EF24, a Curcumin Analog, Reverses Interleukin-18-Induced miR-30a or miR-342-Dependent TRAF3IP2 Expression, RECK Suppression, and the Proinflammatory Phenotype of Human Aortic Smooth Muscle Cells.

Humans MicroRNAs / genetics GPI-Linked Proteins / metabolism Curcumin / pharmacology Aorta / drug effects Myocytes, Smooth Muscle / drug effects Interleukin-18 / metabolism Phenotype Adaptor Proteins, Signal Transducing / metabolism Inflammation / pathology Cells, Cultured
atherosclerosis cell proliferation curcumin inflammation migration vascular proliferative diseases

Journal

Cells
ISSN: 2073-4409
Titre abrégé: Cells
Pays: Switzerland
ID NLM: 101600052

Informations de publication

Date de publication:
10 Oct 2024
Historique:
received: 01 08 2024
revised: 24 09 2024
accepted: 03 10 2024
medline: 25 10 2024
pubmed: 25 10 2024
entrez: 25 10 2024
Statut: epublish

Résumé

Curcumin, a polyphenolic compound derived from the widely used spice

Identifiants

DOI: 10.3390/cells13201673 PMID: 39451191
pubmed: 39451191
pii: cells13201673
doi: 10.3390/cells13201673
pii:
doi:

Substances chimiques

MicroRNAs 0
GPI-Linked Proteins 0
RECK protein, human 0
Curcumin IT942ZTH98
Interleukin-18 0
TRAF3IP2 protein, human 0
Adaptor Proteins, Signal Transducing 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : US Department of Veterans Affairs
ID : I01 BX005845,
Organisme : BLRD VA
ID : I01 BX003271
Pays : United States
Organisme : US Department of Veterans Affairs
ID : IK6BX004016
Organisme : NIDDK NIH HHS
ID : DK130243
Pays : United States
Organisme : NHLBI NIH HHS
ID : HL070241
Pays : United States
Organisme : NIAAA NIH HHS
ID : R21AA029747
Pays : United States

Auteurs

Yusuke Higashi (Y)

Medicine/Cardiology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
ORCID: 0000-0003-1956-0182

Ryan Dashek (R)

NextGen Precision Health, University of Missouri, Columbia, MO 65211, USA.
Comparative Medicine Program, University of Missouri, Columbia, MO 65211, USA.
Research Service, Harry S. Truman Memorial Veterans Hospital, Columbia, MO 65201, USA.
Department of Medicine, Division of Gastroenterology and Hepatology, University of Missouri, Columbia, MO 65201, USA.

Patrice Delafontaine (P)

Medicine/Cardiology, Tulane University School of Medicine, New Orleans, LA 70112, USA.
ORCID: 0000-0003-3744-3617

Randy Scott Rector (RS)

NextGen Precision Health, University of Missouri, Columbia, MO 65211, USA.
Research Service, Harry S. Truman Memorial Veterans Hospital, Columbia, MO 65201, USA.
Department of Medicine, Division of Gastroenterology and Hepatology, University of Missouri, Columbia, MO 65201, USA.
Department of Nutrition and Exercise Physiology, University of Missouri, Columbia, MO 65201, USA.

Bysani Chandrasekar (B)

Research Service, Harry S. Truman Memorial Veterans Hospital, Columbia, MO 65201, USA.
Department of Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO 65201, USA.
Department of Medical Pharmacology and Physiology, University of Missouri, Columbia, MO 65201, USA.
Dalton Cardiovascular Center, University of Missouri, Columbia, MO 65203, USA.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › EF24, a Curcumin Analog, Reverses...
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › Petit ARN non traduit › microARN › EF24, a Curcumin Analog, Reverses...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Glycoprotéines membranaires › Protéines liées au GPI › EF24, a Curcumin Analog, Reverses...
questionsmedicales.fr › Composés chimiques organiques › Hydrocarbures › Hydrocarbures cycliques › Hydrocarbures aromatiques › Diarylheptanoïdes › Curcumine › EF24, a Curcumin Analog, Reverses...
questionsmedicales.fr › Système cardiovasculaire › Vaisseaux sanguins › Artères › Aorte › EF24, a Curcumin Analog, Reverses...
questionsmedicales.fr › Cellules › Cellules musculaires › Myocytes du muscle lisse › EF24, a Curcumin Analog, Reverses...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › Interleukines › Interleukine-18 › EF24, a Curcumin Analog, Reverses...
questionsmedicales.fr › Phénomènes génétiques › Phénotype › EF24, a Curcumin Analog, Reverses...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protéines adaptatrices de la transduction du signal › EF24, a Curcumin Analog, Reverses...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Inflammation › EF24, a Curcumin Analog, Reverses...
questionsmedicales.fr › Cellules › Cellules cultivées › EF24, a Curcumin Analog, Reverses...