Intestinal

Animals Gastrointestinal Microbiome Polyamines / metabolism Mice Lactobacillus / metabolism Humans Swine Colitis / metabolism Colorectal Neoplasms / metabolism Dextran Sulfate Colon / metabolism Extracellular Vesicles / metabolism
CRC Lactobacillus murinus colitis polyamine metabolism small RNAs

Journal

Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876

Informations de publication

Date de publication:
08 Oct 2024
Historique:
medline: 4 10 2024
pubmed: 4 10 2024
entrez: 3 10 2024
Statut: ppublish

Résumé

Gut microbiota plays a vital role in host metabolism; however, the influence of gut microbes on polyamine metabolism is unknown. Here, we found germ-free models possess elevated polyamine levels in the colon. Mechanistically, intestinal

Identifiants

DOI: 10.1073/pnas.2413241121 PMID: 39361652
pubmed: 39361652
doi: 10.1073/pnas.2413241121
doi:

Substances chimiques

Polyamines 0
Dextran Sulfate 9042-14-2

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2413241121

Subventions

Organisme : National natural science foundation of china
ID : U22A20510 32225047 32072687
Organisme : Double first-class discipline promotion project
ID : 2023B10564001
Organisme : National center of technology innovation for pigs
ID : NCTIP-XD/B13

Déclaration de conflit d'intérêts

Competing interests statement:The authors declare no competing interest.

Auteurs

Lijuan Fan (L)

State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
National Center of Technology Innovation for Pigs, Chongqing 402460, China.

Bingnan Liu (B)

State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
National Center of Technology Innovation for Pigs, Chongqing 402460, China.

Youxia Wang (Y)

State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
National Center of Technology Innovation for Pigs, Chongqing 402460, China.

Bin Tang (B)

Department of Clinical Laboratory, Chongqing University Jiangjin Hospital, School of Medicine, Chongqing University, Jiangjin, Chongqing 402260, China.

Tianqi Xu (T)

Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.

Jian Fu (J)

State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
National Center of Technology Innovation for Pigs, Chongqing 402460, China.

Chuanlong Wang (C)

State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
National Center of Technology Innovation for Pigs, Chongqing 402460, China.

Yuan Liu (Y)

Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Institute of Comparative Medicine, College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
ORCID: 0000-0002-9622-6471

Liangpeng Ge (L)

National Center of Technology Innovation for Pigs, Chongqing Academy of Animal Sciences, Key Laboratory of Pig Industry Science, Ministry of Agriculture, Chongqing 402460, China.

Hong Wei (H)

State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan 430070, China.

Wenkai Ren (W)

State Key Laboratory of Swine and Poultry Breeding Industry, College of Animal Science, South China Agricultural University, Guangzhou 510642, China.
National Center of Technology Innovation for Pigs, Chongqing 402460, China.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Intestinal
questionsmedicales.fr › Environnement et santé publique › Environnement › Écosystème › Biodiversité › Biote › Microbiote › Microbiome gastro-intestinal › Intestinal
questionsmedicales.fr › Composés chimiques organiques › Amines › Polyamines › Intestinal
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Intestinal
questionsmedicales.fr › Bactéries › Bactéries à Gram positif › Lactobacillales › Lactobacillaceae › Lactobacillus › Intestinal
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Intestinal
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Suidae › Intestinal
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies du côlon › Colite › Intestinal
questionsmedicales.fr › Maladies de l'appareil digestif › Maladies gastro-intestinales › Maladies intestinales › Maladies du rectum › Tumeurs colorectales › Intestinal
questionsmedicales.fr › Glucides › Polyosides › Glucanes › Dextrane › Sulfate dextran › Intestinal
questionsmedicales.fr › Système digestif › Tube digestif › Tube digestif inférieur › Gros intestin › Côlon › Intestinal
questionsmedicales.fr › Cellules › Structures cellulaires › Espace extracellulaire › Vésicules extracellulaires › Intestinal