Isabelle Dussault

Affiliations

EMD Serono Inc, Billerica, MA, USA.

Publications (10)

Population Pharmacokinetic Analysis of Bintrafusp Alfa in Different Cancer Types.

Advances in therapy

Avec: Justin J Wilkins , Yulia Vugmeyster , Isabelle Dussault , Pascal Girard , Akash Khandelwal

Bintrafusp alfa (M7824), a bifunctional fusion protein targeting TGF-β and PD-L1: results from a phase I expansion cohort in patients with recurrent glioblastoma.

Neuro-oncology advances

Avec: Mustafa Khasraw , Michael Weller , David Lorente , Kathryn Kolibaba , Chee Khoon Lee , Craig Gedye , Macarena I de La Fuente , David Vicente , David A Reardon , Hui K Gan , Andrew M Scott , Isabelle Dussault , Christoph Helwig , Laureen S Ojalvo , Carole Gourmelon , Morris Groves

Safety and Tolerability of Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGFβ and PD-L1, in Asian Patients with Pretreated Recurrent or Refractory Gastric Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Yoon-Koo Kang , Yung-Jue Bang , Shunsuke Kondo , Hyun Cheol Chung , Kei Muro , Isabelle Dussault , Christoph Helwig , Motonobu Osada , Toshihiko Doi

Discovery of

Journal of medicinal chemistry

Avec: Michael H Reutershan , Michelle R Machacek , Michael D Altman , Stephane Bogen , Mingmei Cai , Carolyn Cammarano , Dapeng Chen , Matthew Christopher , John Cryan , Pierre Daublain , Xavier Fradera , Prasanthi Geda , Peter Goldenblatt , Armetta D Hill , Raymond A Kemper , Victoria Kutilek , Chaomin Li , Michelle Martinez , Mark McCoy , Latha Nair , Weidong Pan , Christopher F Thompson , Giovanna Scapin , Manami Shizuka , Marianne L Spatz , Dietrich Steinhuebel , Binyuan Sun , Matthew E Voss , Xiao Wang , Liping Yang , Tammie C Yeh , Isabelle Dussault , C Gary Marshall , B Wesley Trotter

Selection of the Recommended Phase 2 Dose for Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1.

Clinical pharmacology and therapeutics

Avec: Yulia Vugmeyster , Justin Wilkins , Andre Koenig , Samer El Bawab , Isabelle Dussault , Laureen S Ojalvo , Samrita De Banerjee , Lena Klopp-Schulze , Akash Khandelwal

Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Second-Line Treatment of Patients With NSCLC: Results From an Expansion Cohort of a Phase 1 Trial.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Avec: Luis Paz-Ares , Tae Min Kim , David Vicente , Enriqueta Felip , Dae Ho Lee , Ki Hyeong Lee , Chia-Chi Lin , Maria Jose Flor , Massimo Di Nicola , Rosa Maria Alvarez , Isabelle Dussault , Christoph Helwig , Laureen S Ojalvo , James L Gulley , Byoung Chul Cho

Dual inhibition of TGF-β and PD-L1: a novel approach to cancer treatment.

Molecular oncology

Avec: James L Gulley , Jeffrey Schlom , Mary Helen Barcellos-Hoff , Xiao-Jing Wang , Joan Seoane , Francois Audhuy , Yan Lan , Isabelle Dussault , Aristidis Moustakas

Phase I study of bintrafusp alfa, a bifunctional fusion protein targeting TGF-β and PD-L1, in patients with pretreated biliary tract cancer.

Journal for immunotherapy of cancer

Avec: Changhoon Yoo , Do-Youn Oh , Hye Jin Choi , Masatoshi Kudo , Makoto Ueno , Shunsuke Kondo , Li-Tzong Chen , Motonobu Osada , Christoph Helwig , Isabelle Dussault , Masafumi Ikeda

Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGFβ and PD-L1, in Patients with Esophageal Squamous Cell Carcinoma: Results from a Phase 1 Cohort in Asia.

Targeted oncology

Avec: Chia-Chi Lin , Toshihiko Doi , Kei Muro , Ming-Mo Hou , Taito Esaki , Hiroki Hara , Hyun Cheol Chung , Christoph Helwig , Isabelle Dussault , Motonobu Osada , Shunsuke Kondo

Bintrafusp Alfa, a Bifunctional Fusion Protein Targeting TGF-β and PD-L1, in Patients with Esophageal Adenocarcinoma: Results from a Phase 1 Cohort.

Targeted oncology

Avec: Benjamin Tan , Adnan Khattak , Enriqueta Felip , Karen Kelly , Patricia Rich , Ding Wang , Christoph Helwig , Isabelle Dussault , Laureen S Ojalvo , Nicolas Isambert

Réseau de co-auteurs

Christoph Helwig 6 collaborations

Laureen S Ojalvo 4 collaborations

Shunsuke Kondo 3 collaborations

Motonobu Osada 3 collaborations

Yulia Vugmeyster 2 collaborations

Akash Khandelwal 2 collaborations

David Vicente 2 collaborations

Hyun Cheol Chung 2 collaborations

Kei Muro 2 collaborations

Toshihiko Doi 2 collaborations

Enriqueta Felip 2 collaborations

Chia-Chi Lin 2 collaborations

James L Gulley 2 collaborations

Justin J Wilkins 1 collaboration

Pascal Girard 1 collaboration

Mustafa Khasraw 1 collaboration

Michael Weller 1 collaboration

David Lorente 1 collaboration

Kathryn Kolibaba 1 collaboration

Chee Khoon Lee 1 collaboration

Craig Gedye 1 collaboration

Macarena I de La Fuente 1 collaboration

David A Reardon 1 collaboration

Hui K Gan 1 collaboration

Andrew M Scott 1 collaboration

Carole Gourmelon 1 collaboration

Morris Groves 1 collaboration

Yoon-Koo Kang 1 collaboration

Yung-Jue Bang 1 collaboration

Michael H Reutershan 1 collaboration

Michelle R Machacek 1 collaboration

Michael D Altman 1 collaboration

Stephane Bogen 1 collaboration

Mingmei Cai 1 collaboration

Carolyn Cammarano 1 collaboration

Dapeng Chen 1 collaboration

Matthew Christopher 1 collaboration

John Cryan 1 collaboration

Pierre Daublain 1 collaboration

Xavier Fradera 1 collaboration

Prasanthi Geda 1 collaboration

Peter Goldenblatt 1 collaboration

Armetta D Hill 1 collaboration

Raymond A Kemper 1 collaboration

Victoria Kutilek 1 collaboration

Chaomin Li 1 collaboration

Michelle Martinez 1 collaboration

Mark McCoy 1 collaboration

Latha Nair 1 collaboration

Weidong Pan 1 collaboration

Christopher F Thompson 1 collaboration

Giovanna Scapin 1 collaboration

Manami Shizuka 1 collaboration

Marianne L Spatz 1 collaboration

Dietrich Steinhuebel 1 collaboration

Binyuan Sun 1 collaboration

Matthew E Voss 1 collaboration

Xiao Wang 1 collaboration

Liping Yang 1 collaboration

Tammie C Yeh 1 collaboration

C Gary Marshall 1 collaboration

B Wesley Trotter 1 collaboration

Justin Wilkins 1 collaboration

Andre Koenig 1 collaboration

Samer El Bawab 1 collaboration

Samrita De Banerjee 1 collaboration

Lena Klopp-Schulze 1 collaboration

Luis Paz-Ares 1 collaboration

Tae Min Kim 1 collaboration

Dae Ho Lee 1 collaboration

Ki Hyeong Lee 1 collaboration

Maria Jose Flor 1 collaboration

Massimo Di Nicola 1 collaboration

Rosa Maria Alvarez 1 collaboration

Byoung Chul Cho 1 collaboration

Jeffrey Schlom 1 collaboration

Mary Helen Barcellos-Hoff 1 collaboration

Xiao-Jing Wang 1 collaboration

Joan Seoane 1 collaboration

Francois Audhuy 1 collaboration

Yan Lan 1 collaboration

Aristidis Moustakas 1 collaboration

Changhoon Yoo 1 collaboration

Do-Youn Oh 1 collaboration

Hye Jin Choi 1 collaboration

Masatoshi Kudo 1 collaboration

Makoto Ueno 1 collaboration

Li-Tzong Chen 1 collaboration

Masafumi Ikeda 1 collaboration

Ming-Mo Hou 1 collaboration

Taito Esaki 1 collaboration

Hiroki Hara 1 collaboration

Benjamin Tan 1 collaboration

Adnan Khattak 1 collaboration

Karen Kelly 1 collaboration

Patricia Rich 1 collaboration

Ding Wang 1 collaboration

Nicolas Isambert 1 collaboration