Negative pressure wound therapy for flap closed-incisions after 3D-printed prosthesis implantation in patients with chronic osteomyelitis with soft tissue defects.
Chronic osteomyelitis
Closed-incision
Negative pressure wound therapy
Soft tissue defects
Journal
BMC musculoskeletal disorders
ISSN: 1471-2474
Titre abrégé: BMC Musculoskelet Disord
Pays: England
ID NLM: 100968565
Informations de publication
Date de publication:
19 Oct 2023
19 Oct 2023
Historique:
received:
25
09
2023
accepted:
15
10
2023
medline:
23
10
2023
pubmed:
20
10
2023
entrez:
20
10
2023
Statut:
epublish
Résumé
The flap closed-incisions healing after 3D-printed prosthesis implantation in Chronic Osteomyelitis with Soft Tissue Defects (COSTD) is critical. This study aimed to explore the safety and effectiveness of Negative Pressure Wound Therapy (NPWT) in promoting flap closed-incisions healing. Retrospective analysis of clinical data was performed, including baseline, surgical and hospitalization information. The efficacy of NPWT was assessed by comparing the ASEPSIS scores, Visual Analogue Scale (VAS), Activity of Daily Living Scale (ADLS), and Lower Extremity Functional Scale (LEFS), as well as the major postoperative complications. The study included 20 patients, 13 received conventional dressing (Control group) and 7 received NPWT treatment (NPWT group). These two groups exhibited a notable disparity in the distribution of ASEPSIS scores, and the median scores were 24 in Control group and 9 in NPWT group (p = 0.001). Eight patients in the Control group experienced major incisional complications, including 7 cases of exudation, 3 cases of infection, 2 cases of non-healing, and 1 case of dehiscence, while none were observed in the NPWT group (p = 0.015). The VAS, ADLS, and LEFS scores were significantly improved in the NPWT group compared to the Control group (p = 0.003, 0.017, and 0.043, respectively). The study findings suggest that NPWT applied to the healing process of flap closed-incisions after 3D prosthesis implantation in patients with COSTD can reduce the occurrence of postoperative major complications and promote the recovery of lower limb function and daily activities, which should be recommended for clinical practice.
Sections du résumé
BACKGROUND
BACKGROUND
The flap closed-incisions healing after 3D-printed prosthesis implantation in Chronic Osteomyelitis with Soft Tissue Defects (COSTD) is critical. This study aimed to explore the safety and effectiveness of Negative Pressure Wound Therapy (NPWT) in promoting flap closed-incisions healing.
METHODS
METHODS
Retrospective analysis of clinical data was performed, including baseline, surgical and hospitalization information. The efficacy of NPWT was assessed by comparing the ASEPSIS scores, Visual Analogue Scale (VAS), Activity of Daily Living Scale (ADLS), and Lower Extremity Functional Scale (LEFS), as well as the major postoperative complications.
RESULTS
RESULTS
The study included 20 patients, 13 received conventional dressing (Control group) and 7 received NPWT treatment (NPWT group). These two groups exhibited a notable disparity in the distribution of ASEPSIS scores, and the median scores were 24 in Control group and 9 in NPWT group (p = 0.001). Eight patients in the Control group experienced major incisional complications, including 7 cases of exudation, 3 cases of infection, 2 cases of non-healing, and 1 case of dehiscence, while none were observed in the NPWT group (p = 0.015). The VAS, ADLS, and LEFS scores were significantly improved in the NPWT group compared to the Control group (p = 0.003, 0.017, and 0.043, respectively).
CONCLUSIONS
CONCLUSIONS
The study findings suggest that NPWT applied to the healing process of flap closed-incisions after 3D prosthesis implantation in patients with COSTD can reduce the occurrence of postoperative major complications and promote the recovery of lower limb function and daily activities, which should be recommended for clinical practice.
Identifiants
pubmed: 37858142
doi: 10.1186/s12891-023-06970-1
pii: 10.1186/s12891-023-06970-1
pmc: PMC10585842
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
827Informations de copyright
© 2023. BioMed Central Ltd., part of Springer Nature.
Références
Arch Plast Surg. 2018 Jul;45(4):314-318
pubmed: 30037190
J Plast Reconstr Aesthet Surg. 2009 Dec;62(12):1701-8
pubmed: 19071078
Br J Surg. 2014 Dec;101(13):1627-36
pubmed: 25294112
Lancet. 2004 Jul 24-30;364(9431):369-79
pubmed: 15276398
Wound Repair Regen. 2004 Nov-Dec;12(6):600-6
pubmed: 15555050
Surg Innov. 2012 Mar;19(1):67-75
pubmed: 21868417
Trans R Soc Trop Med Hyg. 2010 Feb;104(2):139-42
pubmed: 19709706
Ann Plast Surg. 1997 Jun;38(6):553-62
pubmed: 9188970
Plast Reconstr Surg. 2008 Sep;122(3):988
pubmed: 18766075
Acta Orthop Belg. 2003 Dec;69(6):481-94
pubmed: 14748102
N Engl J Med. 1970 Feb 5;282(6):316-22
pubmed: 4987436
J Plast Reconstr Aesthet Surg. 2012 May;65(5):640-9
pubmed: 22137686
Int Wound J. 2022 Dec;19(8):1980-1989
pubmed: 35302286
J Neurol Surg B Skull Base. 2014 Oct;75(5):324-31
pubmed: 25302143
N Engl J Med. 1980 Aug 14;303(7):360-70
pubmed: 6993944
Mol Med Rep. 2014 May;9(5):1749-54
pubmed: 24584462
Int J Surg. 2014;12 Suppl 2:S64-S68
pubmed: 25159226
Int Wound J. 2022 Oct;19(6):1349-1356
pubmed: 34935287
Ther Clin Risk Manag. 2021 Jan 19;17:65-71
pubmed: 33500621
Plast Reconstr Surg. 2021 Jan 1;147(1S-1):9S-15S
pubmed: 33347058
Int Wound J. 2023 Mar;20(3):768-773
pubmed: 36382601
Clin Microbiol Infect. 2020 May;26(5):572-578
pubmed: 31446152
Plast Reconstr Surg. 2021 Nov 1;148(5):715e-719e
pubmed: 34705771
Ann Plast Surg. 2010 Dec;65(6):555-9
pubmed: 21042193
Lancet. 1986 Feb 8;1(8476):311-3
pubmed: 2868173
Arch Plast Surg. 2018 Jul;45(4):298-303
pubmed: 30037188
Int Wound J. 2011 Feb;8(1):56-62
pubmed: 21167000
J Formos Med Assoc. 2005 Jan;104(1):29-33
pubmed: 15660174
N Engl J Med. 1982 Feb 4;306(5):294-5
pubmed: 7054701
J Arthroplasty. 2016 May;31(5):1047-52
pubmed: 26712346
J Orthop Surg Res. 2018 May 18;13(1):117
pubmed: 29776425
J Orthop Surg Res. 2009 May 09;4:14
pubmed: 19426531
World J Surg. 2020 May;44(5):1526-1537
pubmed: 31900568
Plast Reconstr Surg. 2018 Mar;141(3):773-783
pubmed: 29485576
Plast Reconstr Surg. 2015 Sep;136(3):592-602
pubmed: 26313829