A receptor kinase senses sterol by coupling with elicitins in auxotrophic
elicitin
oomycete
receptor kinase
sterol
Journal
Proceedings of the National Academy of Sciences of the United States of America
ISSN: 1091-6490
Titre abrégé: Proc Natl Acad Sci U S A
Pays: United States
ID NLM: 7505876
Informations de publication
Date de publication:
05 Nov 2024
05 Nov 2024
Historique:
medline:
30
10
2024
pubmed:
30
10
2024
entrez:
30
10
2024
Statut:
ppublish
Résumé
Sterols are vital nutrients and signals for eukaryotic organisms. Mammalian cells are known to sense and respond to sterol status changes to maintain them within strict limits, a process associated with various human diseases. However, this process is not understood in oomycete pathogens, most of which are sterol auxotrophic and must obtain sterols from host plants. Here, we report that
Identifiants
pubmed: 39475635
doi: 10.1073/pnas.2408186121
doi:
Substances chimiques
Sterols
0
elicitin, Phytophthora
0
Protein Kinases
EC 2.7.-
Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e2408186121Subventions
Organisme : MOST | National Natural Science Foundation of China (NSFC)
ID : 32230089
Organisme : MOST | National Natural Science Foundation of China (NSFC)
ID : 32202251
Organisme : MOST | National Natural Science Foundation of China (NSFC)
ID : 32372493
Organisme : National Natural Science Foundation of Jiangsu Province
ID : BK20221000
Organisme : MOE | Fundamental Research Funds for the Central Universities (Fundamental Research Fund for the Central Universities)
ID : KYQN2023039
Organisme : MOA | Earmarked Fund for China Agriculture Research System
ID : CARS-21
Organisme : Graduate Research Innovation program of Jiangsu Province
ID : KYCX22_0762
Déclaration de conflit d'intérêts
Competing interests statement:The authors declare no competing interest.