Synthesis and Characterization of a Biopolymer Pectin/Ethanolic Extract from Olive Mill Wastewater: In Vitro Safety and Efficacy Tests on Skin Wound Healing.


Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
11 Oct 2023
Historique:
received: 25 06 2023
revised: 27 09 2023
accepted: 05 10 2023
medline: 30 10 2023
pubmed: 28 10 2023
entrez: 28 10 2023
Statut: epublish

Résumé

Wound-healing delay is one of the major problems of type 2 diabetes, representing also a clinical emergency in non-healing chronic wounds. Natural antioxidants show interesting wound-healing properties, including those extracted from waste derived from olive oil production. Olive mill wastewater is one of the main by-products of the olive oil-making process, and it is rich in high-value secondary metabolites, mainly hydroxytyrosol. We proposed an eco-friendly extraction method, employing both ultrasound-assisted and Soxhlet techniques and ethanol as a solvent, to recover valuable molecules from Roggianella cv (

Identifiants

pubmed: 37894755
pii: ijms242015075
doi: 10.3390/ijms242015075
pmc: PMC10606433
pii:
doi:

Substances chimiques

Wastewater 0
Pectins 89NA02M4RX
Olive Oil 0
Antioxidants 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Références

Foods. 2020 Oct 29;9(11):
pubmed: 33137916
Toxicol Res. 2016 Oct;32(4):311-316
pubmed: 27818733
J Biomol Struct Dyn. 2023 Apr 3;:1-12
pubmed: 37011015
Foods. 2022 Jan 08;11(2):
pubmed: 35053891
Biotech Histochem. 2021 Oct;96(7):536-545
pubmed: 33047988
Cell Biol Toxicol. 2009 Apr;25(2):109-26
pubmed: 18204907
Biomolecules. 2020 Sep 30;10(10):
pubmed: 33008084
Drug Deliv Transl Res. 2022 Aug;12(8):1881-1894
pubmed: 35359261
Antioxidants (Basel). 2019 Feb 06;8(2):
pubmed: 30736314
Drug Dev Ind Pharm. 2021 Feb;47(2):215-224
pubmed: 33317339
J Agric Food Chem. 2021 Feb 3;69(4):1234-1241
pubmed: 33301331
Antioxidants (Basel). 2019 Jul 20;8(7):
pubmed: 31330803
Antioxidants (Basel). 2021 Jun 24;10(7):
pubmed: 34202671
J Ethnopharmacol. 2023 Sep 15;313:116579
pubmed: 37142146
Antioxidants (Basel). 2023 Mar 02;12(3):
pubmed: 36978870
Pharmaceutics. 2023 Apr 29;15(5):
pubmed: 37242616
Front Nutr. 2022 Jan 05;8:782693
pubmed: 35071293
Biomaterials. 2017 Apr;122:34-47
pubmed: 28107663
J Ethnopharmacol. 2022 Nov 15;298:115663
pubmed: 36038091
Eng Regen. 2023 Sep;4(3):265-276
pubmed: 37234753
J Invest Dermatol. 1992 Jan;98(1):3-11
pubmed: 1728638
J Agric Food Chem. 2021 Jul 7;69(26):7268-7284
pubmed: 34180235
Adv Drug Deliv Rev. 2018 Apr;129:344-351
pubmed: 29501701
Toxicol In Vitro. 2000 Dec;14(6):513-6
pubmed: 11033062
Phytomedicine. 2023 Jul;115:154824
pubmed: 37119762
Antioxidants (Basel). 2020 Sep 03;9(9):
pubmed: 32899385

Auteurs

Francesca Aiello (F)

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.

Rocco Malivindi (R)

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.

Marisa Francesca Motta (MF)

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.

Pasquale Crupi (P)

Interdisciplinary Department of Medicine, University Aldo Moro Bari, 70121 Bari, Italy.

Rosa Nicoletti (R)

Council for Agricultural Research and Economics (CREA), Research Centre for Olive, Fruit and Citrus Crops, Via Settimio Severo 83, 87036 Rende, Italy.
DICEM-Department of European and Mediterranean Cultures: Architecture, Environment, and Cultural Heritage, University of Basilicata, Matera, Via Lanera, 20, 75100 Matera, Italy.

Cinzia Benincasa (C)

Council for Agricultural Research and Economics (CREA), Research Centre for Olive, Fruit and Citrus Crops, Via Settimio Severo 83, 87036 Rende, Italy.

Maria Lisa Clodoveo (ML)

Interdisciplinary Department of Medicine, University Aldo Moro Bari, 70121 Bari, Italy.

Vittoria Rago (V)

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.

Umile Gianfranco Spizzirri (UG)

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.
Ionian Department of Law, Economics and Environment, University of Bari Aldo Moro, 74123 Taranto, Italy.

Donatella Restuccia (D)

Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende, Italy.

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Classifications MeSH