The associations between 2D:4D ratio and behavior problems among Chinese preschool children: A cross-sectional study.
2D:4D
Behavior problems
Depression
Digit ratio
Preschool children
Testosterone
Journal
Early human development
ISSN: 1872-6232
Titre abrégé: Early Hum Dev
Pays: Ireland
ID NLM: 7708381
Informations de publication
Date de publication:
11 2023
11 2023
Historique:
received:
20
08
2023
revised:
28
09
2023
accepted:
29
09
2023
medline:
6
11
2023
pubmed:
6
10
2023
entrez:
5
10
2023
Statut:
ppublish
Résumé
Digit ratio (2D:4D) is considered a biomarker of prenatal androgen activity, the prenatal hormone exposure may affect children's psychology and behavior. The aim of this study was to analyze the associations between 2D:4D ratio and behavior problems in Chinese preschool children, and to provide ideas for early intervention of children's behavior problems. A total of 548 Chinese preschool children aged 3-6 years were recruited using a stratified cluster sampling method. The Child Behavior Checklist (CBCL) was used to assess the children's behavior. Basic information of the children and their parents was also collected, finger length was directly measured by electronic vernier caliper. We found that sex and age of the child, mother's educational level, and whether the child was an only child were the influencing factors of behavior problems (P < 0.05). Right-handed 2D:4D was negatively correlated with parent-reported anxiety/depression (P < 0.05), father-reported aggression (P < 0.05) and attention problems (P < 0.01), that is, high levels of testosterone may increase the risk of anxiety and depression, our results were in contrast to previous studies. The 2D:4D ratio may be related to behavior problems among Chinese preschool children, and prenatal testosterone exposure may be an important factor affecting behavior problems.
Sections du résumé
BACKGROUND
Digit ratio (2D:4D) is considered a biomarker of prenatal androgen activity, the prenatal hormone exposure may affect children's psychology and behavior.
OBJECTIVE
The aim of this study was to analyze the associations between 2D:4D ratio and behavior problems in Chinese preschool children, and to provide ideas for early intervention of children's behavior problems.
METHODS
A total of 548 Chinese preschool children aged 3-6 years were recruited using a stratified cluster sampling method. The Child Behavior Checklist (CBCL) was used to assess the children's behavior. Basic information of the children and their parents was also collected, finger length was directly measured by electronic vernier caliper.
RESULTS
We found that sex and age of the child, mother's educational level, and whether the child was an only child were the influencing factors of behavior problems (P < 0.05). Right-handed 2D:4D was negatively correlated with parent-reported anxiety/depression (P < 0.05), father-reported aggression (P < 0.05) and attention problems (P < 0.01), that is, high levels of testosterone may increase the risk of anxiety and depression, our results were in contrast to previous studies.
CONCLUSION
The 2D:4D ratio may be related to behavior problems among Chinese preschool children, and prenatal testosterone exposure may be an important factor affecting behavior problems.
Identifiants
pubmed: 37797473
pii: S0378-3782(23)00167-6
doi: 10.1016/j.earlhumdev.2023.105871
pii:
doi:
Substances chimiques
Androgens
0
Testosterone
3XMK78S47O
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
105871Informations de copyright
Copyright © 2023 The Authors. Published by Elsevier B.V. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest None.