Benjamin Tycko

Affiliations

Columbia University Irving Medical Center, Department of Pathology and Cell Biology, New York, NY, USA.

Publications (24)

Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer's Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome.

Journal of Alzheimer's disease : JAD

Avec: Melissa E Petersen , Michael S Rafii , Fan Zhang , James Hall , David Julovich , Beau M Ances , Nicole Schupf , Sharon J Krinsky-McHale , Mark Mapstone , Wayne Silverman , Ira Lott , William Klunk , Elizabeth Head , Brad Christian , Tatiana Foroud , Florence Lai , H Diana Rosas , Shahid Zaman , Mei-Cheng Wang , Benjamin Tycko , Joseph H Lee , Benjamin Handen , Sigan Hartley , Juan Fortea , Sid O'Bryant , Auteur inconnu

R-loop landscapes in the developing human brain are linked to neural differentiation and cell-type specific transcription.

bioRxiv : the preprint server for biology

Avec: Elizabeth A LaMarca , Atsushi Saito , Amara Plaza-Jennings , Sergio Espeso-Gil , Allyse Hellmich , Michael B Fernando , Behnam Javidfar , Will Liao , Molly Estill , Kayla Townsley , Anna Florio , James E Ethridge , Catherine Do , Benjamin Tycko , Li Shen , Atsushi Kamiya , Nadejda M Tsankova , Kristen J Brennand , Schahram Akbarian

Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) study.

Alzheimer's & dementia (Amsterdam, Netherlands)

Avec: Melissa E Petersen , Fan Zhang , Nicole Schupf , Sharon J Krinsky-McHale , James Hall , Mark Mapstone , Amrita Cheema , Wayne Silverman , Ira Lott , Michael S Rafii , Benjamin Handen , William Klunk , Elizabeth Head , Brad Christian , Tatiana Foroud , Florence Lai , H Diana Rosas , Shahid Zaman , Beau M Ances , Mei-Cheng Wang , Benjamin Tycko , Joseph H Lee , Sid O'Bryant , Auteur inconnu

Allele-specific DNA methylation is increased in cancers and its dense mapping in normal plus neoplastic cells increases the yield of disease-associated regulatory SNPs.

Genome biology

Avec: Catherine Do , Emmanuel L P Dumont , Martha Salas , Angelica Castano , Huthayfa Mujahed , Leonel Maldonado , Arunjot Singh , Sonia C DaSilva-Arnold , Govind Bhagat , Soren Lehman , Angela M Christiano , Subha Madhavan , Peter L Nagy , Peter H R Green , Rena Feinman , Cornelia Trimble , Nicholas P Illsley , Karen Marder , Lawrence Honig , Catherine Monk , Andre Goy , Kar Chow , Samuel Goldlust , George Kaptain , David Siegel , Benjamin Tycko

Random field modeling of multi-trait multi-locus association for detecting methylation quantitative trait loci.

Bioinformatics (Oxford, England)

Avec: Chen Lyu , Manyan Huang , Nianjun Liu , Zhongxue Chen , Philip J Lupo , Benjamin Tycko , John S Witte , Charlotte A Hobbs , Ming Li

PHLDA2-mediated phosphatidic acid peroxidation triggers a distinct ferroptotic response during tumor suppression.

Cell metabolism

Avec: Xin Yang , Zhe Wang , Svetlana N Samovich , Alexander A Kapralov , Andrew A Amoscato , Vladimir A Tyurin , Haider H Dar , Zhiming Li , Shoufu Duan , Ning Kon , Delin Chen , Benjamin Tycko , Zhiguo Zhang , Xuejun Jiang , Hülya Bayir , Brent R Stockwell , Valerian E Kagan , Wei Gu

Epigenetic changes regulating the epithelial-mesenchymal transition in human trophoblast differentiation.

bioRxiv : the preprint server for biology

Avec: William E Ackerman , Mauricio M Rigo , Sonia C DaSilva-Arnold , Catherine Do , Mariam Tariq , Martha Salas , Angelica Castano , Stacy Zamudio , Benjamin Tycko , Nicholas P Illsley

Distinct epigenetic profiles in children with perinatally-acquired HIV on antiretroviral therapy.

Scientific reports

Avec: Stephanie Shiau , Renate Strehlau , Shuang Wang , Avy Violari , Catherine Do , Faeezah Patel , Afaaf Liberty , Izabela Krupska , Stephen M Arpadi , Marc Foca , Ashraf Coovadia , Elaine J Abrams , Benjamin Tycko , Mary Beth Terry , Louise Kuhn

Correction: Genetic variants influence on the placenta regulatory landscape.

PLoS genetics

Avec: Fabien Delahaye , Catherine Do , Yu Kong , Remi Ashkar , Martha Salas , Ben Tycko , Ronald Wapner , Francine Hughes

CloudASM: an ultra-efficient cloud-based pipeline for mapping allele-specific DNA methylation.

Bioinformatics (Oxford, England)

Avec: Emmanuel L P Dumont , Benjamin Tycko , Catherine Do

DNA methylation patterns in T lymphocytes are generally stable in human pregnancies but CD3 methylation is associated with perinatal psychiatric symptoms.

Brain, behavior, & immunity - health

Avec: Thalia K Robakis , Seonjoo Lee , Elizabeth Werner , Grace Liu , Melissa Miller , Dennis Wylie , Frances A Champagne , Martha Salas , Catherine Do , Benjamin Tycko , Catherine Monk

Detecting methylation quantitative trait loci using a methylation random field method.

Briefings in bioinformatics

Avec: Chen Lyu , Manyan Huang , Nianjun Liu , Zhongxue Chen , Philip J Lupo , Benjamin Tycko , John S Witte , Charlotte A Hobbs , Ming Li

Maternal high BMI: Sex-dimorphic alterations in maternal and offspring stress indices.

Psychoneuroendocrinology

Avec: Sameera Abuaish , Vanessa Babineau , Seonjoo Lee , Benjamin Tycko , Frances A Champagne , Elizabeth Werner , Catherine Monk

Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Kate Walsh , Clare A McCormack , Rachel Webster , Anita Pinto , Seonjoo Lee , Tianshu Feng , H Sloan Krakovsky , Sinclaire M O'Grady , Benjamin Tycko , Frances A Champagne , Elizabeth A Werner , Grace Liu , Catherine Monk

Genetic and epigenetic pathways in Down syndrome: Insights to the brain and immune system from humans and mouse models.

Progress in brain research

Avec: Y Eugene Yu , Zhuo Xing , Catherine Do , Annie Pao , Eun Joon Lee , Sharon Krinsky-McHale , Wayne Silverman , Nicole Schupf , Benjamin Tycko

Mapping methylation quantitative trait loci in cardiac tissues nominates risk loci and biological pathways in congenital heart disease.

BMC genomic data

Avec: Ming Li , Chen Lyu , Manyan Huang , Catherine Do , Benjamin Tycko , Philip J Lupo , Stewart L MacLeod , Christopher E Randolph , Nianjun Liu , John S Witte , Charlotte A Hobbs

Mechanistic Analysis of Age-Related Clinical Manifestations in Down Syndrome.

Frontiers in aging neuroscience

Avec: Xu-Qiao Chen , Zhuo Xing , Quang-Di Chen , Richard J Salvi , Xuming Zhang , Benjamin Tycko , William C Mobley , Y Eugene Yu

The Association between Sex and Risk of Alzheimer's Disease in Adults with Down Syndrome.

Journal of clinical medicine

Avec: Pooja Girish Mhatre , Joseph H Lee , Deborah Pang , Warren B Zigman , Benjamin Tycko , Sharon J Krinsky-McHale , Yuchen Yang , Wayne Silverman , Nicole Schupf

Epigenetic Silencing of BMP6 by the SIN3A-HDAC1/2 Repressor Complex Drives Melanoma Metastasis via FAM83G/PAWS1.

Molecular cancer research : MCR

Avec: Dongkook Min , Jaemin Byun , Eun-Joon Lee , Abdul A Khan , Christina Liu , Oliver Loudig , Wei Hu , Yong Zhao , Meenhard Herlyn , Benjamin Tycko , Phillip A Cole , Byungwoo Ryu

Stress and DNA Methylation of Blood Leukocytes among Pregnant Latina Women.

Epigenomes

Avec: Veronica Barcelona , Sameera Abuaish , Seonjoo Lee , Sarah Harkins , Ashlie Butler , Benjamin Tycko , Andrea A Baccarelli , Kate Walsh , Catherine E Monk

A DNA Hypomethylating Drug Alters the Tumor Microenvironment and Improves the Effectiveness of Immune Checkpoint Inhibitors in a Mouse Model of Pancreatic Cancer.

Cancer research

Avec: Tamas A Gonda , Jarwei Fang , Martha Salas , Catherine Do , Emily Hsu , Anna Zhukovskaya , Ariel Siegel , Ryota Takahashi , Zoila A Lopez-Bujanda , Charles G Drake , Gulam A Manji , Timothy C Wang , Kenneth P Olive , Benjamin Tycko

Sex differences in the associations of placental epigenetic aging with fetal growth.

Aging

Avec: Fasil Tekola-Ayele , Tsegaselassie Workalemahu , Gezahegn Gorfu , Deepika Shrestha , Benjamin Tycko , Ronald Wapner , Cuilin Zhang , Germaine M Buck Louis

Inhibition of NF-κB-Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma.

Cancer research

Avec: Grazia Ambrosini , Catherine Do , Benjamin Tycko , Ronald B Realubit , Charles Karan , Elgilda Musi , Richard D Carvajal , Vivian Chua , Andrew E Aplin , Gary K Schwartz

Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome.

Human molecular genetics

Avec: Zhuo Xing , Yichen Li , Eduardo Cortes-Gomez , Xiaoling Jiang , Shuang Gao , Annie Pao , Jidong Shan , Yinghui Song , Amanda Perez , Tao Yu , Max R Highsmith , Frimpong Boadu , Jeffrey M Conroy , Prashant K Singh , Andrei V Bakin , Jianlin Cheng , Zhijun Duan , Jianmin Wang , Song Liu , Benjamin Tycko , Y Eugene Yu

Réseau de co-auteurs

Catherine Do 11 collaborations

Martha Salas 5 collaborations

Nicole Schupf 4 collaborations

Wayne Silverman 4 collaborations

Catherine Monk 4 collaborations

Seonjoo Lee 4 collaborations

Sharon J Krinsky-McHale 3 collaborations

Joseph H Lee 3 collaborations

Chen Lyu 3 collaborations

Manyan Huang 3 collaborations

Nianjun Liu 3 collaborations

Philip J Lupo 3 collaborations

John S Witte 3 collaborations

Charlotte A Hobbs 3 collaborations

Ming Li 3 collaborations

Frances A Champagne 3 collaborations

Y Eugene Yu 3 collaborations

Zhuo Xing 3 collaborations

Melissa E Petersen 2 collaborations

Michael S Rafii 2 collaborations

Fan Zhang 2 collaborations

James Hall 2 collaborations

Beau M Ances 2 collaborations

Mark Mapstone 2 collaborations

Ira Lott 2 collaborations

William Klunk 2 collaborations

Elizabeth Head 2 collaborations

Brad Christian 2 collaborations

Tatiana Foroud 2 collaborations

Florence Lai 2 collaborations

H Diana Rosas 2 collaborations

Shahid Zaman 2 collaborations

Mei-Cheng Wang 2 collaborations

Benjamin Handen 2 collaborations

Sid O'Bryant 2 collaborations

None None 2 collaborations

Emmanuel L P Dumont 2 collaborations

Angelica Castano 2 collaborations

Sonia C DaSilva-Arnold 2 collaborations

Nicholas P Illsley 2 collaborations

Zhongxue Chen 2 collaborations

Ronald Wapner 2 collaborations

Elizabeth Werner 2 collaborations

Grace Liu 2 collaborations

Sameera Abuaish 2 collaborations

Kate Walsh 2 collaborations

Annie Pao 2 collaborations

David Julovich 1 collaboration

Sigan Hartley 1 collaboration

Juan Fortea 1 collaboration

Elizabeth A LaMarca 1 collaboration

Atsushi Saito 1 collaboration

Amara Plaza-Jennings 1 collaboration

Sergio Espeso-Gil 1 collaboration

Allyse Hellmich 1 collaboration

Michael B Fernando 1 collaboration

Behnam Javidfar 1 collaboration

Will Liao 1 collaboration

Molly Estill 1 collaboration

Kayla Townsley 1 collaboration

Anna Florio 1 collaboration

James E Ethridge 1 collaboration

Li Shen 1 collaboration

Atsushi Kamiya 1 collaboration

Nadejda M Tsankova 1 collaboration

Kristen J Brennand 1 collaboration

Schahram Akbarian 1 collaboration

Amrita Cheema 1 collaboration

Huthayfa Mujahed 1 collaboration

Leonel Maldonado 1 collaboration

Arunjot Singh 1 collaboration

Govind Bhagat 1 collaboration

Soren Lehman 1 collaboration

Angela M Christiano 1 collaboration

Subha Madhavan 1 collaboration

Peter L Nagy 1 collaboration

Peter H R Green 1 collaboration

Rena Feinman 1 collaboration

Cornelia Trimble 1 collaboration

Karen Marder 1 collaboration

Lawrence Honig 1 collaboration

Andre Goy 1 collaboration

Kar Chow 1 collaboration

Samuel Goldlust 1 collaboration

George Kaptain 1 collaboration

David Siegel 1 collaboration

Xin Yang 1 collaboration

Zhe Wang 1 collaboration

Svetlana N Samovich 1 collaboration

Alexander A Kapralov 1 collaboration

Andrew A Amoscato 1 collaboration

Vladimir A Tyurin 1 collaboration

Haider H Dar 1 collaboration

Zhiming Li 1 collaboration

Shoufu Duan 1 collaboration

Ning Kon 1 collaboration

Delin Chen 1 collaboration

Zhiguo Zhang 1 collaboration

Xuejun Jiang 1 collaboration

Hülya Bayir 1 collaboration

Brent R Stockwell 1 collaboration

Valerian E Kagan 1 collaboration

Wei Gu 1 collaboration

William E Ackerman 1 collaboration

Mauricio M Rigo 1 collaboration

Mariam Tariq 1 collaboration

Stacy Zamudio 1 collaboration

Stephanie Shiau 1 collaboration

Renate Strehlau 1 collaboration

Shuang Wang 1 collaboration

Avy Violari 1 collaboration

Faeezah Patel 1 collaboration

Afaaf Liberty 1 collaboration

Izabela Krupska 1 collaboration

Stephen M Arpadi 1 collaboration

Marc Foca 1 collaboration

Ashraf Coovadia 1 collaboration

Elaine J Abrams 1 collaboration

Mary Beth Terry 1 collaboration

Louise Kuhn 1 collaboration

Fabien Delahaye 1 collaboration

Yu Kong 1 collaboration

Remi Ashkar 1 collaboration

Ben Tycko 1 collaboration

Francine Hughes 1 collaboration

Thalia K Robakis 1 collaboration

Melissa Miller 1 collaboration

Dennis Wylie 1 collaboration

Vanessa Babineau 1 collaboration

Clare A McCormack 1 collaboration

Rachel Webster 1 collaboration

Anita Pinto 1 collaboration

Tianshu Feng 1 collaboration

H Sloan Krakovsky 1 collaboration

Sinclaire M O'Grady 1 collaboration

Elizabeth A Werner 1 collaboration

Eun Joon Lee 1 collaboration

Sharon Krinsky-McHale 1 collaboration

Stewart L MacLeod 1 collaboration

Christopher E Randolph 1 collaboration

Xu-Qiao Chen 1 collaboration

Quang-Di Chen 1 collaboration

Richard J Salvi 1 collaboration

Xuming Zhang 1 collaboration

William C Mobley 1 collaboration

Pooja Girish Mhatre 1 collaboration

Deborah Pang 1 collaboration

Warren B Zigman 1 collaboration

Yuchen Yang 1 collaboration

Dongkook Min 1 collaboration

Jaemin Byun 1 collaboration

Eun-Joon Lee 1 collaboration

Abdul A Khan 1 collaboration

Christina Liu 1 collaboration

Oliver Loudig 1 collaboration

Wei Hu 1 collaboration

Yong Zhao 1 collaboration

Meenhard Herlyn 1 collaboration

Phillip A Cole 1 collaboration

Byungwoo Ryu 1 collaboration

Veronica Barcelona 1 collaboration

Sarah Harkins 1 collaboration

Ashlie Butler 1 collaboration

Andrea A Baccarelli 1 collaboration

Catherine E Monk 1 collaboration

Tamas A Gonda 1 collaboration

Jarwei Fang 1 collaboration

Emily Hsu 1 collaboration

Anna Zhukovskaya 1 collaboration

Ariel Siegel 1 collaboration

Ryota Takahashi 1 collaboration

Zoila A Lopez-Bujanda 1 collaboration

Charles G Drake 1 collaboration

Gulam A Manji 1 collaboration

Timothy C Wang 1 collaboration

Kenneth P Olive 1 collaboration

Fasil Tekola-Ayele 1 collaboration

Tsegaselassie Workalemahu 1 collaboration

Gezahegn Gorfu 1 collaboration

Deepika Shrestha 1 collaboration

Cuilin Zhang 1 collaboration

Germaine M Buck Louis 1 collaboration

Grazia Ambrosini 1 collaboration

Ronald B Realubit 1 collaboration

Charles Karan 1 collaboration

Elgilda Musi 1 collaboration

Richard D Carvajal 1 collaboration

Vivian Chua 1 collaboration

Andrew E Aplin 1 collaboration

Gary K Schwartz 1 collaboration

Yichen Li 1 collaboration

Eduardo Cortes-Gomez 1 collaboration

Xiaoling Jiang 1 collaboration

Shuang Gao 1 collaboration

Jidong Shan 1 collaboration

Yinghui Song 1 collaboration

Amanda Perez 1 collaboration

Tao Yu 1 collaboration

Max R Highsmith 1 collaboration

Frimpong Boadu 1 collaboration

Jeffrey M Conroy 1 collaboration

Prashant K Singh 1 collaboration

Andrei V Bakin 1 collaboration

Jianlin Cheng 1 collaboration

Zhijun Duan 1 collaboration

Jianmin Wang 1 collaboration

Song Liu 1 collaboration