Adam Zlotnick

Affiliations

Department of Molecular and Cellular Biochemistry , Indiana University , Bloomington , Indiana 47405 , United States.

ORCID: 0000-0001-9945-6267

Publications (21)

Assembly Reactions of Hepatitis B Capsid Protein into Capsid Nanoparticles Follow a Narrow Path through a Complex Reaction Landscape.

ACS nano

Avec: Roi Asor , Lisa Selzer , Christopher John Schlicksup , Zhongchao Zhao , Adam Zlotnick , Uri Raviv

Competition between Normative and Drug-Induced Virus Self-Assembly Observed with Single-Particle Methods.

Journal of the American Chemical Society

Avec: Panagiotis Kondylis , Christopher J Schlicksup , Nicholas E Brunk , Jinsheng Zhou , Adam Zlotnick , Stephen C Jacobson

Virus self-assembly proceeds through contact-rich energy minima.

Science advances

Avec: Pedro Buzón , Sourav Maity , Panagiotis Christodoulis , Monique J Wiertsema , Steven Dunkelbarger , Christine Kim , Gijs J L Wuite , Adam Zlotnick , Wouter H Roos

A narrow ratio of nucleic acid to SARS-CoV-2 N-protein enables phase separation.

bioRxiv : the preprint server for biology

Avec: Patrick M Laughlin , Kimberly Young , Giovanni Gonzalez-Gutierrez , Joseph C Y Wang , Adam Zlotnick

Higher Resolution Charge Detection Mass Spectrometry.

Analytical chemistry

Avec: Aaron R Todd , Lauren F Barnes , Kim Young , Adam Zlotnick , Martin F Jarrold

Disassembly of Single Virus Capsids Monitored in Real Time with Multicycle Resistive-Pulse Sensing.

Analytical chemistry

Avec: Jinsheng Zhou , Adam Zlotnick , Stephen C Jacobson

The unique potency of Cowpea mosaic virus (CPMV)

Biomaterials science

Avec: Sourabh Shukla , Chao Wang , Veronique Beiss , Hui Cai , Torus Washington , Abner A Murray , Xingjian Gong , Zhongchao Zhao , Hema Masarapu , Adam Zlotnick , Steven Fiering , Nicole F Steinmetz

HBV Core Protein Is in Flux between Cytoplasmic, Nuclear, and Nucleolar Compartments.

mBio

Avec: Smita Nair , Adam Zlotnick

Engineering Metastability into a Virus-like Particle to Enable Triggered Dissociation.

Journal of the American Chemical Society

Avec: Caleb A Starr , Smita Nair , Sheng-Yuan Huang , Michael F Hagan , Stephen C Jacobson , Adam Zlotnick

Asymmetrizing an icosahedral virus capsid by hierarchical assembly of subunits with designed asymmetry.

Nature communications

Avec: Zhongchao Zhao , Joseph Che-Yen Wang , Mi Zhang , Nicholas A Lyktey , Martin F Jarrold , Stephen C Jacobson , Adam Zlotnick

Evolution of Intermediates during Capsid Assembly of Hepatitis B Virus with Phenylpropenamide-Based Antivirals.

ACS infectious diseases

Avec: Panagiotis Kondylis , Christopher J Schlicksup , Sarah P Katen , Lye Siang Lee , Adam Zlotnick , Stephen C Jacobson

Dynamics of Hepatitis B Virus Capsid Protein Dimer Regulate Assembly through an Allosteric Network.

ACS chemical biology

Avec: Angela Patterson , Zhongchao Zhao , Elizabeth Waymire , Adam Zlotnick , Brian Bothner

Core Protein-Directed Antivirals and Importin β Can Synergistically Disrupt Hepatitis B Virus Capsids.

Journal of virology

Avec: Christine Kim , Lauren F Barnes , Christopher J Schlicksup , Angela J Patterson , Brian Bothner , Martin F Jarrold , Che-Yen Joseph Wang , Adam Zlotnick

In-Plane, In-Series Nanopores with Circular Cross Sections for Resistive-Pulse Sensing.

ACS nano

Avec: Mi Zhang , Zachary D Harms , Tine Greibe , Caleb A Starr , Adam Zlotnick , Stephen C Jacobson

Multiscale Modeling of Hepatitis B Virus Capsid Assembly and Its Dimorphism.

ACS nano

Avec: Farzaneh Mohajerani , Botond Tyukodi , Christopher J Schlicksup , Jodi A Hadden-Perilla , Adam Zlotnick , Michael F Hagan

Heterogeneity of HPV16 virus-like particles indicates a complex assembly energy surface.

Virology

Avec: Angela Patterson , Kim Young , MacRyan P Biever , Shelby M Klein , Sheng-Yuan Huang , Pete A DePhillips , Stephen C Jacobson , Martin F Jarrold , Adam Zlotnick

Rapidly Forming Early Intermediate Structures Dictate the Pathway of Capsid Assembly.

Journal of the American Chemical Society

Avec: Roi Asor , Christopher John Schlicksup , Zhongchao Zhao , Adam Zlotnick , Uri Raviv

Structural basis for nuclear import of hepatitis B virus (HBV) nucleocapsid core.

Science advances

Avec: Ruoyu Yang , Ying-Hui Ko , Fenglin Li , Ravi K Lokareddy , Chun-Feng David Hou , Christine Kim , Shelby Klein , Santiago Antolínez , Juan F Marín , Carolina Pérez-Segura , Martin F Jarrold , Adam Zlotnick , Jodi A Hadden-Perilla , Gino Cingolani

Guanidine Hydrochloride-Induced Hepatitis B Virus Capsid Disassembly Hysteresis.

Biochemistry

Avec: Daniel Khaykelson , Roi Asor , Zhongchao Zhao , Christopher John Schlicksup , Adam Zlotnick , Uri Raviv

Small Molecule Assembly Agonist Alters the Dynamics of Hepatitis B Virus Core Protein Dimer and Capsid.

Journal of the American Chemical Society

Avec: Ravi Kant , Lye-Siang Lee , Angela Patterson , Nora Gibes , Balasubramanian Venkatakrishnan , Adam Zlotnick , Brian Bothner

Structural Differences between the Woodchuck Hepatitis Virus Core Protein in the Dimer and Capsid States Are Consistent with Entropic and Conformational Regulation of Assembly.

Journal of virology

Avec: Zhongchao Zhao , Joseph Che-Yen Wang , Giovanni Gonzalez-Gutierrez , Balasubramanian Venkatakrishnan , Roi Asor , Daniel Khaykelson , Uri Raviv , Adam Zlotnick

Réseau de co-auteurs

Zhongchao Zhao 7 collaborations

Stephen C Jacobson 7 collaborations

Martin F Jarrold 5 collaborations

Roi Asor 4 collaborations

Uri Raviv 4 collaborations

Christopher J Schlicksup 4 collaborations

Christopher John Schlicksup 3 collaborations

Christine Kim 3 collaborations

Angela Patterson 3 collaborations

Brian Bothner 3 collaborations

Panagiotis Kondylis 2 collaborations

Jinsheng Zhou 2 collaborations

Giovanni Gonzalez-Gutierrez 2 collaborations

Lauren F Barnes 2 collaborations

Kim Young 2 collaborations

Smita Nair 2 collaborations

Caleb A Starr 2 collaborations

Sheng-Yuan Huang 2 collaborations

Michael F Hagan 2 collaborations

Joseph Che-Yen Wang 2 collaborations

Mi Zhang 2 collaborations

Jodi A Hadden-Perilla 2 collaborations

Daniel Khaykelson 2 collaborations

Balasubramanian Venkatakrishnan 2 collaborations

Lisa Selzer 1 collaboration

Nicholas E Brunk 1 collaboration

Pedro Buzón 1 collaboration

Sourav Maity 1 collaboration

Panagiotis Christodoulis 1 collaboration

Monique J Wiertsema 1 collaboration

Steven Dunkelbarger 1 collaboration

Gijs J L Wuite 1 collaboration

Wouter H Roos 1 collaboration

Patrick M Laughlin 1 collaboration

Kimberly Young 1 collaboration

Joseph C Y Wang 1 collaboration

Aaron R Todd 1 collaboration

Sourabh Shukla 1 collaboration

Chao Wang 1 collaboration

Veronique Beiss 1 collaboration

Hui Cai 1 collaboration

Torus Washington 1 collaboration

Abner A Murray 1 collaboration

Xingjian Gong 1 collaboration

Hema Masarapu 1 collaboration

Steven Fiering 1 collaboration

Nicole F Steinmetz 1 collaboration

Nicholas A Lyktey 1 collaboration

Sarah P Katen 1 collaboration

Lye Siang Lee 1 collaboration

Elizabeth Waymire 1 collaboration

Angela J Patterson 1 collaboration

Che-Yen Joseph Wang 1 collaboration

Zachary D Harms 1 collaboration

Tine Greibe 1 collaboration

Farzaneh Mohajerani 1 collaboration

Botond Tyukodi 1 collaboration

MacRyan P Biever 1 collaboration

Shelby M Klein 1 collaboration

Pete A DePhillips 1 collaboration

Ruoyu Yang 1 collaboration

Ying-Hui Ko 1 collaboration

Fenglin Li 1 collaboration

Ravi K Lokareddy 1 collaboration

Chun-Feng David Hou 1 collaboration

Shelby Klein 1 collaboration

Santiago Antolínez 1 collaboration

Juan F Marín 1 collaboration

Carolina Pérez-Segura 1 collaboration

Gino Cingolani 1 collaboration

Ravi Kant 1 collaboration

Lye-Siang Lee 1 collaboration

Nora Gibes 1 collaboration