Gaëtan Chicanne

Affiliations

Institut des Maladies Métaboliques et Cardiovasculaires, Inserm U1048, Université Toulouse III, 31432 Toulouse CEDEX 4, France.

Publications (21)

Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation.

Science translational medicine

Avec: Maria V Selvadurai , Mitchell J Moon , Simon J Mountford , Xiao Ma , Zhaohua Zheng , Ian G Jennings , Natasha M Setiabakti , Rizani P Iman , Rose J Brazilek , Nurul Aisha Z Abidin , Gaëtan Chicanne , Sonia Severin , Alyce J Nicholls , Connie H Y Wong , Jean-Yves Rinckel , Anita Eckly , Christian Gachet , Warwick S Nesbitt , Philip E Thompson , Justin R Hamilton

Exploring the Role of PI3P in Platelets: Insights from a Novel External PI3P Pool.

Biomolecules

Avec: Abdulrahman Mujalli , Julien Viaud , Sonia Severin , Marie-Pierre Gratacap , Gaëtan Chicanne , Karim Hnia , Bernard Payrastre , Anne-Dominique Terrisse

Phosphoinositide 3-kinases in platelets, thrombosis and therapeutics.

The Biochemical journal

Avec: Agnès Ribes , Antoine Oprescu , Julien Viaud , Karim Hnia , Gaëtan Chicanne , Jean-Marie Xuereb , Sonia Severin , Marie-Pierre Gratacap , Bernard Payrastre

C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus.

iScience

Avec: Yu Wu , Nassim Mahtal , Eléa Paillares , Léa Swistak , Sara Sagadiev , Mridu Acharya , Caroline Demeret , Sylvie Van Der Werf , Florence Guivel-Benhassine , Olivier Schwartz , Serena Petracchini , Amel Mettouchi , Lucie Caramelle , Pierre Couvineau , Robert Thai , Peggy Barbe , Mathilde Keck , Priscille Brodin , Arnaud Machelart , Valentin Sencio , François Trottein , Martin Sachse , Gaëtan Chicanne , Bernard Payrastre , Florian Ville , Victor Kreis , Michel-Robert Popoff , Ludger Johannes , Jean-Christophe Cintrat , Julien Barbier , Daniel Gillet , Emmanuel Lemichez

MTM1-mediated production of phosphatidylinositol 5-phosphate fuels the formation of podosome-like protrusions regulating myoblast fusion.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Mélanie Mansat , Afi Oportune Kpotor , Gaëtan Chicanne , Mélanie Picot , Anne Mazars , Rémy Flores-Flores , Bernard Payrastre , Karim Hnia , Julien Viaud

Dysregulation of myelin synthesis and actomyosin function underlies aberrant myelin in CMT4B1 neuropathy.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Marta Guerrero-Valero , Federica Grandi , Silvia Cipriani , Valeria Alberizzi , Roberta Di Guardo , Gaetan Chicanne , Linda Sawade , Francesca Bianchi , Ubaldo Del Carro , Ivan De Curtis , Davide Pareyson , Yesim Parman , Angelo Schenone , Volker Haucke , Bernard Payrastre , Alessandra Bolino

Megakaryocytes form linear podosomes devoid of digestive properties to remodel medullar matrix.

Scientific reports

Avec: Antoine Oprescu , Déborah Michel , Adrien Antkowiak , Elodie Vega , Julien Viaud , Sara A Courtneidge , Anita Eckly , Henri de la Salle , Gaëtan Chicanne , Catherine Léon , Bernard Payrastre , Frédérique Gaits-Iacovoni

What can we learn from the platelet lipidome?

Platelets

Avec: Gaëtan Chicanne , Jean Darcourt , Justine Bertrand-Michel , Cédric Garcia , Agnès Ribes , Bernard Payrastre

Author Correction: Phosphoinositides regulate the TCR/CD3 complex membrane dynamics and activation.

Scientific reports

Avec: Nassima Chouaki Benmansour , Kilian Ruminski , Anne-Marie Sartre , Marie-Claire Phelipot , Audrey Salles , Elise Bergot , Ambroise Wu , Gaëtan Chicanne , Mathieu Fallet , Sophie Brustlein , Cyrille Billaudeau , Anthony Formisano , Sébastien Mailfert , Bernard Payrastre , Didier Marguet , Sophie Brasselet , Yannick Hamon , Hai-Tao He

Profiling of Phosphoinositide Molecular Species in Resting or Activated Human or Mouse Platelets by a LC-MS Method.

Methods in molecular biology (Clifton, N.J.)

Avec: Gaëtan Chicanne , Justine Bertrand-Michel , Julien Viaud , Karim Hnia , Jonathan Clark , Bernard Payrastre

Platelet Lipidome Fingerprint: New Assistance to Characterize Platelet Dysfunction in Obesity.

International journal of molecular sciences

Avec: Gaëtan Chicanne , Maria N Barrachina , Anaelle Durbec , Justine Bertrand-Michel , Sara Troitiño , Lidia Hermida-Nogueira , Aurelio M Sueiro , María Pardo , Bernard Payrastre , Ángel García

Class III PI3K Biology.

Current topics in microbiology and immunology

Avec: Manuella Caux , Gaetan Chicanne , Sonia Severin

Phosphatidylinositol 3 monophosphate metabolizing enzymes in blood platelet production and in thrombosis.

Advances in biological regulation

Avec: Marie Bellio , Manuella Caux , Alicia Vauclard , Gaëtan Chicanne , Marie-Pierre Gratacap , Anne-Dominique Terrisse , Sonia Severin , Bernard Payrastre

PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity.

EMBO reports

Avec: Typhaine Anquetil , Romain Solinhac , Aude Jaffre , Gaëtan Chicanne , Julien Viaud , Jean Darcourt , Cyrille Orset , Eva Geuss , Christoph Kleinschnitz , Bart Vanhaesebroeck , Denis Vivien , Karim Hnia , Vincent Larrue , Bernard Payrastre , Marie-Pierre Gratacap

Liposome-Based Methods to Study Protein-Phosphoinositide Interaction.

Methods in molecular biology (Clifton, N.J.)

Avec: Mélanie Mansat , Mélanie Picot , Gaëtan Chicanne , Virginie Nahoum , Frédérique Gaits-Iacovoni , Bernard Payrastre , Karim Hnia , Julien Viaud

Glycerophosphodiesterase 3 (GDE3) is a lysophosphatidylinositol-specific ectophospholipase C acting as an endocannabinoid signaling switch.

The Journal of biological chemistry

Avec: Fabienne Briand-Mésange , Véronique Pons , Sophie Allart , Julien Masquelier , Gaëtan Chicanne , Nicolas Beton , Bernard Payrastre , Giulio G Muccioli , Jérôme Ausseil , Jean-Luc Davignon , Jean-Pierre Salles , Hugues Chap

PIKfyve-Dependent Phosphoinositide Dynamics in Megakaryocyte/Platelet Granule Integrity and Platelet Functions.

Arteriosclerosis, thrombosis, and vascular biology

Avec: Manuella Caux , Rana Mansour , Jean-Marie Xuereb , Gaëtan Chicanne , Julien Viaud , Alicia Vauclard , Frédéric Boal , Bernard Payrastre , Hélène Tronchère , Sonia Severin

X-linked myotubular myopathy is associated with epigenetic alterations and is ameliorated by HDAC inhibition.

Acta neuropathologica

Avec: Jonathan R Volpatti , Mehdi M Ghahramani-Seno , Mélanie Mansat , Nesrin Sabha , Ege Sarikaya , Sarah J Goodman , Eric Chater-Diehl , Alper Celik , Emanuela Pannia , Carine Froment , Lucie Combes-Soia , Nika Maani , Kyoko E Yuki , Gaëtan Chicanne , Liis Uusküla-Reimand , Simon Monis , Sana Akhtar Alvi , Casie A Genetti , Bernard Payrastre , Alan H Beggs , Carsten G Bonnemann , Francesco Muntoni , Michael D Wilson , Rosanna Weksberg , Julien Viaud , James J Dowling

SHIP1 Controls Internal Platelet Contraction and α

International journal of molecular sciences

Avec: Sonia Severin , Alessandra Consonni , Gaëtan Chicanne , Sophie Allart , Bernard Payrastre , Marie-Pierre Gratacap

Inactivating the lipid kinase activity of PI3KC2β is sufficient to rescue myotubular myopathy in mice.

JCI insight

Avec: Xènia Massana-Muñoz , Marie Goret , Vasugi Nattarayan , David Reiss , Christine Kretz , Gaetan Chicanne , Bernard Payrastre , Bart Vanhaesebroeck , Jocelyn Laporte

Phosphoinositides take a central stage in regulating blood platelet production and function.

Advances in biological regulation

Avec: Sonia Severin , Marie-Pierre Gratacap , Laura Bouvet , Maxime Borret , Afi Oportune Kpotor , Gaëtan Chicanne , Jean-Marie Xuereb , Julien Viaud , Bernard Payrastre

Réseau de co-auteurs

Bernard Payrastre 19 collaborations

Julien Viaud 10 collaborations

Sonia Severin 8 collaborations

Marie-Pierre Gratacap 6 collaborations

Karim Hnia 6 collaborations

Jean-Marie Xuereb 3 collaborations

Mélanie Mansat 3 collaborations

Gaetan Chicanne 3 collaborations

Justine Bertrand-Michel 3 collaborations

Manuella Caux 3 collaborations

Anita Eckly 2 collaborations

Anne-Dominique Terrisse 2 collaborations

Agnès Ribes 2 collaborations

Antoine Oprescu 2 collaborations

Afi Oportune Kpotor 2 collaborations

Mélanie Picot 2 collaborations

Frédérique Gaits-Iacovoni 2 collaborations

Jean Darcourt 2 collaborations

Alicia Vauclard 2 collaborations

Bart Vanhaesebroeck 2 collaborations

Sophie Allart 2 collaborations

Maria V Selvadurai 1 collaboration

Mitchell J Moon 1 collaboration

Simon J Mountford 1 collaboration

Xiao Ma 1 collaboration

Zhaohua Zheng 1 collaboration

Ian G Jennings 1 collaboration

Natasha M Setiabakti 1 collaboration

Rizani P Iman 1 collaboration

Rose J Brazilek 1 collaboration

Nurul Aisha Z Abidin 1 collaboration

Alyce J Nicholls 1 collaboration

Connie H Y Wong 1 collaboration

Jean-Yves Rinckel 1 collaboration

Christian Gachet 1 collaboration

Warwick S Nesbitt 1 collaboration

Philip E Thompson 1 collaboration

Justin R Hamilton 1 collaboration

Abdulrahman Mujalli 1 collaboration

Yu Wu 1 collaboration

Nassim Mahtal 1 collaboration

Eléa Paillares 1 collaboration

Léa Swistak 1 collaboration

Sara Sagadiev 1 collaboration

Mridu Acharya 1 collaboration

Caroline Demeret 1 collaboration

Sylvie Van Der Werf 1 collaboration

Florence Guivel-Benhassine 1 collaboration

Olivier Schwartz 1 collaboration

Serena Petracchini 1 collaboration

Amel Mettouchi 1 collaboration

Lucie Caramelle 1 collaboration

Pierre Couvineau 1 collaboration

Robert Thai 1 collaboration

Peggy Barbe 1 collaboration

Mathilde Keck 1 collaboration

Priscille Brodin 1 collaboration

Arnaud Machelart 1 collaboration

Valentin Sencio 1 collaboration

François Trottein 1 collaboration

Martin Sachse 1 collaboration

Florian Ville 1 collaboration

Victor Kreis 1 collaboration

Michel-Robert Popoff 1 collaboration

Ludger Johannes 1 collaboration

Jean-Christophe Cintrat 1 collaboration

Julien Barbier 1 collaboration

Daniel Gillet 1 collaboration

Emmanuel Lemichez 1 collaboration

Anne Mazars 1 collaboration

Rémy Flores-Flores 1 collaboration

Marta Guerrero-Valero 1 collaboration

Federica Grandi 1 collaboration

Silvia Cipriani 1 collaboration

Valeria Alberizzi 1 collaboration

Roberta Di Guardo 1 collaboration

Linda Sawade 1 collaboration

Francesca Bianchi 1 collaboration

Ubaldo Del Carro 1 collaboration

Ivan De Curtis 1 collaboration

Davide Pareyson 1 collaboration

Yesim Parman 1 collaboration

Angelo Schenone 1 collaboration

Volker Haucke 1 collaboration

Alessandra Bolino 1 collaboration

Déborah Michel 1 collaboration

Adrien Antkowiak 1 collaboration

Elodie Vega 1 collaboration

Sara A Courtneidge 1 collaboration

Henri de la Salle 1 collaboration

Catherine Léon 1 collaboration

Cédric Garcia 1 collaboration

Nassima Chouaki Benmansour 1 collaboration

Kilian Ruminski 1 collaboration

Anne-Marie Sartre 1 collaboration

Marie-Claire Phelipot 1 collaboration

Audrey Salles 1 collaboration

Elise Bergot 1 collaboration

Ambroise Wu 1 collaboration

Mathieu Fallet 1 collaboration

Sophie Brustlein 1 collaboration

Cyrille Billaudeau 1 collaboration

Anthony Formisano 1 collaboration

Sébastien Mailfert 1 collaboration

Didier Marguet 1 collaboration

Sophie Brasselet 1 collaboration

Yannick Hamon 1 collaboration

Hai-Tao He 1 collaboration

Jonathan Clark 1 collaboration

Maria N Barrachina 1 collaboration

Anaelle Durbec 1 collaboration

Sara Troitiño 1 collaboration

Lidia Hermida-Nogueira 1 collaboration

Aurelio M Sueiro 1 collaboration

María Pardo 1 collaboration

Ángel García 1 collaboration

Marie Bellio 1 collaboration

Typhaine Anquetil 1 collaboration

Romain Solinhac 1 collaboration

Aude Jaffre 1 collaboration

Cyrille Orset 1 collaboration

Eva Geuss 1 collaboration

Christoph Kleinschnitz 1 collaboration

Denis Vivien 1 collaboration

Vincent Larrue 1 collaboration

Virginie Nahoum 1 collaboration

Fabienne Briand-Mésange 1 collaboration

Véronique Pons 1 collaboration

Julien Masquelier 1 collaboration

Nicolas Beton 1 collaboration

Giulio G Muccioli 1 collaboration

Jérôme Ausseil 1 collaboration

Jean-Luc Davignon 1 collaboration

Jean-Pierre Salles 1 collaboration

Hugues Chap 1 collaboration

Rana Mansour 1 collaboration

Frédéric Boal 1 collaboration

Hélène Tronchère 1 collaboration

Jonathan R Volpatti 1 collaboration

Mehdi M Ghahramani-Seno 1 collaboration

Nesrin Sabha 1 collaboration

Ege Sarikaya 1 collaboration

Sarah J Goodman 1 collaboration

Eric Chater-Diehl 1 collaboration

Alper Celik 1 collaboration

Emanuela Pannia 1 collaboration

Carine Froment 1 collaboration

Lucie Combes-Soia 1 collaboration

Nika Maani 1 collaboration

Kyoko E Yuki 1 collaboration

Liis Uusküla-Reimand 1 collaboration

Simon Monis 1 collaboration

Sana Akhtar Alvi 1 collaboration

Casie A Genetti 1 collaboration

Alan H Beggs 1 collaboration

Carsten G Bonnemann 1 collaboration

Francesco Muntoni 1 collaboration

Michael D Wilson 1 collaboration

Rosanna Weksberg 1 collaboration

James J Dowling 1 collaboration

Alessandra Consonni 1 collaboration

Xènia Massana-Muñoz 1 collaboration

Marie Goret 1 collaboration

Vasugi Nattarayan 1 collaboration

David Reiss 1 collaboration

Christine Kretz 1 collaboration

Jocelyn Laporte 1 collaboration

Laura Bouvet 1 collaboration

Maxime Borret 1 collaboration