Scandium Radioisotopes-Toward New Targets and Imaging Modalities.

Radiopharmaceuticals / therapeutic use Scandium / chemistry Radioisotopes / therapeutic use Precision Medicine
radiochemical separation radiolabeling radiopharmaceuticals scandium radioisotopes theranostics

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
19 Nov 2023
Historique:
received: 31 08 2023
revised: 15 11 2023
accepted: 15 11 2023
medline: 27 11 2023
pubmed: 25 11 2023
entrez: 25 11 2023
Statut: epublish

Résumé

The concept of theranostics uses radioisotopes of the same or chemically similar elements to label biological ligands in a way that allows the use of diagnostic and therapeutic radiation for a combined diagnosis and treatment regimen. For scandium, radioisotopes -43 and -44 can be used as diagnostic markers, while radioisotope scandium-47 can be used in the same configuration for targeted therapy. This work presents the latest achievements in the production and processing of radioisotopes and briefly characterizes solutions aimed at increasing the availability of these radioisotopes for research and clinical practice.

Identifiants

DOI: 10.3390/molecules28227668 PMID: 38005390 PMC: PMC10675654
pubmed: 38005390
pii: molecules28227668
doi: 10.3390/molecules28227668
pmc: PMC10675654
pii:
doi:

Substances chimiques

Radiopharmaceuticals 0
Scandium YUJ4U1EW7R
Radioisotopes 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

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Auteurs

Krzysztof Kilian (K)

Heavy Ion Laboratory, University of Warsaw, Pasteura 5a, 02-093 Warsaw, Poland.
ORCID: 0000-0002-3812-3917

Krystyna Pyrzyńska (K)

Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.
ORCID: 0000-0002-1089-8577

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Radiopharmaceutiques › Scandium Radioisotopes-Toward New Targets and...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Terres rares › Scandium › Scandium Radioisotopes-Toward New Targets and...
questionsmedicales.fr › Produits chimiques inorganiques › Isotopes › Radio-isotopes › Scandium Radioisotopes-Toward New Targets and...
questionsmedicales.fr › Professions de santé › Médecine › Médecine clinique › Médecine de précision › Scandium Radioisotopes-Toward New Targets and...