FATP4 deletion in liver cells induces elevation of extracellular lipids via metabolic channeling towards triglycerides and lipolysis.
Acyl-CoA synthetases
Blood lipids
Fatty-acid transport proteins
Genetic predisposition
Hepatic lipases
Triglyceride lipolysis
β-oxidation
Journal
Biochemical and biophysical research communications
ISSN: 1090-2104
Titre abrégé: Biochem Biophys Res Commun
Pays: United States
ID NLM: 0372516
Informations de publication
Date de publication:
20 Dec 2023
20 Dec 2023
Historique:
received:
14
08
2023
revised:
13
10
2023
accepted:
26
10
2023
medline:
22
11
2023
pubmed:
7
11
2023
entrez:
6
11
2023
Statut:
ppublish
Résumé
Evidence from mice with global deletion of fatty-acid transport protein4 (FATP4) indicates its role on β-oxidation and triglycerides (TG) metabolism. We reported that plasma glycerol and free fatty acids (FA) were increased in liver-specific Fatp4 deficient (L-FATP4
Identifiants
pubmed: 37931418
pii: S0006-291X(23)01255-X
doi: 10.1016/j.bbrc.2023.149161
pii:
doi:
Substances chimiques
Triglycerides
0
Oleic Acid
2UMI9U37CP
Glycerol
PDC6A3C0OX
Lipoproteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
149161Informations de copyright
Copyright © 2023 Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.