Benoit Gigant

Affiliations

Université Paris-Saclay, CEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), 91198, Gif-sur-Yvette, France.

Publications (12)

Insight into microtubule nucleation from tubulin-capping proteins.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Valérie Campanacci , Agathe Urvoas , Soraya Cantos-Fernandes , Magali Aumont-Nicaise , Ana-Andreea Arteni , Christophe Velours , Marie Valerio-Lepiniec , Birgit Dreier , Andreas Plückthun , Antoine Pilon , Christian Poüs , Philippe Minard , Benoît Gigant

Selection and Characterization of Artificial Proteins Targeting the Tubulin α Subunit.

Structure (London, England : 1993)

Avec: Valérie Campanacci , Agathe Urvoas , Tanja Consolati , Soraya Cantos-Fernandes , Magali Aumont-Nicaise , Marie Valerio-Lepiniec , Thomas Surrey , Philippe Minard , Benoît Gigant

The Mechanism of Tubulin Assembly into Microtubules: Insights from Structural Studies.

iScience

Avec: Marcel Knossow , Valérie Campanacci , Liza Ammar Khodja , Benoît Gigant

GTP-dependent formation of straight tubulin oligomers leads to microtubule nucleation.

The Journal of cell biology

Avec: Rie Ayukawa , Seigo Iwata , Hiroshi Imai , Shinji Kamimura , Masahito Hayashi , Kien Xuan Ngo , Itsushi Minoura , Seiichi Uchimura , Tsukasa Makino , Mikako Shirouzu , Hideki Shigematsu , Ken Sekimoto , Benoît Gigant , Etsuko Muto

Structural snapshots of the kinesin-2 OSM-3 along its nucleotide cycle: implications for the ATP hydrolysis mechanism.

FEBS open bio

Avec: Paloma F Varela , Mélanie Chenon , Christophe Velours , Kristen J Verhey , Julie Ménétrey , Benoît Gigant

Elucidating Tau function and dysfunction in the era of cryo-EM.

The Journal of biological chemistry

Avec: Guy Lippens , Benoît Gigant

Discovery of dihydrofuranoallocolchicinoids - Highly potent antimitotic agents with low acute toxicity.

European journal of medicinal chemistry

Avec: Ekaterina S Shchegravina , Elena V Svirshchevskaya , Sebastien Combes , Diane Allegro , Pascale Barbier , Benoit Gigant , Paloma F Varela , Andrei E Gavryushin , Daria A Kobanova , Andrey E Shchekotikhin , Alexey Yu Fedorov

1,1-Diheterocyclic Ethylenes Derived from Quinaldine and Carbazole as New Tubulin-Polymerization Inhibitors: Synthesis, Metabolism, and Biological Evaluation.

Journal of medicinal chemistry

Avec: Timothée Naret , Ilhem Khelifi , Olivier Provot , Jérôme Bignon , Hélène Levaique , Joelle Dubois , Martin Souce , Athena Kasselouri , Alain Deroussent , Angélo Paci , Paloma F Varela , Benoît Gigant , Mouad Alami , Abdallah Hamze

B-nor-methylene Colchicinoid PT-100 Selectively Induces Apoptosis in Multidrug-Resistant Human Cancer Cells via an Intrinsic Pathway in a Caspase-Independent Manner.

ACS omega

Avec: Andreas Stein , Persefoni Hilken Née Thomopoulou , Corazon Frias , Sina M Hopff , Paloma Varela , Nicola Wilke , Arul Mariappan , Jörg-Martin Neudörfl , Alexey Yu Fedorov , Jay Gopalakrishnan , Benoît Gigant , Aram Prokop , Hans-Günther Schmalz

Structural convergence for tubulin binding of CPAP and vinca domain microtubule inhibitors.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Valérie Campanacci , Agathe Urvoas , Liza Ammar Khodja , Magali Aumont-Nicaise , Magali Noiray , Sylvie Lachkar , Patrick A Curmi , Philippe Minard , Benoît Gigant

Engineering of brick and staple components for ordered assembly of synthetic repeat proteins.

Journal of structural biology

Avec: Jessalyn Miller , Agathe Urvoas , Benoit Gigant , Malika Ouldali , Ana Arteni , Agnes Mesneau , Marie Valerio-Lepiniec , Franck Artzner , Erik Dujardin , Philippe Minard

The C-terminus of stathmin-like proteins governs the stability of their complexes with tubulin.

Biochemical and biophysical research communications

Avec: Valérie Campanacci , Benoît Gigant

Réseau de co-auteurs

Benoît Gigant 10 collaborations

Valérie Campanacci 5 collaborations

Agathe Urvoas 4 collaborations

Philippe Minard 4 collaborations

Magali Aumont-Nicaise 3 collaborations

Marie Valerio-Lepiniec 3 collaborations

Paloma F Varela 3 collaborations

Soraya Cantos-Fernandes 2 collaborations

Christophe Velours 2 collaborations

Liza Ammar Khodja 2 collaborations

Alexey Yu Fedorov 2 collaborations

Ana-Andreea Arteni 1 collaboration

Birgit Dreier 1 collaboration

Andreas Plückthun 1 collaboration

Antoine Pilon 1 collaboration

Christian Poüs 1 collaboration

Tanja Consolati 1 collaboration

Thomas Surrey 1 collaboration

Marcel Knossow 1 collaboration

Rie Ayukawa 1 collaboration

Seigo Iwata 1 collaboration

Hiroshi Imai 1 collaboration

Shinji Kamimura 1 collaboration

Masahito Hayashi 1 collaboration

Kien Xuan Ngo 1 collaboration

Itsushi Minoura 1 collaboration

Seiichi Uchimura 1 collaboration

Tsukasa Makino 1 collaboration

Mikako Shirouzu 1 collaboration

Hideki Shigematsu 1 collaboration

Ken Sekimoto 1 collaboration

Etsuko Muto 1 collaboration

Mélanie Chenon 1 collaboration

Kristen J Verhey 1 collaboration

Julie Ménétrey 1 collaboration

Guy Lippens 1 collaboration

Ekaterina S Shchegravina 1 collaboration

Elena V Svirshchevskaya 1 collaboration

Sebastien Combes 1 collaboration

Diane Allegro 1 collaboration

Pascale Barbier 1 collaboration

Andrei E Gavryushin 1 collaboration

Daria A Kobanova 1 collaboration

Andrey E Shchekotikhin 1 collaboration

Timothée Naret 1 collaboration

Ilhem Khelifi 1 collaboration

Olivier Provot 1 collaboration

Jérôme Bignon 1 collaboration

Hélène Levaique 1 collaboration

Joelle Dubois 1 collaboration

Martin Souce 1 collaboration

Athena Kasselouri 1 collaboration

Alain Deroussent 1 collaboration

Angélo Paci 1 collaboration

Mouad Alami 1 collaboration

Abdallah Hamze 1 collaboration

Andreas Stein 1 collaboration

Persefoni Hilken Née Thomopoulou 1 collaboration

Corazon Frias 1 collaboration

Sina M Hopff 1 collaboration

Paloma Varela 1 collaboration

Nicola Wilke 1 collaboration

Arul Mariappan 1 collaboration

Jörg-Martin Neudörfl 1 collaboration

Jay Gopalakrishnan 1 collaboration

Aram Prokop 1 collaboration

Hans-Günther Schmalz 1 collaboration

Magali Noiray 1 collaboration

Sylvie Lachkar 1 collaboration

Patrick A Curmi 1 collaboration

Jessalyn Miller 1 collaboration

Malika Ouldali 1 collaboration

Ana Arteni 1 collaboration

Agnes Mesneau 1 collaboration

Franck Artzner 1 collaboration

Erik Dujardin 1 collaboration