Christoph Helwig

Affiliations

Merck KGaA, Darmstadt, Germany.

Publications (14)

Bintrafusp alfa (M7824), a bifunctional fusion protein targeting TGF-β and PD-L1: results from a phase I expansion cohort in patients with recurrent glioblastoma.

Neuro-oncology advances

Avec: Mustafa Khasraw , Michael Weller , David Lorente , Kathryn Kolibaba , Chee Khoon Lee , Craig Gedye , Macarena I de La Fuente , David Vicente , David A Reardon , Hui K Gan , Andrew M Scott , Isabelle Dussault , Christoph Helwig , Laureen S Ojalvo , Carole Gourmelon , Morris Groves

Risk assessment of drug-drug interaction potential for bintrafusp alfa with cytochrome P4503A4 substrates: A totality of evidence approach.

Clinical and translational science

Avec: Yulia Vugmeyster , George Locke , Christoph Helwig , P Alexander Rolfe , Jennifer Q Dong , Karthik Venkatakrishnan

Comparative effectiveness of gonadotropins used for ovarian stimulation during assisted reproductive technologies (ART) in France: A real-world observational study from the French nationwide claims database (SNDS).

Best practice & research. Clinical obstetrics & gynaecology

Avec: M Grynberg , I Cedrin-Durnerin , F Raguideau , E Herquelot , L Luciani , F Porte , P Verpillat , C Helwig , J E Schwarze , S Paillet , C Castello-Bridoux , Thomas D'Hooghe , M Benchaïb

Programmed Death-Ligand 1 Immunohistochemistry Assay Comparison Studies in NSCLC: Characterization of the 73-10 Assay.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Hans Juergen Grote , Zheng Feng , Michael Schlichting , Christoph Helwig , Mary Ruisi , Hulin Jin , Juergen Scheuenpflug , Claudia-Nanette Gann , Zhen Su , Martin Reck , Everett E Vokes , Keith M Kerr

Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Second-Line Treatment of Patients With NSCLC: Results From an Expansion Cohort of a Phase 1 Trial.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Luis Paz-Ares , Tae Min Kim , David Vicente , Enriqueta Felip , Dae Ho Lee , Ki Hyeong Lee , Chia-Chi Lin , Maria Jose Flor , Massimo Di Nicola , Rosa Maria Alvarez , Isabelle Dussault , Christoph Helwig , Laureen S Ojalvo , James L Gulley , Byoung Chul Cho

Breast Cancer and SARS-Cov2: Lessons from a Pandemic.

Anticancer research

Avec: Marie Gosset , Jocelyn Gal , Renaud Schiappa , Christopher Helwig , Iris Bonomo , Yann Delpech , Emmanuel Barranger

Safety and Tolerability of Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGFβ and PD-L1, in Asian Patients with Pretreated Recurrent or Refractory Gastric Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Yoon-Koo Kang , Yung-Jue Bang , Shunsuke Kondo , Hyun Cheol Chung , Kei Muro , Isabelle Dussault , Christoph Helwig , Motonobu Osada , Toshihiko Doi

Phase I Study of the Bifunctional Fusion Protein Bintrafusp Alfa in Asian Patients with Advanced Solid Tumors, Including a Hepatocellular Carcinoma Safety-Assessment Cohort.

The oncologist

Avec: Toshihiko Doi , Yutaka Fujiwara , Takafumi Koyama , Masafumi Ikeda , Christoph Helwig , Morihiro Watanabe , Yulia Vugmeyster , Masatoshi Kudo

Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Patients With Non-Small Cell Lung Cancer Resistant or Refractory to Immune Checkpoint Inhibitors.

The oncologist

Avec: Fabrice Barlesi , Nicolas Isambert , Enriqueta Felip , Byoung Chul Cho , Dae Ho Lee , Julio Peguero , Guy Jerusalem , Nicolas Penel , Esma Saada-Bouzid , Pilar Garrido , Christoph Helwig , George Locke , Laureen S Ojalvo , James L Gulley

Zygomatic air cells in connection with Luc's abscess.

International journal of pediatric otorhinolaryngology

Avec: Steven Engebretsen , Tyler Patrick , Cecelia Helwig , Mallory O'Niel

Phase I study of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with pretreated biliary tract cancer.

Journal for immunotherapy of cancer

Avec: Changhoon Yoo , Do-Youn Oh , Hye Jin Choi , Masatoshi Kudo , Makoto Ueno , Shunsuke Kondo , Li-Tzong Chen , Motonobu Osada , Christoph Helwig , Isabelle Dussault , Masafumi Ikeda

Bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in advanced squamous cell carcinoma of the head and neck: results from a phase I cohort.

Journal for immunotherapy of cancer

Avec: Byoung Chul Cho , Amaury Daste , Alain Ravaud , Sébastien Salas , Nicolas Isambert , Edward McClay , Ahmad Awada , Christian Borel , Laureen S Ojalvo , Christoph Helwig , P Alexander Rolfe , James L Gulley , Nicolas Penel

Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGFβ and PD-L1, in Patients with Esophageal Squamous Cell Carcinoma: Results from a Phase 1 Cohort in Asia.

Targeted oncology

Avec: Chia-Chi Lin , Toshihiko Doi , Kei Muro , Ming-Mo Hou , Taito Esaki , Hiroki Hara , Hyun Cheol Chung , Christoph Helwig , Isabelle Dussault , Motonobu Osada , Shunsuke Kondo

Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Patients with Esophageal Adenocarcinoma: Results from a Phase 1 Cohort.

Targeted oncology

Avec: Benjamin Tan , Adnan Khattak , Enriqueta Felip , Karen Kelly , Patricia Rich , Ding Wang , Christoph Helwig , Isabelle Dussault , Laureen S Ojalvo , Nicolas Isambert

Réseau de co-auteurs

Isabelle Dussault 6 collaborations

Laureen S Ojalvo 5 collaborations

Enriqueta Felip 3 collaborations

James L Gulley 3 collaborations

Byoung Chul Cho 3 collaborations

Shunsuke Kondo 3 collaborations

Motonobu Osada 3 collaborations

Toshihiko Doi 3 collaborations

Nicolas Isambert 3 collaborations

David Vicente 2 collaborations

Yulia Vugmeyster 2 collaborations

George Locke 2 collaborations

P Alexander Rolfe 2 collaborations

Dae Ho Lee 2 collaborations

Chia-Chi Lin 2 collaborations

Hyun Cheol Chung 2 collaborations

Kei Muro 2 collaborations

Masafumi Ikeda 2 collaborations

Masatoshi Kudo 2 collaborations

Nicolas Penel 2 collaborations

Mustafa Khasraw 1 collaboration

Michael Weller 1 collaboration

David Lorente 1 collaboration

Kathryn Kolibaba 1 collaboration

Chee Khoon Lee 1 collaboration

Craig Gedye 1 collaboration

Macarena I de La Fuente 1 collaboration

David A Reardon 1 collaboration

Hui K Gan 1 collaboration

Andrew M Scott 1 collaboration

Carole Gourmelon 1 collaboration

Morris Groves 1 collaboration

Jennifer Q Dong 1 collaboration

Karthik Venkatakrishnan 1 collaboration

M Grynberg 1 collaboration

I Cedrin-Durnerin 1 collaboration

F Raguideau 1 collaboration

E Herquelot 1 collaboration

L Luciani 1 collaboration

F Porte 1 collaboration

P Verpillat 1 collaboration

C Helwig 1 collaboration

J E Schwarze 1 collaboration

S Paillet 1 collaboration

C Castello-Bridoux 1 collaboration

Thomas D'Hooghe 1 collaboration

M Benchaïb 1 collaboration

Hans Juergen Grote 1 collaboration

Zheng Feng 1 collaboration

Michael Schlichting 1 collaboration

Mary Ruisi 1 collaboration

Hulin Jin 1 collaboration

Juergen Scheuenpflug 1 collaboration

Claudia-Nanette Gann 1 collaboration

Zhen Su 1 collaboration

Martin Reck 1 collaboration

Everett E Vokes 1 collaboration

Keith M Kerr 1 collaboration

Luis Paz-Ares 1 collaboration

Tae Min Kim 1 collaboration

Ki Hyeong Lee 1 collaboration

Maria Jose Flor 1 collaboration

Massimo Di Nicola 1 collaboration

Rosa Maria Alvarez 1 collaboration

Marie Gosset 1 collaboration

Jocelyn Gal 1 collaboration

Renaud Schiappa 1 collaboration

Christopher Helwig 1 collaboration

Iris Bonomo 1 collaboration

Yann Delpech 1 collaboration

Emmanuel Barranger 1 collaboration

Yoon-Koo Kang 1 collaboration

Yung-Jue Bang 1 collaboration

Yutaka Fujiwara 1 collaboration

Takafumi Koyama 1 collaboration

Morihiro Watanabe 1 collaboration

Fabrice Barlesi 1 collaboration

Julio Peguero 1 collaboration

Guy Jerusalem 1 collaboration

Esma Saada-Bouzid 1 collaboration

Pilar Garrido 1 collaboration

Steven Engebretsen 1 collaboration

Tyler Patrick 1 collaboration

Cecelia Helwig 1 collaboration

Mallory O'Niel 1 collaboration

Changhoon Yoo 1 collaboration

Do-Youn Oh 1 collaboration

Hye Jin Choi 1 collaboration

Makoto Ueno 1 collaboration

Li-Tzong Chen 1 collaboration

Amaury Daste 1 collaboration

Alain Ravaud 1 collaboration

Sébastien Salas 1 collaboration

Edward McClay 1 collaboration

Ahmad Awada 1 collaboration

Christian Borel 1 collaboration

Ming-Mo Hou 1 collaboration

Taito Esaki 1 collaboration

Hiroki Hara 1 collaboration

Benjamin Tan 1 collaboration

Adnan Khattak 1 collaboration

Karen Kelly 1 collaboration

Patricia Rich 1 collaboration

Ding Wang 1 collaboration