[Glucose metabolism disorders and hypoglycemic therapy in patients hospitalized for elective lower limb arthroplasty: a prospective, single-center, real-world study].

To assess the incidence of glucose metabolism disorders, administered hypoglycemic therapy and its effectiveness in a cohort of patients with previously diagnosed diabetes mellitus (DM) hospitalized for scheduled lower limb joint arthroplasty. The study included 502 patients. Medical history, information about previously diagnosed DM and prescribed hypoglycemic therapy were collected in all patients according to medical documentation, as well as according to the patients' survey. Within the preoperative examination, the glucose level was measured, and in patients with previously diagnosed diabetes, measuremaent of the HbA The study population included 180 (35.9%) males and 322 females (64.1%). Among them, 99 (19.7%) patients had disorders of glucose metabolism [type 1 diabetes - 1 (0.2%) patient, type 2 diabetes - 90 (17.9%) patients, impaired glucose tolerance (IGT) - 8 (1.6%) patients]. In 8 patients, type 2 diabetes was newly diagnosed during the preoperative examination. HbA The cohort of patients hospitalized for elective lower limb joint arthroplasty is characterized by a relatively high incidence of glucose metabolism disorders, and in some patients, DM was newly diagnosed during the preoperative examination. Metformin is most often used as hypoglycemic therapy, and the target values of glycemia during treatment were achieved in less than half of the patients. The monitoring of the level of glycated hemoglobin is low and requires additional population analysis in order to determine the causes and optimize the strategy of patient management. Цель. Изучить выявляемость нарушений метаболизма глюкозы, назначенную сахароснижающую терапию и ее эффективность в когорте пациентов с ранее диагностированным сахарным диабетом (СД), госпитализированных для планового эндопротезирования суставов нижних конечностей. Материалы и методы. В одноцентровое когортное проспективное исследование включены 502 пациента, у которых собирали анамнез заболевания, сведения о ранее диагностированном СД и назначенной сахароснижающей терапии по данным медицинской документации, а также со слов самих пациентов. В рамках предоперационного обследования измерен уровень глюкозы в венозной крови, а при наличии ранее диагностированного СД рекомендовалось измерить уровень гликированного гемоглобина (HbA