E Crespan

Affiliations

Faculty of Sciences, Institute of Molecular Genetics "Luigi Luca Cavalli-Sforza" IGM-CNR , Pavia , Italy.

Publications (21)

Towards Innovative Antibacterial Correctors for Cystic Fibrosis Targeting the Lung Microbiome with a Multifunctional Effect.

ChemMedChem

Avec: Maria Grazia Martina , Filomena Sannio , Emmanuele Crespan , Marialaura Pavone , Alice Simoncini , Francesca Barbieri , Cecilia Perini , Emanuela Pesce , Giovanni Maga , Nicoletta Pedemonte , Jean-Denis Docquier , Marco Radi

Novel pyrazolo[3,4-d]pyrimidines as dual Src/Bcr-Abl kinase inhibitors: Synthesis and biological evaluation for chronic myeloid leukemia treatment.

Bioorganic chemistry

Avec: Salvatore Di Maria , Francesca Picarazzi , Mattia Mori , Annarita Cianciusi , Anna Carbone , Emmanuele Crespan , Cecilia Perini , Samantha Sabetta , Serenella Deplano , Federica Poggialini , Alessio Molinari , Rossella Aronne , Elias Maccioni , Giovanni Maga , Adriano Angelucci , Silvia Schenone , Francesca Musumeci , Elena Dreassi

Identification and Biological Characterization of the Pyrazolo[3,4-

Pharmaceuticals (Basel, Switzerland)

Avec: Claudia Contadini , Claudia Cirotti , Anna Carbone , Mehrdad Norouzi , Annarita Cianciusi , Emmanuele Crespan , Cecilia Perini , Giovanni Maga , Daniela Barilà , Francesca Musumeci , Silvia Schenone

A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres.

International journal of molecular sciences

Avec: Elisa Mentegari , Federica Bertoletti , Miroslava Kissova , Elisa Zucca , Silvia Galli , Giulia Tagliavini , Anna Garbelli , Antonio Maffia , Silvia Bione , Elena Ferrari , Fabrizio d'Adda di Fagagna , Sofia Francia , Simone Sabbioneda , Liuh-Yow Chen , Joachim Lingner , Valerie Bergoglio , Jean-Sébastien Hoffmann , Ulrich Hübscher , Emmanuele Crespan , Giovanni Maga

Molecular docking, design, synthesis and biological evaluation of novel 2,3-aryl-thiazolidin-4-ones as potent NNRTIs.

SAR and QSAR in environmental research

Avec: A Geronikaki , A Petrou , V Kartsev , P Eleftheriou , R Boga , B Bartolo , E Crespan , G Franco , G Maga

New indolylarylsulfone non-nucleoside reverse transcriptase inhibitors show low nanomolar inhibition of single and double HIV-1 mutant strains.

European journal of medicinal chemistry

Avec: Marianna Nalli , Jorge I Armijos Rivera , Domiziana Masci , Antonio Coluccia , Roger Badia , Eva Riveira-Muñoz , Alessandro Brambilla , Elisabetta Cinquina , Ombretta Turriziani , Francesca Falasca , Myriam Catalano , Cristina Limatola , José A Esté , Giovanni Maga , Romano Silvestri , Emmanuele Crespan , Giuseppe La Regina

High Flexibility of RNaseH2 Catalytic Activity with Respect to Non-Canonical DNA Structures.

International journal of molecular sciences

Avec: Maria Dede , Silvia Napolitano , Anna Melati , Valentina Pirota , Giovanni Maga , Emmanuele Crespan

Truncating Variants in

Neurology

Avec: Riccardo Ronco , Cecilia Perini , Riccardo Currò , Natalia Dominik , Stefano Facchini , Alice Gennari , Roberto Simone , Skye Stuart , Sara Nagy , Elisa Vegezzi , Ilaria Quartesan , Amar El-Saddig , Timothy Lavin , Arianna Tucci , Agnieszka Szymura , Luiz Eduardo Novis De Farias , Alexander Gary , Megan Delfeld , Priscilla Kandikatla , Nifang Niu , Sanjukta Tawde , Joseph Shaw , James Polke , Mary M Reilly , Nick W Wood , Emmanuele Crespan , Christopher Gomez , Jin Yun Helen Chen , Jeremy Dan Schmahmann , David Gosal , Henry Houlden , Soma Das , Andrea Cortese

Normal and pathogenic variation of RFC1 repeat expansions: implications for clinical diagnosis.

Brain : a journal of neurology

Avec: Natalia Dominik , Stefania Magri , Riccardo Currò , Elena Abati , Stefano Facchini , Marinella Corbetta , Hannah Macpherson , Daniela Di Bella , Elisa Sarto , Igor Stevanovski , Sanjog R Chintalaphani , Fulya Akcimen , Arianna Manini , Elisa Vegezzi , Ilaria Quartesan , Kylie-Ann Montgomery , Valentina Pirota , Emmanuele Crespan , Cecilia Perini , Glenda Paola Grupelli , Pedro J Tomaselli , Wilson Marques , Auteur inconnu , Joseph Shaw , James Polke , Ettore Salsano , Silvia Fenu , Davide Pareyson , Chiara Pisciotta , George K Tofaris , Andrea H Nemeth , John Ealing , Aleksandar Radunovic , Seamus Kearney , Kishore R Kumar , Steve Vucic , Marina Kennerson , Mary M Reilly , Henry Houlden , Ira Deveson , Arianna Tucci , Franco Taroni , Andrea Cortese

Multitarget CFTR Modulators Endowed with Multiple Beneficial Side Effects for Cystic Fibrosis Patients: Toward a Simplified Therapeutic Approach †.

Journal of medicinal chemistry

Avec: Sabrina Tassini , Emily Langron , Leen Delang , Carmen Mirabelli , Kristina Lanko , Emmanuele Crespan , Miroslava Kissova , Giulia Tagliavini , Greta Fontò , Simona Bertoni , Simone Palese , Carmine Giorgio , Francesca Ravanetti , Luisa Ragionieri , Claudio Zamperini , Arianna Mancini , Elena Dreassi , Giovanni Maga , Paola Vergani , Johan Neyts , Marco Radi

Bithiazole Inhibitors of Phosphatidylinositol 4-Kinase (PI4KIIIβ) as Broad-Spectrum Antivirals Blocking the Replication of SARS-CoV-2, Zika Virus, and Human Rhinoviruses.

ChemMedChem

Avec: Maria Grazia Martina , Ilaria Vicenti , Lisa Bauer , Emmanuele Crespan , Enrico Rango , Adele Boccuto , Noemi Olivieri , Matteo Incerti , Marleen Zwaagstra , Marika Allodi , Simona Bertoni , Elena Dreassi , Maurizio Zazzi , Frank J M van Kuppeveld , Giovanni Maga , Marco Radi

Synthesis and biological activity evaluation of 3-(hetero) arylideneindolin-2-ones as potential c-Src inhibitors.

Journal of enzyme inhibition and medicinal chemistry

Avec: Salvatore Princiotto , Loana Musso , Fabrizio Manetti , Valentina Marcellini , Giovanni Maga , Emmanuele Crespan , Cecilia Perini , Nadia Zaffaroni , Giovanni Luca Beretta , Sabrina Dallavalle

Bithiazole inhibitors of PI4KB show broad-spectrum antiviral activity against different viral families.

Antiviral research

Avec: Maria Grazia Martina , Vincent Carlen , Sarah Van der Reysen , Elena Bianchi , Noemi Cabella , Emmanuele Crespan , Marco Radi , Valeria Cagno

System-oriented optimization of multi-target 2,6-diaminopurine derivatives: Easily accessible broad-spectrum antivirals active against flaviviruses, influenza virus and SARS-CoV-2.

European journal of medicinal chemistry

Avec: Ilaria Vicenti , Maria Grazia Martina , Adele Boccuto , Marta De Angelis , Giorgia Giavarini , Filippo Dragoni , Serena Marchi , Claudia Maria Trombetta , Emmanuele Crespan , Giovanni Maga , Cecilia Eydoux , Etienne Decroly , Emanuele Montomoli , Lucia Nencioni , Maurizio Zazzi , Marco Radi

Biological Evaluation and In Vitro Characterization of ADME Profile of In-House Pyrazolo[3,4-

Pharmaceutics

Avec: Federica Poggialini , Chiara Vagaggini , Annalaura Brai , Claudia Pasqualini , Emmanuele Crespan , Giovanni Maga , Cecilia Perini , Noemi Cabella , Lorenzo Botta , Francesca Musumeci , Maria Frosini , Silvia Schenone , Elena Dreassi

Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines.

European journal of medicinal chemistry

Avec: Anna Lucia Fallacara , Raffaele Passannanti , Mattia Mori , Giulia Iovenitti , Francesca Musumeci , Chiara Greco , Emmanuele Crespan , Miroslava Kissova , Giovanni Maga , Chiara Tarantelli , Filippo Spriano , Eugenio Gaudio , Francesco Bertoni , Maurizio Botta , Silvia Schenone

Effect of α-Methoxy Substitution on the Anti-HIV Activity of Dihydropyrimidin-4(3 H)-ones.

Journal of medicinal chemistry

Avec: Maxim B Nawrozkij , Mariantonietta Forgione , Alexandre S Yablokov , Alessia Lucidi , Daniela Tomaselli , Alexandros Patsilinakos , Cristina Panella , Gebremedhin S Hailu , Ivan A Kirillov , Roger Badia , Eva Riveira-Muñoz , Emmanuele Crespan , Jorge I Armijos Rivera , Roberto Cirilli , Rino Ragno , José A Esté , Giovanni Maga , Antonello Mai , Dante Rotili

Selective Binding and Redox-Activity on Parallel G-Quadruplexes by Pegylated Naphthalene Diimide-Copper Complexes.

Molecules (Basel, Switzerland)

Avec: Valentina Pirota , Enrico Lunghi , Alessandra Benassi , Emmanuele Crespan , Mauro Freccero , Filippo Doria

Synergistic action of human RNaseH2 and the RNA helicase-nuclease DDX3X in processing R-loops.

Nucleic acids research

Avec: Massimiliano Secchi , Anna Garbelli , Valentina Riva , Graziano Deidda , Carolina Santonicola , Teresa Maria Formica , Simone Sabbioneda , Emmanuele Crespan , Giovanni Maga

4-Trifluoromethyl bithiazoles as broad-spectrum antimicrobial agents for virus-related bacterial infections or co-infections.

RSC medicinal chemistry

Avec: Francesca Barbieri , Vincent Carlen , Maria Grazia Martina , Filomena Sannio , Sacha Cancade , Cecilia Perini , Margherita Restori , Emmanuele Crespan , Giovanni Maga , Jean-Denis Docquier , Valeria Cagno , Marco Radi

Applying molecular hybridization to design a new class of pyrazolo[3,4-d]pyrimidines as Src inhibitors active in hepatocellular carcinoma.

European journal of medicinal chemistry

Avec: Salvatore Di Maria , Raffaele Passannanti , Federica Poggialini , Chiara Vagaggini , Alessia Serafinelli , Elena Bianchi , Paolo Governa , Lorenzo Botta , Giovanni Maga , Emmanuele Crespan , Fabrizio Manetti , Elena Dreassi , Francesca Musumeci , Anna Carbone , Silvia Schenone

Réseau de co-auteurs

Emmanuele Crespan 20 collaborations

Giovanni Maga 16 collaborations

Cecilia Perini 8 collaborations

Marco Radi 6 collaborations

Maria Grazia Martina 5 collaborations

Silvia Schenone 5 collaborations

Francesca Musumeci 5 collaborations

Elena Dreassi 5 collaborations

Anna Carbone 3 collaborations

Federica Poggialini 3 collaborations

Miroslava Kissova 3 collaborations

Valentina Pirota 3 collaborations

Filomena Sannio 2 collaborations

Francesca Barbieri 2 collaborations

Jean-Denis Docquier 2 collaborations

Salvatore Di Maria 2 collaborations

Mattia Mori 2 collaborations

Annarita Cianciusi 2 collaborations

Giulia Tagliavini 2 collaborations

Anna Garbelli 2 collaborations

Simone Sabbioneda 2 collaborations

Jorge I Armijos Rivera 2 collaborations

Roger Badia 2 collaborations

Eva Riveira-Muñoz 2 collaborations

José A Esté 2 collaborations

Riccardo Currò 2 collaborations

Natalia Dominik 2 collaborations

Stefano Facchini 2 collaborations

Elisa Vegezzi 2 collaborations

Ilaria Quartesan 2 collaborations

Arianna Tucci 2 collaborations

Joseph Shaw 2 collaborations

James Polke 2 collaborations

Mary M Reilly 2 collaborations

Henry Houlden 2 collaborations

Andrea Cortese 2 collaborations

Simona Bertoni 2 collaborations

Ilaria Vicenti 2 collaborations

Adele Boccuto 2 collaborations

Maurizio Zazzi 2 collaborations

Fabrizio Manetti 2 collaborations

Vincent Carlen 2 collaborations

Elena Bianchi 2 collaborations

Noemi Cabella 2 collaborations

Valeria Cagno 2 collaborations

Chiara Vagaggini 2 collaborations

Lorenzo Botta 2 collaborations

Raffaele Passannanti 2 collaborations

Marialaura Pavone 1 collaboration

Alice Simoncini 1 collaboration

Emanuela Pesce 1 collaboration

Nicoletta Pedemonte 1 collaboration

Francesca Picarazzi 1 collaboration

Samantha Sabetta 1 collaboration

Serenella Deplano 1 collaboration

Alessio Molinari 1 collaboration

Rossella Aronne 1 collaboration

Elias Maccioni 1 collaboration

Adriano Angelucci 1 collaboration

Claudia Contadini 1 collaboration

Claudia Cirotti 1 collaboration

Mehrdad Norouzi 1 collaboration

Daniela Barilà 1 collaboration

Elisa Mentegari 1 collaboration

Federica Bertoletti 1 collaboration

Elisa Zucca 1 collaboration

Silvia Galli 1 collaboration

Antonio Maffia 1 collaboration

Silvia Bione 1 collaboration

Elena Ferrari 1 collaboration

Fabrizio d'Adda di Fagagna 1 collaboration

Sofia Francia 1 collaboration

Liuh-Yow Chen 1 collaboration

Joachim Lingner 1 collaboration

Valerie Bergoglio 1 collaboration

Jean-Sébastien Hoffmann 1 collaboration

Ulrich Hübscher 1 collaboration

A Geronikaki 1 collaboration

A Petrou 1 collaboration

V Kartsev 1 collaboration

P Eleftheriou 1 collaboration

R Boga 1 collaboration

B Bartolo 1 collaboration

G Franco 1 collaboration

G Maga 1 collaboration

Marianna Nalli 1 collaboration

Domiziana Masci 1 collaboration

Antonio Coluccia 1 collaboration

Alessandro Brambilla 1 collaboration

Elisabetta Cinquina 1 collaboration

Ombretta Turriziani 1 collaboration

Francesca Falasca 1 collaboration

Myriam Catalano 1 collaboration

Cristina Limatola 1 collaboration

Romano Silvestri 1 collaboration

Giuseppe La Regina 1 collaboration

Maria Dede 1 collaboration

Silvia Napolitano 1 collaboration

Anna Melati 1 collaboration

Riccardo Ronco 1 collaboration

Alice Gennari 1 collaboration

Roberto Simone 1 collaboration

Skye Stuart 1 collaboration

Sara Nagy 1 collaboration

Amar El-Saddig 1 collaboration

Timothy Lavin 1 collaboration

Agnieszka Szymura 1 collaboration

Luiz Eduardo Novis De Farias 1 collaboration

Alexander Gary 1 collaboration

Megan Delfeld 1 collaboration

Priscilla Kandikatla 1 collaboration

Nifang Niu 1 collaboration

Sanjukta Tawde 1 collaboration

Nick W Wood 1 collaboration

Christopher Gomez 1 collaboration

Jin Yun Helen Chen 1 collaboration

Jeremy Dan Schmahmann 1 collaboration

David Gosal 1 collaboration

Soma Das 1 collaboration

Stefania Magri 1 collaboration

Elena Abati 1 collaboration

Marinella Corbetta 1 collaboration

Hannah Macpherson 1 collaboration

Daniela Di Bella 1 collaboration

Elisa Sarto 1 collaboration

Igor Stevanovski 1 collaboration

Sanjog R Chintalaphani 1 collaboration

Fulya Akcimen 1 collaboration

Arianna Manini 1 collaboration

Kylie-Ann Montgomery 1 collaboration

Glenda Paola Grupelli 1 collaboration

Pedro J Tomaselli 1 collaboration

Wilson Marques 1 collaboration

None None 1 collaboration

Ettore Salsano 1 collaboration

Silvia Fenu 1 collaboration

Davide Pareyson 1 collaboration

Chiara Pisciotta 1 collaboration

George K Tofaris 1 collaboration

Andrea H Nemeth 1 collaboration

John Ealing 1 collaboration

Aleksandar Radunovic 1 collaboration

Seamus Kearney 1 collaboration

Kishore R Kumar 1 collaboration

Steve Vucic 1 collaboration

Marina Kennerson 1 collaboration

Ira Deveson 1 collaboration

Franco Taroni 1 collaboration

Sabrina Tassini 1 collaboration

Emily Langron 1 collaboration

Leen Delang 1 collaboration

Carmen Mirabelli 1 collaboration

Kristina Lanko 1 collaboration

Greta Fontò 1 collaboration

Simone Palese 1 collaboration

Carmine Giorgio 1 collaboration

Francesca Ravanetti 1 collaboration

Luisa Ragionieri 1 collaboration

Claudio Zamperini 1 collaboration

Arianna Mancini 1 collaboration

Paola Vergani 1 collaboration

Johan Neyts 1 collaboration

Lisa Bauer 1 collaboration

Enrico Rango 1 collaboration

Noemi Olivieri 1 collaboration

Matteo Incerti 1 collaboration

Marleen Zwaagstra 1 collaboration

Marika Allodi 1 collaboration

Frank J M van Kuppeveld 1 collaboration

Salvatore Princiotto 1 collaboration

Loana Musso 1 collaboration

Valentina Marcellini 1 collaboration

Nadia Zaffaroni 1 collaboration

Giovanni Luca Beretta 1 collaboration

Sabrina Dallavalle 1 collaboration

Sarah Van der Reysen 1 collaboration

Marta De Angelis 1 collaboration

Giorgia Giavarini 1 collaboration

Filippo Dragoni 1 collaboration

Serena Marchi 1 collaboration

Claudia Maria Trombetta 1 collaboration

Cecilia Eydoux 1 collaboration

Etienne Decroly 1 collaboration

Emanuele Montomoli 1 collaboration

Lucia Nencioni 1 collaboration

Annalaura Brai 1 collaboration

Claudia Pasqualini 1 collaboration

Maria Frosini 1 collaboration

Anna Lucia Fallacara 1 collaboration

Giulia Iovenitti 1 collaboration

Chiara Greco 1 collaboration

Chiara Tarantelli 1 collaboration

Filippo Spriano 1 collaboration

Eugenio Gaudio 1 collaboration

Francesco Bertoni 1 collaboration

Maurizio Botta 1 collaboration

Maxim B Nawrozkij 1 collaboration

Mariantonietta Forgione 1 collaboration

Alexandre S Yablokov 1 collaboration

Alessia Lucidi 1 collaboration

Daniela Tomaselli 1 collaboration

Alexandros Patsilinakos 1 collaboration

Cristina Panella 1 collaboration

Gebremedhin S Hailu 1 collaboration

Ivan A Kirillov 1 collaboration

Roberto Cirilli 1 collaboration

Rino Ragno 1 collaboration

Antonello Mai 1 collaboration

Dante Rotili 1 collaboration

Enrico Lunghi 1 collaboration

Alessandra Benassi 1 collaboration

Mauro Freccero 1 collaboration

Filippo Doria 1 collaboration

Massimiliano Secchi 1 collaboration

Valentina Riva 1 collaboration

Graziano Deidda 1 collaboration

Carolina Santonicola 1 collaboration

Teresa Maria Formica 1 collaboration

Sacha Cancade 1 collaboration

Margherita Restori 1 collaboration

Alessia Serafinelli 1 collaboration

Paolo Governa 1 collaboration