A fungal protein organizes both glycogen and cell wall glucans.

Cell Wall / metabolism Glycogen / metabolism Glucans / metabolism Fungal Proteins / metabolism Cryptococcus neoformans / metabolism Glucosyltransferases / metabolism beta-Glucans / metabolism
Cryptococcus neoformans cell wall glycogen glycogenin glycosyltransferase

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
21 May 2024
Historique:
medline: 15 5 2024
pubmed: 15 5 2024
entrez: 14 5 2024
Statut: ppublish

Résumé

Glycogen is a glucose storage molecule composed of branched α-1,4-glucan chains, best known as an energy reserve that can be broken down to fuel central metabolism. Because fungal cells have a specialized need for glucose in building cell wall glucans, we investigated whether glycogen is used for this process. For these studies, we focused on the pathogenic yeast

Identifiants

DOI: 10.1073/pnas.2319707121 PMID: 38743622
pubmed: 38743622
doi: 10.1073/pnas.2319707121
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2319707121

Subventions

Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : R01 135012
Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : R21 175875
Organisme : HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID)
ID : F31 150194

Déclaration de conflit d'intérêts

Competing interests statement:The authors declare no competing interest.

Auteurs

Liza Loza (L)

Department of Molecular Microbiology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110.
ORCID: 0000-0001-6488-451X

Tamara L Doering (TL)

Department of Molecular Microbiology, Washington University in St. Louis School of Medicine, St. Louis, MO 63110.
ORCID: 0000-0002-5179-7393

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Classifications MeSH

questionsmedicales.fr › Cellules › Structures cellulaires › Paroi cellulaire › A fungal protein organizes both glycogen and...
questionsmedicales.fr › Glucides › Polyosides › Glucanes › Glycogène › A fungal protein organizes both glycogen and...
questionsmedicales.fr › Glucides › Polyosides › Glucanes › A fungal protein organizes both glycogen and...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines fongiques › A fungal protein organizes both glycogen and...
questionsmedicales.fr › Eucaryotes › Champignons › Levures › Cryptococcus › Cryptococcus neoformans › A fungal protein organizes both glycogen and...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Transferases › Glycosyltransferase › Hexosyltransferases › Glucosyltransferases › A fungal protein organizes both glycogen and...
questionsmedicales.fr › Glucides › Polyosides › Glucanes › bêta-Glucanes › A fungal protein organizes both glycogen and...