Jonathan Reader

Affiliations

Michigan Alzheimer's Disease Research Center, Ann Arbor, MI, USA.
Department of Neurology, University of Michigan Medical School, Ann Arbor, MI, USA.

Publications (20)

Optimal 10-Aminoartemisinins With Potent Transmission-Blocking Capabilities for New Artemisinin Combination Therapies-Activities Against Blood Stage

Frontiers in chemistry

Avec: Ho Ning Wong , Vivian Padín-Irizarry , Mariëtte E van der Watt , Janette Reader , Wilna Liebenberg , Lubbe Wiesner , Peter Smith , Korina Eribez , Elizabeth A Winzeler , Dennis E Kyle , Lyn-Marie Birkholtz , Dina Coertzen , Richard K Haynes

Structure-Activity Relationship Studies and Plasmodium Life Cycle Profiling Identifies Pan-Active N-Aryl-3-trifluoromethyl Pyrido[1,2- a]benzimidazoles Which Are Efficacious in an in Vivo Mouse Model of Malaria.

Journal of medicinal chemistry

Avec: Godfrey Mayoka , Mathew Njoroge , John Okombo , Liezl Gibhard , Margarida Sanches-Vaz , Diana Fontinha , Lyn-Marie Birkholtz , Janette Reader , Mariëtte van der Watt , Theresa L Coetzer , Sonja Lauterbach , Alisje Churchyard , Belinda Bezuidenhout , Timothy J Egan , Clive Yeates , Sergio Wittlin , Miguel Prudêncio , Kelly Chibale

In vitro dual activity of Aloe marlothii roots and its chemical constituents against Plasmodium falciparum asexual and sexual stage parasites.

Journal of ethnopharmacology

Avec: Sephora Mutombo Mianda , Luke Invernizzi , Mariëtte E van der Watt , Janette Reader , Phanankosi Moyo , Lyn-Marié Birkholtz , Vinesh J Maharaj

Alzheimer's Disease and Related Dementias in Muslim Women: Recommendations for Culturally Sensitive Care.

Journal of Alzheimer's disease : JAD

Avec: Bilal Irfan , Ghadeer Ankouni , Jonathan Reader , Navid Seraji-Bozorgzad , Bruno Giordani , Kelly Bakulski , Arijit Bhaumik , Benjamin M Hampstead , Annalise Rahman-Filipiak

Identification of 2,4-Disubstituted Imidazopyridines as Hemozoin Formation Inhibitors with Fast-Killing Kinetics and

Journal of medicinal chemistry

Avec: André Horatscheck , Ana Andrijevic , Aloysius T Nchinda , Claire Le Manach , Tanya Paquet , Lutete Peguy Khonde , Jean Dam , Kailash Pawar , Dale Taylor , Nina Lawrence , Christel Brunschwig , Liezl Gibhard , Mathew Njoroge , Janette Reader , Mariëtte van der Watt , Kathryn Wicht , Ana Carolina C de Sousa , John Okombo , Keletso Maepa , Timothy J Egan , Lyn-Marie Birkholtz , Gregory S Basarab , Sergio Wittlin , Paul V Fish , Leslie J Street , James Duffy , Kelly Chibale

Antimalarial Benzimidazole Derivatives Incorporating Phenolic Mannich Base Side Chains Inhibit Microtubule and Hemozoin Formation: Structure-Activity Relationship and

Journal of medicinal chemistry

Avec: Godwin Akpeko Dziwornu , Dina Coertzen , Meta Leshabane , Constance M Korkor , Cleavon K Cloete , Mathew Njoroge , Liezl Gibhard , Nina Lawrence , Janette Reader , Mariëtte van der Watt , Sergio Wittlin , Lyn-Marie Birkholtz , Kelly Chibale

Epigenetic inhibitors target multiple stages of Plasmodium falciparum parasites.

Scientific reports

Avec: Nanika Coetzee , Hilde von Grüning , Daniel Opperman , Mariette van der Watt , Janette Reader , Lyn-Marié Birkholtz

Multistage Antiplasmodium Activity of Astemizole Analogues and Inhibition of Hemozoin Formation as a Contributor to Their Mode of Action.

ACS infectious diseases

Avec: Malkeet Kumar , John Okombo , Dickson Mambwe , Dale Taylor , Nina Lawrence , Janette Reader , Mariëtte van der Watt , Diana Fontinha , Margarida Sanches-Vaz , Belinda C Bezuidenhout , Sonja B Lauterbach , Dale Liebenberg , Lyn-Marie Birkholtz , Theresa L Coetzer , Miguel Prudêncio , Timothy J Egan , Sergio Wittlin , Kelly Chibale

EP4 and Class III β-Tubulin Expression in Uterine Smooth Muscle Tumors: Implications for Prognosis and Treatment.

Cancers

Avec: Jocelyn Reader , Amy K Harper , Teklu Legesse , Paul N Staats , Olga Goloubeva , Gautam G Rao , Amy Fulton , Dana M Roque

Eicosanoids in Cancer: Prostaglandin E

Frontiers in pharmacology

Avec: Mc Millan Ching , Jocelyn Reader , Amy M Fulton

Chemogenomic Fingerprints Associated with Stage-Specific Gametocytocidal Compound Action against Human Malaria Parasites.

ACS infectious diseases

Avec: Jandeli Niemand , Riëtte van Biljon , Mariëtte van der Watt , Ashleigh van Heerden , Janette Reader , Roelof van Wyk , Lindsey Orchard , Kelly Chibale , Manuel Llinás , Lyn-Marié Birkholtz

Structure-Activity Relationship Studies Reveal New Astemizole Analogues Active against

ACS medicinal chemistry letters

Avec: Dickson Mambwe , Malkeet Kumar , Richard Ferger , Dale Taylor , Mathew Njoroge , Dina Coertzen , Janette Reader , Mariëtte van der Watt , Lyn-Marie Birkholtz , Kelly Chibale

Adsorption to the Surface of Hemozoin Crystals: Structure-Based Design and Synthesis of Amino-Phenoxazine β-Hematin Inhibitors.

ChemMedChem

Avec: Tania Olivier , Leigh Loots , Michélle Kok , Marianne de Villiers , Janette Reader , Lyn-Marié Birkholtz , Gareth E Arnott , Katherine A de Villiers

The Chemokine Receptor CXCR3 Isoform B Drives Breast Cancer Stem Cells.

Breast cancer : basic and clinical research

Avec: Namita Kundu , Xinrong Ma , Regine Brox , Xiaoxuan Fan , Tyler Kochel , Jocelyn Reader , Nuska Tschammer , Amy Fulton

Hierarchical transcriptional control regulates Plasmodium falciparum sexual differentiation.

BMC genomics

Avec: Riëtte van Biljon , Roelof van Wyk , Heather J Painter , Lindsey Orchard , Janette Reader , Jandeli Niemand , Manuel Llinás , Lyn-Marie Birkholtz

Photodynamic Priming Improves the Anti-Migratory Activity of Prostaglandin E Receptor 4 Antagonist in Cancer Cells In Vitro.

Cancers

Avec: Aaron J Sorrin , Cindy Liu , Julia Cicalo , Jocelyn Reader , Daniel Najafali , Yuji Zhang , Dana M Roque , Huang-Chiao Huang

Benzimidazole Derivatives Are Potent against Multiple Life Cycle Stages of

ACS infectious diseases

Avec: Meta Leshabane , Godwin Akpeko Dziwornu , Dina Coertzen , Janette Reader , Phanankosi Moyo , Mariëtte van der Watt , Kelly Chisanga , Consolata Nsanzubuhoro , Richard Ferger , Erica Erlank , Nelius Venter , Lizette Koekemoer , Kelly Chibale , Lyn-Marie Birkholtz

New Amidated 3,6-Diphenylated Imidazopyridazines with Potent Antiplasmodium Activity Are Dual Inhibitors of

ACS infectious diseases

Avec: Peter Mubanga Cheuka , Luyanda Centani , Lauren B Arendse , Stephen Fienberg , Lynn Wambua , Shoneeze S Renga , Godwin Akpeko Dziwornu , Malkeet Kumar , Nina Lawrence , Dale Taylor , Sergio Wittlin , Dina Coertzen , Janette Reader , Mariette van der Watt , Lyn-Marie Birkholtz , Kelly Chibale

A Dynamic and Combinatorial Histone Code Drives Malaria Parasite Asexual and Sexual Development.

Molecular & cellular proteomics : MCP

Avec: Hilde von Grüning , Mariel Coradin , Mariel R Mendoza , Janette Reader , Simone Sidoli , Benjamin A Garcia , Lyn-Marié Birkholtz

The Artemiside-Artemisox-Artemisone-M1 Tetrad: Efficacies against Blood Stage

Pharmaceutics

Avec: Liezl Gibhard , Dina Coertzen , Janette Reader , Mariëtte E van der Watt , Lyn-Marie Birkholtz , Ho Ning Wong , Kevin T Batty , Richard K Haynes , Lubbe Wiesner

Réseau de co-auteurs

Janette Reader 15 collaborations

Lyn-Marie Birkholtz 10 collaborations

Kelly Chibale 8 collaborations

Mariëtte van der Watt 7 collaborations

Dina Coertzen 6 collaborations

Sergio Wittlin 5 collaborations

Lyn-Marié Birkholtz 5 collaborations

Mathew Njoroge 4 collaborations

Liezl Gibhard 4 collaborations

Dale Taylor 4 collaborations

Nina Lawrence 4 collaborations

Jocelyn Reader 4 collaborations

Mariëtte E van der Watt 3 collaborations

John Okombo 3 collaborations

Timothy J Egan 3 collaborations

Godwin Akpeko Dziwornu 3 collaborations

Malkeet Kumar 3 collaborations

Ho Ning Wong 2 collaborations

Lubbe Wiesner 2 collaborations

Richard K Haynes 2 collaborations

Margarida Sanches-Vaz 2 collaborations

Diana Fontinha 2 collaborations

Theresa L Coetzer 2 collaborations

Miguel Prudêncio 2 collaborations

Phanankosi Moyo 2 collaborations

Meta Leshabane 2 collaborations

Hilde von Grüning 2 collaborations

Mariette van der Watt 2 collaborations

Dickson Mambwe 2 collaborations

Amy Fulton 2 collaborations

Dana M Roque 2 collaborations

Jandeli Niemand 2 collaborations

Riëtte van Biljon 2 collaborations

Roelof van Wyk 2 collaborations

Lindsey Orchard 2 collaborations

Manuel Llinás 2 collaborations

Richard Ferger 2 collaborations

Vivian Padín-Irizarry 1 collaboration

Wilna Liebenberg 1 collaboration

Peter Smith 1 collaboration

Korina Eribez 1 collaboration

Elizabeth A Winzeler 1 collaboration

Dennis E Kyle 1 collaboration

Godfrey Mayoka 1 collaboration

Sonja Lauterbach 1 collaboration

Alisje Churchyard 1 collaboration

Belinda Bezuidenhout 1 collaboration

Clive Yeates 1 collaboration

Sephora Mutombo Mianda 1 collaboration

Luke Invernizzi 1 collaboration

Vinesh J Maharaj 1 collaboration

Bilal Irfan 1 collaboration

Ghadeer Ankouni 1 collaboration

Navid Seraji-Bozorgzad 1 collaboration

Bruno Giordani 1 collaboration

Kelly Bakulski 1 collaboration

Arijit Bhaumik 1 collaboration

Benjamin M Hampstead 1 collaboration

Annalise Rahman-Filipiak 1 collaboration

André Horatscheck 1 collaboration

Ana Andrijevic 1 collaboration

Aloysius T Nchinda 1 collaboration

Claire Le Manach 1 collaboration

Tanya Paquet 1 collaboration

Lutete Peguy Khonde 1 collaboration

Jean Dam 1 collaboration

Kailash Pawar 1 collaboration

Christel Brunschwig 1 collaboration

Kathryn Wicht 1 collaboration

Ana Carolina C de Sousa 1 collaboration

Keletso Maepa 1 collaboration

Gregory S Basarab 1 collaboration

Paul V Fish 1 collaboration

Leslie J Street 1 collaboration

James Duffy 1 collaboration

Constance M Korkor 1 collaboration

Cleavon K Cloete 1 collaboration

Nanika Coetzee 1 collaboration

Daniel Opperman 1 collaboration

Belinda C Bezuidenhout 1 collaboration

Sonja B Lauterbach 1 collaboration

Dale Liebenberg 1 collaboration

Amy K Harper 1 collaboration

Teklu Legesse 1 collaboration

Paul N Staats 1 collaboration

Olga Goloubeva 1 collaboration

Gautam G Rao 1 collaboration

Mc Millan Ching 1 collaboration

Amy M Fulton 1 collaboration

Ashleigh van Heerden 1 collaboration

Tania Olivier 1 collaboration

Leigh Loots 1 collaboration

Michélle Kok 1 collaboration

Marianne de Villiers 1 collaboration

Gareth E Arnott 1 collaboration

Katherine A de Villiers 1 collaboration

Namita Kundu 1 collaboration

Xinrong Ma 1 collaboration

Regine Brox 1 collaboration

Xiaoxuan Fan 1 collaboration

Tyler Kochel 1 collaboration

Nuska Tschammer 1 collaboration

Heather J Painter 1 collaboration

Aaron J Sorrin 1 collaboration

Cindy Liu 1 collaboration

Julia Cicalo 1 collaboration

Daniel Najafali 1 collaboration

Yuji Zhang 1 collaboration

Huang-Chiao Huang 1 collaboration

Kelly Chisanga 1 collaboration

Consolata Nsanzubuhoro 1 collaboration

Erica Erlank 1 collaboration

Nelius Venter 1 collaboration

Lizette Koekemoer 1 collaboration

Peter Mubanga Cheuka 1 collaboration

Luyanda Centani 1 collaboration

Lauren B Arendse 1 collaboration

Stephen Fienberg 1 collaboration

Lynn Wambua 1 collaboration

Shoneeze S Renga 1 collaboration

Mariel Coradin 1 collaboration

Mariel R Mendoza 1 collaboration

Simone Sidoli 1 collaboration

Benjamin A Garcia 1 collaboration

Kevin T Batty 1 collaboration