The effect of parental pain, disability benefits and education on risk of long-term sick leave due to musculoskeletal disorders and the modifying effect of sleep and physical activity: the HUNT study.
Humans
Sick Leave
/ statistics & numerical data
Male
Female
Norway
/ epidemiology
Musculoskeletal Diseases
/ epidemiology
Adult
Adolescent
Prospective Studies
Young Adult
Parents
/ psychology
Educational Status
Chronic Pain
/ epidemiology
Sleep Wake Disorders
/ epidemiology
Risk Factors
Sleep
Exercise
Insurance, Disability
/ statistics & numerical data
Motor Activity
Cohort study
Family factors
Musculoskeletal disorders
Physical activity
Sick leave
Sleep
Work disability
Young adults
Journal
BMC public health
ISSN: 1471-2458
Titre abrégé: BMC Public Health
Pays: England
ID NLM: 100968562
Informations de publication
Date de publication:
27 Sep 2024
27 Sep 2024
Historique:
received:
10
11
2023
accepted:
12
09
2024
medline:
28
9
2024
pubmed:
28
9
2024
entrez:
28
9
2024
Statut:
epublish
Résumé
Family factors, sleep, and physical activity have previously been associated with risk of sick leave and disability benefits due to musculoskeletal disorders. However, how these factors act during adolescence and young adulthood is unclear. The aim of this study was to (i) examine if chronic pain, disability benefits and education in parents influence the risk of long-term sick leave due to musculoskeletal disorders in young adulthood, and (ii) to explore if offspring sleep problems and physical activity modify these effects. A population-based prospective study of 18,552 adolescents and young adults (≤ 30 years) in the Norwegian HUNT Study. Survey data was linked to national registry data on sick leave, disability benefits, family relations and educational attainment. We used Cox regression to estimate hazard ratio (HR) with 95% confidence interval (CI) for long-term (≥ 31 days) sick leave due to a musculoskeletal disorder in offspring associated with parental factors and the joint effect of parental factors and offspring lifestyle factors. Parental chronic pain (HR 1.36, 95% CI 1.27-1.45), disability benefits (HR 1.41, 95% CI 1.33-1.48) and low educational attainment (HR 1.78, 95% CI 1.67-1.90) increased the risk of long-term sick leave due to musculoskeletal disorders among offspring. There was no strong evidence that sleep and physical activity modified these effects. Chronic pain, disability benefit and low education in parents increased the risk of long-term sick leave due to musculoskeletal disorders among offspring, but these effects were not modified by offspring sleep problems or physical activity level. The findings suggest that efforts beyond individual lifestyle factors might be important as preventive measures.
Sections du résumé
BACKGROUND
BACKGROUND
Family factors, sleep, and physical activity have previously been associated with risk of sick leave and disability benefits due to musculoskeletal disorders. However, how these factors act during adolescence and young adulthood is unclear. The aim of this study was to (i) examine if chronic pain, disability benefits and education in parents influence the risk of long-term sick leave due to musculoskeletal disorders in young adulthood, and (ii) to explore if offspring sleep problems and physical activity modify these effects.
METHODS
METHODS
A population-based prospective study of 18,552 adolescents and young adults (≤ 30 years) in the Norwegian HUNT Study. Survey data was linked to national registry data on sick leave, disability benefits, family relations and educational attainment. We used Cox regression to estimate hazard ratio (HR) with 95% confidence interval (CI) for long-term (≥ 31 days) sick leave due to a musculoskeletal disorder in offspring associated with parental factors and the joint effect of parental factors and offspring lifestyle factors.
RESULTS
RESULTS
Parental chronic pain (HR 1.36, 95% CI 1.27-1.45), disability benefits (HR 1.41, 95% CI 1.33-1.48) and low educational attainment (HR 1.78, 95% CI 1.67-1.90) increased the risk of long-term sick leave due to musculoskeletal disorders among offspring. There was no strong evidence that sleep and physical activity modified these effects.
CONCLUSION
CONCLUSIONS
Chronic pain, disability benefit and low education in parents increased the risk of long-term sick leave due to musculoskeletal disorders among offspring, but these effects were not modified by offspring sleep problems or physical activity level. The findings suggest that efforts beyond individual lifestyle factors might be important as preventive measures.
Identifiants
pubmed: 39334159
doi: 10.1186/s12889-024-20071-1
pii: 10.1186/s12889-024-20071-1
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2617Informations de copyright
© 2024. The Author(s).
Références
Bevan S. Economic impact of musculoskeletal disorders (MSDs) on work in Europe. Best Pract Res Clin Rheumatol. 2015;29(3):356–73.
doi: 10.1016/j.berh.2015.08.002
pubmed: 26612235
Brage S, Ihlebaek C, Natvig B, Bruusgaard D. Musculoskeletal disorders as causes of sick leave and disability benefits. Tidsskrift den Norske Laegeforening: Tidsskrift Praktisk Medicin ny Raekke. 2010;130(23):2369–70.
doi: 10.4045/tidsskr.10.0236
OECD. Sickness, disability and work: Breaking the barriers: Organisation for Economic Co-operation and Development; 2010.
Waddell G, Burton AK. Is work good for your health and well-being? 2006.
European Agency for Safety and Health at Work, Schmidt K, Friedrichs P, Cornelsen H, Schmidt P, Tischer T. Musculoskeletal disorders among children and young people – prevalence, risk factors and preventive measures – A scoping review. Publications Office of the European Union; 2021.
Mundal A. Flest til fastlegen på grunn av muskel-og skjelettlidelser. 2018.
Vos T, Allen C, Arora M, Barber RM, Bhutta ZA, Brown A, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the global burden of Disease Study 2015. Lancet. 2016;388(10053):1545–602.
doi: 10.1016/S0140-6736(16)31678-6
Gravseth HM, Bjerkedal T, Irgens LM, Aalen OO, Selmer R, Kristensen P. Life course determinants for early disability pension: a follow-up of Norwegian men and women born 1967–1976. Eur J Epidemiol. 2007;22(8):533–43.
doi: 10.1007/s10654-007-9139-9
pubmed: 17530421
Harkonmäki K, Silventoinen K, Levälahti E, Pitkäniemi J, Huunan-Seppälä A, Klaukka T, et al. The genetic liability to disability retirement: a 30-year follow-up study of 24,000 Finnish twins. PLoS ONE. 2008;3(10):e3402.
doi: 10.1371/journal.pone.0003402
pubmed: 18923678
pmcid: 2566596
Narusyte J, Ropponen A, Silventoinen K, Alexanderson K, Kaprio J, Samuelsson Å, et al. Genetic liability to disability pension in women and men: a prospective population-based twin study. PLoS ONE. 2011;6(8):e23143.
doi: 10.1371/journal.pone.0023143
pubmed: 21850258
pmcid: 3151284
Young EE, Lariviere WR, Belfer I. Genetic basis of pain variability: recent advances. J Med Genet. 2012;49(1):1.
doi: 10.1136/jmedgenet-2011-100386
pubmed: 22058430
Hartvigsen J, Nielsen J, Kyvik KO, Fejer R, Vach W, Iachine I, et al. Heritability of spinal pain and consequences of spinal pain: a comprehensive genetic epidemiologic analysis using a population-based sample of 15,328 twins ages 20–71 years. Arthritis Care Res (Hoboken). 2009;61(10):1343–51.
doi: 10.1002/art.24607
Kerr JI, Burri A. Genetic and epigenetic epidemiology of chronic widespread pain. J Pain Res. 2017;10:2021–9.
doi: 10.2147/JPR.S143869
pubmed: 28894385
pmcid: 5584918
Gjerde LC, Knudsen GP, Czajkowski N, Gillespie N, Aggen SH, Røysamb E, et al. Genetic and environmental contributions to long-term sick leave and disability pension: a Population-based study of young adult Norwegian twins. Twin Res Hum Genet. 2013;16(4):759–66.
doi: 10.1017/thg.2013.36
pubmed: 23743022
pmcid: 3800163
Svedberg P, Ropponen A, Alexanderson K, Lichtenstein P, Narusyte J. Genetic susceptibility to sickness absence is similar among women and men: findings from a Swedish twin cohort. Twin Res Hum Genet. 2012;15(5):642–8.
doi: 10.1017/thg.2012.47
pubmed: 22931554
Lynch J, Smith GD, A LIFE COURSE APPROACH, TO CHRONIC DISEASE EPIDEMIOLOGY. Annu Rev Public Health. 2005;26(1):1–35.
doi: 10.1146/annurev.publhealth.26.021304.144505
pubmed: 15760279
Ben-Shlomo Y, Kuh D. A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives. Int J Epidemiol. 2002;31(2):285–93.
doi: 10.1093/ije/31.2.285
pubmed: 11980781
Lahti J, Laaksonen M, Lahelma E, Rahkonen O. The impact of physical activity on sickness absence. Scand J Med Sci Sports. 2010;20(2):191–9.
doi: 10.1111/j.1600-0838.2009.00886.x
pubmed: 19486485
Amiri S, Behnezhad S. Sleep disturbances and risk of sick leave: systematic review and meta-analysis. Sleep Biol Rhythms. 2020;18(4):283–95.
doi: 10.1007/s41105-020-00270-0
Haaramo P, Rahkonen O, Lahelma E, Lallukka T. The joint association of sleep duration and insomnia symptoms with disability retirement - a longitudinal, register-linked study. Scandinavian J Work Environ Health. 2012;38(5):427–35.
doi: 10.5271/sjweh.3269
Karkkainen S, Ropponen A, Narusyte J, Mather L, Akerstedt T, Silventoinen K, et al. Night work as a risk factor of future disability pension due to musculoskeletal diagnoses: a prospective cohort study of Swedish twins. Eur J Pub Health. 2017;27(4):659–64.
doi: 10.1093/eurpub/ckx084
Ropponen A, Silventoinen K, Hublin C, Svedberg P, Koskenvuo M, Kaprio J. Sleep patterns as predictors for disability pension due to low back diagnoses: a 23-year longitudinal study of Finnish twins. Sleep. 2013;36(6):891–7.
doi: 10.5665/sleep.2718
pubmed: 23729932
pmcid: 3649831
Lallukka T, Haaramo P, Lahelma E, Rahkonen O. Sleep problems and disability retirement: a register-based follow-up study. Am J Epidemiol. 2011;173(8):871–81.
doi: 10.1093/aje/kwq462
pubmed: 21415034
Holtermann A, Hansen JV, Burr H, Søgaard K, Sjøgaard G. The health paradox of occupational and leisure-time physical activity. Br J Sports Med. 2012;46(4):291–5.
doi: 10.1136/bjsm.2010.079582
pubmed: 21459873
Kerner I, Rakovac M, Lazinica B. Leisure-time physical activity and absenteeism. Archives Industrial Hygiene Toxicol. 2017;68(3):159–70.
doi: 10.1515/aiht-2017-68-2963
Proper KI, van den Heuvel SG, De Vroome EM, Hildebrandt VH, Van der Beek AJ. Dose–response relation between physical activity and sick leave. Br J Sports Med. 2006;40(2):173–8.
doi: 10.1136/bjsm.2005.022327
pubmed: 16432007
pmcid: 2492021
van Amelsvoort LG, Spigt MG, Swaen GM, Kant I. Leisure time physical activity and sickness absenteeism; a prospective study. Occup Med (Lond). 2006;56(3):210–2.
doi: 10.1093/occmed/kqj026
pubmed: 16641504
Fimland MS, Vie G, Johnsen R, Nilsen TIL, Krokstad S, Bjørngaard JH. Leisure-time physical activity and disability pension: 9 years follow-up of the HUNT study, Norway. Scand J Med Sci Sports. 2015;25(6):e558–65.
doi: 10.1111/sms.12369
pubmed: 25487654
Krokstad S, Langhammer A, Hveem K, Holmen T, Midthjell K, Stene T, et al. Cohort profile: the HUNT study, Norway. Int J Epidemiol. 2013;42(4):968–77.
doi: 10.1093/ije/dys095
pubmed: 22879362
Holmen TL, Bratberg G, Krokstad S, Langhammer A, Hveem K, Midthjell K, et al. Cohort profile of the Young-HUNT Study, Norway: a population-based study of adolescents. Int J Epidemiol. 2013;43(2):536–44.
doi: 10.1093/ije/dys232
pubmed: 23382364
Vandenbroucke JP, von Elm E, Altman DG, Gøtzsche PC, Mulrow CD, Pocock SJ, et al. Strengthening the reporting of Observational studies in Epidemiology (STROBE): explanation and elaboration. Epidemiology. 2007;18(6):805–35.
doi: 10.1097/EDE.0b013e3181577511
pubmed: 18049195
Cole TJ, Lobstein T. Extended international (IOTF) body mass index cut-offs for thinness, overweight and obesity. Pediatr Obes. 2012;7(4):284–94.
doi: 10.1111/j.2047-6310.2012.00064.x
pubmed: 22715120
Andersson T, Alfredsson L, Källberg H, Zdravkovic S, Ahlbom A. Calculating measures of biological interaction. Eur J Epidemiol. 2005;20(7):575–9.
doi: 10.1007/s10654-005-7835-x
pubmed: 16119429
StataCorp. Stata Statistical Software: Release 17 [Software]. College Station, TX: StataCorp LLC; 2021 [ https://www.stata.com/
Lier R, Mork PJ, Holtermann A, Nilsen TIL. Familial risk of chronic musculoskeletal pain and the importance of physical activity and body mass index: prospective data from the HUNT study, Norway. PLoS ONE. 2016;11(4):e0153828.
doi: 10.1371/journal.pone.0153828
pubmed: 27082110
pmcid: 4833298
Zadro J, Nilsen T, Shirley D, Amorim A, Ferreira P, Mork P. Parental chronic widespread pain and the association with chronic widespread pain in adult offspring: family-linkage data from the Norwegian HUNT study. Eur J Pain. 2018;22(8):1485–93.
doi: 10.1002/ejp.1237
Pape K, Bjørngaard JH, De Ridder KA, Westin S, Holmen TL, Krokstad S. Medical benefits in young norwegians and their parents, and the contribution of family health and socioeconomic status. The HUNT study, Norway. Scand J Public Health. 2013;41(5):455–62.
doi: 10.1177/1403494813481645
pubmed: 23508948
Lantz PM, House JS, Lepkowski JM, Williams DR, Mero RP, Chen J. Socioeconomic factors, health behaviors, and mortality: results from a nationally representative prospective study of US adults. JAMA. 1998;279(21):1703–8.
doi: 10.1001/jama.279.21.1703
pubmed: 9624022
Zhang YB, Chen C, Pan XF, Guo J, Li Y, Franco OH, et al. Associations of healthy lifestyle and socioeconomic status with mortality and incident cardiovascular disease: two prospective cohort studies. BMJ. 2021;373:n604.
doi: 10.1136/bmj.n604
pubmed: 33853828
pmcid: 8044922
Sorensen G, Emmons K, Hunt MK, Barbeau E, Goldman R, Peterson K, et al. Model for incorporating social context in health behavior interventions: applications for cancer prevention for working-class, multiethnic populations. Prev Med. 2003;37(3):188–97.
doi: 10.1016/S0091-7435(03)00111-7
pubmed: 12914824
Skarpsno ES, Mork PJ, Hagen K, Nilsen TIL, Marcuzzi A. Number of chronic Nighttime insomnia symptoms and risk of chronic widespread Pain and Pain-Related disability: the HUNT study. Nat Sci Sleep. 2020;12:1227–36.
doi: 10.2147/NSS.S284498
pubmed: 33402855
pmcid: 7778442
Wiklund T, Gerdle B, Linton SJ, Dragioti E, Larsson B. Insomnia is a risk factor for spreading of chronic pain: a Swedish longitudinal population study (SwePain). Eur J Pain. 2020;24(7):1348–56.
doi: 10.1002/ejp.1582
pubmed: 32386443
Shephard RJ. Limits to the measurement of habitual physical activity by questionnaires. Br J Sports Med. 2003;37(3):197.
doi: 10.1136/bjsm.37.3.197
pubmed: 12782543
pmcid: 1724653
Amiri S. Body mass index and sleep disturbances: a systematic review and meta-analysis. Postep Psychiatr Neurol. 2023;32(2):96–109.
pubmed: 37497197
pmcid: 10367528