Crosstalk between melatonin and nitric oxide restrains Cadmium-induced oxidative stress and enhances vinblastine biosynthesis in Catharanthus roseus (L) G Don.
Catharanthus
/ metabolism
Nitric Oxide
/ metabolism
Cadmium
/ metabolism
Oxidative Stress
/ drug effects
Vinblastine
/ metabolism
Melatonin
/ metabolism
Plant Leaves
/ metabolism
Gene Expression Regulation, Plant
/ drug effects
Hydrogen Peroxide
/ metabolism
Antioxidants
/ metabolism
Plant Proteins
/ metabolism
D4H and DAT expression
Alkaloid
Antioxidant enzymes
Lipid peroxidation
Proline
Sodium nitroprusside
Journal
Plant cell reports
ISSN: 1432-203X
Titre abrégé: Plant Cell Rep
Pays: Germany
ID NLM: 9880970
Informations de publication
Date de publication:
13 May 2024
13 May 2024
Historique:
received:
29
02
2024
accepted:
02
05
2024
medline:
13
5
2024
pubmed:
13
5
2024
entrez:
12
5
2024
Statut:
epublish
Résumé
Nitric oxide functions downstream of the melatonin in adjusting Cd-induced osmotic and oxidative stresses, upregulating the transcription of D4H and DAT genes, and increasing total alkaloid and vincristine contents. A few studies have investigated the relationship between melatonin (MT) and nitric oxide (NO) in regulating defensive responses. However, it is still unclear how MT and NO interact to regulate the biosynthesis of alkaloids and vincristine in leaves of Catharanthus roseus (L.) G. Don under Cd stress. Therefore, this context was explored in the present study. Results showed that Cd toxicity (200 µM) induced oxidative stress, decreased biomass, Chl a, and Chl b content, and increased the content of total alkaloid and vinblastine in the leaves. Application of both MT (100 µM) and sodium nitroprusside (200 µM SNP, as NO donor) enhanced endogenous NO content and accordingly increased metal tolerance index, the content of total alkaloid and vinblastine. It also upregulated the transcription of two respective genes (D4H and DAT) under non-stress and Cd stress conditions. Moreover, the MT and SNP treatments reduced the content of H
Identifiants
pubmed: 38735908
doi: 10.1007/s00299-024-03229-4
pii: 10.1007/s00299-024-03229-4
doi:
Substances chimiques
Nitric Oxide
31C4KY9ESH
Cadmium
00BH33GNGH
Vinblastine
5V9KLZ54CY
Melatonin
JL5DK93RCL
Hydrogen Peroxide
BBX060AN9V
Antioxidants
0
Plant Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
139Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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