Anilino-1,4-naphthoquinones as potent mushroom tyrosinase inhibitors:

Monophenol Monooxygenase / antagonists & inhibitors Naphthoquinones / pharmacology Enzyme Inhibitors / pharmacology Agaricales / enzymology Structure-Activity Relationship Molecular Structure Dose-Response Relationship, Drug Molecular Docking Simulation Molecular Dynamics Simulation
Tyrosinase inhibition anilino-14-naphthoquinones molecular docking molecular dynamics simulations

Journal

Journal of enzyme inhibition and medicinal chemistry
ISSN: 1475-6374
Titre abrégé: J Enzyme Inhib Med Chem
Pays: England
ID NLM: 101150203

Informations de publication

Date de publication:
Dec 2024
Historique:
medline: 30 5 2024
pubmed: 30 5 2024
entrez: 30 5 2024
Statut: ppublish

Résumé

Tyrosinase, a pivotal enzyme in melanin synthesis, is a primary target for the development of depigmenting agents. In this work,

Identifiants

DOI: 10.1080/14756366.2024.2357174 PMID: 38814149
pubmed: 38814149
doi: 10.1080/14756366.2024.2357174
doi:

Substances chimiques

Monophenol Monooxygenase EC 1.14.18.1
Naphthoquinones 0
Enzyme Inhibitors 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2357174

Auteurs

Sahachai Sabuakham (S)

Department of Biochemistry, Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Sutita Nasoontorn (S)

Department of Biochemistry, Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Napat Kongtaworn (N)

Program in Bioinformatics and Computational Biology, Graduate School, Chulalongkorn University, Bangkok, Thailand.

Thanyada Rungrotmongkol (T)

Program in Bioinformatics and Computational Biology, Graduate School, Chulalongkorn University, Bangkok, Thailand.
Center of Excellence in Structural and Computational Biology, Department of Biochemistry, Faculty of Science, Chulalongkorn University, Bangkok, Thailand.

Atit Silsirivanit (A)

Department of Biochemistry, Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Ratchanok Pingaew (R)

Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand.

Panupong Mahalapbutr (P)

Department of Biochemistry, Center for Translational Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Oxygénases › Mixed function oxygenases › Catechol oxidase › Monophenol monooxygenase › Anilino-1,4-naphthoquinones as potent mushroom...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Naphtalènes › Naphtoquinones › Anilino-1,4-naphthoquinones as potent mushroom...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Anilino-1,4-naphthoquinones as potent mushroom...
questionsmedicales.fr › Eucaryotes › Champignons › Basidiomycota › Agaricales › Anilino-1,4-naphthoquinones as potent mushroom...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Anilino-1,4-naphthoquinones as potent mushroom...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Anilino-1,4-naphthoquinones as potent mushroom...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes toxicologiques › Relation dose-effet des médicaments › Anilino-1,4-naphthoquinones as potent mushroom...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Anilino-1,4-naphthoquinones as potent mushroom...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › Anilino-1,4-naphthoquinones as potent mushroom...