Monoamine Oxidase Contributes to Valvular Oxidative Stress: A Prospective Observational Pilot Study in Patients with Severe Mitral Regurgitation.

Humans Oxidative Stress Mitral Valve Insufficiency / metabolism Male Female Pilot Projects Monoamine Oxidase / metabolism Middle Aged Prospective Studies Aged Reactive Oxygen Species / metabolism Hydrogen Peroxide / metabolism Mitral Valve / metabolism Angiotensin II / metabolism Echocardiography
MAO inhibitors (MAOI) angiotensin 2 angiotensin receptor blocker (ARB) monoamine oxidase (MAO) reactive oxygen species (ROS) severe mitral regurgitation

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
25 Sep 2024
Historique:
received: 22 07 2024
revised: 09 09 2024
accepted: 20 09 2024
medline: 16 10 2024
pubmed: 16 10 2024
entrez: 16 10 2024
Statut: epublish

Résumé

Monoamine oxidases (MAOs), mitochondrial enzymes that constantly produce hydrogen peroxide (H

Identifiants

DOI: 10.3390/ijms251910307 PMID: 39408637
pubmed: 39408637
pii: ijms251910307
doi: 10.3390/ijms251910307
pii:
doi:

Substances chimiques

Monoamine Oxidase EC 1.4.3.4
Reactive Oxygen Species 0
Hydrogen Peroxide BBX060AN9V
Angiotensin II 11128-99-7

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Auteurs

Raluca Șoșdean (R)

Department VI-Cardiology, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
Research Centre of the Institute of Cardiovascular Diseases, G. Adam Str. no 13A, 300310 Timișoara, Romania.
ORCID: 0000-0001-5998-2932

Maria D Dănilă (MD)

Department III-Pathophysiology, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
Centre for Translational Research and Systems Medicine, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
ORCID: 0000-0003-3700-8228

Loredana N Ionică (LN)

Centre for Translational Research and Systems Medicine, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
Department X-Medical Semiotics I, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.

Alexandru S Pescariu (AS)

Department VI-Cardiology, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
Research Centre of the Institute of Cardiovascular Diseases, G. Adam Str. no 13A, 300310 Timișoara, Romania.
ORCID: 0000-0002-1697-311X

Monica Mircea (M)

Research Centre of the Institute of Cardiovascular Diseases, G. Adam Str. no 13A, 300310 Timișoara, Romania.

Adina Ionac (A)

Department VI-Cardiology, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
Research Centre of the Institute of Cardiovascular Diseases, G. Adam Str. no 13A, 300310 Timișoara, Romania.
ORCID: 0000-0003-0635-8663

Cristian Mornoș (C)

Department VI-Cardiology, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
Research Centre of the Institute of Cardiovascular Diseases, G. Adam Str. no 13A, 300310 Timișoara, Romania.
ORCID: 0000-0002-6096-9601

Constantin T Luca (CT)

Department VI-Cardiology, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
Research Centre of the Institute of Cardiovascular Diseases, G. Adam Str. no 13A, 300310 Timișoara, Romania.

Horea B Feier (HB)

Research Centre of the Institute of Cardiovascular Diseases, G. Adam Str. no 13A, 300310 Timișoara, Romania.
Department VI-Cardiovascular Surgery, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Square no 2, 300041 Timișoara, Romania.
ORCID: 0000-0002-4870-8249

Danina M Muntean (DM)

Department III-Pathophysiology, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
Centre for Translational Research and Systems Medicine, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.

Adrian Sturza (A)

Department III-Pathophysiology, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
Centre for Translational Research and Systems Medicine, "Victor Babeș" University of Medicine and Pharmacy of Timișoara, E. Murgu Sq. no 2, 300041 Timișoara, Romania.
"Pius Brinzeu" Emergency County Hospital, 300723 Timisoara, Romania.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Phénomènes physiologiques › Stress physiologique › Stress oxydatif › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Maladies cardiovasculaires › Cardiopathies › Valvulopathies › Insuffisance mitrale › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Projets pilotes › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Oxidoreductases acting on CH-NH2 group donors › Monoamine oxidase › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Adulte d'âge moyen › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études prospectives › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Espèces réactives de l'oxygène › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Composés chimiques organiques › Radicaux libres › Peroxydes › Peroxyde d'hydrogène › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Système cardiovasculaire › Coeur › Valves cardiaques › Valve atrioventriculaire gauche › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Facteurs biologiques › Médiateurs de l'inflammation › Autacoïdes › Angiotensines › Angiotensine-II › Monoamine Oxidase Contributes to Valvular...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic cardiovasculaire › Tests de la fonction cardiaque › Échocardiographie › Monoamine Oxidase Contributes to Valvular...