Benjamin Uzan

Affiliations

Unité Mixte de Recherche 967 (UMR 967), INSERM-Commissariat à l'Énergie Atomique et aux Énergies Alternatives (CEA)/Direction de la Recherche Fondamentale (DRF)/Institut de Biologie François Jacob (IBFJ)/Institut de Radiobiologie Cellulaire et Moléculaire (IRCM)/Laboratoire des cellules Souches Hématopoïétiques et des Leucémies (LSHL)-Université Paris-Diderot-Université Paris-Sud, Fontenay-aux-Roses, France.

Publications (9)

Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers.

Blood

Avec: Alexandre Fagnan , Frederik Otzen Bagger , Maria-Riera Piqué-Borràs , Cathy Ignacimouttou , Alexis Caulier , Cécile K Lopez , Elie Robert , Benjamin Uzan , Véronique Gelsi-Boyer , Zakia Aid , Cécile Thirant , Ute Moll , Samantha Tauchmann , Amina Kurtovic-Kozaric , Jaroslaw Maciejewski , Christine Dierks , Orietta Spinelli , Silvia Salmoiraghi , Thomas Pabst , Kazuya Shimoda , Virginie Deleuze , Hélène Lapillonne , Connor Sweeney , Véronique De Mas , Betty Leite , Zahra Kadri , Sébastien Malinge , Stéphane de Botton , Jean-Baptiste Micol , Benjamin Kile , Catherine L Carmichael , Ilaria Iacobucci , Charles G Mullighan , Martin Carroll , Peter Valent , Olivier A Bernard , Eric Delabesse , Paresh Vyas , Daniel Birnbaum , Eduardo Anguita , Loïc Garçon , Eric Soler , Juerg Schwaller , Thomas Mercher

Hypoxia favors chemoresistance in T-ALL through an HIF1α-mediated mTORC1 inhibition loop.

Blood advances

Avec: Lucine Fahy , Julien Calvo , Sara Chabi , Laurent Renou , Charly Le Maout , Sandrine Poglio , Thierry Leblanc , Arnaud Petit , André Baruchel , Paola Ballerini , Irina Naguibneva , Rima Haddad , Marie-Laure Arcangeli , Frederic Mazurier , Francoise Pflumio , Benjamin Uzan

T-cell acute lymphoblastic leukemia progression is supported by inflammatory molecules including hepatocyte growth factor.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Charly Le Maout , Lucine Fahy , Laurent Renou , Caroline Devanand , Charlotte Duwat , Vilma Barroca , Morgane Le Gall , Paola Ballerini , Arnaud Petit , Julien Calvo , Benjamin Uzan , Françoise Pflumio , Vanessa Petit

Hypoxia Regulates Lymphoid Development of Human Hematopoietic Progenitors.

Cell reports

Avec: Sara Chabi , Benjamin Uzan , Irina Naguibneva , Julien Rucci , Lucine Fahy , Julien Calvo , Marie-Laure Arcangeli , Frédéric Mazurier , Françoise Pflumio , Rima Haddad

Lithium treatment mitigates the diabetogenic effects of chronic cortico-therapy.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Etienne Delangre , Gaëlle Pommier , Stefania Tolu , Benjamin Uzan , Danielle Bailbé , Jamileh Movassat

T-cell acute lymphoblastic leukemia displays autocrine production of Interleukin-7.

Oncogene

Avec: Anne Buffière , Benjamin Uzan , Romain Aucagne , François Hermetet , Manon Mas , Sandra Nassurdine , Aziza Aznague , Virginie Carmignac , Benjamin Tournier , Olivier Bouchot , Paola Ballerini , João T Barata , Jean-Noël Bastie , Laurent Delva , Françoise Pflumio , Ronan Quéré

Fratricide-resistant CD1a-specific CAR T cells for the treatment of cortical T-cell acute lymphoblastic leukemia.

Blood

Avec: Diego Sánchez-Martínez , Matteo L Baroni , Francisco Gutierrez-Agüera , Heleia Roca-Ho , Oscar Blanch-Lombarte , Sara González-García , Montserrat Torrebadell , Jordi Junca , Manuel Ramírez-Orellana , Talía Velasco-Hernández , Clara Bueno , José Luís Fuster , Julia G Prado , Julien Calvo , Benjamin Uzan , Jan Cools , Mireia Camos , Françoise Pflumio , María Luisa Toribio , Pablo Menéndez

Ultra-high-dose-rate FLASH and Conventional-Dose-Rate Irradiation Differentially Affect Human Acute Lymphoblastic Leukemia and Normal Hematopoiesis.

International journal of radiation oncology, biology, physics

Avec: Sara Chabi , Thi Hong Van To , Ron Leavitt , Sandrine Poglio , Patrik Gonçalves Jorge , Maud Jaccard , Kristoffer Petersson , Benoit Petit , Paul-Henri Roméo , Françoise Pflumio , Marie-Catherine Vozenin , Benjamin Uzan

Downregulation of Glutamine Synthetase, not glutaminolysis, is responsible for glutamine addiction in Notch1-driven acute lymphoblastic leukemia.

Molecular oncology

Avec: Tra Ly Nguyen , Marie-Julie Nokin , Silvia Terés , Mercedes Tomé , Clément Bodineau , Oriane Galmar , Jean-Max Pasquet , Benoit Rousseau , Sebastian van Liempd , Juan Manuel Falcon-Perez , Elodie Richard , Elodie Muzotte , Hamid-Reza Rezvani , Muriel Priault , Marion Bouchecareilh , Isabelle Redonnet-Vernhet , Julien Calvo , Benjamin Uzan , Françoise Pflumio , Patricia Fuentes , Maria L Toribio , Abdel-Majid Khatib , Pierre Soubeyran , Piedad Del Socorro Murdoch , Raúl V Durán

Réseau de co-auteurs

Françoise Pflumio 6 collaborations

Julien Calvo 5 collaborations

Lucine Fahy 3 collaborations

Sara Chabi 3 collaborations

Paola Ballerini 3 collaborations

Laurent Renou 2 collaborations

Charly Le Maout 2 collaborations

Sandrine Poglio 2 collaborations

Arnaud Petit 2 collaborations

Irina Naguibneva 2 collaborations

Rima Haddad 2 collaborations

Marie-Laure Arcangeli 2 collaborations

Alexandre Fagnan 1 collaboration

Frederik Otzen Bagger 1 collaboration

Maria-Riera Piqué-Borràs 1 collaboration

Cathy Ignacimouttou 1 collaboration

Alexis Caulier 1 collaboration

Cécile K Lopez 1 collaboration

Elie Robert 1 collaboration

Véronique Gelsi-Boyer 1 collaboration

Zakia Aid 1 collaboration

Cécile Thirant 1 collaboration

Ute Moll 1 collaboration

Samantha Tauchmann 1 collaboration

Amina Kurtovic-Kozaric 1 collaboration

Jaroslaw Maciejewski 1 collaboration

Christine Dierks 1 collaboration

Orietta Spinelli 1 collaboration

Silvia Salmoiraghi 1 collaboration

Thomas Pabst 1 collaboration

Kazuya Shimoda 1 collaboration

Virginie Deleuze 1 collaboration

Hélène Lapillonne 1 collaboration

Connor Sweeney 1 collaboration

Véronique De Mas 1 collaboration

Betty Leite 1 collaboration

Zahra Kadri 1 collaboration

Sébastien Malinge 1 collaboration

Stéphane de Botton 1 collaboration

Jean-Baptiste Micol 1 collaboration

Benjamin Kile 1 collaboration

Catherine L Carmichael 1 collaboration

Ilaria Iacobucci 1 collaboration

Charles G Mullighan 1 collaboration

Martin Carroll 1 collaboration

Peter Valent 1 collaboration

Olivier A Bernard 1 collaboration

Eric Delabesse 1 collaboration

Paresh Vyas 1 collaboration

Daniel Birnbaum 1 collaboration

Eduardo Anguita 1 collaboration

Loïc Garçon 1 collaboration

Eric Soler 1 collaboration

Juerg Schwaller 1 collaboration

Thomas Mercher 1 collaboration

Thierry Leblanc 1 collaboration

André Baruchel 1 collaboration

Frederic Mazurier 1 collaboration

Francoise Pflumio 1 collaboration

Caroline Devanand 1 collaboration

Charlotte Duwat 1 collaboration

Vilma Barroca 1 collaboration

Morgane Le Gall 1 collaboration

Vanessa Petit 1 collaboration

Julien Rucci 1 collaboration

Frédéric Mazurier 1 collaboration

Etienne Delangre 1 collaboration

Gaëlle Pommier 1 collaboration

Stefania Tolu 1 collaboration

Danielle Bailbé 1 collaboration

Jamileh Movassat 1 collaboration

Anne Buffière 1 collaboration

Romain Aucagne 1 collaboration

François Hermetet 1 collaboration

Manon Mas 1 collaboration

Sandra Nassurdine 1 collaboration

Aziza Aznague 1 collaboration

Virginie Carmignac 1 collaboration

Benjamin Tournier 1 collaboration

Olivier Bouchot 1 collaboration

João T Barata 1 collaboration

Jean-Noël Bastie 1 collaboration

Laurent Delva 1 collaboration

Ronan Quéré 1 collaboration

Diego Sánchez-Martínez 1 collaboration

Matteo L Baroni 1 collaboration

Francisco Gutierrez-Agüera 1 collaboration

Heleia Roca-Ho 1 collaboration

Oscar Blanch-Lombarte 1 collaboration

Sara González-García 1 collaboration

Montserrat Torrebadell 1 collaboration

Jordi Junca 1 collaboration

Manuel Ramírez-Orellana 1 collaboration

Talía Velasco-Hernández 1 collaboration

Clara Bueno 1 collaboration

José Luís Fuster 1 collaboration

Julia G Prado 1 collaboration

Jan Cools 1 collaboration

Mireia Camos 1 collaboration

María Luisa Toribio 1 collaboration

Pablo Menéndez 1 collaboration

Thi Hong Van To 1 collaboration

Ron Leavitt 1 collaboration

Patrik Gonçalves Jorge 1 collaboration

Maud Jaccard 1 collaboration

Kristoffer Petersson 1 collaboration

Benoit Petit 1 collaboration

Paul-Henri Roméo 1 collaboration

Marie-Catherine Vozenin 1 collaboration

Tra Ly Nguyen 1 collaboration

Marie-Julie Nokin 1 collaboration

Silvia Terés 1 collaboration

Mercedes Tomé 1 collaboration

Clément Bodineau 1 collaboration

Oriane Galmar 1 collaboration

Jean-Max Pasquet 1 collaboration

Benoit Rousseau 1 collaboration

Sebastian van Liempd 1 collaboration

Juan Manuel Falcon-Perez 1 collaboration

Elodie Richard 1 collaboration

Elodie Muzotte 1 collaboration

Hamid-Reza Rezvani 1 collaboration

Muriel Priault 1 collaboration

Marion Bouchecareilh 1 collaboration

Isabelle Redonnet-Vernhet 1 collaboration

Patricia Fuentes 1 collaboration

Maria L Toribio 1 collaboration

Abdel-Majid Khatib 1 collaboration

Pierre Soubeyran 1 collaboration

Piedad Del Socorro Murdoch 1 collaboration

Raúl V Durán 1 collaboration