C M Hedrich

Affiliations

Department of Women's & Children's Health, Institute of Life Course and Medical Sciences, University of Liverpool, Liverpool, UK. christian.hedrich@liverpool.ac.uk.
Department of Paediatric Rheumatology, Alder Hey Children's NHS Foundation Trust Hospital, Liverpool, UK. christian.hedrich@liverpool.ac.uk.
Institute in the Park, Alder Hey Children's NHS Foundation Trust Hospital, East Prescot Road, Liverpool, L14 5AB, UK. christian.hedrich@liverpool.ac.uk.

ORCID: 0000-0002-1295-6179

Publications (32)

COVID-19: Immunology and treatment options.

Clinical immunology (Orlando, Fla.)

Avec: Susanna Felsenstein , Jenny A Herbert , Paul S McNamara , Christian M Hedrich

Biosimilars in pediatric rheumatology and their introduction into routine care.

Clinical immunology (Orlando, Fla.)

Avec: Octavio Aragon Cuevas , Christian M Hedrich

COVID-19 - Considerations for the paediatric rheumatologist.

Clinical immunology (Orlando, Fla.)

Avec: Christian M Hedrich

The Molecular Pathophysiology of Psoriatic Arthritis-The Complex Interplay Between Genetic Predisposition, Epigenetics Factors, and the Microbiome.

Frontiers in molecular biosciences

Avec: Ana L Carvalho , Christian M Hedrich

Chronic nonbacterial osteomyelitis (CNO) and chronic recurrent multifocal osteomyelitis (CRMO).

Journal of translational autoimmunity

Avec: Dan Yongdong Zhao , Liza McCann , Gabriele Hahn , Christian M Hedrich

Systemic Lupus Erythematosus in Children and Young People.

Current rheumatology reports

Avec: A Charras , E Smith , C M Hedrich

Neuropsychiatric involvement in juvenile-onset systemic lupus erythematosus: Data from the UK Juvenile-onset systemic lupus erythematosus cohort study.

Lupus

Avec: Teresa Giani , Eve Md Smith , Eslam Al-Abadi , Kate Armon , Kathryn Bailey , Coziana Ciurtin , Joyce Davidson , Janet Gardner-Medwin , Kirsty Haslam , Dan P Hawley , Alice Leahy , Valentina Leone , Flora McErlane , Devesh Mewar , Gita Modgil , Robert Moots , Clarissa Pilkington , Francesca Pregnolato , Athimalaipet V Ramanan , Satyapal Rangaraj , Phil Riley , Arani Sridhar , Nick Wilkinson , Rolando Cimaz , Michael W Beresford , Christian M Hedrich , Auteur inconnu

TNF-inhibitors or bisphosphonates in chronic nonbacterial osteomyelitis? - Results of an international retrospective multicenter study.

Clinical immunology (Orlando, Fla.)

Avec: A Schnabel , M Nashawi , C Anderson , S Felsenstein , M Lamoudi , J Poole-Cowley , E Lindell , B Oates , P Fowlie , J Walsh , T Ellis , G Hahn , A Goldspink , N Martin , K Mahmood , T Hospach , McCann Lj , C M Hedrich

Priorities in Chronic nonbacterial osteomyelitis (CNO) - results from an international survey and roundtable discussions.

Pediatric rheumatology online journal

Avec: M Mohanna , E Roberts , L Whitty , J F Gritzfeld , C E Pain , H J Girschick , J Preston , M Hadjittofi , C Anderson , P J Ferguson , A Theos , C M Hedrich

Age-differential CD13 and interferon expression in airway epithelia affect SARS-CoV-2 infection - Effects of vitamin D.

Mucosal immunology

Avec: Francesca Sposito , Shaun H Pennington , Christopher A W David , Jack Duggan , Sarah Northey , Giancarlo A Biagini , Neill J Liptrott , Amandine Charras , Paul S McNamara , Christian M Hedrich

[COVID-19: treatment strategies of German-speaking pediatric rheumatologists : Results of an online survey].

Zeitschrift fur Rheumatologie

Avec: A Janda , C Schuetz , M Heeg , K Minden , C M Hedrich , T Kallinich , C Hinze , A Schulz , F Speth

High-dose intravenous methylprednisolone in juvenile non-infectious uveitis: A retrospective analysis.

Clinical immunology (Orlando, Fla.)

Avec: Anja Schnabel , Elisabeth Unger , Normi Brück , Reinhard Berner , Ursula Range , Annette Holl-Wieden , Henner Morbach , Anna Leszczynska , Viktoria Bau , Christian M Hedrich

Defining consensus opinion to develop randomised controlled trials in rare diseases using Bayesian design: An example of a proposed trial of adalimumab versus pamidronate for children with CNO/CRMO.

PloS one

Avec: A V Ramanan , L V Hampson , H Lythgoe , A P Jones , B Hardwick , H Hind , B Jacobs , D Vasileiou , I Wadsworth , N Ambrose , J Davidson , P J Ferguson , T Herlin , A Kavirayani , O G Killeen , S Compeyrot-Lacassagne , R M Laxer , M Roderick , J F Swart , C M Hedrich , M W Beresford

Outcomes following mycophenolate mofetil versus cyclophosphamide induction treatment for proliferative juvenile-onset lupus nephritis.

Lupus

Avec: Emd Smith , E Al-Abadi , K Armon , K Bailey , C Ciurtin , J Davidson , J Gardner-Medwin , K Haslam , D Hawley , A Leahy , V Leone , F McErlane , D Mewar , G Modgil , R Moots , C Pilkington , A Ramanan , S Rangaraj , P Riley , A Sridhar , N Wilkinson , M W Beresford , C M Hedrich

CASP1 variants influence subcellular caspase-1 localization, pyroptosome formation, pro-inflammatory cell death and macrophage deformability.

Clinical immunology (Orlando, Fla.)

Avec: Franz Kapplusch , Felix Schulze , Sabrina Rabe-Matschewsky , Susanne Russ , Maik Herbig , Michael Christian Heymann , Katharina Schoepf , Robert Stein , Ursula Range , Angela Rösen-Wolff , Stefan Winkler , Christian Michael Hedrich , Jochen Guck , Sigrun Ruth Hofmann

Diagnosis and Treatment of Angiography Positive Medium to Large Vessel Childhood Primary Angiitis of Central Nervous System (p-cPACNS): An International Survey.

Frontiers in pediatrics

Avec: Angela S Quan , Jürgen Brunner , Benjamin Rose , Martin Smitka , Gabriele Hahn , Clare E Pain , Renate Häfner , Fabian Speth , Lucia Gerstl , Christian M Hedrich

New Insights into Adult and Paediatric Chronic Non-bacterial Osteomyelitis CNO.

Current rheumatology reports

Avec: Christian M Hedrich , Henner Morbach , Christiane Reiser , Hermann J Girschick

A panel of urinary proteins predicts active lupus nephritis and response to rituximab treatment.

Rheumatology (Oxford, England)

Avec: Jennifer C Davies , Emil Carlsson , Angela Midgley , Eve M D Smith , Ian N Bruce , Michael W Beresford , Christian M Hedrich , Auteur inconnu

Systemic lupus erythematosus - Are children miniature adults?

Clinical immunology (Orlando, Fla.)

Avec: Tobias Alexander , Christian M Hedrich

Attainment of low disease activity and remission targets reduces the risk of severe flare and new damage in childhood lupus.

Rheumatology (Oxford, England)

Avec: Eve M D Smith , Kukatharmini Tharmaratnam , Eslam Al-Abadi , Kate Armon , Kathryn Bailey , Mary Brennan , Coziana Ciurtin , Janet Gardner-Medwin , Kirsty E Haslam , Daniel Hawley , Alice Leahy , Valentina Leone , Gulshan Malik , Zoe McLaren , Clarissa Pilkington , Athimalaipet V Ramanan , Satyapal Rangaraj , Annie Ratcliffe , Philip Riley , Ethan Sen , Arani Sridhar , Nick Wilkinson , Christian M Hedrich , Andrea Jorgensen , Michael W Beresford

Longitudinal analysis of urinary proteins in lupus nephritis - A pilot study.

Clinical immunology (Orlando, Fla.)

Avec: Emil Carlsson , Alexandra Quist , Jennifer C Davies , Angela Midgley , Eve M D Smith , Ian N Bruce , Michael W Beresford , Christian M Hedrich , Auteur inconnu

RIP2-deficiency induces inflammation in response to SV40 Large T induced genotoxic stress through altered ROS homeostasis.

Clinical immunology (Orlando, Fla.)

Avec: Franz Kapplusch , Felix Schulze , Sören Reinke , Susanne Russ , Mary Linge , Franziska Kulling , Florian Kriechling , Katrin Höhne , Stefan Winkler , Hella Hartmann , Angela Rösen-Wolff , Konstantinos Anastassiadis , Christian M Hedrich , Sigrun R Hofmann

Towards development of treat to target (T2T) in childhood-onset systemic lupus erythematosus: PReS-endorsed overarching principles and points-to-consider from an international task force.

Annals of the rheumatic diseases

Avec: Eve Mary Dorothy Smith , Amita Aggarwal , Jenny Ainsworth , Eslam Al-Abadi , Tadej Avcin , Lynette Bortey , Jon Burnham , Coziana Ciurtin , Christian M Hedrich , Sylvia Kamphuis , Deborah M Levy , Laura B Lewandowski , Naomi Maxwell , Eric F Morand , Seza Ozen , Clare E Pain , Angelo Ravelli , Claudia Saad Magalhaes , Clarissa A Pilkington , Dieneke Schonenberg-Meinema , Christiaan Scott , Kjell Tullus , Michael William Beresford , Auteur inconnu

Demographic, clinical and laboratory differences between paediatric acute COVID-19 and PIMS-TS-results from a single centre study in the UK.

Frontiers in pediatrics

Avec: Prince Jiju , Michail Matalliotakis , Steven Lane , Waison Wong , Christian M Hedrich , Clare E Pain

An improved understanding of paediatric chronic nonbacterial osteomyelitis (CNO) pathophysiology informs current and future treatment.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research

Avec: Eve Roberts , Amandine Charras , Gabriele Hahn , Christian M Hedrich

Development of CARRA/PReS-endorsed consensus Core and Expanded Datasets in childhood-onset systemic lupus erythematosus for international registry-based research.

Annals of the rheumatic diseases

Avec: Rebecca E Sadun , Jennifer C Cooper , Alexandre Belot , Tadej Avcin , Amita Aggarwal , Jenny Ainsworth , Alisha Akinsete , Stacy P Ardoin , Michael W Beresford , Lynette Bortey , Hermine I Brunner , Joyce C Chang , Coziana Ciurtin , Ashley Daftary , Barbara Eberhard , Candace H Feldman , Christian M Hedrich , Aimee O Hersh , Linda T Hiraki , David A Isenberg , Sylvia Kamphuis , Andrea M Knight , Lou Lambert , Deborah M Levy , Stephen D Marks , Naomi Maxwell , Angela Migowa , Katharine Moore , Seza Ozen , Rosalind Ramsey-Goldman , Angelo Ravelli , Bryce B Reeve , Tamar B Rubinstein , Claudia Saad-Magalhaes , Sujata Sawhney , Laura E Schanberg , Emily von Scheven , Christiaan Scott , Mary Beth Son , Gladys Tony , Elissa R Weitzman , Scott E Wenderfer , Alisha Woodside , Laura B Lewandowski , Eve Md Smith , Auteur inconnu

Differential analysis of serum and urine S100 proteins in juvenile-onset systemic lupus erythematosus (jSLE).

Clinical immunology (Orlando, Fla.)

Avec: S J Donohue , A Midgley , J C Davies , R D Wright , I Bruce , M W Beresford , C M Hedrich , Auteur inconnu , Auteur inconnu

The role of epigenetics in paediatric rheumatic disease.

Current opinion in rheumatology

Avec: Amandine Charras , Christian M Hedrich

The Role of Epigenetics in Autoimmune/Inflammatory Disease.

Frontiers in immunology

Avec: Anna Elisa Andrea Surace , Christian M Hedrich

Juvenile-onset systemic lupus erythematosus: Update on clinical presentation, pathophysiology and treatment options.

Clinical immunology (Orlando, Fla.)

Avec: Eve Mary Dorothy Smith , Hanna Lythgoe , Angela Midgley , Michael William Beresford , Christian Michael Hedrich

Diagnosis and Treatment of Small Vessel Childhood Primary Angiitis of the Central Nervous System (sv-cPACNS): An International Survey.

Frontiers in pediatrics

Avec: Paul Keenan , Jürgen Brunner , Angela S Quan , Martin Smitka , Gabriele Hahn , Clare E Pain , Renate Häfner , Fabian Speth , Lucia Gerstl , Christian M Hedrich

Panel sequencing links rare, likely damaging gene variants with distinct clinical phenotypes and outcomes in juvenile-onset SLE.

Rheumatology (Oxford, England)

Avec: Amandine Charras , Sam Haldenby , Eve M D Smith , Naomi Egbivwie , Lisa Olohan , John G Kenny , Klaus Schwarz , Carla Roberts , Eslam Al-Abadi , Kate Armon , Kathryn Bailey , Coziana Ciurtin , Janet Gardner-Medwin , Kirsty Haslam , Daniel P Hawley , Alice Leahy , Valentina Leone , Flora McErlane , Gita Modgil , Clarissa Pilkington , Athimalaipet V Ramanan , Satyapal Rangaraj , Phil Riley , Arani Sridhar , Michael W Beresford , Christian M Hedrich

Réseau de co-auteurs

Christian M Hedrich 23 collaborations

None None 7 collaborations

Michael W Beresford 6 collaborations

Coziana Ciurtin 5 collaborations

Gabriele Hahn 4 collaborations

Eslam Al-Abadi 4 collaborations

Amandine Charras 4 collaborations

Clare E Pain 4 collaborations

Eve M D Smith 4 collaborations

Kate Armon 3 collaborations

Kathryn Bailey 3 collaborations

Janet Gardner-Medwin 3 collaborations

Alice Leahy 3 collaborations

Valentina Leone 3 collaborations

Clarissa Pilkington 3 collaborations

Athimalaipet V Ramanan 3 collaborations

Satyapal Rangaraj 3 collaborations

Arani Sridhar 3 collaborations

M W Beresford 3 collaborations

Angela Midgley 3 collaborations

Paul S McNamara 2 collaborations

Eve Md Smith 2 collaborations

Kirsty Haslam 2 collaborations

Flora McErlane 2 collaborations

Gita Modgil 2 collaborations

Phil Riley 2 collaborations

Nick Wilkinson 2 collaborations

C Anderson 2 collaborations

P J Ferguson 2 collaborations

Ursula Range 2 collaborations

Henner Morbach 2 collaborations

J Davidson 2 collaborations

Franz Kapplusch 2 collaborations

Felix Schulze 2 collaborations

Susanne Russ 2 collaborations

Angela Rösen-Wolff 2 collaborations

Stefan Winkler 2 collaborations

Christian Michael Hedrich 2 collaborations

Angela S Quan 2 collaborations

Jürgen Brunner 2 collaborations

Martin Smitka 2 collaborations

Renate Häfner 2 collaborations

Fabian Speth 2 collaborations

Lucia Gerstl 2 collaborations

Jennifer C Davies 2 collaborations

Emil Carlsson 2 collaborations

Ian N Bruce 2 collaborations

Eve Mary Dorothy Smith 2 collaborations

Amita Aggarwal 2 collaborations

Jenny Ainsworth 2 collaborations

Tadej Avcin 2 collaborations

Lynette Bortey 2 collaborations

Sylvia Kamphuis 2 collaborations

Deborah M Levy 2 collaborations

Laura B Lewandowski 2 collaborations

Naomi Maxwell 2 collaborations

Seza Ozen 2 collaborations

Angelo Ravelli 2 collaborations

Christiaan Scott 2 collaborations

Michael William Beresford 2 collaborations

Susanna Felsenstein 1 collaboration

Jenny A Herbert 1 collaboration

Octavio Aragon Cuevas 1 collaboration

Ana L Carvalho 1 collaboration

Dan Yongdong Zhao 1 collaboration

Liza McCann 1 collaboration

A Charras 1 collaboration

E Smith 1 collaboration

Teresa Giani 1 collaboration

Joyce Davidson 1 collaboration

Dan P Hawley 1 collaboration

Devesh Mewar 1 collaboration

Robert Moots 1 collaboration

Francesca Pregnolato 1 collaboration

Rolando Cimaz 1 collaboration

A Schnabel 1 collaboration

M Nashawi 1 collaboration

S Felsenstein 1 collaboration

M Lamoudi 1 collaboration

J Poole-Cowley 1 collaboration

E Lindell 1 collaboration

B Oates 1 collaboration

P Fowlie 1 collaboration

J Walsh 1 collaboration

T Ellis 1 collaboration

G Hahn 1 collaboration

A Goldspink 1 collaboration

N Martin 1 collaboration

K Mahmood 1 collaboration

T Hospach 1 collaboration

McCann Lj 1 collaboration

M Mohanna 1 collaboration

E Roberts 1 collaboration

L Whitty 1 collaboration

J F Gritzfeld 1 collaboration

C E Pain 1 collaboration

H J Girschick 1 collaboration

J Preston 1 collaboration

M Hadjittofi 1 collaboration

A Theos 1 collaboration

Francesca Sposito 1 collaboration

Shaun H Pennington 1 collaboration

Christopher A W David 1 collaboration

Jack Duggan 1 collaboration

Sarah Northey 1 collaboration

Giancarlo A Biagini 1 collaboration

Neill J Liptrott 1 collaboration

A Janda 1 collaboration

C Schuetz 1 collaboration

M Heeg 1 collaboration

K Minden 1 collaboration

T Kallinich 1 collaboration

C Hinze 1 collaboration

A Schulz 1 collaboration

F Speth 1 collaboration

Anja Schnabel 1 collaboration

Elisabeth Unger 1 collaboration

Normi Brück 1 collaboration

Reinhard Berner 1 collaboration

Annette Holl-Wieden 1 collaboration

Anna Leszczynska 1 collaboration

Viktoria Bau 1 collaboration

A V Ramanan 1 collaboration

L V Hampson 1 collaboration

H Lythgoe 1 collaboration

A P Jones 1 collaboration

B Hardwick 1 collaboration

H Hind 1 collaboration

B Jacobs 1 collaboration

D Vasileiou 1 collaboration

I Wadsworth 1 collaboration

N Ambrose 1 collaboration

T Herlin 1 collaboration

A Kavirayani 1 collaboration

O G Killeen 1 collaboration

S Compeyrot-Lacassagne 1 collaboration

R M Laxer 1 collaboration

M Roderick 1 collaboration

J F Swart 1 collaboration

Emd Smith 1 collaboration

E Al-Abadi 1 collaboration

K Armon 1 collaboration

K Bailey 1 collaboration

C Ciurtin 1 collaboration

J Gardner-Medwin 1 collaboration

K Haslam 1 collaboration

D Hawley 1 collaboration

A Leahy 1 collaboration

V Leone 1 collaboration

F McErlane 1 collaboration

D Mewar 1 collaboration

G Modgil 1 collaboration

R Moots 1 collaboration

C Pilkington 1 collaboration

A Ramanan 1 collaboration

S Rangaraj 1 collaboration

P Riley 1 collaboration

A Sridhar 1 collaboration

N Wilkinson 1 collaboration

Sabrina Rabe-Matschewsky 1 collaboration

Maik Herbig 1 collaboration

Michael Christian Heymann 1 collaboration

Katharina Schoepf 1 collaboration

Robert Stein 1 collaboration

Jochen Guck 1 collaboration

Sigrun Ruth Hofmann 1 collaboration

Benjamin Rose 1 collaboration

Christiane Reiser 1 collaboration

Hermann J Girschick 1 collaboration

Tobias Alexander 1 collaboration

Kukatharmini Tharmaratnam 1 collaboration

Mary Brennan 1 collaboration

Kirsty E Haslam 1 collaboration

Daniel Hawley 1 collaboration

Gulshan Malik 1 collaboration

Zoe McLaren 1 collaboration

Annie Ratcliffe 1 collaboration

Philip Riley 1 collaboration

Ethan Sen 1 collaboration

Andrea Jorgensen 1 collaboration

Alexandra Quist 1 collaboration

Sören Reinke 1 collaboration

Mary Linge 1 collaboration

Franziska Kulling 1 collaboration

Florian Kriechling 1 collaboration

Katrin Höhne 1 collaboration

Hella Hartmann 1 collaboration

Konstantinos Anastassiadis 1 collaboration

Sigrun R Hofmann 1 collaboration

Jon Burnham 1 collaboration

Eric F Morand 1 collaboration

Claudia Saad Magalhaes 1 collaboration

Clarissa A Pilkington 1 collaboration

Dieneke Schonenberg-Meinema 1 collaboration

Kjell Tullus 1 collaboration

Prince Jiju 1 collaboration

Michail Matalliotakis 1 collaboration

Steven Lane 1 collaboration

Waison Wong 1 collaboration

Eve Roberts 1 collaboration

Rebecca E Sadun 1 collaboration

Jennifer C Cooper 1 collaboration

Alexandre Belot 1 collaboration

Alisha Akinsete 1 collaboration

Stacy P Ardoin 1 collaboration

Hermine I Brunner 1 collaboration

Joyce C Chang 1 collaboration

Ashley Daftary 1 collaboration

Barbara Eberhard 1 collaboration

Candace H Feldman 1 collaboration

Aimee O Hersh 1 collaboration

Linda T Hiraki 1 collaboration

David A Isenberg 1 collaboration

Andrea M Knight 1 collaboration

Lou Lambert 1 collaboration

Stephen D Marks 1 collaboration

Angela Migowa 1 collaboration

Katharine Moore 1 collaboration

Rosalind Ramsey-Goldman 1 collaboration

Bryce B Reeve 1 collaboration

Tamar B Rubinstein 1 collaboration

Claudia Saad-Magalhaes 1 collaboration

Sujata Sawhney 1 collaboration

Laura E Schanberg 1 collaboration

Emily von Scheven 1 collaboration

Mary Beth Son 1 collaboration

Gladys Tony 1 collaboration

Elissa R Weitzman 1 collaboration

Scott E Wenderfer 1 collaboration

Alisha Woodside 1 collaboration

S J Donohue 1 collaboration

A Midgley 1 collaboration

J C Davies 1 collaboration

R D Wright 1 collaboration

I Bruce 1 collaboration

Anna Elisa Andrea Surace 1 collaboration

Hanna Lythgoe 1 collaboration

Paul Keenan 1 collaboration

Sam Haldenby 1 collaboration

Naomi Egbivwie 1 collaboration

Lisa Olohan 1 collaboration

John G Kenny 1 collaboration

Klaus Schwarz 1 collaboration

Carla Roberts 1 collaboration

Daniel P Hawley 1 collaboration