Peter Goldenblatt

Affiliations

In Vitro Pharmacology, Merck & Co., Inc., 33 Avenue Louis Pasteur, Boston, Massachusetts 02115 United States.

Publications (8)

Projected Dose Optimization of Amino- and Hydroxypyrrolidine Purine PI3Kδ Immunomodulators.

Journal of medicinal chemistry

Avec: Joey L Methot , Hua Zhou , Meredeth A McGowan , Neville John Anthony , Matthew Christopher , Yudith Garcia , Abdelghani Achab , Kathryn Lipford , Benjamin Wesley Trotter , Michael D Altman , Xavier Fradera , Charles A Lesburg , Chaomin Li , Stephen Alves , Craig P Chappell , Renu Jain , Ruban Mangado , Elaine Pinheiro , Sybill M G Williams , Peter Goldenblatt , Armetta Hill , Lynsey Shaffer , Dapeng Chen , Vincent Tong , Robbie L McLeod , Hyun-Hee Lee , Hongshi Yu , Sanjiv Shah , Jason D Katz

Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability.

Journal of medicinal chemistry

Avec: Joey L Methot , Hua Zhou , Sam D Kattar , Meredeth A McGowan , Kevin Wilson , Yudith Garcia , Yongi Deng , Michael Altman , Xavier Fradera , Charles Lesburg , Thierry Fischmann , Chaomin Li , Steve Alves , Sanjiv Shah , Rafael Fernandez , Peter Goldenblatt , Armetta Hill , Lynsey Shaffer , Dapeng Chen , Vince Tong , Robbie L McLeod , Hongshi Yu , Alan Bass , Ray Kemper , Nicholas T Gatto , Lisa LaFranco-Scheuch , Benjamin Wesley Trotter , Timothy Guzi , Jason D Katz

Discovery and characterization of novel peptide inhibitors of the NRF2/MAFG/DNA ternary complex for the treatment of cancer.

European journal of medicinal chemistry

Avec: Vladimir Simov , Michael D Altman , Elisabetta Bianchi , Sonia DelRizzo , Edward N DiNunzio , Guo Feng , Peter Goldenblatt , Raffaele Ingenito , Scott A Johnson , My Sam Mansueto , Todd Mayhood , Jonathan D Mortison , Victor Serebrov , Christopher Sondey , Venkat Sriraman , Thomas J Tucker , Abbas Walji , Hui Wan , Yingzi Yue , Alexander Stoeck , Erin F DiMauro

Optimization of Versatile Oxindoles as Selective PI3Kδ Inhibitors.

ACS medicinal chemistry letters

Avec: Joey L Methot , Abdelghani Achab , Matthew Christopher , Hua Zhou , Meredeth A McGowan , B Wesley Trotter , Xavier Fradera , Charles A Lesburg , Peter Goldenblatt , Armetta Hill , Dapeng Chen , Karin M Otte , Martin Augustin , Sanjiv Shah , Jason D Katz

Discovery of a new series of PI3K-δ inhibitors from Virtual Screening.

Bioorganic & medicinal chemistry letters

Avec: Xavier Fradera , Qiaolin Deng , Abdelganhi Achab , Yudith Garcia , Solomon D Kattar , Meredeth A McGowan , Joey L Methot , Kevin Wilson , Hua Zhou , Lynsey Shaffer , Peter Goldenblatt , Vincent Tong , Martin A Augustin , Michael D Altman , Charles A Lesburg , Sanjiv Shah , Jason D Katz

Design of selective PI3Kδ inhibitors using an iterative scaffold-hopping workflow.

Bioorganic & medicinal chemistry letters

Avec: Xavier Fradera , Joey L Methot , Abdelghani Achab , Matthew Christopher , Michael D Altman , Hua Zhou , Meredeth A McGowan , Sam D Kattar , Kevin Wilson , Yudith Garcia , Martin A Augustin , Charles A Lesburg , Sanjiv Shah , Peter Goldenblatt , Jason D Katz

Discovery and optimization of heteroaryl piperazines as potent and selective PI3Kδ inhibitors.

Bioorganic & medicinal chemistry letters

Avec: Hua Zhou , Meredeth A McGowan , Kathryn Lipford , Matthew Christopher , Xavier Fradera , David Witter , Charles A Lesburg , Chaomin Li , Joey L Methot , John Lampe , Abdelghani Achab , Lynsey Shaffer , Peter Goldenblatt , Sanjiv Shah , Alan Bass , Gottfried Schroeder , Dapeng Chen , Haoyu Zeng , Martin A Augustin , Jason D Katz

Discovery of

Journal of medicinal chemistry

Avec: Michael H Reutershan , Michelle R Machacek , Michael D Altman , Stephane Bogen , Mingmei Cai , Carolyn Cammarano , Dapeng Chen , Matthew Christopher , John Cryan , Pierre Daublain , Xavier Fradera , Prasanthi Geda , Peter Goldenblatt , Armetta D Hill , Raymond A Kemper , Victoria Kutilek , Chaomin Li , Michelle Martinez , Mark McCoy , Latha Nair , Weidong Pan , Christopher F Thompson , Giovanna Scapin , Manami Shizuka , Marianne L Spatz , Dietrich Steinhuebel , Binyuan Sun , Matthew E Voss , Xiao Wang , Liping Yang , Tammie C Yeh , Isabelle Dussault , C Gary Marshall , B Wesley Trotter

Réseau de co-auteurs

Xavier Fradera 7 collaborations

Joey L Methot 6 collaborations

Hua Zhou 6 collaborations

Meredeth A McGowan 6 collaborations

Sanjiv Shah 6 collaborations

Jason D Katz 6 collaborations

Matthew Christopher 5 collaborations

Michael D Altman 5 collaborations

Charles A Lesburg 5 collaborations

Dapeng Chen 5 collaborations

Yudith Garcia 4 collaborations

Abdelghani Achab 4 collaborations

Chaomin Li 4 collaborations

Lynsey Shaffer 4 collaborations

Armetta Hill 3 collaborations

Kevin Wilson 3 collaborations

Martin A Augustin 3 collaborations

Kathryn Lipford 2 collaborations

Benjamin Wesley Trotter 2 collaborations

Vincent Tong 2 collaborations

Robbie L McLeod 2 collaborations

Hongshi Yu 2 collaborations

Sam D Kattar 2 collaborations

Alan Bass 2 collaborations

B Wesley Trotter 2 collaborations

Neville John Anthony 1 collaboration

Stephen Alves 1 collaboration

Craig P Chappell 1 collaboration

Renu Jain 1 collaboration

Ruban Mangado 1 collaboration

Elaine Pinheiro 1 collaboration

Sybill M G Williams 1 collaboration

Hyun-Hee Lee 1 collaboration

Yongi Deng 1 collaboration

Michael Altman 1 collaboration

Charles Lesburg 1 collaboration

Thierry Fischmann 1 collaboration

Steve Alves 1 collaboration

Rafael Fernandez 1 collaboration

Vince Tong 1 collaboration

Ray Kemper 1 collaboration

Nicholas T Gatto 1 collaboration

Lisa LaFranco-Scheuch 1 collaboration

Timothy Guzi 1 collaboration

Vladimir Simov 1 collaboration

Elisabetta Bianchi 1 collaboration

Sonia DelRizzo 1 collaboration

Edward N DiNunzio 1 collaboration

Guo Feng 1 collaboration

Raffaele Ingenito 1 collaboration

Scott A Johnson 1 collaboration

My Sam Mansueto 1 collaboration

Todd Mayhood 1 collaboration

Jonathan D Mortison 1 collaboration

Victor Serebrov 1 collaboration

Christopher Sondey 1 collaboration

Venkat Sriraman 1 collaboration

Thomas J Tucker 1 collaboration

Abbas Walji 1 collaboration

Hui Wan 1 collaboration

Yingzi Yue 1 collaboration

Alexander Stoeck 1 collaboration

Erin F DiMauro 1 collaboration

Karin M Otte 1 collaboration

Martin Augustin 1 collaboration

Qiaolin Deng 1 collaboration

Abdelganhi Achab 1 collaboration

Solomon D Kattar 1 collaboration

David Witter 1 collaboration

John Lampe 1 collaboration

Gottfried Schroeder 1 collaboration

Haoyu Zeng 1 collaboration

Michael H Reutershan 1 collaboration

Michelle R Machacek 1 collaboration

Stephane Bogen 1 collaboration

Mingmei Cai 1 collaboration

Carolyn Cammarano 1 collaboration

John Cryan 1 collaboration

Pierre Daublain 1 collaboration

Prasanthi Geda 1 collaboration

Armetta D Hill 1 collaboration

Raymond A Kemper 1 collaboration

Victoria Kutilek 1 collaboration

Michelle Martinez 1 collaboration

Mark McCoy 1 collaboration

Latha Nair 1 collaboration

Weidong Pan 1 collaboration

Christopher F Thompson 1 collaboration

Giovanna Scapin 1 collaboration

Manami Shizuka 1 collaboration

Marianne L Spatz 1 collaboration

Dietrich Steinhuebel 1 collaboration

Binyuan Sun 1 collaboration

Matthew E Voss 1 collaboration

Xiao Wang 1 collaboration

Liping Yang 1 collaboration

Tammie C Yeh 1 collaboration

Isabelle Dussault 1 collaboration

C Gary Marshall 1 collaboration