Hartmut Oschkinat

Affiliations

Leibniz-Forschungsinstitut für Molekulare Pharmakologie, im Forschungsverbund Berlin e.V. (FMP), Campus Berlin-Buch, Robert-Rössle-Str. 10, 13125, Berlin, Germany.
Freie Universität Berlin, Fachbereich Biologie, Chemie und Pharmazie, Takustraße 3, 14195, Berlin, Germany.

Publications (21)

Pigmentation Chemistry and Radical-Based Collagen Degradation in Alkaptonuria and Osteoarthritic Cartilage.

Angewandte Chemie (International ed. in English)

Avec: Wing Ying Chow , Brendan P Norman , Norman B Roberts , Lakshminarayan R Ranganath , Christian Teutloff , Robert Bittl , Melinda J Duer , James A Gallagher , Hartmut Oschkinat

Collective exchange processes reveal an active site proton cage in bacteriorhodopsin.

Communications biology

Avec: Daniel Friedrich , Florian N Brünig , Andrew J Nieuwkoop , Roland R Netz , Peter Hegemann , Hartmut Oschkinat

NMR structure and dynamics of Q4DY78, a conserved kinetoplasid-specific protein from Trypanosoma cruzi.

Journal of structural biology

Avec: Éverton Dias D'Andréa , Joren Sebastian Retel , Anne Diehl , Peter Schmieder , Hartmut Oschkinat , José Ricardo Pires

Similarities and Differences among Protein Dynamics Studied by Variable Temperature Nuclear Magnetic Resonance Relaxation.

The journal of physical chemistry. B

Avec: Baptiste Busi , Jayasubba Reddy Yarava , Andrea Bertarello , François Freymond , Wiktor Adamski , Damien Maurin , Matthias Hiller , Hartmut Oschkinat , Martin Blackledge , Lyndon Emsley

Detection of nucleic acids and other low abundance components in native bone and osteosarcoma extracellular matrix by isotope enrichment and DNP-enhanced NMR.

RSC advances

Avec: Ieva Goldberga , Rui Li , Wing Ying Chow , David G Reid , Ulyana Bashtanova , Rakesh Rajan , Anna Puszkarska , Hartmut Oschkinat , Melinda J Duer

TapA acts as specific chaperone in TasA filament formation by strand complementation.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Yvette Roske , Florian Lindemann , Anne Diehl , Nils Cremer , Victoria A Higman , Brigitte Schlegel , Martina Leidert , Kristina Driller , Kürşad Turgay , Peter Schmieder , Udo Heinemann , Hartmut Oschkinat

Protein resonance assignment by BSH-CP-based 3D solid-state NMR experiments: A practical guide.

Magnetic resonance in chemistry : MRC

Avec: Jutta Hoffmann , Julia Ruta , Chaowei Shi , Kitty Hendriks , Veniamin Chevelkov , W Trent Franks , Hartmut Oschkinat , Karin Giller , Stefan Becker , Adam Lange

Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Matthias Barone , Matthias Müller , Slim Chiha , Jiang Ren , Dominik Albat , Arne Soicke , Stephan Dohmen , Marco Klein , Judith Bruns , Maarten van Dinther , Robert Opitz , Peter Lindemann , Monika Beerbaum , Kathrin Motzny , Yvette Roske , Peter Schmieder , Rudolf Volkmer , Marc Nazaré , Udo Heinemann , Hartmut Oschkinat , Peter Ten Dijke , Hans-Günther Schmalz , Ronald Kühne

Mechanism of threonine ADP-ribosylation of F-actin by a Tc toxin.

Nature communications

Avec: Alexander Belyy , Florian Lindemann , Daniel Roderer , Johanna Funk , Benjamin Bardiaux , Jonas Protze , Peter Bieling , Hartmut Oschkinat , Stefan Raunser

Sedimentation of large, soluble proteins up to 140 kDa for

Journal of biomolecular NMR

Avec: Dallas Bell , Florian Lindemann , Lisa Gerland , Hanna Aucharova , Alexander Klein , Daniel Friedrich , Matthias Hiller , Kristof Grohe , Tobias Meier , Barth van Rossum , Anne Diehl , Jon Hughes , Leonard J Mueller , Rasmus Linser , Anne-Frances Miller , Hartmut Oschkinat

Crystal structure of Q4D6Q6, a conserved kinetoplastid-specific protein from Trypanosoma cruzi.

Journal of structural biology

Avec: Éverton Dias D'Andréa , Yvette Roske , Guilherme A P de Oliveira , Nils Cremer , Anne Diehl , Peter Schmieder , Udo Heinemann , Hartmut Oschkinat , José Ricardo Pires

NMR quality control of fragment libraries for screening.

Journal of biomolecular NMR

Avec: Sridhar Sreeramulu , Christian Richter , Till Kuehn , Kamal Azzaoui , Marcel Jules José Blommers , Rebecca Del Conte , Marco Fragai , Nils Trieloff , Peter Schmieder , Marc Nazaré , Edgar Specker , Vladimir Ivanov , Hartmut Oschkinat , Lucia Banci , Harald Schwalbe

An Integrated Pharmacological, Structural, and Genetic Analysis of Extracellular Versus Intracellular ROS Production in Neutrophils.

Journal of molecular biology

Avec: Christian D Ellson , Ingred Goretti Riça , Jacob S Kim , Yu-Ming M Huang , Daniel Lim , Tanya Mitra , Albert Hsu , Erin X Wei , Christopher D Barrett , Leo E Otterbein , Carl J Hauser , Martin Wahl , Heinrich Delbrück , Udo Heinemann , Hartmut Oschkinat , Chia-En A Chang , Michael B Yaffe

Small-molecule inhibitors of the PDZ domain of Dishevelled proteins interrupt Wnt signalling.

Magnetic resonance (Gottingen, Germany)

Avec: Nestor Kamdem , Yvette Roske , Dmytro Kovalskyy , Maxim O Platonov , Oleksii Balinskyi , Annika Kreuchwig , Jörn Saupe , Liang Fang , Anne Diehl , Peter Schmieder , Gerd Krause , Jörg Rademann , Udo Heinemann , Walter Birchmeier , Hartmut Oschkinat

Sedimentation of large, soluble proteins up to 140 kDa for

Research square

Avec: Dallas Bell , Florian Lindemann , Lisa Gerland , Hanna Aucharova , Alexander Klein , Daniel Friedrich , Matthias Hiller , Kristof Grohe , Barth van Rossum , Anne Diehl , Jon Hughes , Leonard J Mueller , Rasmus Linser , Anne-Frances Miller , Hartmut Oschkinat

Dynamic Nuclear Polarization Magic-Angle Spinning Nuclear Magnetic Resonance Combined with Molecular Dynamics Simulations Permits Detection of Order and Disorder in Viral Assemblies.

The journal of physical chemistry. B

Avec: Rupal Gupta , Huilan Zhang , Manman Lu , Guangjin Hou , Marc Caporini , Melanie Rosay , Werner Maas , Jochem Struppe , Jinwoo Ahn , In-Ja L Byeon , Hartmut Oschkinat , Kristaps Jaudzems , Emeline Barbet-Massin , Lyndon Emsley , Guido Pintacuda , Anne Lesage , Angela M Gronenborn , Tatyana Polenova

The companion of cellulose synthase 1 confers salt tolerance through a Tau-like mechanism in plants.

Nature communications

Avec: Christopher Kesten , Arndt Wallmann , René Schneider , Heather E McFarlane , Anne Diehl , Ghazanfar Abbas Khan , Barth-Jan van Rossum , Edwin R Lampugnani , Witold G Szymanski , Nils Cremer , Peter Schmieder , Kristina L Ford , Florian Seiter , Joshua L Heazlewood , Clara Sanchez-Rodriguez , Hartmut Oschkinat , Staffan Persson

DNP NMR of biomolecular assemblies.

Journal of structural biology

Avec: Kristaps Jaudzems , Tatyana Polenova , Guido Pintacuda , Hartmut Oschkinat , Anne Lesage

Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization.

Cell reports

Avec: Karin H Müller , Robert Hayward , Rakesh Rajan , Meredith Whitehead , Andrew M Cobb , Sadia Ahmad , Mengxi Sun , Ieva Goldberga , Rui Li , Uliana Bashtanova , Anna M Puszkarska , David G Reid , Roger A Brooks , Jeremy N Skepper , Jayanta Bordoloi , Wing Ying Chow , Hartmut Oschkinat , Alex Groombridge , Oren A Scherman , James A Harrison , Anja Verhulst , Patrick C D'Haese , Ellen Neven , Lisa-Maria Needham , Steven F Lee , Catherine M Shanahan , Melinda J Duer

pH-Dependent Protonation of Surface Carboxylate Groups in PsbO Enables Local Buffering and Triggers Structural Changes.

Chembiochem : a European journal of chemical biology

Avec: Lisa Gerland , Daniel Friedrich , Linus Hopf , Eavan J Donovan , Arndt Wallmann , Natalja Erdmann , Anne Diehl , Martin Bommer , Krzysztof Buzar , Mohamed Ibrahim , Peter Schmieder , Holger Dobbek , Athina Zouni , Ana-Nicoleta Bondar , Holger Dau , Hartmut Oschkinat

MAS NMR detection of hydrogen bonds for protein secondary structure characterization.

Journal of biomolecular NMR

Avec: Daniel Friedrich , Jacqueline Perodeau , Andrew J Nieuwkoop , Hartmut Oschkinat

Réseau de co-auteurs

Anne Diehl 8 collaborations

Peter Schmieder 8 collaborations

Daniel Friedrich 5 collaborations

Udo Heinemann 5 collaborations

Yvette Roske 4 collaborations

Florian Lindemann 4 collaborations

Wing Ying Chow 3 collaborations

Melinda J Duer 3 collaborations

Matthias Hiller 3 collaborations

Nils Cremer 3 collaborations

Lisa Gerland 3 collaborations

Andrew J Nieuwkoop 2 collaborations

Éverton Dias D'Andréa 2 collaborations

José Ricardo Pires 2 collaborations

Lyndon Emsley 2 collaborations

Ieva Goldberga 2 collaborations

Rui Li 2 collaborations

David G Reid 2 collaborations

Rakesh Rajan 2 collaborations

Marc Nazaré 2 collaborations

Dallas Bell 2 collaborations

Hanna Aucharova 2 collaborations

Alexander Klein 2 collaborations

Kristof Grohe 2 collaborations

Barth van Rossum 2 collaborations

Jon Hughes 2 collaborations

Leonard J Mueller 2 collaborations

Rasmus Linser 2 collaborations

Anne-Frances Miller 2 collaborations

Kristaps Jaudzems 2 collaborations

Guido Pintacuda 2 collaborations

Anne Lesage 2 collaborations

Tatyana Polenova 2 collaborations

Arndt Wallmann 2 collaborations

Brendan P Norman 1 collaboration

Norman B Roberts 1 collaboration

Lakshminarayan R Ranganath 1 collaboration

Christian Teutloff 1 collaboration

Robert Bittl 1 collaboration

James A Gallagher 1 collaboration

Florian N Brünig 1 collaboration

Roland R Netz 1 collaboration

Peter Hegemann 1 collaboration

Joren Sebastian Retel 1 collaboration

Baptiste Busi 1 collaboration

Jayasubba Reddy Yarava 1 collaboration

Andrea Bertarello 1 collaboration

François Freymond 1 collaboration

Wiktor Adamski 1 collaboration

Damien Maurin 1 collaboration

Martin Blackledge 1 collaboration

Ulyana Bashtanova 1 collaboration

Anna Puszkarska 1 collaboration

Victoria A Higman 1 collaboration

Brigitte Schlegel 1 collaboration

Martina Leidert 1 collaboration

Kristina Driller 1 collaboration

Kürşad Turgay 1 collaboration

Jutta Hoffmann 1 collaboration

Julia Ruta 1 collaboration

Chaowei Shi 1 collaboration

Kitty Hendriks 1 collaboration

Veniamin Chevelkov 1 collaboration

W Trent Franks 1 collaboration

Karin Giller 1 collaboration

Stefan Becker 1 collaboration

Adam Lange 1 collaboration

Matthias Barone 1 collaboration

Matthias Müller 1 collaboration

Slim Chiha 1 collaboration

Jiang Ren 1 collaboration

Dominik Albat 1 collaboration

Arne Soicke 1 collaboration

Stephan Dohmen 1 collaboration

Marco Klein 1 collaboration

Judith Bruns 1 collaboration

Maarten van Dinther 1 collaboration

Robert Opitz 1 collaboration

Peter Lindemann 1 collaboration

Monika Beerbaum 1 collaboration

Kathrin Motzny 1 collaboration

Rudolf Volkmer 1 collaboration

Peter Ten Dijke 1 collaboration

Hans-Günther Schmalz 1 collaboration

Ronald Kühne 1 collaboration

Alexander Belyy 1 collaboration

Daniel Roderer 1 collaboration

Johanna Funk 1 collaboration

Benjamin Bardiaux 1 collaboration

Jonas Protze 1 collaboration

Peter Bieling 1 collaboration

Stefan Raunser 1 collaboration

Tobias Meier 1 collaboration

Guilherme A P de Oliveira 1 collaboration

Sridhar Sreeramulu 1 collaboration

Christian Richter 1 collaboration

Till Kuehn 1 collaboration

Kamal Azzaoui 1 collaboration

Marcel Jules José Blommers 1 collaboration

Rebecca Del Conte 1 collaboration

Marco Fragai 1 collaboration

Nils Trieloff 1 collaboration

Edgar Specker 1 collaboration

Vladimir Ivanov 1 collaboration

Lucia Banci 1 collaboration

Harald Schwalbe 1 collaboration

Christian D Ellson 1 collaboration

Ingred Goretti Riça 1 collaboration

Jacob S Kim 1 collaboration

Yu-Ming M Huang 1 collaboration

Daniel Lim 1 collaboration

Tanya Mitra 1 collaboration

Albert Hsu 1 collaboration

Erin X Wei 1 collaboration

Christopher D Barrett 1 collaboration

Leo E Otterbein 1 collaboration

Carl J Hauser 1 collaboration

Martin Wahl 1 collaboration

Heinrich Delbrück 1 collaboration

Chia-En A Chang 1 collaboration

Michael B Yaffe 1 collaboration

Nestor Kamdem 1 collaboration

Dmytro Kovalskyy 1 collaboration

Maxim O Platonov 1 collaboration

Oleksii Balinskyi 1 collaboration

Annika Kreuchwig 1 collaboration

Jörn Saupe 1 collaboration

Liang Fang 1 collaboration

Gerd Krause 1 collaboration

Jörg Rademann 1 collaboration

Walter Birchmeier 1 collaboration

Rupal Gupta 1 collaboration

Huilan Zhang 1 collaboration

Manman Lu 1 collaboration

Guangjin Hou 1 collaboration

Marc Caporini 1 collaboration

Melanie Rosay 1 collaboration

Werner Maas 1 collaboration

Jochem Struppe 1 collaboration

Jinwoo Ahn 1 collaboration

In-Ja L Byeon 1 collaboration

Emeline Barbet-Massin 1 collaboration

Angela M Gronenborn 1 collaboration

Christopher Kesten 1 collaboration

René Schneider 1 collaboration

Heather E McFarlane 1 collaboration

Ghazanfar Abbas Khan 1 collaboration

Barth-Jan van Rossum 1 collaboration

Edwin R Lampugnani 1 collaboration

Witold G Szymanski 1 collaboration

Kristina L Ford 1 collaboration

Florian Seiter 1 collaboration

Joshua L Heazlewood 1 collaboration

Clara Sanchez-Rodriguez 1 collaboration

Staffan Persson 1 collaboration

Karin H Müller 1 collaboration

Robert Hayward 1 collaboration

Meredith Whitehead 1 collaboration

Andrew M Cobb 1 collaboration

Sadia Ahmad 1 collaboration

Mengxi Sun 1 collaboration

Uliana Bashtanova 1 collaboration

Anna M Puszkarska 1 collaboration

Roger A Brooks 1 collaboration

Jeremy N Skepper 1 collaboration

Jayanta Bordoloi 1 collaboration

Alex Groombridge 1 collaboration

Oren A Scherman 1 collaboration

James A Harrison 1 collaboration

Anja Verhulst 1 collaboration

Patrick C D'Haese 1 collaboration

Ellen Neven 1 collaboration

Lisa-Maria Needham 1 collaboration

Steven F Lee 1 collaboration

Catherine M Shanahan 1 collaboration

Linus Hopf 1 collaboration

Eavan J Donovan 1 collaboration

Natalja Erdmann 1 collaboration

Martin Bommer 1 collaboration

Krzysztof Buzar 1 collaboration

Mohamed Ibrahim 1 collaboration

Holger Dobbek 1 collaboration

Athina Zouni 1 collaboration

Ana-Nicoleta Bondar 1 collaboration

Holger Dau 1 collaboration

Jacqueline Perodeau 1 collaboration