007 Jun 1;129(5):865-77
pubmed: 17540168
Cell. 2015 Jun 18;161(7):1606-18
pubmed: 26052047
Methods Enzymol. 2016;569:331-53
pubmed: 26778566
Neuron. 2014 Apr 16;82(2):350-64
pubmed: 24742460
Nat Neurosci. 2013 Nov;16(11):1576-87
pubmed: 24097039
Nature. 2014 Nov 13;515(7526):216-21
pubmed: 25363768
J Neurosci. 2008 Oct 15;28(42):10674-86
pubmed: 18923043
Science. 2022 May 20;376(6595):eabn6204
pubmed: 35587969
J Neurosci. 2005 Jun 15;25(24):5691-9
pubmed: 15958735
Ann Neurol. 2018 Sep;84(3):436-451
pubmed: 30048010
Development. 2016 May 15;143(10):1753-65
pubmed: 27034423
Oncogene. 1998 Jan 15;16(2):147-52
pubmed: 9464532
Glia. 2007 Jun;55(8):822-30
pubmed: 17366550
J Neurosci. 2021 Sep 1;41(35):7350-7362
pubmed: 34301831
Mol Cell Biol. 2005 May;25(9):3726-36
pubmed: 15831477
J Neurosci. 2010 May 19;30(20):7072-7
pubmed: 20484649
Neuron. 2011 Jan 13;69(1):61-76
pubmed: 21220099
Brain. 2019 Nov 1;142(11):3351-3359
pubmed: 31504246
Cell. 2017 May 4;169(4):621-635.e16
pubmed: 28475893
Neuron. 2004 Jan 8;41(1):57-69
pubmed: 14715135
Int J Dev Biol. 2022;66(1-2-3):43-49
pubmed: 34881792
EMBO Mol Med. 2022 Jul 7;14(7):e15608
pubmed: 35698786
Mol Cytogenet. 2012 Jun 11;5(1):30
pubmed: 22686481
Neuron. 2011 Mar 24;69(6):1069-84
pubmed: 21435554
Dev Biol. 2011 Oct 1;358(1):9-22
pubmed: 21803034
Dev Cell. 2018 Apr 9;45(1):10-32
pubmed: 29634931
Cell Res. 2018 Feb;28(2):221-248
pubmed: 29086765
Cell. 2003 Oct 31;115(3):343-54
pubmed: 14636561
Handb Exp Pharmacol. 2017;235:123-152
pubmed: 27469496
Mol Psychiatry. 2021 Dec;26(12):7225-7246
pubmed: 34127816
Cereb Cortex. 2012 Mar;22(3):680-92
pubmed: 21690261
Eur J Neurosci. 2013 Jul;38(1):2019-29
pubmed: 23651101
Cell. 2000 Oct 13;103(2):239-52
pubmed: 11057897
J Neurosci. 2007 Oct 10;27(41):10935-46
pubmed: 17928435
Cell Rep. 2021 Jan 26;34(4):108644
pubmed: 33503438
Cell. 2018 Feb 22;172(5):1063-1078.e19
pubmed: 29474907
Neuron. 2011 Feb 24;69(4):763-79
pubmed: 21338885
Nat Rev Neurosci. 2001 Nov;2(11):780-90
pubmed: 11715055
Nat Neurosci. 2012 Sep;15(9):1201-10
pubmed: 22842144
Nat Methods. 2008 Jul;5(7):605-7
pubmed: 18536722
Cell Rep. 2013 Aug 29;4(4):738-50
pubmed: 23954789
J Hum Genet. 2023 Jul;68(7):445-453
pubmed: 36864284
J Neurosci. 2007 Mar 21;27(12):3078-89
pubmed: 17376969
J Neurosci. 2010 Sep 8;30(36):12050-62
pubmed: 20826668
Nat Commun. 2021 Jun 16;12(1):3653
pubmed: 34135323
Nat Commun. 2022 Sep 5;13(1):5217
pubmed: 36064547
Dev Neurosci. 2008;30(1-3):132-43
pubmed: 18075261
Dev Neurobiol. 2014 Jan;74(1):63-81
pubmed: 24124161
Cereb Cortex. 2015 Apr;25(4):991-1003
pubmed: 24142862
Nat Neurosci. 2015 Mar;18(3):393-401
pubmed: 25664912
Front Oncol. 2018 Feb 12;8:24
pubmed: 29484286
J Biol Chem. 2010 Aug 6;285(32):24834-44
pubmed: 20516067
Eur J Neurosci. 2014 Feb;39(4):531-47
pubmed: 24236816
Blood. 2011 Jul 28;118(4):1099-108
pubmed: 21551229
Nat Commun. 2014 Nov 20;5:5524
pubmed: 25409778
Am J Hum Genet. 2018 Dec 6;103(6):1009-1021
pubmed: 30471716
Mol Biol Cell. 2014 Dec 15;25(25):4063-71
pubmed: 25355950