Simone Staffer

Affiliations

Internal Medicine IV, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany.

Publications (14)

Myeloid- and hepatocyte-specific deletion of group VIA calcium-independent phospholipase A2 leads to dichotomous opposing phenotypes during MCD diet-induced NASH.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Chutima Jansakun , Warangkana Chunglok , Sandro Altamura , Martina Muckenthaler , Simone Staffer , Sabine Tuma-Kellner , Uta Merle , Walee Chamulitrat

Phosphatidylcholine Passes by Paracellular Transport to the Apical Side of the Polarized Biliary Tumor Cell Line Mz-ChA-1.

International journal of molecular sciences

Avec: Wolfgang Stremmel , Simone Staffer , Ralf Weiskirchen

The Bile Acid-Phospholipid Conjugate Ursodeoxycholyl-Lysophosphatidylethanolamide (UDCA-LPE) Disintegrates the Lipid Backbone of Raft Plasma Membrane Domains by the Removal of the Membrane Phospholipase A2.

International journal of molecular sciences

Avec: Wolfgang Stremmel , Simone Staffer , Gert Fricker , Ralf Weiskirchen

Shear-Enhanced Dynamic Adhesion of Lactobacillus rhamnosus GG on Intestinal Epithelia: Correlative Effect of Protein Expression and Interface Mechanics.

Langmuir : the ACS journal of surfaces and colloids

Avec: Maryam Eshrati , Federico Amadei , Simone Staffer , Wolfgang Stremmel , Motomu Tanaka

iPla2β deficiency in mice fed with MCD diet does not correct the defect of phospholipid remodeling but attenuates hepatocellular injury via an inhibition of lipid uptake genes.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: Xingya Zhu , Hongying Gan-Schreier , Ann-Christin Otto , Yuting Cheng , Simone Staffer , Sabine Tuma-Kellner , Alexandra Ganzha , Gerhard Liebisch , Walee Chamulitrat

FATP4 deletion in liver cells induces elevation of extracellular lipids via metabolic channeling towards triglycerides and lipolysis.

Biochemical and biophysical research communications

Avec: Huili Li , Jessica Seessle , Simone Staffer , Sabine Tuma-Kellner , Gernot Poschet , Thomas Herrmann , Walee Chamulitrat

Myeloid-specific deletion of group VIA calcium-independent phospholipase A2 induces pro-inflammatory LPS response predominantly in male mice via MIP-1α activation.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Lukas Klement , Chutima Jansakun , Bin Yan , Simone Staffer , Sabine Tuma-Kellner , Sandro Altamura , Martina Muckenthaler , Uta Merle , Walee Chamulitrat

The Detergent Effect of Mesalazine Interferes with Phosphatidylcholine Binding to Mucin 2.

Inflammatory intestinal diseases

Avec: Wolfgang Stremmel , Simone Staffer , Sven Gehrke

Constitutive oxidants from hepatocytes of male iPLA2β-null mice increases the externalization of phosphatidylethanolamine on plasma membrane.

Free radical research

Avec: Heng Yeng Wong , Monika Langlotz , Hongying Gan-Schreier , Weihong Xu , Simone Staffer , Sabine Tuma-Kellner , Gerhard Liebisch , Uta Merle , Walee Chamulitrat

Enterocyte-specific FATP4 deficiency elevates blood lipids via a shift from polar to neutral lipids in distal intestine.

American journal of physiology. Gastrointestinal and liver physiology

Avec: Jessica Seeßle , Gerhard Liebisch , Simone Staffer , Sabine Tuma-Kellner , Uta Merle , Thomas Herrmann , Walee Chamulitrat

Group VIA phospholipase A2 deficiency in mice chronically fed with high-fat-diet attenuates hepatic steatosis by correcting a defect of phospholipid remodeling.

Biochimica et biophysica acta. Molecular and cell biology of lipids

Avec: Ann-Christin Otto , Hongying Gan-Schreier , Xingya Zhu , Sabine Tuma-Kellner , Simone Staffer , Alexandra Ganzha , Gerhard Liebisch , Walee Chamulitrat

FATP4 inactivation in cultured macrophages attenuates M1- and ER stress-induced cytokine release via a metabolic shift towards triacylglycerides.

The Biochemical journal

Avec: Yuling Zhang , Ning Wu , Hongying Gan-Schreier , Feng Xu , Sabine Tuma-Kellner , Simone Staffer , Jessica Seeßle , Uta Merle , Walee Chamulitrat

Methionine- and Choline-Deficient Diet Enhances Adipose Lipolysis and Leptin Release in aP2-Cre Fatp4-Knockout Mice.

Molecular nutrition & food research

Avec: Yuting Cheng , Hongying Gan-Schreier , Jessica Seeßle , Simone Staffer , Sabine Tuma-Kellner , Denis Khnykin , Wolfgang Stremmel , Uta Merle , Thomas Herrmann , Walee Chamulitrat

Myeloid-specific fatty acid transport protein 4 deficiency induces a sex-dimorphic susceptibility for nonalcoholic steatohepatitis in mice fed a high-fat, high-cholesterol diet.

American journal of physiology. Gastrointestinal and liver physiology

Avec: Deniz Göcebe , Chutima Jansakun , Yuling Zhang , Simone Staffer , Sabine Tuma-Kellner , Sandro Altamura , Martina U Muckenthaler , Uta Merle , Thomas Herrmann , Walee Chamulitrat

Réseau de co-auteurs

Sabine Tuma-Kellner 10 collaborations

Walee Chamulitrat 10 collaborations

Uta Merle 7 collaborations

Wolfgang Stremmel 5 collaborations

Hongying Gan-Schreier 5 collaborations

Gerhard Liebisch 4 collaborations

Thomas Herrmann 4 collaborations

Chutima Jansakun 3 collaborations

Sandro Altamura 3 collaborations

Jessica Seeßle 3 collaborations

Martina Muckenthaler 2 collaborations

Ralf Weiskirchen 2 collaborations

Xingya Zhu 2 collaborations

Ann-Christin Otto 2 collaborations

Yuting Cheng 2 collaborations

Alexandra Ganzha 2 collaborations

Yuling Zhang 2 collaborations

Warangkana Chunglok 1 collaboration

Gert Fricker 1 collaboration

Maryam Eshrati 1 collaboration

Federico Amadei 1 collaboration

Motomu Tanaka 1 collaboration

Huili Li 1 collaboration

Jessica Seessle 1 collaboration

Gernot Poschet 1 collaboration

Lukas Klement 1 collaboration

Bin Yan 1 collaboration

Sven Gehrke 1 collaboration

Heng Yeng Wong 1 collaboration

Monika Langlotz 1 collaboration

Weihong Xu 1 collaboration

Ning Wu 1 collaboration

Feng Xu 1 collaboration

Denis Khnykin 1 collaboration

Deniz Göcebe 1 collaboration

Martina U Muckenthaler 1 collaboration