Elucidation of Spartina dimethylsulfoniopropionate synthesis genes enables engineering of stress tolerant plants.
Journal
Nature communications
ISSN: 2041-1723
Titre abrégé: Nat Commun
Pays: England
ID NLM: 101528555
Informations de publication
Date de publication:
09 Oct 2024
09 Oct 2024
Historique:
received:
01
12
2023
accepted:
16
08
2024
medline:
10
10
2024
pubmed:
10
10
2024
entrez:
9
10
2024
Statut:
epublish
Résumé
The organosulfur compound dimethylsulfoniopropionate (DMSP) has key roles in stress protection, global carbon and sulfur cycling, chemotaxis, and is a major source of climate-active gases. Saltmarshes are global hotspots for DMSP cycling due to Spartina cordgrasses that produce exceptionally high concentrations of DMSP. Here, in Spartina anglica, we identify the plant genes that underpin high-level DMSP synthesis: methionine S-methyltransferase (MMT), S-methylmethionine decarboxylase (SDC) and DMSP-amine oxidase (DOX). Homologs of these enzymes are common in plants, but differences in expression and catalytic efficiency explain why S. anglica accumulates such high DMSP concentrations and other plants only accumulate low concentrations. Furthermore, DMSP accumulation in S. anglica is consistent with DMSP having a role in oxidative and osmotic stress protection. Importantly, administration of DMSP by root uptake or over-expression of Spartina DMSP synthesis genes confers plant tolerance to salinity and drought offering a route for future bioengineering for sustainable crop production.
Identifiants
pubmed: 39384757
doi: 10.1038/s41467-024-51758-z
pii: 10.1038/s41467-024-51758-z
doi:
Substances chimiques
Sulfonium Compounds
0
dimethylpropiothetin
C884XA7QGG
Plant Proteins
0
Methyltransferases
EC 2.1.1.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
8568Subventions
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : NE/V000756/1
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : NE/V000756/1
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : NE/V000756/1
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : NE/S007334/1
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : MR/T044020/1
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : NE/V000756/1
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : NE/V000756/1
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : NE/P012671
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : NE/S001352
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : NE/X000990
Organisme : RCUK | Natural Environment Research Council (NERC)
ID : NE/X014428
Organisme : RCUK | Biotechnology and Biological Sciences Research Council (BBSRC)
ID : BB/X005968/1
Organisme : RCUK | Biotechnology and Biological Sciences Research Council (BBSRC)
ID : BB/X005968/1
Organisme : RCUK | Biotechnology and Biological Sciences Research Council (BBSRC)
ID : BB/X005968/1
Organisme : RCUK | Biotechnology and Biological Sciences Research Council (BBSRC)
ID : BB/T008717/1
Organisme : RCUK | Biotechnology and Biological Sciences Research Council (BBSRC)
ID : BB/T008717/1
Organisme : RCUK | Biotechnology and Biological Sciences Research Council (BBSRC)
ID : BB/X005968/1
Organisme : Leverhulme Trust
ID : RPG-2020-413
Informations de copyright
© 2024. The Author(s).
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