Pathway and Production Differences in Branched-Chain Hydroxy Acids as Bioactive Metabolites in
2-hydroxy isocaproic acid (HICA)
2-hydroxy isovaleric acid (HIVA)
2-hydroxy-3-methyl valeric acid (HMVA)
Lactobacillaceae
bioactive metabolites
metabolomics
probiotics
Journal
International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791
Informations de publication
Date de publication:
20 Sep 2024
20 Sep 2024
Historique:
received:
28
08
2024
revised:
19
09
2024
accepted:
19
09
2024
medline:
28
9
2024
pubmed:
28
9
2024
entrez:
28
9
2024
Statut:
epublish
Résumé
Branched-chain hydroxy acids (BCHAs) as bioactive metabolites of Lactobacillaceae include 2-hydroxy isovaleric acid (HIVA), 2-hydroxy isocaproic acid (HICA), and 2-hydroxy-3-methyl isovaleric acid (HMVA). Combining targeted and untargeted metabolomics, this study elucidates differences in extracellular BCHA production in
Identifiants
pubmed: 39337595
pii: ijms251810112
doi: 10.3390/ijms251810112
pii:
doi:
Substances chimiques
Hydroxy Acids
0
Amino Acids, Branched-Chain
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM