Bioactive α-Pyrone Analogs from the Endophytic Fungus

Pyrones / chemistry Molecular Docking Simulation Glycoside Hydrolase Inhibitors / chemistry Molecular Dynamics Simulation alpha-Glucosidases / metabolism Ascomycota / chemistry Anti-Bacterial Agents / pharmacology Molecular Structure Microbial Sensitivity Tests
Diaporthe sp. endophytic fungus α-glucosidase inhibitor α-pyrone

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
12 Apr 2024
Historique:
received: 12 03 2024
revised: 05 04 2024
accepted: 10 04 2024
medline: 27 4 2024
pubmed: 27 4 2024
entrez: 27 4 2024
Statut: epublish

Résumé

Two α-pyrone analogs were isolated from the endophytic fungus

Identifiants

DOI: 10.3390/molecules29081768 PMID: 38675588
pubmed: 38675588
pii: molecules29081768
doi: 10.3390/molecules29081768
pii:
doi:

Substances chimiques

Pyrones 0
Glycoside Hydrolase Inhibitors 0
alpha-Glucosidases EC 3.2.1.20
Anti-Bacterial Agents 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Hunan Provincial Natural Science Foundation of China grants
ID : 2022JJ50294
Organisme : Hunan Provincial Department of Education Science Research Project
ID : 22B1036
Organisme : Hunan University of Medicine High-Level Talent Introduction Startup Funds
ID : 202203
Organisme : National Innovation and Entrepreneurship Training for University of PRC
ID : S202312214004, 202212214002, S202312214006

Auteurs

Zhong Wang (Z)

Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua 418000, China.

Qingxian Ma (Q)

Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua 418000, China.

Guangling Wu (G)

Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua 418000, China.

Yani Zhong (Y)

Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua 418000, China.

Bin Feng (B)

Huaihua Hospital of Traditional Chinese Medicine, Huaihua 418000, China.

Pingzhi Huang (P)

Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua 418000, China.

Aijie Li (A)

Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua 418000, China.

Genyun Tang (G)

Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua 418000, China.

Xueshuang Huang (X)

Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua 418000, China.

Hong Pu (H)

Hunan Provincial Key Laboratory for Synthetic Biology of Traditional Chinese Medicine, School of Pharmaceutical Sciences, Hunan University of Medicine, Huaihua 418000, China.

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Classifications MeSH

questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Pyrannes › Pyrones › Bioactive α-Pyrone Analogs from the Endophytic Fungus
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Bioactive α-Pyrone Analogs from the Endophytic Fungus
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Effets physiologiques des médicaments › Hypoglycémiants › Inhibiteurs des glycoside hydrolases › Bioactive α-Pyrone Analogs from the Endophytic Fungus
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › Bioactive α-Pyrone Analogs from the Endophytic Fungus
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Glycosidases › Glucosidases › alpha-Glucosidase › Bioactive α-Pyrone Analogs from the Endophytic Fungus
questionsmedicales.fr › Eucaryotes › Champignons › Ascomycota › Bioactive α-Pyrone Analogs from the Endophytic Fungus
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antibactériens › Bioactive α-Pyrone Analogs from the Endophytic Fungus
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Bioactive α-Pyrone Analogs from the Endophytic Fungus
questionsmedicales.fr › Techniques d'investigation › Évaluation préclinique de médicament › Tests de sensibilité microbienne › Bioactive α-Pyrone Analogs from the Endophytic Fungus