Postnatal Corticosteroids To Prevent Bronchopulmonary Dysplasia.


Journal

NeoReviews
ISSN: 1526-9906
Titre abrégé: Neoreviews
Pays: United States
ID NLM: 101085360

Informations de publication

Date de publication:
01 Nov 2023
Historique:
medline: 2 11 2023
pubmed: 1 11 2023
entrez: 31 10 2023
Statut: ppublish

Résumé

Bronchopulmonary dysplasia (BPD) is a common, severe chronic respiratory disease that affects very preterm infants. In utero and postnatal exposure to proinflammatory stimuli contribute to the pathophysiology of BPD. Corticosteroids, because of their potent anti-inflammatory properties, may decrease respiratory morbidity and reduce the risk of BPD in very preterm infants. However, these medications can have adverse effects on the developing brain and other organ systems. This review examines current evidence on the risks and benefits of postnatal corticosteroids used to prevent BPD in preterm infants.

Identifiants

pubmed: 37907402
pii: 194500
doi: 10.1542/neo.24-11-e691
doi:

Substances chimiques

Glucocorticoids 0
Dexamethasone 7S5I7G3JQL
Adrenal Cortex Hormones 0

Types de publication

Review Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e691-e703

Informations de copyright

Copyright © 2023 by the American Academy of Pediatrics.

Auteurs

Erik A Jensen (EA)

Division of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia and University of Pennsylvania, Philadelphia, PA.

Kristi L Watterberg (KL)

Department of Pediatrics, University of New Mexico Health Sciences Center, Albuquerque, NM.

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Classifications MeSH