Christos Samakovlis

Affiliations

Science for Life Laboratory, Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, SE-10691, Stockholm, Sweden. christos.samakovlis@su.se.
Cardiopulmonary Institute, Justus Liebig University of Giessen, Giessen, Germany. christos.samakovlis@su.se.

ORCID: 0000-0002-9153-6040

Publications (22)

WASH activation controls endosomal recycling and EGFR and Hippo signaling during tumor-suppressive cell competition.

Nature communications

Avec: Dan Liu , Vasilios Tsarouhas , Christos Samakovlis

GLI1+ cells are a source of repair-supportive mesenchymal cells (RSMCs) during airway epithelial regeneration.

Cellular and molecular life sciences : CMLS

Avec: Xuran Chu , Arun Lingampally , Alena Moiseenko , Vahid Kheirollahi , Ana Ivonne Vazquez-Armendariz , Janine Koepke , Ali Khadim , Georgios Kiliaris , Mahtab Shahriari Felordi , Mahsa Zabihi , Irina Shalashova , Ioannis Alexopoulos , Stefan Günther , Kevin Lebrigand , Marin Truchi , Andreas Günther , Thomas Braun , Bernard Mari , Christos Samakovlis , Xiaokun Li , Werner Seeger , Susanne Herold , Jin-San Zhang , Saverio Bellusci , Elie El Agha

Regulation and role of the ER stress transcription factor CHOP in alveolar epithelial type-II cells.

Journal of molecular medicine (Berlin, Germany)

Avec: Oleksiy Klymenko , Martin Huehn , Jochen Wilhelm , Roxana Wasnick , Irina Shalashova , Clemens Ruppert , Ingrid Henneke , Stefanie Hezel , Katharina Guenther , Poornima Mahavadi , Christos Samakovlis , Werner Seeger , Andreas Guenther , Martina Korfei

An essential function for autocrine hedgehog signaling in epithelial proliferation and differentiation in the trachea.

Development (Cambridge, England)

Avec: Wenguang Yin , Andreas Liontos , Janine Koepke , Maroua Ghoul , Luciana Mazzocchi , Xinyuan Liu , Chunyan Lu , Haoyu Wu , Athanasios Fysikopoulos , Alexandros Sountoulidis , Werner Seeger , Clemens Ruppert , Andreas Günther , Didier Y R Stainier , Christos Samakovlis

The discovAIR project: a roadmap towards the Human Lung Cell Atlas.

The European respiratory journal

Avec: Malte D Luecken , Laure-Emmanuelle Zaragosi , Elo Madissoon , Lisa Sikkema , Alexandra B Firsova , Elena De Domenico , Louis Kümmerle , Adem Saglam , Marijn Berg , Aurore C A Gay , Janine Schniering , Christoph H Mayr , Xesús M Abalo , Ludvig Larsson , Alexandros Sountoulidis , Sarah A Teichmann , Karen van Eunen , Gerard H Koppelman , Kourosh Saeb-Parsy , Sylvie Leroy , Pippa Powell , Ugis Sarkans , Wim Timens , Joakim Lundeberg , Maarten van den Berge , Mats Nilsson , Peter Horváth , Jessica Denning , Irene Papatheodorou , Joachim L Schultze , Herbert B Schiller , Pascal Barbry , Ilya Petoukhov , Alexander V Misharin , Ian M Adcock , Michael von Papen , Fabian J Theis , Christos Samakovlis , Kerstin B Meyer , Martijn C Nawijn

FGF10 Triggers De Novo Alveologenesis in a Bronchopulmonary Dysplasia Model: Impact on Resident Mesenchymal Niche Cells.

Stem cells (Dayton, Ohio)

Avec: Sara Taghizadeh , Cho-Ming Chao , Stefan Guenther , Lea Glaser , Luisa Gersmann , Gabriela Michel , Simone Kraut , Kerstin Goth , Janine Koepke , Monika Heiner , Ana Ivonne Vazquez-Armendariz , Susanne Herold , Christos Samakovlis , Norbert Weissmann , Francesca Ricci , Giorgio Aquila , Laurent Boyer , Harald Ehrhardt , Parviz Minoo , Saverio Bellusci , Stefano Rivetti

A surfactant lipid layer of endosomal membranes facilitates airway gas filling in Drosophila.

Current biology : CB

Avec: Vasilios Tsarouhas , Dan Liu , Georgia Tsikala , Ylva Engström , Maura Strigini , Christos Samakovlis

A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension.

Nature communications

Avec: Swati Dabral , Christian Muecke , Chanil Valasarajan , Mario Schmoranzer , Astrid Wietelmann , Gregg L Semenza , Michael Meister , Thomas Muley , Tamina Seeger-Nukpezah , Christos Samakovlis , Norbert Weissmann , Friedrich Grimminger , Werner Seeger , Rajkumar Savai , Soni S Pullamsetti

Fgfr2b signaling is essential for the maintenance of the alveolar epithelial type 2 lineage during lung homeostasis in mice.

Cellular and molecular life sciences : CMLS

Avec: Negah Ahmadvand , Arun Lingampally , Farhad Khosravi , Ana Ivonne Vazquez-Armendariz , Stefano Rivetti , Matthew R Jones , Jochen Wilhelm , Susanne Herold , Guillermo Barreto , Janine Koepke , Christos Samakovlis , Gianni Carraro , Jin-San Zhang , Denise Al Alam , Saverio Bellusci

Sfrp1 inhibits lung fibroblast invasion during transition to injury induced myofibroblasts.

The European respiratory journal

Avec: Christoph H Mayr , Arunima Sengupta , Sara Asgharpour , Meshal Ansari , Jeanine C Pestoni , Paulina Ogar , Ilias Angelidis , Andreas Liontos , José Alberto Rodriguez-Castillo , Niklas J Lang , Maximilian Strunz , Diana Porras-Gonzalez , Michael Gerckens , Laurens J De Sadeleer , Bettina Oehrle , Valeria Viteri-Alvarez , Isis E Fernandez , Michelle Tallquist , Martin Irmler , Johannes Beckers , Oliver Eickelberg , Gabriel Mircea Stoleriu , Jürgen Behr , Nikolaus Kneidinger , Wim A Wuyts , Roxana Maria Wasnick , Ali Önder Yildirim , Katrin Ahlbrecht , Rory E Morty , Christos Samakovlis , Fabian J Theis , Gerald Burgstaller , Herbert B Schiller

GLI1+ Cells Contribute to Vascular Remodeling in Pulmonary Hypertension.

Circulation research

Avec: Xuran Chu , Vahid Kheirollahi , Arun Lingampally , Prakash Chelladurai , Chanil Valasarajan , Ana Ivonne Vazquez-Armendariz , Stefan Hadzic , Ali Khadim , Oleg Pak , Stefano Rivetti , Jochen Wilhelm , Marek Bartkuhn , Slaven Crnkovic , Alena Moiseenko , Monika Heiner , Simone Kraut , Leila Sotoodeh , Janine Koepke , Guilherme Valente , Clemens Ruppert , Thomas Braun , Christos Samakovlis , Ioannis Alexopoulos , Mario Looso , Cho-Ming Chao , Susanne Herold , Werner Seeger , Grazyna Kwapiszewska , Xiaoying Huang , Jin-San Zhang , Soni Savai Pullamsetti , Norbert Weissmann , Xiaokun Li , Elie El Agha , Saverio Bellusci

High-parametric protein maps reveal the spatial organization in early-developing human lung.

Nature communications

Avec: Sanem Sariyar , Alexandros Sountoulidis , Jan Niklas Hansen , Sergio Marco Salas , Mariya Mardamshina , Anna Martinez Casals , Frederic Ballllosera Navarro , Zaneta Andrusivova , Xiaofei Li , Paulo Czarnewski , Joakim Lundeberg , Sten Linnarsson , Mats Nilsson , Erik Sundström , Christos Samakovlis , Emma Lundberg , Burcu Ayoglu

Yorkie controls tube length and apical barrier integrity during airway development.

The Journal of cell biology

Avec: Kassiani Skouloudaki , Ioannis Christodoulou , Dilan Khalili , Vasilios Tsarouhas , Christos Samakovlis , Pavel Tomancak , Elisabeth Knust , Dimitrios K Papadopoulos

WASH phosphorylation balances endosomal versus cortical actin network integrities during epithelial morphogenesis.

Nature communications

Avec: Vasilios Tsarouhas , Dan Liu , Georgia Tsikala , Alina Fedoseienko , Kai Zinn , Ryo Matsuda , Daniel D Billadeau , Christos Samakovlis

SCRINSHOT enables spatial mapping of cell states in tissue sections with single-cell resolution.

PLoS biology

Avec: Alexandros Sountoulidis , Andreas Liontos , Hong Phuong Nguyen , Alexandra B Firsova , Athanasios Fysikopoulos , Xiaoyan Qian , Werner Seeger , Erik Sundström , Mats Nilsson , Christos Samakovlis

Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples.

Nature communications

Avec: Reza Mirzazadeh , Zaneta Andrusivova , Ludvig Larsson , Phillip T Newton , Leire Alonso Galicia , Xesús M Abalo , Mahtab Avijgan , Linda Kvastad , Alexandre Denadai-Souza , Nathalie Stakenborg , Alexandra B Firsova , Alia Shamikh , Aleksandra Jurek , Niklas Schultz , Monica Nistér , Christos Samakovlis , Guy Boeckxstaens , Joakim Lundeberg

Clathrin-Mediated Albumin Clearance in Alveolar Epithelial Cells of Murine Precision-Cut Lung Slices.

International journal of molecular sciences

Avec: Vitalii Kryvenko , Andrés Alberro-Brage , Athanasios Fysikopoulos , Miriam Wessendorf , Khodr Tello , Rory E Morty , Susanne Herold , Werner Seeger , Christos Samakovlis , István Vadász

Dietary nitrite extends lifespan and prevents age-related locomotor decline in the fruit fly.

Free radical biology & medicine

Avec: Chiara H Moretti , Tomas A Schiffer , Marcelo F Montenegro , Filip J Larsen , Vasilios Tsarouhas , Mattias Carlström , Christos Samakovlis , Eddie Weitzberg , Jon O Lundberg

Influenza virus decreases albumin uptake and megalin expression in alveolar epithelial cells.

Frontiers in immunology

Avec: Andrés Alberro-Brage , Vitalii Kryvenko , Christina Malainou , Stefan Günther , Rory E Morty , Werner Seeger , Susanne Herold , Christos Samakovlis , István Vadász

Scavenger receptor endocytosis controls apical membrane morphogenesis in the

eLife

Avec: Ana Sofia Pinheiro , Vasilios Tsarouhas , Kirsten André Senti , Badrul Arefin , Christos Samakovlis

A topographic atlas defines developmental origins of cell heterogeneity in the human embryonic lung.

Nature cell biology

Avec: Alexandros Sountoulidis , Sergio Marco Salas , Emelie Braun , Christophe Avenel , Joseph Bergenstråhle , Jonas Theelke , Marco Vicari , Paulo Czarnewski , Andreas Liontos , Xesus Abalo , Žaneta Andrusivová , Reza Mirzazadeh , Michaela Asp , Xiaofei Li , Lijuan Hu , Sanem Sariyar , Anna Martinez Casals , Burcu Ayoglu , Alexandra Firsova , Jakob Michaëlsson , Emma Lundberg , Carolina Wählby , Erik Sundström , Sten Linnarsson , Joakim Lundeberg , Mats Nilsson , Christos Samakovlis

Evidence for a lipofibroblast-to-

The European respiratory journal

Avec: Arun Lingampally , Marin Truchi , Olivier Mauduit , Vanessa Delcroix , Esmeralda Vasquez-Pacheco , Marine Gautier-Isola , Xuran Chu , Ali Khadim , Cho-Ming Chao , Mahsa Zabihi , Sara Taghizadeh , Stefano Rivetti , Manuela Marega , Alena Moiseenko , Stefan Hadzic , Ana Ivonne Vazquez-Armendariz , Susanne Herold , Stefan Günther , Pamela Millar-Büchner , Janine Koepke , Christos Samakovlis , Jochen Wilhelm , Marek Bartkuhn , Thomas Braun , Norbert Weissmann , JinSan Zhang , Malgorzata Wygrecka , Helen P Makarenkova , Andreas Günther , Werner Seeger , Chengshui Chen , Elie El Agha , Bernard Mari , Saverio Bellusci

Réseau de co-auteurs

Werner Seeger 9 collaborations

Susanne Herold 7 collaborations

Vasilios Tsarouhas 6 collaborations

Janine Koepke 6 collaborations

Ana Ivonne Vazquez-Armendariz 5 collaborations

Saverio Bellusci 5 collaborations

Alexandros Sountoulidis 5 collaborations

Arun Lingampally 4 collaborations

Jochen Wilhelm 4 collaborations

Andreas Liontos 4 collaborations

Joakim Lundeberg 4 collaborations

Mats Nilsson 4 collaborations

Norbert Weissmann 4 collaborations

Stefano Rivetti 4 collaborations

Dan Liu 3 collaborations

Xuran Chu 3 collaborations

Alena Moiseenko 3 collaborations

Ali Khadim 3 collaborations

Stefan Günther 3 collaborations

Andreas Günther 3 collaborations

Thomas Braun 3 collaborations

Jin-San Zhang 3 collaborations

Elie El Agha 3 collaborations

Clemens Ruppert 3 collaborations

Athanasios Fysikopoulos 3 collaborations

Alexandra B Firsova 3 collaborations

Cho-Ming Chao 3 collaborations

Rory E Morty 3 collaborations

Erik Sundström 3 collaborations

Vahid Kheirollahi 2 collaborations

Mahsa Zabihi 2 collaborations

Irina Shalashova 2 collaborations

Ioannis Alexopoulos 2 collaborations

Marin Truchi 2 collaborations

Bernard Mari 2 collaborations

Xiaokun Li 2 collaborations

Christoph H Mayr 2 collaborations

Xesús M Abalo 2 collaborations

Ludvig Larsson 2 collaborations

Herbert B Schiller 2 collaborations

Fabian J Theis 2 collaborations

Sara Taghizadeh 2 collaborations

Simone Kraut 2 collaborations

Monika Heiner 2 collaborations

Georgia Tsikala 2 collaborations

Chanil Valasarajan 2 collaborations

Stefan Hadzic 2 collaborations

Marek Bartkuhn 2 collaborations

Sanem Sariyar 2 collaborations

Sergio Marco Salas 2 collaborations

Anna Martinez Casals 2 collaborations

Zaneta Andrusivova 2 collaborations

Xiaofei Li 2 collaborations

Paulo Czarnewski 2 collaborations

Sten Linnarsson 2 collaborations

Emma Lundberg 2 collaborations

Burcu Ayoglu 2 collaborations

Reza Mirzazadeh 2 collaborations

Vitalii Kryvenko 2 collaborations

Andrés Alberro-Brage 2 collaborations

István Vadász 2 collaborations

Georgios Kiliaris 1 collaboration

Mahtab Shahriari Felordi 1 collaboration

Kevin Lebrigand 1 collaboration

Oleksiy Klymenko 1 collaboration

Martin Huehn 1 collaboration

Roxana Wasnick 1 collaboration

Ingrid Henneke 1 collaboration

Stefanie Hezel 1 collaboration

Katharina Guenther 1 collaboration

Poornima Mahavadi 1 collaboration

Andreas Guenther 1 collaboration

Martina Korfei 1 collaboration

Wenguang Yin 1 collaboration

Maroua Ghoul 1 collaboration

Luciana Mazzocchi 1 collaboration

Xinyuan Liu 1 collaboration

Chunyan Lu 1 collaboration

Haoyu Wu 1 collaboration

Didier Y R Stainier 1 collaboration

Malte D Luecken 1 collaboration

Laure-Emmanuelle Zaragosi 1 collaboration

Elo Madissoon 1 collaboration

Lisa Sikkema 1 collaboration

Elena De Domenico 1 collaboration

Louis Kümmerle 1 collaboration

Adem Saglam 1 collaboration

Marijn Berg 1 collaboration

Aurore C A Gay 1 collaboration

Janine Schniering 1 collaboration

Sarah A Teichmann 1 collaboration

Karen van Eunen 1 collaboration

Gerard H Koppelman 1 collaboration

Kourosh Saeb-Parsy 1 collaboration

Sylvie Leroy 1 collaboration

Pippa Powell 1 collaboration

Ugis Sarkans 1 collaboration

Wim Timens 1 collaboration

Maarten van den Berge 1 collaboration

Peter Horváth 1 collaboration

Jessica Denning 1 collaboration

Irene Papatheodorou 1 collaboration

Joachim L Schultze 1 collaboration

Pascal Barbry 1 collaboration

Ilya Petoukhov 1 collaboration

Alexander V Misharin 1 collaboration

Ian M Adcock 1 collaboration

Michael von Papen 1 collaboration

Kerstin B Meyer 1 collaboration

Martijn C Nawijn 1 collaboration

Stefan Guenther 1 collaboration

Lea Glaser 1 collaboration

Luisa Gersmann 1 collaboration

Gabriela Michel 1 collaboration

Kerstin Goth 1 collaboration

Francesca Ricci 1 collaboration

Giorgio Aquila 1 collaboration

Laurent Boyer 1 collaboration

Harald Ehrhardt 1 collaboration

Parviz Minoo 1 collaboration

Ylva Engström 1 collaboration

Maura Strigini 1 collaboration

Swati Dabral 1 collaboration

Christian Muecke 1 collaboration

Mario Schmoranzer 1 collaboration

Astrid Wietelmann 1 collaboration

Gregg L Semenza 1 collaboration

Michael Meister 1 collaboration

Thomas Muley 1 collaboration

Tamina Seeger-Nukpezah 1 collaboration

Friedrich Grimminger 1 collaboration

Rajkumar Savai 1 collaboration

Soni S Pullamsetti 1 collaboration

Negah Ahmadvand 1 collaboration

Farhad Khosravi 1 collaboration

Matthew R Jones 1 collaboration

Guillermo Barreto 1 collaboration

Gianni Carraro 1 collaboration

Denise Al Alam 1 collaboration

Arunima Sengupta 1 collaboration

Sara Asgharpour 1 collaboration

Meshal Ansari 1 collaboration

Jeanine C Pestoni 1 collaboration

Paulina Ogar 1 collaboration

Ilias Angelidis 1 collaboration

José Alberto Rodriguez-Castillo 1 collaboration

Niklas J Lang 1 collaboration

Maximilian Strunz 1 collaboration

Diana Porras-Gonzalez 1 collaboration

Michael Gerckens 1 collaboration

Laurens J De Sadeleer 1 collaboration

Bettina Oehrle 1 collaboration

Valeria Viteri-Alvarez 1 collaboration

Isis E Fernandez 1 collaboration

Michelle Tallquist 1 collaboration

Martin Irmler 1 collaboration

Johannes Beckers 1 collaboration

Oliver Eickelberg 1 collaboration

Gabriel Mircea Stoleriu 1 collaboration

Jürgen Behr 1 collaboration

Nikolaus Kneidinger 1 collaboration

Wim A Wuyts 1 collaboration

Roxana Maria Wasnick 1 collaboration

Ali Önder Yildirim 1 collaboration

Katrin Ahlbrecht 1 collaboration

Gerald Burgstaller 1 collaboration

Prakash Chelladurai 1 collaboration

Oleg Pak 1 collaboration

Slaven Crnkovic 1 collaboration

Leila Sotoodeh 1 collaboration

Guilherme Valente 1 collaboration

Mario Looso 1 collaboration

Grazyna Kwapiszewska 1 collaboration

Xiaoying Huang 1 collaboration

Soni Savai Pullamsetti 1 collaboration

Jan Niklas Hansen 1 collaboration

Mariya Mardamshina 1 collaboration

Frederic Ballllosera Navarro 1 collaboration

Kassiani Skouloudaki 1 collaboration

Ioannis Christodoulou 1 collaboration

Dilan Khalili 1 collaboration

Pavel Tomancak 1 collaboration

Elisabeth Knust 1 collaboration

Dimitrios K Papadopoulos 1 collaboration

Alina Fedoseienko 1 collaboration

Kai Zinn 1 collaboration

Ryo Matsuda 1 collaboration

Daniel D Billadeau 1 collaboration

Hong Phuong Nguyen 1 collaboration

Xiaoyan Qian 1 collaboration

Phillip T Newton 1 collaboration

Leire Alonso Galicia 1 collaboration

Mahtab Avijgan 1 collaboration

Linda Kvastad 1 collaboration

Alexandre Denadai-Souza 1 collaboration

Nathalie Stakenborg 1 collaboration

Alia Shamikh 1 collaboration

Aleksandra Jurek 1 collaboration

Niklas Schultz 1 collaboration

Monica Nistér 1 collaboration

Guy Boeckxstaens 1 collaboration

Miriam Wessendorf 1 collaboration

Khodr Tello 1 collaboration

Chiara H Moretti 1 collaboration

Tomas A Schiffer 1 collaboration

Marcelo F Montenegro 1 collaboration

Filip J Larsen 1 collaboration

Mattias Carlström 1 collaboration

Eddie Weitzberg 1 collaboration

Jon O Lundberg 1 collaboration

Christina Malainou 1 collaboration

Ana Sofia Pinheiro 1 collaboration

Kirsten André Senti 1 collaboration

Badrul Arefin 1 collaboration

Emelie Braun 1 collaboration

Christophe Avenel 1 collaboration

Joseph Bergenstråhle 1 collaboration

Jonas Theelke 1 collaboration

Marco Vicari 1 collaboration

Xesus Abalo 1 collaboration

Žaneta Andrusivová 1 collaboration

Michaela Asp 1 collaboration

Lijuan Hu 1 collaboration

Alexandra Firsova 1 collaboration

Jakob Michaëlsson 1 collaboration

Carolina Wählby 1 collaboration

Olivier Mauduit 1 collaboration

Vanessa Delcroix 1 collaboration

Esmeralda Vasquez-Pacheco 1 collaboration

Marine Gautier-Isola 1 collaboration

Manuela Marega 1 collaboration

Pamela Millar-Büchner 1 collaboration

JinSan Zhang 1 collaboration

Malgorzata Wygrecka 1 collaboration

Helen P Makarenkova 1 collaboration

Chengshui Chen 1 collaboration