Jonathan R Brestoff

Affiliations

Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA. brestoff@wustl.edu.

ORCID: http://orcid.org/0000-0002-7018-7400

Publications (28)

Mitochondria transfer-based therapies reduce the morbidity and mortality of Leigh syndrome.

Nature metabolism

Avec: Ritsuko Nakai , Stella Varnum , Rachael L Field , Henyun Shi , Rocky Giwa , Wentong Jia , Samantha J Krysa , Eva F Cohen , Nicholas Borcherding , Russell P Saneto , Rick C Tsai , Masashi Suganuma , Hisashi Ohta , Takafumi Yokota , Jonathan R Brestoff

A type 2 immune circuit in the stomach controls mammalian adaptation to dietary chitin.

Science (New York, N.Y.)

Avec: Do-Hyun Kim , Yilin Wang , Haerin Jung , Rachael L Field , Xinya Zhang , Ta-Chiang Liu , Changqing Ma , James S Fraser , Jonathan R Brestoff , Steven J Van Dyken

Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure.

The Journal of clinical investigation

Avec: Wei Zou , Nidhi Rohatgi , Jonathan R Brestoff , John R Moley , Yongjia Li , Jesse W Williams , Yael Alippe , Hua Pan , Terri A Pietka , Gabriel Mbalaviele , Elizabeth P Newberry , Nicholas O Davidson , Anwesha Dey , Kooresh I Shoghi , Richard D Head , Samuel A Wickline , Gwendalyn J Randolph , Nada A Abumrad , Steven L Teitelbaum

Contemporary Challenges in Clinical Flow Cytometry: Small Samples, Big Data, Little Time.

The journal of applied laboratory medicine

Avec: Jonathan R Brestoff , John L Frater

Technological features of blast identification in the cerebrospinal fluid: A systematic review of flow cytometry and laboratory haematology methods.

International journal of laboratory hematology

Avec: John L Frater , Cara Lunn Shirai , Jonathan R Brestoff

Full spectrum flow cytometry in the clinical laboratory.

International journal of laboratory hematology

Avec: Jonathan R Brestoff

The power and potential of mitochondria transfer.

Nature

Avec: Nicholas Borcherding , Jonathan R Brestoff

Blood natural killer cell deficiency reveals an immunotherapy strategy for atopic dermatitis.

Science translational medicine

Avec: Madison R Mack , Jonathan R Brestoff , Melissa M Berrien-Elliott , Anna M Trier , Ting-Lin B Yang , Matthew McCullen , Patrick L Collins , Haixia Niu , Nancy D Bodet , Julia A Wagner , Eugene Park , Amy Z Xu , Fang Wang , Rebecca Chibnall , M Laurin Council , Carrie Heffington , Friederike Kreisel , David J Margolis , David Sheinbein , Paola Lovato , Eric Vivier , Marina Cella , Marco Colonna , Wayne M Yokoyama , Eugene M Oltz , Todd A Fehniger , Brian S Kim

Kinetic Approach Extends the Analytical Measurement Range and Corrects Antigen Excess in Homogeneous Turbidimetric Immunoassays.

The journal of applied laboratory medicine

Avec: Mark A Zaydman , Jonathan R Brestoff , Nicole Logsdon , Ann M Gronowski

Intercellular Mitochondria Transfer to Macrophages Regulates White Adipose Tissue Homeostasis and Is Impaired in Obesity.

Cell metabolism

Avec: Jonathan R Brestoff , Craig B Wilen , John R Moley , Yongjia Li , Wei Zou , Nicole P Malvin , Marina N Rowen , Brian T Saunders , Hongming Ma , Madison R Mack , Barry L Hykes , Dale R Balce , Anthony Orvedahl , Jesse W Williams , Nidhi Rohatgi , Xiaoyan Wang , Michael R McAllaster , Scott A Handley , Brian S Kim , John G Doench , Bernd H Zinselmeyer , Michael S Diamond , Herbert W Virgin , Andrew E Gelman , Steven L Teitelbaum

Lipid-associated macrophages reshape BAT cell identity in obesity.

Cell reports

Avec: Francesca Sciarretta , Andrea Ninni , Fabio Zaccaria , Valerio Chiurchiù , Adeline Bertola , Keaton Karlinsey , Wentong Jia , Veronica Ceci , Claudia Di Biagio , Ziyan Xu , Francesco Gaudioso , Flavia Tortolici , Marta Tiberi , Jiabi Zhang , Simone Carotti , Sihem Boudina , Paolo Grumati , Beiyan Zhou , Jonathan R Brestoff , Stoyan Ivanov , Katia Aquilano , Daniele Lettieri-Barbato

Brown Fat Fuels the Fire in Fever.

Journal of lipid research

Avec: Samantha J Krysa , Jonathan R Brestoff

Hepatic lipids promote liver metastasis.

JCI insight

Avec: Yongjia Li , Xinming Su , Nidhi Rohatgi , Yan Zhang , Jonathan R Brestoff , Kooresh I Shoghi , Yalin Xu , Clay F Semenkovich , Charles A Harris , Lindsay L Peterson , Katherine N Weilbaecher , Steven L Teitelbaum , Wei Zou

A systematic review and meta-analysis of obesity and COVID-19 outcomes.

Scientific reports

Avec: Xinya Zhang , Alexander M Lewis , John R Moley , Jonathan R Brestoff

Mitochondria Transfer to CD4

Immunometabolism

Avec: Rocky Giwa , Jonathan R Brestoff

Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue.

Cell metabolism

Avec: Marco Rosina , Veronica Ceci , Riccardo Turchi , Li Chuan , Nicholas Borcherding , Francesca Sciarretta , María Sánchez-Díaz , Flavia Tortolici , Keaton Karlinsey , Valerio Chiurchiù , Claudia Fuoco , Rocky Giwa , Rachael L Field , Matteo Audano , Simona Arena , Alessandro Palma , Federica Riccio , Farnaz Shamsi , Giovanni Renzone , Martina Verri , Anna Crescenzi , Salvatore Rizza , Fiorella Faienza , Giuseppe Filomeni , Sander Kooijman , Stefano Rufini , Antoine A F de Vries , Andrea Scaloni , Nico Mitro , Yu-Hua Tseng , Andrés Hidalgo , Beiyan Zhou , Jonathan R Brestoff , Katia Aquilano , Daniele Lettieri-Barbato

Adipocyte lipin 1 is positively associated with metabolic health in humans and regulates systemic metabolism in mice.

bioRxiv : the preprint server for biology

Avec: Andrew LaPoint , Jason M Singer , Daniel Ferguson , Trevor M Shew , M Katie Renkemeyer , Hector Palacios , Rachael Field , Mahalakshmi Shankaran , Gordon I Smith , Jun Yoshino , Mai He , Gary J Patti , Marc K Hellerstein , Samuel Klein , Jonathan R Brestoff , Brian N Finck , Andrew J Lutkewitte

Adipocyte lipin 1 expression associates with human metabolic health and regulates systemic metabolism in mice.

The Journal of clinical investigation

Avec: Andrew LaPoint , Jason M Singer , Daniel Ferguson , Trevor M Shew , M Katie Renkemeyer , Hector H Palacios , Rachael L Field , Sireeesha Yerrathota , Roshan Kumari , Mahalakshmi Shankaran , Gordon I Smith , Jun Yoshino , Mai He , Gary J Patti , Marc K Hellerstein , Samuel Klein , E Matthew Morris , Jonathan R Brestoff , Brian N Finck , Andrew Lutkewitte

Bone Marrow Biopsy Needle Type Affects Core Biopsy Specimen Length and Quality and Aspirate Hemodilution.

American journal of clinical pathology

Avec: Jonathan R Brestoff , Angus Toland , Khalid Afaneh , Abraham J Qavi , Barbara Press , Peter Westervelt , Friederike Kreisel , Anjum Hassan

Fat-Produced Adipsin Regulates Inflammatory Arthritis.

Cell reports

Avec: Yongjia Li , Wei Zou , Jonathan R Brestoff , Nidhi Rohatgi , Xiaobo Wu , John P Atkinson , Charles A Harris , Steven L Teitelbaum

Congenital lipodystrophy induces severe osteosclerosis.

PLoS genetics

Avec: Wei Zou , Nidhi Rohatgi , Jonathan R Brestoff , Yan Zhang , Erica L Scheller , Clarissa S Craft , Michael D Brodt , Nicole Migotsky , Matthew J Silva , Charles A Harris , Steven L Teitelbaum

Using information theory to optimize a diagnostic threshold to match physician-ordering practice.

Journal of biomedical informatics

Avec: Mark A Zaydman , Jonathan R Brestoff , Ronald Jackups

Ablation of Fat Cells in Adult Mice Induces Massive Bone Gain.

Cell metabolism

Avec: Wei Zou , Nidhi Rohatgi , Jonathan R Brestoff , Yongjia Li , Ruteja A Barve , Eric Tycksen , Yung Kim , Matthew J Silva , Steven L Teitelbaum

Dietary lipids inhibit mitochondria transfer to macrophages to divert adipocyte-derived mitochondria into the blood.

Cell metabolism

Avec: Nicholas Borcherding , Wentong Jia , Rocky Giwa , Rachael L Field , John R Moley , Benjamin J Kopecky , Mandy M Chan , Bin Q Yang , Jessica M Sabio , Emma C Walker , Omar Osorio , Andrea L Bredemeyer , Terri Pietka , Jennifer Alexander-Brett , Sharon Celeste Morley , Maxim N Artyomov , Nada A Abumrad , Joel Schilling , Kory Lavine , Clair Crewe , Jonathan R Brestoff

Multifaceted mitochondrial quality control in brown adipose tissue.

Trends in cell biology

Avec: Katia Aquilano , Beiyan Zhou , Jonathan R Brestoff , Daniele Lettieri-Barbato

A Single Reference Interval for Interpreting Serum Free Light Chains across Patients with Varying Renal Function.

Clinical chemistry

Avec: Vahid Azimi , Michael Slade , Mark Fiala , Julie M Fortier , Keith Stockerl-Goldstein , John L Frater , Jonathan R Brestoff , Ronald Jackups , Mark A Zaydman

Induction of a torpor-like hypothermic and hypometabolic state in rodents by ultrasound.

Nature metabolism

Avec: Yaoheng Yang , Jinyun Yuan , Rachael L Field , Dezhuang Ye , Zhongtao Hu , Kevin Xu , Lu Xu , Yan Gong , Yimei Yue , Alexxai V Kravitz , Michael R Bruchas , Jianmin Cui , Jonathan R Brestoff , Hong Chen

Cardiac Troponin to Adjudicate Subclinical Heart Failure in Diabetic Patients and a Murine Model of Metabolic Syndrome.

The journal of applied laboratory medicine

Avec: Hannah M Brown , Nicholas C Spies , Wentong Jia , John Moley , Sydney Lawless , Brittany Roemmich , Jonathan R Brestoff , Mark A Zaydman , Christopher W Farnsworth

Réseau de co-auteurs

Rachael L Field 6 collaborations

Wei Zou 6 collaborations

Nidhi Rohatgi 6 collaborations

Steven L Teitelbaum 6 collaborations

Yongjia Li 5 collaborations

Rocky Giwa 4 collaborations

Wentong Jia 4 collaborations

Nicholas Borcherding 4 collaborations

John R Moley 4 collaborations

Mark A Zaydman 4 collaborations

John L Frater 3 collaborations

Beiyan Zhou 3 collaborations

Katia Aquilano 3 collaborations

Daniele Lettieri-Barbato 3 collaborations

Charles A Harris 3 collaborations

Samantha J Krysa 2 collaborations

Xinya Zhang 2 collaborations

Jesse W Williams 2 collaborations

Kooresh I Shoghi 2 collaborations

Nada A Abumrad 2 collaborations

Madison R Mack 2 collaborations

Friederike Kreisel 2 collaborations

Brian S Kim 2 collaborations

Francesca Sciarretta 2 collaborations

Valerio Chiurchiù 2 collaborations

Keaton Karlinsey 2 collaborations

Veronica Ceci 2 collaborations

Flavia Tortolici 2 collaborations

Yan Zhang 2 collaborations

Andrew LaPoint 2 collaborations

Jason M Singer 2 collaborations

Daniel Ferguson 2 collaborations

Trevor M Shew 2 collaborations

M Katie Renkemeyer 2 collaborations

Mahalakshmi Shankaran 2 collaborations

Gordon I Smith 2 collaborations

Jun Yoshino 2 collaborations

Mai He 2 collaborations

Gary J Patti 2 collaborations

Marc K Hellerstein 2 collaborations

Samuel Klein 2 collaborations

Brian N Finck 2 collaborations

Matthew J Silva 2 collaborations

Ronald Jackups 2 collaborations

Ritsuko Nakai 1 collaboration

Stella Varnum 1 collaboration

Henyun Shi 1 collaboration

Eva F Cohen 1 collaboration

Russell P Saneto 1 collaboration

Rick C Tsai 1 collaboration

Masashi Suganuma 1 collaboration

Hisashi Ohta 1 collaboration

Takafumi Yokota 1 collaboration

Do-Hyun Kim 1 collaboration

Yilin Wang 1 collaboration

Haerin Jung 1 collaboration

Ta-Chiang Liu 1 collaboration

Changqing Ma 1 collaboration

James S Fraser 1 collaboration

Steven J Van Dyken 1 collaboration

Yael Alippe 1 collaboration

Hua Pan 1 collaboration

Terri A Pietka 1 collaboration

Gabriel Mbalaviele 1 collaboration

Elizabeth P Newberry 1 collaboration

Nicholas O Davidson 1 collaboration

Anwesha Dey 1 collaboration

Richard D Head 1 collaboration

Samuel A Wickline 1 collaboration

Gwendalyn J Randolph 1 collaboration

Cara Lunn Shirai 1 collaboration

Melissa M Berrien-Elliott 1 collaboration

Anna M Trier 1 collaboration

Ting-Lin B Yang 1 collaboration

Matthew McCullen 1 collaboration

Patrick L Collins 1 collaboration

Haixia Niu 1 collaboration

Nancy D Bodet 1 collaboration

Julia A Wagner 1 collaboration

Eugene Park 1 collaboration

Amy Z Xu 1 collaboration

Fang Wang 1 collaboration

Rebecca Chibnall 1 collaboration

M Laurin Council 1 collaboration

Carrie Heffington 1 collaboration

David J Margolis 1 collaboration

David Sheinbein 1 collaboration

Paola Lovato 1 collaboration

Eric Vivier 1 collaboration

Marina Cella 1 collaboration

Marco Colonna 1 collaboration

Wayne M Yokoyama 1 collaboration

Eugene M Oltz 1 collaboration

Todd A Fehniger 1 collaboration

Nicole Logsdon 1 collaboration

Ann M Gronowski 1 collaboration

Craig B Wilen 1 collaboration

Nicole P Malvin 1 collaboration

Marina N Rowen 1 collaboration

Brian T Saunders 1 collaboration

Hongming Ma 1 collaboration

Barry L Hykes 1 collaboration

Dale R Balce 1 collaboration

Anthony Orvedahl 1 collaboration

Xiaoyan Wang 1 collaboration

Michael R McAllaster 1 collaboration

Scott A Handley 1 collaboration

John G Doench 1 collaboration

Bernd H Zinselmeyer 1 collaboration

Michael S Diamond 1 collaboration

Herbert W Virgin 1 collaboration

Andrew E Gelman 1 collaboration

Andrea Ninni 1 collaboration

Fabio Zaccaria 1 collaboration

Adeline Bertola 1 collaboration

Claudia Di Biagio 1 collaboration

Ziyan Xu 1 collaboration

Francesco Gaudioso 1 collaboration

Marta Tiberi 1 collaboration

Jiabi Zhang 1 collaboration

Simone Carotti 1 collaboration

Sihem Boudina 1 collaboration

Paolo Grumati 1 collaboration

Stoyan Ivanov 1 collaboration

Xinming Su 1 collaboration

Yalin Xu 1 collaboration

Clay F Semenkovich 1 collaboration

Lindsay L Peterson 1 collaboration

Katherine N Weilbaecher 1 collaboration

Alexander M Lewis 1 collaboration

Marco Rosina 1 collaboration

Riccardo Turchi 1 collaboration

Li Chuan 1 collaboration

María Sánchez-Díaz 1 collaboration

Claudia Fuoco 1 collaboration

Matteo Audano 1 collaboration

Simona Arena 1 collaboration

Alessandro Palma 1 collaboration

Federica Riccio 1 collaboration

Farnaz Shamsi 1 collaboration

Giovanni Renzone 1 collaboration

Martina Verri 1 collaboration

Anna Crescenzi 1 collaboration

Salvatore Rizza 1 collaboration

Fiorella Faienza 1 collaboration

Giuseppe Filomeni 1 collaboration

Sander Kooijman 1 collaboration

Stefano Rufini 1 collaboration

Antoine A F de Vries 1 collaboration

Andrea Scaloni 1 collaboration

Nico Mitro 1 collaboration

Yu-Hua Tseng 1 collaboration

Andrés Hidalgo 1 collaboration

Hector Palacios 1 collaboration

Rachael Field 1 collaboration

Andrew J Lutkewitte 1 collaboration

Hector H Palacios 1 collaboration

Sireeesha Yerrathota 1 collaboration

Roshan Kumari 1 collaboration

E Matthew Morris 1 collaboration

Andrew Lutkewitte 1 collaboration

Angus Toland 1 collaboration

Khalid Afaneh 1 collaboration

Abraham J Qavi 1 collaboration

Barbara Press 1 collaboration

Peter Westervelt 1 collaboration

Anjum Hassan 1 collaboration

Xiaobo Wu 1 collaboration

John P Atkinson 1 collaboration

Erica L Scheller 1 collaboration

Clarissa S Craft 1 collaboration

Michael D Brodt 1 collaboration

Nicole Migotsky 1 collaboration

Ruteja A Barve 1 collaboration

Eric Tycksen 1 collaboration

Yung Kim 1 collaboration

Benjamin J Kopecky 1 collaboration

Mandy M Chan 1 collaboration

Bin Q Yang 1 collaboration

Jessica M Sabio 1 collaboration

Emma C Walker 1 collaboration

Omar Osorio 1 collaboration

Andrea L Bredemeyer 1 collaboration

Terri Pietka 1 collaboration

Jennifer Alexander-Brett 1 collaboration

Sharon Celeste Morley 1 collaboration

Maxim N Artyomov 1 collaboration

Joel Schilling 1 collaboration

Kory Lavine 1 collaboration

Clair Crewe 1 collaboration

Vahid Azimi 1 collaboration

Michael Slade 1 collaboration

Mark Fiala 1 collaboration

Julie M Fortier 1 collaboration

Keith Stockerl-Goldstein 1 collaboration

Yaoheng Yang 1 collaboration

Jinyun Yuan 1 collaboration

Dezhuang Ye 1 collaboration

Zhongtao Hu 1 collaboration

Kevin Xu 1 collaboration

Lu Xu 1 collaboration

Yan Gong 1 collaboration

Yimei Yue 1 collaboration

Alexxai V Kravitz 1 collaboration

Michael R Bruchas 1 collaboration

Jianmin Cui 1 collaboration

Hong Chen 1 collaboration

Hannah M Brown 1 collaboration

Nicholas C Spies 1 collaboration

John Moley 1 collaboration

Sydney Lawless 1 collaboration

Brittany Roemmich 1 collaboration

Christopher W Farnsworth 1 collaboration