Multistationarity questions in reduced versus extended biochemical networks.
Chemical reaction networks
ERK pathway
MESSI systems
Multistationarity
Journal
Journal of mathematical biology
ISSN: 1432-1416
Titre abrégé: J Math Biol
Pays: Germany
ID NLM: 7502105
Informations de publication
Date de publication:
24 Jun 2024
24 Jun 2024
Historique:
received:
19
10
2023
accepted:
30
05
2024
revised:
23
05
2024
medline:
25
6
2024
pubmed:
25
6
2024
entrez:
24
6
2024
Statut:
epublish
Résumé
We address several questions in reduced versus extended networks via the elimination or addition of intermediate complexes in the framework of chemical reaction networks with mass-action kinetics. We clarify and extend advances in the literature concerning multistationarity in this context, mainly from Feliu and Wiuf (J R Soc Interface 10:20130484, 2013), Sadeghimanesh and Feliu (Bull Math Biol 81:2428-2462, 2019), Pérez Millán and Dickenstein (SIAM J Appl Dyn Syst 17(2):1650-1682, 2018), Dickenstein et al. (Bull Math Biol 81:1527-1581, 2019). We establish general results about MESSI systems, which we use to compute the circuits of multistationarity for significant biochemical networks.
Identifiants
pubmed: 38914780
doi: 10.1007/s00285-024-02115-7
pii: 10.1007/s00285-024-02115-7
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
18Subventions
Organisme : FAPEMIG
ID : RED-00133-21
Organisme : UBACYT
ID : 20020220200166BA
Organisme : UBACYT
ID : 20020220200166BA
Organisme : CONICET PIP
ID : 11220200100182CO
Organisme : CONICET PIP
ID : 11220200100182CO
Organisme : CONICET PIP
ID : 11220200100182CO
Informations de copyright
© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
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