Bacillus subtilis EpsA-O: A novel exopolysaccharide structure acting as an efficient adhesive in biofilms.
Journal
NPJ biofilms and microbiomes
ISSN: 2055-5008
Titre abrégé: NPJ Biofilms Microbiomes
Pays: United States
ID NLM: 101666944
Informations de publication
Date de publication:
02 Oct 2024
02 Oct 2024
Historique:
received:
24
01
2024
accepted:
20
08
2024
medline:
3
10
2024
pubmed:
3
10
2024
entrez:
2
10
2024
Statut:
epublish
Résumé
Extracellular polysaccharides are crucial components for biofilm development. Although Bacillus subtilis is one of the most characterized Gram-positive biofilm model system, the structure-function of its exopolysaccharide, EpsA-O, remains to be elucidated. By combining chemical analysis, NMR spectroscopy, rheology, and molecular modeling, high-resolution data of EpsA-O structure from atom to supramolecular scale was obtained. The repeating unit is composed of the trisaccharide backbone [→3)-β-D-QuipNAc4NAc-(1→3)-β-D-GalpNAc-(1→3)-α-D-GlcpNAc-(1]
Identifiants
pubmed: 39358392
doi: 10.1038/s41522-024-00555-z
pii: 10.1038/s41522-024-00555-z
doi:
Substances chimiques
Polysaccharides, Bacterial
0
exopolysaccharide, Bacillus
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
98Subventions
Organisme : The Slovenian Research and Innovation Agency (ARIS)
ID : J1-3021
Organisme : The Slovenian Research and Innovation Agency (ARIS)
ID : MRIC UL, I0-0022-0481-08
Organisme : The Slovenian Research and Innovation Agency (ARIS)
ID : MRIC UL, I0-0022-0481-08
Organisme : The Slovenian Research and Innovation Agency (ARIS)
ID : J1-3021
Organisme : The Slovenian Research and Innovation Agency (ARIS)
ID : J1-3021
Organisme : The Slovenian Research and Innovation Agency (ARIS)
ID : MRIC UL, I0-0022-0481-08
Informations de copyright
© 2024. The Author(s).
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