Association of Vegetarian and Vegan Diets with Cardiovascular Health: An Umbrella Review of Meta-Analysis of Observational Studies and Randomized Trials.
cardiovascular outcomes
cerebrovascular disease
umbrella review
vegetarian diets
Journal
Nutrients
ISSN: 2072-6643
Titre abrégé: Nutrients
Pays: Switzerland
ID NLM: 101521595
Informations de publication
Date de publication:
22 Sep 2023
22 Sep 2023
Historique:
received:
31
07
2023
revised:
22
08
2023
accepted:
19
09
2023
medline:
23
10
2023
pubmed:
14
10
2023
entrez:
14
10
2023
Statut:
epublish
Résumé
Cardiovascular diseases (CVDs) are leading global causes of mortality. Unhealthy diets have been linked to an increased risk of CVD, while plant-based diets have shown potential protective effects. This umbrella review summarizes the evidence on the association between vegetarian diets and cardiovascular and cerebrovascular diseases. PubMed, Scopus, Embase, CINAHL, Cochrane, and Web of Science were consulted. Meta-analyses grouped by author and outcome were performed. The heterogeneity was evaluated using I There was a 41.2% risk reduction for cerebrovascular disease. CVD incidence had a 29% reduced risk. CVD mortality had a 13.8% risk reduction, while IHD incidence had a 24.1% reduction, but with high heterogeneity. IHD mortality showed a significant 32.1% risk reduction. Ischemic stroke had a significant 32.9% risk reduction across six studies. Stroke incidence showed a significant 39.1% risk reduction in a single study. There was a non-significant 11.6% risk reduction for stroke mortality with moderate heterogeneity. Healthier diets are associated with reduced risks of cerebrovascular disease, CVD incidence, IHD mortality, and ischemic stroke. However, evidence quality and consistency vary, emphasizing the need for more research. Policymakers and healthcare professionals should prioritize promoting healthy diets for CVD prevention.
Sections du résumé
BACKGROUND
BACKGROUND
Cardiovascular diseases (CVDs) are leading global causes of mortality. Unhealthy diets have been linked to an increased risk of CVD, while plant-based diets have shown potential protective effects. This umbrella review summarizes the evidence on the association between vegetarian diets and cardiovascular and cerebrovascular diseases.
METHODS
METHODS
PubMed, Scopus, Embase, CINAHL, Cochrane, and Web of Science were consulted. Meta-analyses grouped by author and outcome were performed. The heterogeneity was evaluated using I
RESULTS
RESULTS
There was a 41.2% risk reduction for cerebrovascular disease. CVD incidence had a 29% reduced risk. CVD mortality had a 13.8% risk reduction, while IHD incidence had a 24.1% reduction, but with high heterogeneity. IHD mortality showed a significant 32.1% risk reduction. Ischemic stroke had a significant 32.9% risk reduction across six studies. Stroke incidence showed a significant 39.1% risk reduction in a single study. There was a non-significant 11.6% risk reduction for stroke mortality with moderate heterogeneity.
CONCLUSION
CONCLUSIONS
Healthier diets are associated with reduced risks of cerebrovascular disease, CVD incidence, IHD mortality, and ischemic stroke. However, evidence quality and consistency vary, emphasizing the need for more research. Policymakers and healthcare professionals should prioritize promoting healthy diets for CVD prevention.
Identifiants
pubmed: 37836394
pii: nu15194103
doi: 10.3390/nu15194103
pmc: PMC10574056
pii:
doi:
Types de publication
Meta-Analysis
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Références
Foods. 2021 Dec 08;10(12):
pubmed: 34945602
Int J Cardiol. 2014 Oct 20;176(3):680-6
pubmed: 25149402
Open Med. 2009;3(3):e123-30
pubmed: 21603045
Adv Nutr. 2020 Jul 1;11(4):815-833
pubmed: 32059053
Evid Based Ment Health. 2018 Aug;21(3):95-100
pubmed: 30006442
Nutrients. 2017 Aug 09;9(8):
pubmed: 28792455
Front Cardiovasc Med. 2021 Nov 05;8:756810
pubmed: 34805312
Trials. 2017 Sep 11;18(1):425
pubmed: 28893297
BMJ. 1997 Sep 13;315(7109):629-34
pubmed: 9310563
Eur J Nutr. 2021 Sep;60(6):2893-2903
pubmed: 33377996
Nutrients. 2021 Aug 29;13(9):
pubmed: 34578897
BMJ. 2011 Feb 10;342:d549
pubmed: 21310794
Nutrients. 2019 Feb 05;11(2):
pubmed: 30764511
Crit Rev Food Sci Nutr. 2022;62(28):7760-7772
pubmed: 33951994
J Am Coll Cardiol. 2020 Dec 22;76(25):2982-3021
pubmed: 33309175
Ann Nutr Metab. 2012;60(4):233-40
pubmed: 22677895
Adv Nutr. 2018 Jul 1;9(4):367-377
pubmed: 30032218
BMJ. 2021 Mar 29;372:n71
pubmed: 33782057
Rev Lat Am Enfermagem. 2007 May-Jun;15(3):508-11
pubmed: 17653438
J Am Coll Cardiol. 2015 Oct 6;66(14):1590-1614
pubmed: 26429085
Nutrients. 2023 May 16;15(10):
pubmed: 37242214
Eur J Nutr. 2023 Feb;62(1):51-69
pubmed: 36030329
Circ Res. 2017 Sep 1;121(6):677-694
pubmed: 28860318
J Clin Epidemiol. 2020 May;121:81-90
pubmed: 32004673
Int J Mol Sci. 2020 Oct 15;21(20):
pubmed: 33076218
BMJ. 2017 Sep 21;358:j4008
pubmed: 28935701
Front Nutr. 2019 Jun 13;6:80
pubmed: 31263700
BMJ Ment Health. 2023 Feb;26(1):
pubmed: 36792173
Crit Rev Food Sci Nutr. 2017 Nov 22;57(17):3640-3649
pubmed: 26853923
Am J Prev Cardiol. 2021 Apr 09;7:100182
pubmed: 34611632
Lancet Diabetes Endocrinol. 2014 Aug;2(8):634-47
pubmed: 24842598
Clin Nutr. 2020 Nov;39(11):3283-3307
pubmed: 32204974
Nutrients. 2020 Apr 15;12(4):
pubmed: 32326404
Circulation. 2021 Dec 7;144(23):e472-e487
pubmed: 34724806
Cochrane Database Syst Rev. 2021 Feb 25;2:CD013501
pubmed: 33629376