The possible cardioprotective effect of ghrelin during experimental endotoxemia in mice.
Animals
Mice
Male
Ghrelin
/ blood
Endotoxemia
/ blood
Cardiotonic Agents
/ pharmacology
Tumor Necrosis Factor-alpha
/ blood
Toll-Like Receptor 4
/ metabolism
Disease Models, Animal
Dinoprost
/ analogs & derivatives
Macrophage Migration-Inhibitory Factors
/ blood
Sepsis
/ drug therapy
Antioxidants
/ pharmacology
8-epi-PGF2α
CLP
MIF
TLR4
TNF-α
cardiac
ghrelin
sepsis
Journal
Journal of medicine and life
ISSN: 1844-3117
Titre abrégé: J Med Life
Pays: Romania
ID NLM: 101477617
Informations de publication
Date de publication:
May 2024
May 2024
Historique:
received:
15
07
2023
accepted:
04
10
2023
medline:
15
8
2024
pubmed:
15
8
2024
entrez:
15
8
2024
Statut:
ppublish
Résumé
This study aimed to evaluate the cardioprotective effects of ghrelin in septic mice, focusing on its anti-inflammatory and antioxidant properties. Thirty-five male Swiss mice (8-12 weeks old, 23-33g) were randomly assigned to five groups (
Identifiants
pubmed: 39144689
doi: 10.25122/jml-2023-0228
pii: JMedLife-17-486
pmc: PMC11320619
doi:
Substances chimiques
Ghrelin
0
Cardiotonic Agents
0
Tumor Necrosis Factor-alpha
0
8-epi-prostaglandin F2alpha
27415-26-5
Toll-Like Receptor 4
0
Dinoprost
B7IN85G1HY
Macrophage Migration-Inhibitory Factors
0
Antioxidants
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
486-491Informations de copyright
© 2024 by the authors.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.