Amarendra Pegu

Affiliations
  • Vaccine Research Center, NIAID, NIH, Bethesda, USA.

Publications (43)

Bispecific antibodies: Potential immunotherapies for HIV treatment.

Methods (San Diego, Calif.)
Avec: Giulia Fabozzi , Amarendra Pegu , Richard A Koup , Constantinos Petrovas

Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound.

The Journal of clinical investigation
Avec: Evan M Cale , Hongjun Bai , Meera Bose , Michael A Messina , Donn J Colby , Eric Sanders-Buell , Bethany Dearlove , Yifan Li , Emily Engeman , Daniel Silas , Anne Marie O'Sullivan , Brendan Mann , Suteeraporn Pinyakorn , Jintana Intasan , Khunthalee Benjapornpong , Carlo Sacdalan , Eugène Kroon , Nittaya Phanuphak , Robert Gramzinski , Sandhya Vasan , Merlin L Robb , Nelson L Michael , Rebecca M Lynch , Robert T Bailer , Amélie Pagliuzza , Nicolas Chomont , Amarendra Pegu , Nicole A Doria-Rose , Lydie Trautmann , Trevor A Crowell , John R Mascola , Jintanat Ananworanich , Sodsai Tovanabutra , Morgane Rolland , Auteur inconnu

A Meta-analysis of Passive Immunization Studies Shows that Serum-Neutralizing Antibody Titer Associates with Protection against SHIV Challenge.

Cell host & microbe
Avec: Amarendra Pegu , Bhavesh Borate , Yunda Huang , Matthias G Pauthner , Ann J Hessell , Boris Julg , Nicole A Doria-Rose , Stephen D Schmidt , Lindsay N Carpp , Michelle D Cully , Xuejun Chen , George M Shaw , Dan H Barouch , Nancy L Haigwood , Lawrence Corey , Dennis R Burton , Mario Roederer , Peter B Gilbert , John R Mascola , Ying Huang

Fusion peptide priming reduces immune responses to HIV-1 envelope trimer base.

Cell reports
Avec: Angela R Corrigan , Hongying Duan , Cheng Cheng , Christopher A Gonelli , Li Ou , Kai Xu , Megan E DeMouth , Hui Geng , Sandeep Narpala , Sarah O'Connell , Baoshan Zhang , Tongqing Zhou , Manjula Basappa , Jeffrey C Boyington , Steven J Chen , Sijy O'Dell , Amarendra Pegu , Tyler Stephens , Yaroslav Tsybovsky , Jelle van Schooten , John P Todd , Shuishu Wang , Auteur inconnu , Nicole A Doria-Rose , Kathryn E Foulds , Richard A Koup , Adrian B McDermott , Marit J van Gils , Peter D Kwong , John R Mascola

Antibodies targeting the fusion peptide on the HIV envelope provide protection to rhesus macaques against mucosal SHIV challenge.

Science translational medicine
Avec: Amarendra Pegu , Sarah E Lovelace , Megan E DeMouth , Michelle D Cully , Daniel J Morris , Yingying Li , Keyun Wang , Stephen D Schmidt , Misook Choe , Cuiping Liu , Xuejun Chen , Elise Viox , Ariana Rowshan , Justin D Taft , Baoshan Zhang , Kai Xu , Hongying Duan , Li Ou , John-Paul Todd , Rui Kong , Hui Li , George M Shaw , Nicole A Doria-Rose , Peter D Kwong , Richard A Koup , John R Mascola

Selection of positive controls and their impact on anti-drug antibody assay performance.

Journal of immunological methods
Avec: Joshua A Weiner , Harini Natarajan , Calum J McIntosh , Eun Sung Yang , Misook Choe , Cassidy L Papia , Katherine S Axelrod , Gabriela Kovacikova , Amarendra Pegu , Margaret E Ackerman

Evaluation of the mRNA-1273 Vaccine against SARS-CoV-2 in Nonhuman Primates.

The New England journal of medicine
Avec: Kizzmekia S Corbett , Barbara Flynn , Kathryn E Foulds , Joseph R Francica , Seyhan Boyoglu-Barnum , Anne P Werner , Britta Flach , Sarah O'Connell , Kevin W Bock , Mahnaz Minai , Bianca M Nagata , Hanne Andersen , David R Martinez , Amy T Noe , Naomi Douek , Mitzi M Donaldson , Nadesh N Nji , Gabriela S Alvarado , Darin K Edwards , Dillon R Flebbe , Evan Lamb , Nicole A Doria-Rose , Bob C Lin , Mark K Louder , Sijy O'Dell , Stephen D Schmidt , Emily Phung , Lauren A Chang , Christina Yap , John-Paul M Todd , Laurent Pessaint , Alex Van Ry , Shanai Browne , Jack Greenhouse , Tammy Putman-Taylor , Amanda Strasbaugh , Tracey-Ann Campbell , Anthony Cook , Alan Dodson , Katelyn Steingrebe , Wei Shi , Yi Zhang , Olubukola M Abiona , Lingshu Wang , Amarendra Pegu , Eun Sung Yang , Kwanyee Leung , Tongqing Zhou , I-Ting Teng , Alicia Widge , Ingelise Gordon , Laura Novik , Rebecca A Gillespie , Rebecca J Loomis , Juan I Moliva , Guillaume Stewart-Jones , Sunny Himansu , Wing-Pui Kong , Martha C Nason , Kaitlyn M Morabito , Tracy J Ruckwardt , Julie E Ledgerwood , Martin R Gaudinski , Peter D Kwong , John R Mascola , Andrea Carfi , Mark G Lewis , Ralph S Baric , Adrian McDermott , Ian N Moore , Nancy J Sullivan , Mario Roederer , Robert A Seder , Barney S Graham

Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody.

Proceedings of the National Academy of Sciences of the United States of America
Avec: Mangaiarkarasi Asokan , Joana Dias , Cuiping Liu , Anna Maximova , Keenan Ernste , Amarendra Pegu , Krisha McKee , Wei Shi , Xuejun Chen , Cassandra Almasri , Wanwisa Promsote , David R Ambrozak , Lucio Gama , Jianfei Hu , Daniel C Douek , John-Paul Todd , Jeffrey D Lifson , Slim Fourati , Rafick P Sekaly , Andrew R Crowley , Margaret E Ackerman , Sung Hee Ko , Divya Kilam , Eli A Boritz , Laura E Liao , Katharine Best , Alan S Perelson , John R Mascola , Richard A Koup

Anti-HIV-1 Antibodies: An Update.

BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy
Avec: Wanwisa Promsote , Megan E DeMouth , Cassandra G Almasri , Amarendra Pegu

CCR2-dependent monocyte-derived cells restrict SARS-CoV-2 infection.

bioRxiv : the preprint server for biology
Avec: Abigail Vanderheiden , Jeronay Thomas , Allison L Soung , Meredith E Davis-Gardner , Katharine Floyd , Fengzhi Jin , David A Cowan , Kathryn Pellegrini , Adrian Creanga , Amarendra Pegu , Alexandrine Derrien-Colemyn , Pei-Yong Shi , Arash Grakoui , Robyn S Klein , Steven E Bosinger , Jacob E Kohlmeier , Vineet D Menachery , Mehul S Suthar

Durability of mRNA-1273-induced antibodies against SARS-CoV-2 variants.

bioRxiv : the preprint server for biology
Avec: Amarendra Pegu , Sarah O'Connell , Stephen D Schmidt , Sijy O'Dell , Chloe A Talana , Lilin Lai , Jim Albert , Evan Anderson , Hamilton Bennett , Kizzmekia S Corbett , Britta Flach , Lisa Jackson , Brett Leav , Julie E Ledgerwood , Catherine J Luke , Mat Makowski , Paul C Roberts , Mario Roederer , Paulina A Rebolledo , Christina A Rostad , Nadine G Rouphael , Wei Shi , Lingshu Wang , Alicia T Widge , Eun Sung Yang , Auteur inconnu , John H Beigel , Barney S Graham , John R Mascola , Mehul S Suthar , Adrian McDermott , Nicole A Doria-Rose

Improved delivery of broadly neutralizing antibodies by nanocapsules suppresses SHIV infection in the CNS of infant rhesus macaques.

PLoS pathogens
Avec: Jing Wen , Tracy Cheever , Lan Wang , Di Wu , Jason Reed , John Mascola , Xuejun Chen , Cuiping Liu , Amarendra Pegu , Jonah B Sacha , Yunfeng Lu , Nancy L Haigwood , Irvin S Y Chen

Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.

Science (New York, N.Y.)
Avec: Lingshu Wang , Tongqing Zhou , Yi Zhang , Eun Sung Yang , Chaim A Schramm , Wei Shi , Amarendra Pegu , Olamide K Oloniniyi , Amy R Henry , Samuel Darko , Sandeep R Narpala , Christian Hatcher , David R Martinez , Yaroslav Tsybovsky , Emily Phung , Olubukola M Abiona , Avan Antia , Evan M Cale , Lauren A Chang , Misook Choe , Kizzmekia S Corbett , Rachel L Davis , Anthony T DiPiazza , Ingelise J Gordon , Sabrina Helmold Hait , Tandile Hermanus , Prudence Kgagudi , Farida Laboune , Kwanyee Leung , Tracy Liu , Rosemarie D Mason , Alexandra F Nazzari , Laura Novik , Sarah O'Connell , Sijy O'Dell , Adam S Olia , Stephen D Schmidt , Tyler Stephens , Christopher D Stringham , Chloe Adrienna Talana , I-Ting Teng , Danielle A Wagner , Alicia T Widge , Baoshan Zhang , Mario Roederer , Julie E Ledgerwood , Tracy J Ruckwardt , Martin R Gaudinski , Penny L Moore , Nicole A Doria-Rose , Ralph S Baric , Barney S Graham , Adrian B McDermott , Daniel C Douek , Peter D Kwong , John R Mascola , Nancy J Sullivan , John Misasi

Potent anti-viral activity of a trispecific HIV neutralizing antibody in SHIV-infected monkeys.

Cell reports
Avec: Amarendra Pegu , Ling Xu , Megan E DeMouth , Giulia Fabozzi , Kylie March , Cassandra G Almasri , Michelle D Cully , Keyun Wang , Eun Sung Yang , Joana Dias , Christine M Fennessey , Jason Hataye , Ronnie R Wei , Ercole Rao , Joseph P Casazza , Wanwisa Promsote , Mangaiarkarasi Asokan , Krisha McKee , Stephen D Schmidt , Xuejun Chen , Cuiping Liu , Wei Shi , Hui Geng , Kathryn E Foulds , Shing-Fen Kao , Amy Noe , Hui Li , George M Shaw , Tongqing Zhou , Constantinos Petrovas , John-Paul Todd , Brandon F Keele , Jeffrey D Lifson , Nicole A Doria-Rose , Richard A Koup , Zhi-Yong Yang , Gary J Nabel , John R Mascola

Structural basis for potent antibody neutralization of SARS-CoV-2 variants including B.1.1.529.

Science (New York, N.Y.)
Avec: Tongqing Zhou , Lingshu Wang , John Misasi , Amarendra Pegu , Yi Zhang , Darcy R Harris , Adam S Olia , Chloe Adrienna Talana , Eun Sung Yang , Man Chen , Misook Choe , Wei Shi , I-Ting Teng , Adrian Creanga , Claudia Jenkins , Kwanyee Leung , Tracy Liu , Erik-Stephane D Stancofski , Tyler Stephens , Baoshan Zhang , Yaroslav Tsybovsky , Barney S Graham , John R Mascola , Nancy J Sullivan , Peter D Kwong

Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability.

Structure (London, England : 1993)
Avec: Wei Shi , Lingshu Wang , Tongqing Zhou , Mallika Sastry , Eun Sung Yang , Yi Zhang , Man Chen , Xuejun Chen , Misook Choe , Adrian Creanga , Kwan Leung , Adam S Olia , Amarendra Pegu , Reda Rawi , Arne Schön , Chen-Hsiang Shen , Erik-Stephane D Stancofski , Chloe Adrienna Talana , I-Ting Teng , Shuishu Wang , Kizzmekia S Corbett , Yaroslav Tsybovsky , John R Mascola , Peter D Kwong

Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition.

Immunity
Avec: Wei-Hung Chen , JungHyun Kim , Wei Bu , Nathan L Board , Yaroslav Tsybovsky , Yanmei Wang , Anna Hostal , Sarah F Andrews , Rebecca A Gillespie , Misook Choe , Tyler Stephens , Eun Sung Yang , Amarendra Pegu , Caroline E Peterson , Brian E Fisher , John R Mascola , Stefania Pittaluga , Adrian B McDermott , Masaru Kanekiyo , M Gordon Joyce , Jeffrey I Cohen

Engineering of HIV-1 neutralizing antibody CAP256V2LS for manufacturability and improved half life.

Scientific reports
Avec: Baoshan Zhang , Deepika Gollapudi , Jason Gorman , Sijy O'Dell , Leland F Damron , Krisha McKee , Mangaiarkarasi Asokan , Eun Sung Yang , Amarendra Pegu , Bob C Lin , Cara W Chao , Xuejun Chen , Lucio Gama , Vera B Ivleva , William H Law , Cuiping Liu , Mark K Louder , Stephen D Schmidt , Chen-Hsiang Shen , Wei Shi , Judith A Stein , Michael S Seaman , Adrian B McDermott , Kevin Carlton , John R Mascola , Peter D Kwong , Q Paula Lei , Nicole A Doria-Rose

Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.

Nature communications
Avec: Noemia S Lima , Maryam Musayev , Timothy S Johnston , Danielle A Wagner , Amy R Henry , Lingshu Wang , Eun Sung Yang , Yi Zhang , Kevina Birungi , Walker P Black , Sijy O'Dell , Stephen D Schmidt , Damee Moon , Cynthia G Lorang , Bingchun Zhao , Man Chen , Kristin L Boswell , Jesmine Roberts-Torres , Rachel L Davis , Lowrey Peyton , Sandeep R Narpala , Sarah O'Connell , Leonid Serebryannyy , Jennifer Wang , Alexander Schrager , Chloe Adrienna Talana , Geoffrey Shimberg , Kwanyee Leung , Wei Shi , Rawan Khashab , Asaf Biber , Tal Zilberman , Joshua Rhein , Sara Vetter , Afeefa Ahmed , Laura Novik , Alicia Widge , Ingelise Gordon , Mercy Guech , I-Ting Teng , Emily Phung , Tracy J Ruckwardt , Amarendra Pegu , John Misasi , Nicole A Doria-Rose , Martin Gaudinski , Richard A Koup , Peter D Kwong , Adrian B McDermott , Sharon Amit , Timothy W Schacker , Itzchak Levy , John R Mascola , Nancy J Sullivan , Chaim A Schramm , Daniel C Douek

Delayed vaginal SHIV infection in VRC01 and anti-α4β7 treated rhesus macaques.

PLoS pathogens
Avec: Giulia Calenda , Ines Frank , Géraldine Arrode-Brusés , Amarendra Pegu , Keyun Wang , James Arthos , Claudia Cicala , Kenneth A Rogers , Lisa Shirreff , Brooke Grasperge , James L Blanchard , Stephanie Maldonado , Kevin Roberts , Agegnehu Gettie , Francois Villinger , Anthony S Fauci , John R Mascola , Elena Martinelli

A potently neutralizing SARS-CoV-2 antibody inhibits variants of concern by utilizing unique binding residues in a highly conserved epitope.

Immunity
Avec: Laura A VanBlargan , Lucas J Adams , Zhuoming Liu , Rita E Chen , Pavlo Gilchuk , Saravanan Raju , Brittany K Smith , Haiyan Zhao , James Brett Case , Emma S Winkler , Bradley M Whitener , Lindsay Droit , Ishmael D Aziati , Traci L Bricker , Astha Joshi , Pei-Yong Shi , Adrian Creanga , Amarendra Pegu , Scott A Handley , David Wang , Adrianus C M Boon , James E Crowe , Sean P J Whelan , Daved H Fremont , Michael S Diamond

Concordance of immunological events between intrarectal and intravenous SHIVAD8-EO infection when assessed by Fiebig-equivalent staging.

The Journal of clinical investigation
Avec: Joana Dias , Giulia Fabozzi , Kylie March , Mangaiarkarasi Asokan , Cassandra G Almasri , Jonathan Fintzi , Wanwisa Promsote , Yoshiaki Nishimura , John-Paul Todd , Jeffrey D Lifson , Malcolm A Martin , Lucio Gama , Constantinos Petrovas , Amarendra Pegu , John R Mascola , Richard A Koup

TLR7 agonist, N6-LS and PGT121 delayed viral rebound in SHIV-infected macaques after antiretroviral therapy interruption.

PLoS pathogens
Avec: Denise C Hsu , Alexandra Schuetz , Rawiwan Imerbsin , Decha Silsorn , Amarendra Pegu , Dutsadee Inthawong , Jumpol Sopanaporn , Pornsuk Visudhiphan , Weerawan Chuenarom , Boot Keawboon , Wei Shi , Merlin L Robb , John R Mascola , Romas Geleziunas , Richard A Koup , Dan H Barouch , Nelson L Michael , Sandhya Vasan

Primary exposure to SARS-CoV-2 variants elicits convergent epitope specificities, immunoglobulin V gene usage and public B cell clones.

bioRxiv : the preprint server for biology
Avec: Noemia S Lima , Maryam Musayev , Timothy S Johnston , Danielle A Wagner , Amy R Henry , Lingshu Wang , Eun Sung Yang , Yi Zhang , Kevina Birungi , Walker P Black , Sijy O'Dell , Stephen D Schmidt , Damee Moon , Cynthia G Lorang , Bingchun Zhao , Man Chen , Kristin L Boswell , Jesmine Roberts-Torres , Rachel L Davis , Lowrey Peyton , Sandeep R Narpala , Sarah O'Connell , Jennifer Wang , Alexander Schrager , Chloe Adrienna Talana , Kwanyee Leung , Wei Shi , Rawan Khashab , Asaf Biber , Tal Zilberman , Joshua Rhein , Sara Vetter , Afeefa Ahmed , Laura Novik , Alicia Widge , Ingelise Gordon , Mercy Guech , I-Ting Teng , Emily Phung , Tracy J Ruckwardt , Amarendra Pegu , John Misasi , Nicole A Doria-Rose , Martin Gaudinski , Richard A Koup , Peter D Kwong , Adrian B McDermott , Sharon Amit , Timothy W Schacker , Itzchak Levy , John R Mascola , Nancy J Sullivan , Chaim A Schramm , Daniel C Douek

Anatomic Distribution of Intravenously Injected IgG Takes Approximately 1 Week to Achieve Stratum Corneum Saturation in Vaginal Tissues.

Journal of immunology (Baltimore, Md. : 1950)
Avec: Ann M Carias , Jeffrey R Schneider , Patrick Madden , Ramon Lorenzo-Redondo , Mariluz Araínga , Amarendra Pegu , Gianguido C Cianci , Danijela Maric , Francois Villinger , John R Mascola , Ronald S Veazey , Thomas J Hope

Durability of mRNA-1273 vaccine-induced antibodies against SARS-CoV-2 variants.

Science (New York, N.Y.)
Avec: Amarendra Pegu , Sarah E O'Connell , Stephen D Schmidt , Sijy O'Dell , Chloe A Talana , Lilin Lai , Jim Albert , Evan Anderson , Hamilton Bennett , Kizzmekia S Corbett , Britta Flach , Lisa Jackson , Brett Leav , Julie E Ledgerwood , Catherine J Luke , Mat Makowski , Martha C Nason , Paul C Roberts , Mario Roederer , Paulina A Rebolledo , Christina A Rostad , Nadine G Rouphael , Wei Shi , Lingshu Wang , Alicia T Widge , Eun Sung Yang , Auteur inconnu , John H Beigel , Barney S Graham , John R Mascola , Mehul S Suthar , Adrian B McDermott , Nicole A Doria-Rose , Jae Arega , John H Beigel , Wendy Buchanan , Mohammed Elsafy , Binh Hoang , Rebecca Lampley , Aparna Kolhekar , Hyung Koo , Catherine Luke , Mamodikoe Makhene , Seema Nayak , Rhonda Pikaart-Tautges , Paul C Roberts , Janie Russell , Elisa Sindall , Jim Albert , Pratap Kunwar , Mat Makowski , Evan J Anderson , Amer Bechnak , Mary Bower , Andres F Camacho-Gonzalez , Matthew Collins , Ana Drobeniuc , Venkata Viswanadh Edara , Srilatha Edupuganti , Katharine Floyd , Theda Gibson , Cassie M Grimsley Ackerley , Brandi Johnson , Satoshi Kamidani , Carol Kao , Colleen Kelley , Lilin Lai , Hollie Macenczak , Michele Paine McCullough , Etza Peters , Varun K Phadke , Paulina A Rebolledo , Christina A Rostad , Nadine Rouphael , Erin Scherer , Amy Sherman , Kathy Stephens , Mehul S Suthar , Mehgan Teherani , Jessica Traenkner , Juton Winston , Inci Yildirim , Lee Barr , Joyce Benoit , Barbara Carste , Joe Choe , Maya Dunstan , Roxanne Erolin , Jana Ffitch , Colin Fields , Lisa A Jackson , Erika Kiniry , Susan Lasicka , Stella Lee , Matthew Nguyen , Stephanie Pimienta , Janice Suyehira , Michael Witte , Hamilton Bennett , Nedim Emil Altaras , Andrea Carfi , Marjorie Hurley , Brett Leav , Rolando Pajon , Wellington Sun , Tal Zaks , Rhea N Coler , Sasha E Larsen , Kathleen M Neuzil , Lisa C Lindesmith , David R Martinez , Jennifer Munt , Michael Mallory , Caitlin Edwards , Ralph S Baric , Nina M Berkowitz , Eli A Boritz , Kevin Carlton , Kizzmekia S Corbett , Pamela Costner , Adrian Creanga , Nicole A Doria-Rose , Daniel C Douek , Britta Flach , Martin Gaudinski , Ingelise Gordon , Barney S Graham , LaSonji Holman , Julie E Ledgerwood , Kwanyee Leung , Bob C Lin , Mark K Louder , John R Mascola , Adrian B McDermott , Kaitlyn M Morabito , Laura Novik , Sarah O'Connell , Sijy O'Dell , Marcelino Padilla , Amarendra Pegu , Stephen D Schmidt , Wei Shi , Phillip A Swanson , Chloe A Talana , Lingshu Wang , Alicia T Widge , Eun Sung Yang , Yi Zhang , James D Chappell , Mark R Denison , Tia Hughes , Xiaotao Lu , Andrea J Pruijssers , Laura J Stevens , Christine M Posavad , Michael Gale , Vineet Menachery , Pei-Yong Shi

Blocking α

Science translational medicine
Avec: Ines Frank , Mariasole Cigoli , Muhammad S Arif , Marissa D Fahlberg , Stephanie Maldonado , Giulia Calenda , Amarendra Pegu , Eun Sung Yang , Reda Rawi , Gwo-Yu Chuang , Hui Geng , Cuiping Liu , Tongqing Zhou , Peter D Kwong , James Arthos , Claudia Cicala , Brooke F Grasperge , James L Blanchard , Agegnehu Gettie , Christine M Fennessey , Brandon F Keele , Monica Vaccari , Thomas J Hope , Anthony S Fauci , John R Mascola , Elena Martinelli

A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention.

mAbs
Avec: Young D Kwon , Mangaiarkarasi Asokan , Jason Gorman , Baoshan Zhang , Qingbo Liu , Mark K Louder , Bob C Lin , Krisha McKee , Amarendra Pegu , Raffaello Verardi , Eun Sung Yang , Vrc Production Program , Kevin Carlton , Nicole A Doria-Rose , Paolo Lusso , John R Mascola , Peter D Kwong

Broadly neutralizing antibodies target the coronavirus fusion peptide.

Science (New York, N.Y.)
Avec: Cherrelle Dacon , Courtney Tucker , Linghang Peng , Chang-Chun D Lee , Ting-Hui Lin , Meng Yuan , Yu Cong , Lingshu Wang , Lauren Purser , Jazmean K Williams , Chul-Woo Pyo , Ivan Kosik , Zhe Hu , Ming Zhao , Divya Mohan , Andrew J R Cooper , Mary Peterson , Jeff Skinner , Saurabh Dixit , Erin Kollins , Louis Huzella , Donna Perry , Russell Byrum , Sanae Lembirik , David Drawbaugh , Brett Eaton , Yi Zhang , Eun Sung Yang , Man Chen , Kwanyee Leung , Rona S Weinberg , Amarendra Pegu , Daniel E Geraghty , Edgar Davidson , Iyadh Douagi , Susan Moir , Jonathan W Yewdell , Connie Schmaljohn , Peter D Crompton , Michael R Holbrook , David Nemazee , John R Mascola , Ian A Wilson , Joshua Tan

Phase 1 trial evaluating safety and pharmacokinetics of HIV-1 broadly neutralizing mAbs 10E8VLS and VRC07-523LS.

JCI insight
Avec: Seemal F Awan , Amarendra Pegu , Larisa Strom , Cristina A Carter , Cynthia S Hendel , LaSonji A Holman , Pamela J Costner , Olga Trofymenko , Renunda Dyer , Ingelise J Gordon , Ro Shauna S Rothwell , Somia P Hickman , Michelle Conan-Cibotti , Nicole A Doria-Rose , Bob C Lin , Sarah O'Connell , Sandeep R Narpala , Cassandra G Almasri , Cuiping Liu , Sungyoul Ko , Young D Kwon , Aryan M Namboodiri , Janardan P Pandey , Frank J Arnold , Kevin Carlton , Jason G Gall , Peter D Kwong , Edmund V Capparelli , Robert T Bailer , Adrian B McDermott , Grace L Chen , Richard A Koup , John R Mascola , Emily E Coates , Julie E Ledgerwood , Martin R Gaudinski , Auteur inconnu

Trispecific antibody targeting HIV-1 and T cells activates and eliminates latently-infected cells in HIV/SHIV infections.

Nature communications
Avec: Wanwisa Promsote , Ling Xu , Jason Hataye , Giulia Fabozzi , Kylie March , Cassandra G Almasri , Megan E DeMouth , Sarah E Lovelace , Chloe Adrienna Talana , Nicole A Doria-Rose , Krisha McKee , Sabrina Helmold Hait , Joseph P Casazza , David Ambrozak , Jochen Beninga , Ercole Rao , Norbert Furtmann , Joerg Birkenfeld , Elizabeth McCarthy , John-Paul Todd , Constantinos Petrovas , Mark Connors , Andrew T Hebert , Jeremy Beck , Junqing Shen , Bailin Zhang , Mikhail Levit , Ronnie R Wei , Zhi-Yong Yang , Amarendra Pegu , John R Mascola , Gary J Nabel , Richard A Koup

A multispecific antibody against SARS-CoV-2 prevents immune escape in vitro and confers prophylactic protection in vivo.

Science translational medicine
Avec: John Misasi , Ronnie R Wei , Lingshu Wang , Amarendra Pegu , Chih-Jen Wei , Olamide K Oloniniyi , Tongqing Zhou , Juan I Moliva , Bingchun Zhao , Misook Choe , Eun Sung Yang , Yi Zhang , Marika Boruszczak , Man Chen , Kwanyee Leung , Juan Li , Zhi-Yong Yang , Hanne Andersen , Kevin Carlton , Sucheta Godbole , Darcy R Harris , Amy R Henry , Vera B Ivleva , Q Paula Lei , Cuiping Liu , Lindsay Longobardi , Jonah S Merriam , Danielle Nase , Adam S Olia , Laurent Pessaint , Maciel Porto , Wei Shi , Shannon M Wallace , Jeremy J Wolff , Daniel C Douek , Mehul S Suthar , Jason G Gall , Richard A Koup , Peter D Kwong , John R Mascola , Gary J Nabel , Nancy J Sullivan

Removal of variable domain

mAbs
Avec: Gwo-Yu Chuang , Mangaiarkarasi Asokan , Vera B Ivleva , Amarendra Pegu , Eun Sung Yang , Baoshan Zhang , Rajoshi Chaudhuri , Hui Geng , Bob C Lin , Mark K Louder , Krisha McKee , Sijy O'Dell , Hairong Wang , Tongqing Zhou , Nicole A Doria-Rose , Lisa A Kueltzo , Q Paula Lei , John R Mascola , Peter D Kwong

Antibodies with potent and broad neutralizing activity against antigenically diverse and highly transmissible SARS-CoV-2 variants.

bioRxiv : the preprint server for biology
Avec: Lingshu Wang , Tongqing Zhou , Yi Zhang , Eun Sung Yang , Chaim A Schramm , Wei Shi , Amarendra Pegu , Olamide K Oloninyi , Amy Ransier , Samuel Darko , Sandeep R Narpala , Christian Hatcher , David R Martinez , Yaroslav Tsybovsky , Emily Phung , Olubukola M Abiona , Evan M Cale , Lauren A Chang , Kizzmekia S Corbett , Anthony T DiPiazza , Ingelise J Gordon , Kwanyee Leung , Tracy Liu , Rosemarie D Mason , Alexandra Nazzari , Laura Novik , Adam S Olia , Nicole A Doria-Rose , Tyler Stephens , Christopher D Stringham , Chloe Adrienna Talana , I-Ting Teng , Danielle Wagner , Alicia T Widge , Baoshan Zhang , Mario Roederer , Julie E Ledgerwood , Tracy J Ruckwardt , Martin R Gaudinski , Ralph S Baric , Barney S Graham , Adrian B McDermott , Daniel C Douek , Peter D Kwong , John R Mascola , Nancy J Sullivan , John Misasi

Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants.

bioRxiv : the preprint server for biology
Avec: Hyeseon Cho , Kristina Kay Gonzales-Wartz , Deli Huang , Meng Yuan , Mary Peterson , Janie Liang , Nathan Beutler , Jonathan L Torres , Yu Cong , Elena Postnikova , Sandhya Bangaru , Chloe Adrienna Talana , Wei Shi , Eun Sung Yang , Yi Zhang , Kwanyee Leung , Lingshu Wang , Linghang Peng , Jeff Skinner , Shanping Li , Nicholas C Wu , Hejun Liu , Cherrelle Dacon , Thomas Moyer , Melanie Cohen , Ming Zhao , F Eun-Hyung Lee , Rona S Weinberg , Iyadh Douagi , Robin Gross , Connie Schmaljohn , Amarendra Pegu , John R Mascola , Michael Holbrook , David Nemazee , Thomas F Rogers , Andrew B Ward , Ian A Wilson , Peter D Crompton , Joshua Tan

Safety and pharmacokinetics of broadly neutralising human monoclonal antibody VRC07-523LS in healthy adults: a phase 1 dose-escalation clinical trial.

The lancet. HIV
Avec: Martin R Gaudinski , Katherine V Houser , Nicole A Doria-Rose , Grace L Chen , Ro Shauna S Rothwell , Nina Berkowitz , Pamela Costner , LaSonji A Holman , Ingelise J Gordon , Cynthia S Hendel , Florence Kaltovich , Michelle Conan-Cibotti , Margarita Gomez Lorenzo , Cristina Carter , Sandra Sitar , Kevin Carlton , Jason Gall , Carolyn Laurencot , Bob C Lin , Robert T Bailer , Adrian B McDermott , Sung-Youl Ko , Amarendra Pegu , Young D Kwon , Peter D Kwong , Aryan M Namboodiri , Janardan P Pandey , Richard Schwartz , Frank Arnold , Zonghui Hu , Lily Zhang , Yunda Huang , Richard A Koup , Edmund V Capparelli , Barney S Graham , John R Mascola , Julie E Ledgerwood , Auteur inconnu

Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity.

Nature communications
Avec: Mariya B Shapiro , Tracy Cheever , Delphine C Malherbe , Shilpi Pandey , Jason Reed , Eun Sung Yang , Keyun Wang , Amarendra Pegu , Xuejun Chen , Don Siess , David Burke , Heidi Henderson , Rebecca Lewinsohn , Miranda Fischer , Jeffrey J Stanton , Michael K Axthelm , Christoph Kahl , Byung Park , Anne D Lewis , Jonah B Sacha , John R Mascola , Ann J Hessell , Nancy L Haigwood

Infection and vaccine-induced neutralizing antibody responses to the SARS-CoV-2 B.1.617.1 variant.

bioRxiv : the preprint server for biology
Avec: Venkata-Viswanadh Edara , Lilin Lai , Malaya K Sahoo , Katharine Floyd , Mamdouh Sibai , Daniel Solis , Maria W Flowers , Laila Hussaini , Caroline Rose Ciric , Sarah Bechnack , Kathy Stephens , Elham Bayat Mokhtari , Prakriti Mudvari , Adrian Creanga , Amarendra Pegu , Alexandrine Derrien-Colemyn , Amy R Henry , Matthew Gagne , Barney S Graham , Jens Wrammert , Daniel C Douek , Eli Boritz , Benjamin A Pinsky , Mehul S Suthar

Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern.

Science translational medicine
Avec: Hyeseon Cho , Kristina Kay Gonzales-Wartz , Deli Huang , Meng Yuan , Mary Peterson , Janie Liang , Nathan Beutler , Jonathan L Torres , Yu Cong , Elena Postnikova , Sandhya Bangaru , Chloe Adrienna Talana , Wei Shi , Eun Sung Yang , Yi Zhang , Kwanyee Leung , Lingshu Wang , Linghang Peng , Jeff Skinner , Shanping Li , Nicholas C Wu , Hejun Liu , Cherrelle Dacon , Thomas Moyer , Melanie Cohen , Ming Zhao , Frances Eun-Hyung Lee , Rona S Weinberg , Iyadh Douagi , Robin Gross , Connie Schmaljohn , Amarendra Pegu , John R Mascola , Michael Holbrook , David Nemazee , Thomas F Rogers , Andrew B Ward , Ian A Wilson , Peter D Crompton , Joshua Tan

Vaccine-elicited murine antibody WS6 neutralizes diverse beta-coronaviruses by recognizing a helical stem supersite of vulnerability.

bioRxiv : the preprint server for biology
Avec: Wei Shi , Lingshu Wang , Tongqing Zhou , Mallika Sastry , Eun Sung Yang , Yi Zhang , Man Chen , Xuejun Chen , Misook Choe , Adrian Creanga , Kwan Leung , Adam S Olia , Amarendra Pegu , Reda Rawi , Chen-Hsiang Shen , Erik-Stephane D Stancofski , Chloe Adrienna Talana , I-Ting Teng , Shuishu Wang , Kizzmekia S Corbett , Yaroslav Tsybovsky , John R Mascola , Peter D Kwong

HIV broadly neutralizing antibody escapability drives the therapeutic efficacy of vectored immunotherapy.

bioRxiv : the preprint server for biology
Avec: Nicolas M S Galvez , Yi Cao , Adam D Nitido , Cailin E Deal , Christine L Boutros , Scott W MacDonald , Yentli E Soto Albrecht , Evan C Lam , Maegan L Sheehan , Dylan Parsons , Allen Z Lin , Martin J Deymier , Jacqueline M Brady , Benjamin Moon , Christopher B Bullock , Serah Tanno , Amarendra Pegu , Xuejun Chen , Cuiping Liu , Richard A Koup , John R Mascola , Vladimir D Vrbanac , Daniel Lingwood , Alejandro B Balazs

Anti-viral efficacy of a next-generation CD4-binding site bNAb in SHIV-infected animals in the absence of anti-drug antibody responses.

iScience
Avec: Sarah E Lovelace , Sabrina Helmold Hait , Eun Sung Yang , Madison L Fox , Cuiping Liu , Misook Choe , Xuejun Chen , Elizabeth McCarthy , John-Paul Todd , Ruth A Woodward , Richard A Koup , John R Mascola , Amarendra Pegu

A multispecific antibody prevents immune escape and confers pan-SARS-CoV-2 neutralization.

bioRxiv : the preprint server for biology
Avec: John Misasi , Ronnie R Wei , Lingshu Wang , Amarendra Pegu , Chih-Jen Wei , Olamide K Oloniniyi , Tongqing Zhou , Juan I Moliva , Bingchun Zhao , Misook Choe , Eun Sung Yang , Yi Zhang , Marika Boruszczak , Man Chen , Kwan Leung , Juan Li , Zhi-Yong Yang , Hanne Andersen , Kevin Carlton , Sucheta Godbole , Darcy R Harris , Amy R Henry , Vera B Ivleva , Paula Lei , Cuiping Liu , Lindsay Longobardi , Jonah S Merriam , Danielle Nase , Adam S Olia , Laurent Pessaint , Maciel Porto , Wei Shi , Jeremy J Wolff , Daniel C Douek , Mehul S Suthar , Jason Gall , Richard A Koup , Peter D Kwong , John R Mascola , Gary J Nabel , Nancy J Sullivan

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John R Mascola 37 collaborations
Eun Sung Yang 25 collaborations
Nicole A Doria-Rose 19 collaborations
Wei Shi 19 collaborations
Peter D Kwong 18 collaborations
Richard A Koup 16 collaborations
Lingshu Wang 16 collaborations
Yi Zhang 14 collaborations
Tongqing Zhou 12 collaborations
Stephen D Schmidt 11 collaborations
Xuejun Chen 11 collaborations
Adrian B McDermott 11 collaborations
Cuiping Liu 11 collaborations
Kwanyee Leung 11 collaborations
Sijy O'Dell 10 collaborations
Misook Choe 10 collaborations
Chloe Adrienna Talana 10 collaborations
Barney S Graham 9 collaborations
Daniel C Douek 9 collaborations
Sarah O'Connell 8 collaborations
Baoshan Zhang 8 collaborations
Kizzmekia S Corbett 8 collaborations
I-Ting Teng 8 collaborations
Julie E Ledgerwood 8 collaborations
Nancy J Sullivan 8 collaborations
Man Chen 8 collaborations
Yaroslav Tsybovsky 7 collaborations
Bob C Lin 7 collaborations
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None None 6 collaborations
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Hyeseon Cho 2 collaborations
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Deli Huang 2 collaborations
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