Using Microfluidic Hepatic Spheroid Cultures to Assess Liver Toxicity of T-2 Mycotoxin.

T-2 Toxin / toxicity Humans Hep G2 Cells Spheroids, Cellular / drug effects Liver / drug effects Coculture Techniques Microfluidics / methods Hepatocytes / drug effects Cell Survival / drug effects
HepG2 cells T-2 cytotoxicity microfluidic devices spheroids

Journal

Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052

Informations de publication

Date de publication:
24 May 2024
Historique:
received: 27 04 2024
revised: 10 05 2024
accepted: 22 05 2024
medline: 19 6 2024
pubmed: 19 6 2024
entrez: 19 6 2024
Statut: epublish

Résumé

The

Identifiants

DOI: 10.3390/cells13110900 PMID: 38891032
pubmed: 38891032
pii: cells13110900
doi: 10.3390/cells13110900
pii:
doi:

Substances chimiques

T-2 Toxin I3FL5NM3MO

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIH HHS
ID : 1R01DK134661-24A1
Pays : United States

Auteurs

Mercedes Taroncher (M)

Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55901, USA.
Research Group in Alternative Methods for Determining Toxics Effects and Risk Assessment of Contaminants and Mixtures (RiskTox), Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av. Vicent Andrés Estellés s/n, 46100 Valencia, Spain.
ORCID: 0000-0002-8752-0951

Alan M Gonzalez-Suarez (AM)

Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55901, USA.
ORCID: 0000-0001-6442-4353

Kihak Gwon (K)

Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55901, USA.

Samuel Romero (S)

Centro de Investigación en Matemáticas Unidad Monterrey, Apodaca 66628, NL, Mexico.

Angel D Reyes-Figueroa (AD)

Centro de Investigación en Matemáticas Unidad Monterrey, Apodaca 66628, NL, Mexico.
Consejo Nacional de Humanidades, Ciencias y Tecnologías, Ciudad de Mexico 03940, Mexico.
ORCID: 0000-0001-6436-6755

Yelko Rodríguez-Carrasco (Y)

Research Group in Alternative Methods for Determining Toxics Effects and Risk Assessment of Contaminants and Mixtures (RiskTox), Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av. Vicent Andrés Estellés s/n, 46100 Valencia, Spain.
ORCID: 0000-0002-6421-218X

María-José Ruiz (MJ)

Research Group in Alternative Methods for Determining Toxics Effects and Risk Assessment of Contaminants and Mixtures (RiskTox), Laboratory of Food Chemistry and Toxicology, Faculty of Pharmacy, University of Valencia, Av. Vicent Andrés Estellés s/n, 46100 Valencia, Spain.
ORCID: 0000-0003-4174-6688

Gulnaz Stybayeva (G)

Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55901, USA.
ORCID: 0000-0002-1453-245X

Alexander Revzin (A)

Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55901, USA.

Jose M de Hoyos-Vega (JM)

Department of Physiology and Biomedical Engineering, Mayo Clinic, Rochester, MN 55901, USA.
ORCID: 0000-0001-7537-1090

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Classifications MeSH

questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Mycotoxines › Trichothécènes › Trichothécènes de type A › Toxine T-2 › Using Microfluidic Hepatic Spheroid Cultures...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Using Microfluidic Hepatic Spheroid Cultures...
questionsmedicales.fr › Cellules › Cellules épithéliales › Hépatocytes › Cellules HepG2 › Using Microfluidic Hepatic Spheroid Cultures...
questionsmedicales.fr › Cellules › Cellules cultivées › Sphéroïdes de cellules › Using Microfluidic Hepatic Spheroid Cultures...
questionsmedicales.fr › Système digestif › Foie › Using Microfluidic Hepatic Spheroid Cultures...
questionsmedicales.fr › Techniques d'investigation › Techniques in vitro › Techniques de culture › Techniques de coculture › Using Microfluidic Hepatic Spheroid Cultures...
questionsmedicales.fr › Technologie, industrie et agriculture › Technologie › Miniaturisation › Microtechnologie › Microfluidique › Using Microfluidic Hepatic Spheroid Cultures...
questionsmedicales.fr › Cellules › Cellules épithéliales › Hépatocytes › Using Microfluidic Hepatic Spheroid Cultures...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Survie cellulaire › Using Microfluidic Hepatic Spheroid Cultures...