Chris A Flask

Affiliations

From the Departments of Radiology (C.J.M., S.F., J.R.P., N.P., M.A.G., D.M., C.A.F., Y.C.), Genetics and Genome Sciences (M.L.D.), Pediatrics (M.L.D., K.M.D., C.A.F.), and Biomedical Engineering (M.A.G., D.M., C.A.F.), Case Western Reserve University, 11100 Euclid Ave, Bowell Building, Room B131, Cleveland, OH 44106; Departments of Radiology (M.M.) and Pediatrics (K.M., K.K.), University Hospitals Cleveland Medical Center, Cleveland, Ohio; and Center for Pediatric Nephrology, Cleveland Clinic Children's Hospital, Cleveland, Ohio (A.P., K.M.D.).

Publications (26)

CPAP-induced airway hyper-reactivity in mice is modulated by hyaluronan synthase-3.

Pediatric research

Avec: Catherine A Mayer , Abhrajit Ganguly , Aubrey Mayer , Christina M Pabelick , Y S Prakash , Vince C Hascall , Ron J Midura , Valbona Cali , Christopher A Flask , Bernadette O Erokwu , Richard J Martin , Peter M MacFarlane

Rapid B

Radiology

Avec: Christina J MacAskill , Michael Markley , Susan Farr , Ashlee Parsons , Jacob R Perino , Kimberly McBennett , Katherine Kutney , Mitchell L Drumm , Nicole Pritts , Mark A Griswold , Dan Ma , Katherine M Dell , Chris A Flask , Yong Chen

Transport pathways and kinetics of cerebrospinal fluid tracers in mouse brain observed by dynamic contrast-enhanced MRI.

Scientific reports

Avec: Yuran Zhu , Guanhua Wang , Chaitanya Kolluru , Yuning Gu , Huiyun Gao , Jing Zhang , Yunmei Wang , David L Wilson , Xiaofeng Zhu , Chris A Flask , Xin Yu

A minimally invasive bronchoscopic approach for direct delivery to murine airways and application to models of pulmonary infection.

Laboratory animals

Avec: Karen Schelde , Julie Rosenjack , Claire Sonneborn , Anjum Jafri , Michael Kavran , Sarah Brumbaugh , Arne Rietsch , Rebecca J Darrah , Craig A Hodges , Christopher A Flask , Thomas J Kelley , Mitchell L Drumm

Multi-parametric MRI of kidney disease progression for autosomal recessive polycystic kidney disease: mouse model and initial patient results.

Pediatric research

Avec: Christina J MacAskill , Bernadette O Erokwu , Michael Markley , Ashlee Parsons , Susan Farr , Yifan Zhang , Uyen Tran , Yong Chen , Christian E Anderson , Suraj Serai , Erum A Hartung , Oliver Wessely , Dan Ma , Katherine M Dell , Chris A Flask

β-Hydroxybutyrate is reduced in humans with obesity-related NAFLD and displays a dose-dependent effect on skeletal muscle mitochondrial respiration in vitro.

American journal of physiology. Endocrinology and metabolism

Avec: Jacob T Mey , Melissa L Erickson , Christopher L Axelrod , William T King , Chris A Flask , Arthur J McCullough , John P Kirwan

Lung T1 mapping magnetic resonance imaging in the assessment of pulmonary disease in children with cystic fibrosis: a pilot study.

Pediatric radiology

Avec: Fatima Neemuchwala , Maryam Ghadimi Mahani , Yuxi Pang , Eunjee Lee , Timothy D Johnson , Craig J Galbán , Aleksa B Fortuna , Ramon Sanchez-Jacob , Chris A Flask , Samya Z Nasr

3D MR fingerprinting for dynamic contrast-enhanced imaging of whole mouse brain.

Magnetic resonance in medicine

Avec: Yuran Zhu , Guanhua Wang , Yuning Gu , Walter Zhao , Jiahao Lu , Junqing Zhu , Christina J MacAskill , Andrew Dupuis , Mark A Griswold , Dan Ma , Chris A Flask , Xin Yu

Increased cerebral vascularization and decreased water exchange across the blood-brain barrier in aquaporin-4 knockout mice.

PloS one

Avec: Yifan Zhang , Kui Xu , Yuchi Liu , Bernadette O Erokwu , Pan Zhao , Chris A Flask , Ciro Ramos-Estebanez , George W Farr , Joseph C LaManna , Walter F Boron , Xin Yu

PTPmu-targeted nanoparticles label invasive pediatric and adult glioblastoma.

Nanomedicine : nanotechnology, biology, and medicine

Avec: Gil Covarrubias , Mette L Johansen , Jason Vincent , Bernadette O Erokwu , Sonya E L Craig , Abdelrahman Rahmy , Anthony Cha , Morgan Lorkowski , Christina MacAskill , Bryan Scott , Madhusudhana Gargesha , Debashish Roy , Chris A Flask , Efstathios Karathanasis , Susann M Brady-Kalnay

Specimen specific imaging and joint mechanical testing data for next generation virtual knees.

Data in brief

Avec: Snehal Chokhandre , Erica E Neumann , Tara F Nagle , Robb W Colbrunn , Chris A Flask , Ceylan Colak , Jason Halloran , Ahmet Erdemir

A DNA-Based MRI Contrast Agent for Quantitative pH Measurement.

ACS sensors

Avec: Hyewon Seo , Kristine Y Ma , Erin E Tuttle , Isen Andrew C Calderon , Alissa D Buskermolen , Chris A Flask , Heather A Clark

pH-responsive i-motif-conjugated nanoparticles for MRI analysis.

Sensors & diagnostics

Avec: Kristine Y Ma , Mireia Perera-Gonzalez , Nicole I Langlois , Owen M Alzubi , Joseph D Guimond , Chris A Flask , Heather A Clark

Dynamic, Simultaneous Concentration Mapping of Multiple MRI Contrast Agents with Dual Contrast - Magnetic Resonance Fingerprinting.

Scientific reports

Avec: Christian E Anderson , Mette Johansen , Bernadette O Erokwu , He Hu , Yuning Gu , Yifan Zhang , Michael Kavran , Jason Vincent , Mitchell L Drumm , Mark A Griswold , Nicole F Steinmetz , Ming Li , Heather Clark , Rebecca J Darrah , Xin Yu , Susann M Brady-Kalnay , Chris A Flask

Exercise Training Rapidly Increases Hepatic Insulin Extraction in NAFLD.

Medicine and science in sports and exercise

Avec: Adithya Hari , Ciaràn E Fealy , Christopher L Axelrod , Jacob M Haus , Chris A Flask , Arthur J McCullough , John P Kirwan

Non-invasive assessment of hepatic lipid subspecies matched with non-alcoholic fatty liver disease phenotype.

Nutrition, metabolism, and cardiovascular diseases : NMCD

Avec: Melissa L Erickson , Jacob M Haus , Steven K Malin , Chris A Flask , Arthur J McCullough , John P Kirwan

Functionalized Phenylbenzamides Inhibit Aquaporin-4 Reducing Cerebral Edema and Improving Outcome in Two Models of CNS Injury.

Neuroscience

Avec: George W Farr , Christopher H Hall , Susan M Farr , Ramon Wade , Joshua M Detzel , Amielia G Adams , Jasen M Buch , Derek L Beahm , Christopher A Flask , Kui Xu , Joseph C LaManna , Paul R McGuirk , Walter F Boron , Marc F Pelletier

Neurovascular and cortical responses to hyperoxia: enhanced cognition and electroencephalographic activity despite reduced perfusion.

The Journal of physiology

Avec: Elizabeth G Damato , Tod A Flak , Ryan S Mayes , Kingman P Strohl , Aemilee M Ziganti , Alireza Abdollahifar , Chris A Flask , Joseph C LaManna , Michael J Decker

Lumacaftor/ivacaftor therapy is associated with reduced hepatic steatosis in cystic fibrosis patients.

World journal of hepatology

Avec: Katherine Kutney , Shannon B Donnola , Chris A Flask , Rose Gubitosi-Klug , MaryAnn O'Riordan , Kimberly McBennett , Thomas J Sferra , Beth Kaminski

Targeted Radiosensitizers for MR-Guided Radiation Therapy of Prostate Cancer.

Nano letters

Avec: Dong Luo , Andrew Johnson , Xinning Wang , Hao Li , Bernadette O Erokwu , Sarah Springer , Jason Lou , Gopalakrishnan Ramamurthy , Chris A Flask , Clemens Burda , Thomas J Meade , James P Basilion

Stromal derived factor-1 plasmid as a novel injection for treatment of stress urinary incontinence in a rat model.

International urogynecology journal

Avec: Ahmad O Khalifa , Michael Kavran , Amr Mahran , Ilaha Isali , Juliana Woda , Chris A Flask , Marc S Penn , Adonis K Hijaz

Limited nutrient availability in the tumor microenvironment renders pancreatic tumors sensitive to allosteric IDH1 inhibitors.

Nature cancer

Avec: Ali Vaziri-Gohar , Joel Cassel , Farheen S Mohammed , Mehrdad Zarei , Jonathan J Hue , Omid Hajihassani , Hallie J Graor , Yellamelli V V Srikanth , Saadia A Karim , Ata Abbas , Erin Prendergast , Vanessa Chen , Erryk S Katayama , Katerina Dukleska , Imran Khokhar , Anthony Andren , Li Zhang , Chunying Wu , Bernadette Erokwu , Chris A Flask , Mahsa Zarei , Rui Wang , Luke D Rothermel , Andrea M P Romani , Jessica Bowers , Robert Getts , Curtis Tatsuoka , Jennifer P Morton , Ilya Bederman , Henri Brunengraber , Costas A Lyssiotis , Joseph M Salvino , Jonathan R Brody , Jordan M Winter

Protein tyrosine phosphatase receptor δ serves as the orexigenic asprosin receptor.

Cell metabolism

Avec: Ila Mishra , Wei Rose Xie , Juan C Bournat , Yang He , Chunmei Wang , Elizabeth Sabath Silva , Hailan Liu , Zhiqiang Ku , Yinghua Chen , Bernadette O Erokwu , Peilin Jia , Zhongming Zhao , Zhiqiang An , Chris A Flask , Yanlin He , Yong Xu , Atul R Chopra

3D MR Fingerprinting for Dynamic Contrast-Enhanced Imaging of Whole Mouse Brain.

ArXiv

Avec: Yuran Zhu , Guanhua Wang , Yuning Gu , Walter Zhao , Jiahao Lu , Junqing Zhu , Christina J MacAskill , Andrew Dupuis , Mark A Griswold , Dan Ma , Chris A Flask , Xin Yu

Lung T1 MRI assessments in children with mild cystic fibrosis lung disease.

Pediatric pulmonology

Avec: Clement L Ren , Samya Z Nasr , James E Slaven , Aparna Joshi , Maryam Ghadimi Mahani , Charles Clem , Matthew Cooper , Susan Farr , Christina J MacAskill , Elise Keshock , Jennifer L Nicholas , Matthew Ferrebee , Kimberly McBennett , Chris A Flask

Fast quantitative MRI: Spiral Acquisition Matching-Based Algorithm (SAMBA) for Robust T

Journal of magnetic resonance open

Avec: Mireia Perera-Gonzalez , Christina J MacAskill , Heather A Clark , Chris A Flask

Réseau de co-auteurs

Bernadette O Erokwu 7 collaborations

Christina J MacAskill 6 collaborations

Xin Yu 5 collaborations

Mark A Griswold 4 collaborations

Dan Ma 4 collaborations

Yuning Gu 4 collaborations

Christopher A Flask 3 collaborations

Susan Farr 3 collaborations

Kimberly McBennett 3 collaborations

Mitchell L Drumm 3 collaborations

Yuran Zhu 3 collaborations

Guanhua Wang 3 collaborations

Michael Kavran 3 collaborations

Yifan Zhang 3 collaborations

Arthur J McCullough 3 collaborations

John P Kirwan 3 collaborations

Joseph C LaManna 3 collaborations

Heather A Clark 3 collaborations

Michael Markley 2 collaborations

Ashlee Parsons 2 collaborations

Katherine Kutney 2 collaborations

Katherine M Dell 2 collaborations

Yong Chen 2 collaborations

Rebecca J Darrah 2 collaborations

Christian E Anderson 2 collaborations

Melissa L Erickson 2 collaborations

Christopher L Axelrod 2 collaborations

Maryam Ghadimi Mahani 2 collaborations

Samya Z Nasr 2 collaborations

Walter Zhao 2 collaborations

Jiahao Lu 2 collaborations

Junqing Zhu 2 collaborations

Andrew Dupuis 2 collaborations

Kui Xu 2 collaborations

George W Farr 2 collaborations

Walter F Boron 2 collaborations

Jason Vincent 2 collaborations

Susann M Brady-Kalnay 2 collaborations

Kristine Y Ma 2 collaborations

Mireia Perera-Gonzalez 2 collaborations

Jacob M Haus 2 collaborations

Catherine A Mayer 1 collaboration

Abhrajit Ganguly 1 collaboration

Aubrey Mayer 1 collaboration

Christina M Pabelick 1 collaboration

Y S Prakash 1 collaboration

Vince C Hascall 1 collaboration

Ron J Midura 1 collaboration

Valbona Cali 1 collaboration

Richard J Martin 1 collaboration

Peter M MacFarlane 1 collaboration

Jacob R Perino 1 collaboration

Nicole Pritts 1 collaboration

Chaitanya Kolluru 1 collaboration

Huiyun Gao 1 collaboration

Jing Zhang 1 collaboration

Yunmei Wang 1 collaboration

David L Wilson 1 collaboration

Xiaofeng Zhu 1 collaboration

Karen Schelde 1 collaboration

Julie Rosenjack 1 collaboration

Claire Sonneborn 1 collaboration

Anjum Jafri 1 collaboration

Sarah Brumbaugh 1 collaboration

Arne Rietsch 1 collaboration

Craig A Hodges 1 collaboration

Thomas J Kelley 1 collaboration

Uyen Tran 1 collaboration

Suraj Serai 1 collaboration

Erum A Hartung 1 collaboration

Oliver Wessely 1 collaboration

Jacob T Mey 1 collaboration

William T King 1 collaboration

Fatima Neemuchwala 1 collaboration

Yuxi Pang 1 collaboration

Eunjee Lee 1 collaboration

Timothy D Johnson 1 collaboration

Craig J Galbán 1 collaboration

Aleksa B Fortuna 1 collaboration

Ramon Sanchez-Jacob 1 collaboration

Yuchi Liu 1 collaboration

Pan Zhao 1 collaboration

Ciro Ramos-Estebanez 1 collaboration

Gil Covarrubias 1 collaboration

Mette L Johansen 1 collaboration

Sonya E L Craig 1 collaboration

Abdelrahman Rahmy 1 collaboration

Anthony Cha 1 collaboration

Morgan Lorkowski 1 collaboration

Christina MacAskill 1 collaboration

Bryan Scott 1 collaboration

Madhusudhana Gargesha 1 collaboration

Debashish Roy 1 collaboration

Efstathios Karathanasis 1 collaboration

Snehal Chokhandre 1 collaboration

Erica E Neumann 1 collaboration

Tara F Nagle 1 collaboration

Robb W Colbrunn 1 collaboration

Ceylan Colak 1 collaboration

Jason Halloran 1 collaboration

Ahmet Erdemir 1 collaboration

Hyewon Seo 1 collaboration

Erin E Tuttle 1 collaboration

Isen Andrew C Calderon 1 collaboration

Alissa D Buskermolen 1 collaboration

Nicole I Langlois 1 collaboration

Owen M Alzubi 1 collaboration

Joseph D Guimond 1 collaboration

Mette Johansen 1 collaboration

He Hu 1 collaboration

Nicole F Steinmetz 1 collaboration

Ming Li 1 collaboration

Heather Clark 1 collaboration

Adithya Hari 1 collaboration

Ciaràn E Fealy 1 collaboration

Steven K Malin 1 collaboration

Christopher H Hall 1 collaboration

Susan M Farr 1 collaboration

Ramon Wade 1 collaboration

Joshua M Detzel 1 collaboration

Amielia G Adams 1 collaboration

Jasen M Buch 1 collaboration

Derek L Beahm 1 collaboration

Paul R McGuirk 1 collaboration

Marc F Pelletier 1 collaboration

Elizabeth G Damato 1 collaboration

Tod A Flak 1 collaboration

Ryan S Mayes 1 collaboration

Kingman P Strohl 1 collaboration

Aemilee M Ziganti 1 collaboration

Alireza Abdollahifar 1 collaboration

Michael J Decker 1 collaboration

Shannon B Donnola 1 collaboration

Rose Gubitosi-Klug 1 collaboration

MaryAnn O'Riordan 1 collaboration

Thomas J Sferra 1 collaboration

Beth Kaminski 1 collaboration

Dong Luo 1 collaboration

Andrew Johnson 1 collaboration

Xinning Wang 1 collaboration

Hao Li 1 collaboration

Sarah Springer 1 collaboration

Jason Lou 1 collaboration

Gopalakrishnan Ramamurthy 1 collaboration

Clemens Burda 1 collaboration

Thomas J Meade 1 collaboration

James P Basilion 1 collaboration

Ahmad O Khalifa 1 collaboration

Amr Mahran 1 collaboration

Ilaha Isali 1 collaboration

Juliana Woda 1 collaboration

Marc S Penn 1 collaboration

Adonis K Hijaz 1 collaboration

Ali Vaziri-Gohar 1 collaboration

Joel Cassel 1 collaboration

Farheen S Mohammed 1 collaboration

Mehrdad Zarei 1 collaboration

Jonathan J Hue 1 collaboration

Omid Hajihassani 1 collaboration

Hallie J Graor 1 collaboration

Yellamelli V V Srikanth 1 collaboration

Saadia A Karim 1 collaboration

Ata Abbas 1 collaboration

Erin Prendergast 1 collaboration

Vanessa Chen 1 collaboration

Erryk S Katayama 1 collaboration

Katerina Dukleska 1 collaboration

Imran Khokhar 1 collaboration

Anthony Andren 1 collaboration

Li Zhang 1 collaboration

Chunying Wu 1 collaboration

Bernadette Erokwu 1 collaboration

Mahsa Zarei 1 collaboration

Rui Wang 1 collaboration

Luke D Rothermel 1 collaboration

Andrea M P Romani 1 collaboration

Jessica Bowers 1 collaboration

Robert Getts 1 collaboration

Curtis Tatsuoka 1 collaboration

Jennifer P Morton 1 collaboration

Ilya Bederman 1 collaboration

Henri Brunengraber 1 collaboration

Costas A Lyssiotis 1 collaboration

Joseph M Salvino 1 collaboration

Jonathan R Brody 1 collaboration

Jordan M Winter 1 collaboration

Ila Mishra 1 collaboration

Wei Rose Xie 1 collaboration

Juan C Bournat 1 collaboration

Yang He 1 collaboration

Chunmei Wang 1 collaboration

Elizabeth Sabath Silva 1 collaboration

Hailan Liu 1 collaboration

Zhiqiang Ku 1 collaboration

Yinghua Chen 1 collaboration

Peilin Jia 1 collaboration

Zhongming Zhao 1 collaboration

Zhiqiang An 1 collaboration

Yanlin He 1 collaboration

Yong Xu 1 collaboration

Atul R Chopra 1 collaboration

Clement L Ren 1 collaboration

James E Slaven 1 collaboration

Aparna Joshi 1 collaboration

Charles Clem 1 collaboration

Matthew Cooper 1 collaboration

Elise Keshock 1 collaboration

Jennifer L Nicholas 1 collaboration

Matthew Ferrebee 1 collaboration