Annette E Langkilde

Affiliations

Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences , University of Copenhagen , Universitetsparken 2 , 2100 Copenhagen N, Denmark.

Publications (12)

Distinct α-Synuclein:Lipid Co-Structure Complexes Affect Amyloid Nucleation through Fibril Mimetic Behavior.

Biochemistry

Avec: Ersoy Cholak , Saskia Bucciarelli , Katrine Bugge , Nicolai Tidemand Johansen , Bente Vestergaard , Lise Arleth , Birthe B Kragelund , Annette E Langkilde

Recommendations for addressing the translational gap between experimental and clinical research on amyloid diseases.

Journal of translational medicine

Avec: Miriam Solomon , Vito Foderà , Annette Eva Langkilde , Perry Elliott , Fabrizio Tagliavini , Trevor Forsyth , Oxana Klementieva , Vittorio Bellotti

Ligand-induced CaMKIIα hub Trp403 flip, hub domain stacking, and modulation of kinase activity.

Protein science : a publication of the Protein Society

Avec: Dilip Narayanan , Anne Sofie G Larsen , Stine Juul Gauger , Ruth Adafia , Rikke Bartschick Hammershøi , Louise Hamborg , Jesper Bruus-Jensen , Nane Griem-Krey , Christine L Gee , Bente Frølund , Margaret M Stratton , John Kuriyan , Jette Sandholm Kastrup , Annette E Langkilde , Petrine Wellendorph , Sara M Ø Solbak

Structural insights into protein folding, stability and activity using

IUCrJ

Avec: Joao Ramos , Valerie Laux , Michael Haertlein , Elisabetta Boeri Erba , Katherine E McAuley , V Trevor Forsyth , Estelle Mossou , Sine Larsen , Annette E Langkilde

Avidity within the N-terminal anchor drives α-synuclein membrane interaction and insertion.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology

Avec: Ersoy Cholak , Katrine Bugge , Adree Khondker , Kimmie Gauger , Elena Pedraz-Cuesta , Morten Enghave Pedersen , Saskia Bucciarelli , Bente Vestergaard , Stine F Pedersen , Maikel C Rheinstädter , Annette Eva Langkilde , Birthe B Kragelund

Developing Inhibitors of the p47phox-p22phox Protein-Protein Interaction by Fragment-Based Drug Discovery.

Journal of medicinal chemistry

Avec: Sara Marie Øie Solbak , Jie Zang , Dilip Narayanan , Lars Jakobsen Høj , Saskia Bucciarelli , Charlotte Softley , Sebastian Meier , Annette Eva Langkilde , Charlotte Held Gotfredsen , Michael Sattler , Anders Bach

The impact of folding modes and deuteration on the atomic resolution structure of hen egg-white lysozyme.

Acta crystallographica. Section D, Structural biology

Avec: Joao Ramos , Valerie Laux , Michael Haertlein , V Trevor Forsyth , Estelle Mossou , Sine Larsen , Annette E Langkilde

Sleep-controlling neurons are sensitive and vulnerable to multiple forms of α-synuclein: implications for the early appearance of sleeping disorders in α-synucleinopathies.

Cellular and molecular life sciences : CMLS

Avec: Altair B Dos Santos , Line K Skaanning , Siganya Thaneshwaran , Eyd Mikkelsen , Cesar R Romero-Leguizamón , Thomas Skamris , Morten P Kristensen , Annette E Langkilde , Kristi A Kohlmeier

Protein fibrillation from another small angle: Sample preparation and SAXS data collection.

Methods in enzymology

Avec: Bente Vestergaard , Annette Eva Langkilde

The Non-Fibrillating N-Terminal of α-Synuclein Binds and Co-Fibrillates with Heparin.

Biomolecules

Avec: Line K Skaanning , Angelo Santoro , Thomas Skamris , Jacob Hertz Martinsen , Anna Maria D'Ursi , Saskia Bucciarelli , Bente Vestergaard , Katrine Bugge , Annette Eva Langkilde , Birthe B Kragelund

The structural basis of fungal glucuronoyl esterase activity on natural substrates.

Nature communications

Avec: Heidi A Ernst , Caroline Mosbech , Annette E Langkilde , Peter Westh , Anne S Meyer , Jane W Agger , Sine Larsen

Refinement of α-Synuclein Ensembles Against SAXS Data: Comparison of Force Fields and Methods.

Frontiers in molecular biosciences

Avec: Mustapha Carab Ahmed , Line K Skaanning , Alexander Jussupow , Estella A Newcombe , Birthe B Kragelund , Carlo Camilloni , Annette E Langkilde , Kresten Lindorff-Larsen

Réseau de co-auteurs

Annette Eva Langkilde 5 collaborations

Saskia Bucciarelli 4 collaborations

Bente Vestergaard 4 collaborations

Birthe B Kragelund 4 collaborations

Katrine Bugge 3 collaborations

Sine Larsen 3 collaborations

Line K Skaanning 3 collaborations

Ersoy Cholak 2 collaborations

Dilip Narayanan 2 collaborations

Joao Ramos 2 collaborations

Valerie Laux 2 collaborations

Michael Haertlein 2 collaborations

V Trevor Forsyth 2 collaborations

Estelle Mossou 2 collaborations

Thomas Skamris 2 collaborations

Nicolai Tidemand Johansen 1 collaboration

Lise Arleth 1 collaboration

Miriam Solomon 1 collaboration

Vito Foderà 1 collaboration

Perry Elliott 1 collaboration

Fabrizio Tagliavini 1 collaboration

Trevor Forsyth 1 collaboration

Oxana Klementieva 1 collaboration

Vittorio Bellotti 1 collaboration

Anne Sofie G Larsen 1 collaboration

Stine Juul Gauger 1 collaboration

Ruth Adafia 1 collaboration

Rikke Bartschick Hammershøi 1 collaboration

Louise Hamborg 1 collaboration

Jesper Bruus-Jensen 1 collaboration

Nane Griem-Krey 1 collaboration

Christine L Gee 1 collaboration

Bente Frølund 1 collaboration

Margaret M Stratton 1 collaboration

John Kuriyan 1 collaboration

Jette Sandholm Kastrup 1 collaboration

Petrine Wellendorph 1 collaboration

Sara M Ø Solbak 1 collaboration

Elisabetta Boeri Erba 1 collaboration

Katherine E McAuley 1 collaboration

Adree Khondker 1 collaboration

Kimmie Gauger 1 collaboration

Elena Pedraz-Cuesta 1 collaboration

Morten Enghave Pedersen 1 collaboration

Stine F Pedersen 1 collaboration

Maikel C Rheinstädter 1 collaboration

Sara Marie Øie Solbak 1 collaboration

Jie Zang 1 collaboration

Lars Jakobsen Høj 1 collaboration

Charlotte Softley 1 collaboration

Sebastian Meier 1 collaboration

Charlotte Held Gotfredsen 1 collaboration

Michael Sattler 1 collaboration

Anders Bach 1 collaboration

Altair B Dos Santos 1 collaboration

Siganya Thaneshwaran 1 collaboration

Eyd Mikkelsen 1 collaboration

Cesar R Romero-Leguizamón 1 collaboration

Morten P Kristensen 1 collaboration

Kristi A Kohlmeier 1 collaboration

Angelo Santoro 1 collaboration

Jacob Hertz Martinsen 1 collaboration

Anna Maria D'Ursi 1 collaboration

Heidi A Ernst 1 collaboration

Caroline Mosbech 1 collaboration

Peter Westh 1 collaboration

Anne S Meyer 1 collaboration

Jane W Agger 1 collaboration

Mustapha Carab Ahmed 1 collaboration

Alexander Jussupow 1 collaboration

Estella A Newcombe 1 collaboration

Carlo Camilloni 1 collaboration

Kresten Lindorff-Larsen 1 collaboration