Improving Hydrolytic Activity and Enantioselectivity of Epoxide Hydrolase from

Epoxide Hydrolases / metabolism Phanerochaete / enzymology Directed Molecular Evolution Molecular Docking Simulation Hydrolysis Substrate Specificity Mutagenesis, Site-Directed Stereoisomerism Mutation
Phanerochaete chrysosporium directed evolution enantioselectivity epoxide hydrolases molecular docking

Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
14 Oct 2024
Historique:
received: 16 07 2024
revised: 23 09 2024
accepted: 07 10 2024
medline: 26 10 2024
pubmed: 26 10 2024
entrez: 26 10 2024
Statut: epublish

Résumé

Epoxide hydrolases (EHs) catalyze the conversion of epoxides into vicinal diols. The epoxide hydrolase gene from

Identifiants

DOI: 10.3390/molecules29204864 PMID: 39459231
pubmed: 39459231
pii: molecules29204864
doi: 10.3390/molecules29204864
pii:
doi:

Substances chimiques

Epoxide Hydrolases EC 3.3.2.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : National Natural Science Foundation of China
ID : 21472132
Organisme : Natural Science Foundation of Sichuan Province
ID : 2022NSFSC0111
Organisme : Natural Science Foundation of Sichuan Province
ID : 2023NSFSC0133

Auteurs

Huanhuan Shao (H)

College of Life Sciences, Sichuan Normal University, Chenglong Avenue, Chengdu 610101, China.

Pan Xu (P)

College of Life Sciences, Sichuan Normal University, Chenglong Avenue, Chengdu 610101, China.
Sichuan Institute of Atomic Energy, Yidu West Road, Chengdu 610101, China.

Xiang Tao (X)

College of Life Sciences, Sichuan Normal University, Chenglong Avenue, Chengdu 610101, China.

Xinyi He (X)

College of Life Sciences, Sichuan Normal University, Chenglong Avenue, Chengdu 610101, China.

Chunyan Pu (C)

College of Life Sciences, Sichuan Normal University, Chenglong Avenue, Chengdu 610101, China.

Shaorong Liang (S)

College of Life Sciences, Sichuan Normal University, Chenglong Avenue, Chengdu 610101, China.

Yingxin Shi (Y)

College of Life Sciences, Sichuan Normal University, Chenglong Avenue, Chengdu 610101, China.

Xiaoyan Wang (X)

College of Life Sciences, Sichuan Normal University, Chenglong Avenue, Chengdu 610101, China.

Hong Feng (H)

College of Life Sciences, Sichuan University, Wangjiang Road, Chengdu 610199, China.
ORCID: 0000-0001-6917-4250

Bin Yong (B)

College of Life Sciences, Sichuan Normal University, Chenglong Avenue, Chengdu 610101, China.

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Epoxide hydrolase › Improving Hydrolytic Activity and...
questionsmedicales.fr › Eucaryotes › Champignons › Basidiomycota › Polyporales › Phanerochaete › Improving Hydrolytic Activity and...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Évolution moléculaire dirigée › Improving Hydrolytic Activity and...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de docking moléculaire › Improving Hydrolytic Activity and...
questionsmedicales.fr › Phénomènes chimiques › Hydrolyse › Improving Hydrolytic Activity and...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Spécificité du substrat › Improving Hydrolytic Activity and...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Génie génétique › Ingénierie des protéines › Mutagenèse dirigée › Improving Hydrolytic Activity and...
questionsmedicales.fr › Phénomènes chimiques › Phénomènes de chimie organique › Isomérie › Stéréoisomérie › Improving Hydrolytic Activity and...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Improving Hydrolytic Activity and...