High-level succinic acid production by overexpressing a magnesium transporter in

Succinic Acid / metabolism Magnesium / metabolism Fermentation Mannheimia / metabolism Metabolic Engineering / methods Bacterial Proteins / metabolism Cation Transport Proteins / metabolism
Mannheimia succiniciproducens fermentation magnesium transporter succinic acid sustainability

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
10 Sep 2024
Historique:
medline: 6 9 2024
pubmed: 6 9 2024
entrez: 6 9 2024
Statut: ppublish

Résumé

Succinic acid (SA), a dicarboxylic acid of industrial importance, can be efficiently produced by metabolically engineered

Identifiants

DOI: 10.1073/pnas.2407455121 PMID: 39240971
pubmed: 39240971
doi: 10.1073/pnas.2407455121
doi:

Substances chimiques

Succinic Acid AB6MNQ6J6L
Magnesium I38ZP9992A
Bacterial Proteins 0
Cation Transport Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2407455121

Subventions

Organisme : Ministry of Science and ICT, South Korea (MSIT)
ID : 2022M3J5A1056072
Organisme : Ministry of Science and ICT, South Korea (MSIT)
ID : 2022M3J5A1056117

Déclaration de conflit d'intérêts

Competing interests statement:Authors declare that they have competing financial interests as the

Auteurs

Ji Yeon Kim (JY)

Metabolic and Biomolecular Engineering National Research Laboratory and Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, Department of Chemical and Biomolecular Engineering (BK21 four), Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.
ORCID: 0000-0001-8040-0968

Jong An Lee (JA)

Metabolic and Biomolecular Engineering National Research Laboratory and Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, Department of Chemical and Biomolecular Engineering (BK21 four), Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.
BioInformatics Research Center and BioProcess Engineering Research Center, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.
ORCID: 0000-0001-6818-027X

Jung Ho Ahn (JH)

Metabolic and Biomolecular Engineering National Research Laboratory and Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, Department of Chemical and Biomolecular Engineering (BK21 four), Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.
ORCID: 0000-0002-3543-8446

Sang Yup Lee (SY)

Metabolic and Biomolecular Engineering National Research Laboratory and Systems Metabolic Engineering and Systems Healthcare Cross-Generation Collaborative Laboratory, Department of Chemical and Biomolecular Engineering (BK21 four), Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.
BioInformatics Research Center and BioProcess Engineering Research Center, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.
Graduate School of Engineering Biology, Korea Advanced Institute of Science and Technology, Daejeon 34141, Republic of Korea.
ORCID: 0000-0003-0599-3091

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Classifications MeSH

questionsmedicales.fr › Composés chimiques organiques › Acides carboxyliques › Acides acycliques › Diacides carboxyliques › Succinates › Acide succinique › High-level succinic acid production by...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux légers › Magnésium › High-level succinic acid production by...
questionsmedicales.fr › Métabolisme › Métabolisme glucidique › Fermentation › High-level succinic acid production by...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Pasteurellaceae › Mannheimia › High-level succinic acid production by...
questionsmedicales.fr › Technologie, industrie et agriculture › Ingénierie › Bioingénierie › Ingénierie cellulaire › Génie métabolique › High-level succinic acid production by...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines bactériennes › High-level succinic acid production by...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Protéines de transport membranaire › Pompes ioniques › Transporteurs de cations › High-level succinic acid production by...