First Report on Salvia Sahendica Boiss & Buhs roots biocomponents characterization by GC-MS and HPLC and Antibacterial Potency.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
22 10 2024
Historique:
received: 24 08 2024
accepted: 16 10 2024
medline: 23 10 2024
pubmed: 23 10 2024
entrez: 22 10 2024
Statut: epublish

Résumé

Treatment of bacterial infections with antibiotic resistance is complicated. For this reason, new therapeutic methods are needed to control bacterial infections. Therefore, it is necessary to discover new antibiotics from medicinal plants that can destroy drug-resistant bacteria. Essential oils (EO) of some medicinal plants have antimicrobial effects and can be used as antimicrobial agents in the treatment of infections and food industries. The aim of this study was to determine the EO composition and antimicrobial effects of EO and polyphenols profile of Salvia Sahendica roots for the first time. Chemical compounds and antibacterial activity of EOs against Staphylococcus aureus and Bacillus cereus as gram-positive and Escherichia coli and Pseudomonas aeruginosa as gram- negative bacteria were evaluated using microtiter broth dilution method. Studied organs of S. sahendica showed significant diversity in terms of type and percentage of essential oil and polyphenol compounds. Overall, 44, 46, 42, and 45 compounds were identified in the essential oil of leaves, flowers, stems, and roots of this plant, which constituted 99.6, 99.3, 98.2, and 99.4% of total oil composition, respectively. The current study collectively demonstrated inhibitory effects ranged from strong (S. aureus) to low inhibition (P. aeruginosa). According to the HPLC result, the amounts of coumaric acid, chlorogenic acid, and gallic acid compounds in the root are higher than in other plant parts, which indicate that the root can be a suitable source for the production of these valuable polyphenol compounds. Due to the results, it is possible to hope for the application of EO from S. sahendica as natural antibacterial in the pharmaceutical and food industries.

Identifiants

pubmed: 39438657
doi: 10.1038/s41598-024-76679-1
pii: 10.1038/s41598-024-76679-1
doi:

Substances chimiques

Anti-Bacterial Agents 0
Oils, Volatile 0
Polyphenols 0
Plant Extracts 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

24916

Informations de copyright

© 2024. The Author(s).

Références

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Auteurs

Elnaz Nourozi (E)

Academic Center for Education, Culture, and Research (ACECR), West Azarbayjan Branch, Urmia, Iran.

Ahad Hedayati (A)

Academic Center for Education, Culture, and Research (ACECR), West Azarbayjan Branch, Urmia, Iran. ahedayati67@yahoo.com.
Medicinal Plants and Drugs Research Institute, Shahid Beheshti university, Tehran, Iran. ahedayati67@yahoo.com.
Academic Center for Education, Culture, and Research (ACECR), West Azarbayjan Branch, P.O. Box: 165, Urmia, Iran. ahedayati67@yahoo.com.

Mohammad Hossein Mirjalili (MH)

Medicinal Plants and Drugs Research Institute, Shahid Beheshti university, Tehran, Iran.

Hadi Madani (H)

Department of Horticulture, Faculty of Agriculture, Urmia University, Urmia, Iran.

Atousa Aliahmadi (A)

Medicinal Plants and Drugs Research Institute, Shahid Beheshti university, Tehran, Iran.

Ali Akbar Zahedi (AA)

Department of Horticulture, Faculty of Agriculture, Urmia University, Urmia, Iran.

Zahra Aslani (Z)

Department of Horticulture, Faculty of Agriculture, Urmia University, Urmia, Iran.

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