Eric T Kool

Affiliations

Department of Chemistry, Stanford Cancer Institute, and Chemistry, Engineering and Medicine for Human Health Institute, Stanford University, Stanford, CA 94305 kool@stanford.edu xzw10484@rjh.com.cn min.wu@med.und.edu.

ORCID: 0000-0002-7310-2935

Publications (12)

Small-Molecule Inhibitor of 8-Oxoguanine DNA Glycosylase 1 Regulates Inflammatory Responses during

Journal of immunology (Baltimore, Md. : 1950)

Avec: Shugang Qin , Ping Lin , Qun Wu , Qinqin Pu , Chuanmin Zhou , Biao Wang , Pan Gao , Zhihan Wang , Ashley Gao , Madison Overby , Jinliang Yang , Jianxin Jiang , David L Wilson , Yu-Ki Tahara , Eric T Kool , Zhenwei Xia , Min Wu

Designer Fluorescent Adenines Enable Real-Time Monitoring of MUTYH Activity.

ACS central science

Avec: Ru-Yi Zhu , Chandrima Majumdar , Cindy Khuu , Mariarosaria De Rosa , Patricia L Opresko , Sheila S David , Eric T Kool

Inhibition by Tetrahydroquinoline Sulfonamide Derivatives of the Activity of Human 8-Oxoguanine DNA Glycosylase (OGG1) for Several Products of Oxidatively induced DNA Base Lesions.

ACS chemical biology

Avec: Melis Kant , Yu-Ki Tahara , Pawel Jaruga , Erdem Coskun , R Stephen Lloyd , Eric T Kool , Miral Dizdaroglu

OGG1 co-inhibition antagonizes the tumor-inhibitory effects of targeting MTH1.

Redox biology

Avec: Ling Zhang , Laura Misiara , Govindi J Samaranayake , Nisha Sharma , Dao M Nguyen , Yu-Ki Tahara , Eric T Kool , Priyamvada Rai

The chemistry and applications of RNA 2'-OH acylation.

Nature reviews. Chemistry

Avec: Willem A Velema , Eric T Kool

Aqueous Activation of RNA 2'-OH for Conjugation with Amines and Thiols.

Bioconjugate chemistry

Avec: Ryuta Shioi , Lu Xiao , Eric T Kool

Mechanism-Based Strategy for Optimizing HaloTag Protein Labeling.

JACS Au

Avec: Sérgio M Marques , Michaela Slanska , Klaudia Chmelova , Radka Chaloupkova , Martin Marek , Spencer Clark , Jiri Damborsky , Eric T Kool , David Bednar , Zbynek Prokop

Efficient DNA fluorescence labeling via base excision trapping.

Nature communications

Avec: Yong Woong Jun , Emily M Harcourt , Lu Xiao , David L Wilson , Eric T Kool

Diverse Reagent Scaffolds Provide Differential Selectivity of 2'-OH Acylation in RNA.

Journal of the American Chemical Society

Avec: Lu Xiao , Linglan Fang , Sayantan Chatterjee , Eric T Kool

Sulfonylation of RNA 2'-OH groups.

ACS central science

Avec: Sayantan Chatterjee , Ryuta Shioi , Eric T Kool

Reversible RNA Acylation Using Bio-Orthogonal Chemistry Enables Temporal Control of CRISPR-Cas9 Nuclease Activity.

ACS chemical biology

Avec: Bhoomika Pandit , Linglan Fang , Eric T Kool , Maksim Royzen

The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors.

Molecular cancer therapeutics

Avec: Govindi J Samaranayake , Clara I Troccoli , Ling Zhang , Mai Huynh , Christina J Jayaraj , Debin Ji , Lisa McPherson , Yoshiyuki Onishi , Dao M Nguyen , David J Robbins , Mahsa Karbaschi , Marcus S Cooke , Antonio Barrientos , Eric T Kool , Priyamvada Rai

Réseau de co-auteurs

Yu-Ki Tahara 3 collaborations

Lu Xiao 3 collaborations

David L Wilson 2 collaborations

Ling Zhang 2 collaborations

Govindi J Samaranayake 2 collaborations

Dao M Nguyen 2 collaborations

Priyamvada Rai 2 collaborations

Ryuta Shioi 2 collaborations

Linglan Fang 2 collaborations

Sayantan Chatterjee 2 collaborations

Shugang Qin 1 collaboration

Ping Lin 1 collaboration

Qun Wu 1 collaboration

Qinqin Pu 1 collaboration

Chuanmin Zhou 1 collaboration

Biao Wang 1 collaboration

Pan Gao 1 collaboration

Zhihan Wang 1 collaboration

Ashley Gao 1 collaboration

Madison Overby 1 collaboration

Jinliang Yang 1 collaboration

Jianxin Jiang 1 collaboration

Zhenwei Xia 1 collaboration

Min Wu 1 collaboration

Ru-Yi Zhu 1 collaboration

Chandrima Majumdar 1 collaboration

Cindy Khuu 1 collaboration

Mariarosaria De Rosa 1 collaboration

Patricia L Opresko 1 collaboration

Sheila S David 1 collaboration

Melis Kant 1 collaboration

Pawel Jaruga 1 collaboration

Erdem Coskun 1 collaboration

R Stephen Lloyd 1 collaboration

Miral Dizdaroglu 1 collaboration

Laura Misiara 1 collaboration

Nisha Sharma 1 collaboration

Willem A Velema 1 collaboration

Sérgio M Marques 1 collaboration

Michaela Slanska 1 collaboration

Klaudia Chmelova 1 collaboration

Radka Chaloupkova 1 collaboration

Martin Marek 1 collaboration

Spencer Clark 1 collaboration

Jiri Damborsky 1 collaboration

David Bednar 1 collaboration

Zbynek Prokop 1 collaboration

Yong Woong Jun 1 collaboration

Emily M Harcourt 1 collaboration

Bhoomika Pandit 1 collaboration

Maksim Royzen 1 collaboration

Clara I Troccoli 1 collaboration

Mai Huynh 1 collaboration

Christina J Jayaraj 1 collaboration

Debin Ji 1 collaboration

Lisa McPherson 1 collaboration

Yoshiyuki Onishi 1 collaboration

David J Robbins 1 collaboration

Mahsa Karbaschi 1 collaboration

Marcus S Cooke 1 collaboration

Antonio Barrientos 1 collaboration