Alena Savonenko

Affiliations

Department of Pathology (Neuropathology), Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Publications (19)

Molecular imaging of the serotonin transporter availability and occupancy by antidepressant treatment in late-life depression.

Neuropharmacology

Avec: Gwenn S Smith , Hiroto Kuwabara , Neda F Gould , Najilla Nassery , Alena Savonenko , Jin Hui Joo , Kristin L Bigos , Michael Kraut , James Brasic , Daniel P Holt , Andrew W Hall , William B Mathews , Robert F Dannals , Ayon Nandi , Clifford I Workman

Animal Models of Psychosis in Alzheimer Disease.

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

Avec: Josh M Krivinko , Jeremy Koppel , Alena Savonenko , Robert A Sweet

A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21.

eLife

Avec: Yasuhiro Kazuki , Feng J Gao , Yicong Li , Anna J Moyer , Benjamin Devenney , Kei Hiramatsu , Sachiko Miyagawa-Tomita , Satoshi Abe , Kanako Kazuki , Naoyo Kajitani , Narumi Uno , Shoko Takehara , Masato Takiguchi , Miho Yamakawa , Atsushi Hasegawa , Ritsuko Shimizu , Satoko Matsukura , Naohiro Noda , Narumi Ogonuki , Kimiko Inoue , Shogo Matoba , Atsuo Ogura , Liliana D Florea , Alena Savonenko , Meifang Xiao , Dan Wu , Denise As Batista , Junhua Yang , Zhaozhu Qiu , Nandini Singh , Joan T Richtsmeier , Takashi Takeuchi , Mitsuo Oshimura , Roger H Reeves

Persistently Elevated mTOR Complex 1-S6 Kinase 1 Disrupts DARPP-32-Dependent D

Biological psychiatry

Avec: Raozhou Lin , Lisa N Learman , Chan-Hyun Na , Santosh Renuse , Kevin T Chen , Po Yu Chen , Gum-Hwa Lee , Bo Xiao , Susan M Resnick , Juan C Troncoso , Karen K Szumlinski , David J Linden , Joo-Min Park , Alena Savonenko , Akhilesh Pandey , Paul F Worley

Strain-specific pre-existing immunity: A key to understanding the role of chronic Toxoplasma infection in cognition and Alzheimer's diseases?

Neuroscience and biobehavioral reviews

Avec: Jianchun Xiao , Alena Savonenko , Robert H Yolken

Sleep and circadian rhythm disruption by NPTX2 loss of function.

bioRxiv : the preprint server for biology

Avec: Seung-Eon Roh , Meifang Xiao , Ana Delgado , Chuljung Kwak , Alena Savonenko , Arnold Bakker , Hyung-Bae Kwon , Paul Worley

Regional amyloid correlates of cognitive performance in ageing and mild cognitive impairment.

Brain communications

Avec: Daniel A Stevens , Clifford I Workman , Hiroto Kuwabara , Meryl A Butters , Alena Savonenko , Najilla Nassery , Neda Gould , Michael Kraut , Jin Hui Joo , Jessica Kilgore , Vidya Kamath , Daniel P Holt , Robert F Dannals , Ayon Nandi , Chiadi U Onyike , Gwenn S Smith

Serotonin Degeneration and Amyloid-β Deposition in Mild Cognitive Impairment: Relationship to Cognitive Deficits.

Journal of Alzheimer's disease : JAD

Avec: Gwenn S Smith , Hiroto Kuwabara , Haijuan Yan , Najlla Nassery , Mark Yoon , Vidya Kamath , Michael Kraut , Neda F Gould , Alena Savonenko , Jennifer M Coughlin , Martin Lodge , Martin G Pomper , Ayon Nandi , Daniel Holt , Robert F Dannals , Jeannie M Leoutsakos

Molecular imaging of the association between serotonin degeneration and beta-amyloid deposition in mild cognitive impairment.

NeuroImage. Clinical

Avec: Gwenn S Smith , Hillary Protas , Hiroto Kuwabara , Alena Savonenko , Najlla Nassery , Neda F Gould , Michael Kraut , Dimitri Avramopoulos , Daniel Holt , Robert F Dannals , Ayon Nandi , Yi Su , Eric M Reiman , Kewei Chen

Hydroxyurea Improves Spatial Memory and Cognitive Plasticity in Mice and Has a Mild Effect on These Parameters in a Down Syndrome Mouse Model.

Frontiers in aging neuroscience

Avec: Rebecca Deering Brose , Alena Savonenko , Benjamin Devenney , Kirby D Smith , Roger H Reeves

A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function.

Science advances

Avec: Mei-Fang Xiao , Seung-Eon Roh , Jiechao Zhou , Chun-Che Chien , Brendan P Lucey , Michael T Craig , Lindsay N Hayes , Jennifer M Coughlin , F Markus Leweke , Min Jia , Desheng Xu , Weiqiang Zhou , C Conover Talbot , Don B Arnold , Melissa Staley , Cindy Jiang , Irving M Reti , Akira Sawa , Kenneth A Pelkey , Chris J McBain , Alena Savonenko , Paul F Worley

Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates.

Acta neuropathologica communications

Avec: Feng J Gao , Donna Klinedinst , Fabian-Xosé Fernandez , Bei Cheng , Alena Savonenko , Benjamin Devenney , Yicong Li , Dan Wu , Martin G Pomper , Roger H Reeves

Depression-related phenotypes at early stages of Aβ and tau accumulation in inducible Alzheimer's disease mouse model: Task-oriented and concept-driven interpretations.

Behavioural brain research

Avec: Erica Leyder , Prakul Suresh , Rachel Jun , Katherine Overbey , Tirtho Banerjee , Tatiana Melnikova , Alena Savonenko

Loss of GDE2 leads to complex behavioral changes including memory impairment.

Behavioral and brain functions : BBF

Avec: Daniel Daudelin , Anna Westerhaus , Nan Zhang , Erica Leyder , Alena Savonenko , Shanthini Sockanathan

Arc Oligomerization Is Regulated by CaMKII Phosphorylation of the GAG Domain: An Essential Mechanism for Plasticity and Memory Formation.

Molecular cell

Avec: Wenchi Zhang , Yang-An Chuang , Youn Na , Zengyou Ye , Liuqing Yang , Raozhou Lin , Jiechao Zhou , Jing Wu , Jessica Qiu , Alena Savonenko , Daniel J Leahy , Richard Huganir , David J Linden , Paul F Worley

Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome.

Cell reports

Avec: Raozhou Lin , Lisa N Learman , M Ali Bangash , Tatiana Melnikova , Erica Leyder , Sai C Reddy , Nirinjini Naidoo , Joo Min Park , Alena Savonenko , Paul F Worley

Molecular imaging of beta-amyloid deposition in late-life depression.

Neurobiology of aging

Avec: Gwenn S Smith , Hiroto Kuwabara , Ayon Nandi , Neda F Gould , Najilla Nassery , Alena Savonenko , Jin Hui Joo , Michael Kraut , James Brasic , Daniel P Holt , Andrew W Hall , William B Mathews , Robert F Dannals , Dimitrios Avramopoulos , Clifford I Workman

Positron emission tomography imaging of serotonin degeneration and beta-amyloid deposition in late-life depression evaluated with multi-modal partial least squares.

Translational psychiatry

Avec: Gwenn S Smith , Clifford I Workman , Hillary Protas , Yi Su , Alena Savonenko , Hiroto Kuwabara , Neda F Gould , Michael Kraut , Jin Hui Joo , Ayon Nandi , Dimitri Avramopoulos , Eric M Reiman , Kewei Chen

Importance of Control Groups for Evaluating Long-Term Behavioral and Cognitive Outcomes of Controlled Cortical Impact in Immature Rats.

Journal of neurotrauma

Avec: Nagat El-Demerdash , Tiffany Pan , Olivia Choi , Manda Saraswati , Raymond C Koehler , Courtney L Robertson , Alena Savonenko

Réseau de co-auteurs

Gwenn S Smith 6 collaborations

Hiroto Kuwabara 6 collaborations

Michael Kraut 6 collaborations

Ayon Nandi 6 collaborations

Neda F Gould 5 collaborations

Robert F Dannals 5 collaborations

Jin Hui Joo 4 collaborations

Clifford I Workman 4 collaborations

Paul F Worley 4 collaborations

Najilla Nassery 3 collaborations

Daniel P Holt 3 collaborations

Benjamin Devenney 3 collaborations

Roger H Reeves 3 collaborations

Raozhou Lin 3 collaborations

Erica Leyder 3 collaborations

James Brasic 2 collaborations

Andrew W Hall 2 collaborations

William B Mathews 2 collaborations

Feng J Gao 2 collaborations

Yicong Li 2 collaborations

Meifang Xiao 2 collaborations

Dan Wu 2 collaborations

Lisa N Learman 2 collaborations

David J Linden 2 collaborations

Seung-Eon Roh 2 collaborations

Vidya Kamath 2 collaborations

Najlla Nassery 2 collaborations

Jennifer M Coughlin 2 collaborations

Martin G Pomper 2 collaborations

Daniel Holt 2 collaborations

Hillary Protas 2 collaborations

Dimitri Avramopoulos 2 collaborations

Yi Su 2 collaborations

Eric M Reiman 2 collaborations

Kewei Chen 2 collaborations

Jiechao Zhou 2 collaborations

Tatiana Melnikova 2 collaborations

Kristin L Bigos 1 collaboration

Josh M Krivinko 1 collaboration

Jeremy Koppel 1 collaboration

Robert A Sweet 1 collaboration

Yasuhiro Kazuki 1 collaboration

Anna J Moyer 1 collaboration

Kei Hiramatsu 1 collaboration

Sachiko Miyagawa-Tomita 1 collaboration

Satoshi Abe 1 collaboration

Kanako Kazuki 1 collaboration

Naoyo Kajitani 1 collaboration

Narumi Uno 1 collaboration

Shoko Takehara 1 collaboration

Masato Takiguchi 1 collaboration

Miho Yamakawa 1 collaboration

Atsushi Hasegawa 1 collaboration

Ritsuko Shimizu 1 collaboration

Satoko Matsukura 1 collaboration

Naohiro Noda 1 collaboration

Narumi Ogonuki 1 collaboration

Kimiko Inoue 1 collaboration

Shogo Matoba 1 collaboration

Atsuo Ogura 1 collaboration

Liliana D Florea 1 collaboration

Denise As Batista 1 collaboration

Junhua Yang 1 collaboration

Zhaozhu Qiu 1 collaboration

Nandini Singh 1 collaboration

Joan T Richtsmeier 1 collaboration

Takashi Takeuchi 1 collaboration

Mitsuo Oshimura 1 collaboration

Chan-Hyun Na 1 collaboration

Santosh Renuse 1 collaboration

Kevin T Chen 1 collaboration

Po Yu Chen 1 collaboration

Gum-Hwa Lee 1 collaboration

Bo Xiao 1 collaboration

Susan M Resnick 1 collaboration

Juan C Troncoso 1 collaboration

Karen K Szumlinski 1 collaboration

Joo-Min Park 1 collaboration

Akhilesh Pandey 1 collaboration

Jianchun Xiao 1 collaboration

Robert H Yolken 1 collaboration

Ana Delgado 1 collaboration

Chuljung Kwak 1 collaboration

Arnold Bakker 1 collaboration

Hyung-Bae Kwon 1 collaboration

Paul Worley 1 collaboration

Daniel A Stevens 1 collaboration

Meryl A Butters 1 collaboration

Neda Gould 1 collaboration

Jessica Kilgore 1 collaboration

Chiadi U Onyike 1 collaboration

Haijuan Yan 1 collaboration

Mark Yoon 1 collaboration

Martin Lodge 1 collaboration

Jeannie M Leoutsakos 1 collaboration

Rebecca Deering Brose 1 collaboration

Kirby D Smith 1 collaboration

Mei-Fang Xiao 1 collaboration

Chun-Che Chien 1 collaboration

Brendan P Lucey 1 collaboration

Michael T Craig 1 collaboration

Lindsay N Hayes 1 collaboration

F Markus Leweke 1 collaboration

Min Jia 1 collaboration

Desheng Xu 1 collaboration

Weiqiang Zhou 1 collaboration

C Conover Talbot 1 collaboration

Don B Arnold 1 collaboration

Melissa Staley 1 collaboration

Cindy Jiang 1 collaboration

Irving M Reti 1 collaboration

Akira Sawa 1 collaboration

Kenneth A Pelkey 1 collaboration

Chris J McBain 1 collaboration

Donna Klinedinst 1 collaboration

Fabian-Xosé Fernandez 1 collaboration

Bei Cheng 1 collaboration

Prakul Suresh 1 collaboration

Rachel Jun 1 collaboration

Katherine Overbey 1 collaboration

Tirtho Banerjee 1 collaboration

Daniel Daudelin 1 collaboration

Anna Westerhaus 1 collaboration

Nan Zhang 1 collaboration

Shanthini Sockanathan 1 collaboration

Wenchi Zhang 1 collaboration

Yang-An Chuang 1 collaboration

Youn Na 1 collaboration

Zengyou Ye 1 collaboration

Liuqing Yang 1 collaboration

Jing Wu 1 collaboration

Jessica Qiu 1 collaboration

Daniel J Leahy 1 collaboration

Richard Huganir 1 collaboration

M Ali Bangash 1 collaboration

Sai C Reddy 1 collaboration

Nirinjini Naidoo 1 collaboration

Joo Min Park 1 collaboration

Dimitrios Avramopoulos 1 collaboration

Nagat El-Demerdash 1 collaboration

Tiffany Pan 1 collaboration

Olivia Choi 1 collaboration

Manda Saraswati 1 collaboration

Raymond C Koehler 1 collaboration

Courtney L Robertson 1 collaboration