Laynie Dratch

Affiliations

From the Department of Neurology (A.B., J.C., M.A., L.D., K.J., R.A.P., D.A.A., M.B., A.D., L.B.E., M.G., A.G.H., D.J.I., A.L., J.O.-M., C.C.Q., T.F.T., S.S.S., R.H.H., C.A.E.), Penn Statistics in Imaging and Visualization Center (PennSIVE) (R.T.S.), Department of Biostatistics, Epidemiology, and Informatics, and Center for Biomedical Image Computing and Analytics (R.T.S.), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.

ORCID: 0000-0002-2179-3199

Publications (17)

Disparities in Genetic Testing for Neurologic Disorders.

Neurology

Avec: Aaron Baldwin , Juliette Copeland , Meron Azage , Laynie Dratch , Kelsey Johnson , Rachel A Paul , Defne A Amado , Michael Baer , Andres Deik , Lauren B Elman , Michael Guo , Ali G Hamedani , David J Irwin , Aaron Lasker , Jennifer Orthmann-Murphy , Colin C Quinn , Thomas F Tropea , Steven S Scherer , Russell T Shinohara , Roy H Hamilton , Colin A Ellis

Genetic testing in adults with neurologic disorders: indications, approach, and clinical impacts.

Journal of neurology

Avec: Laynie Dratch , Meron Azage , Aaron Baldwin , Kelsey Johnson , Rachel A Paul , Tanya M Bardakjian , Sara-Claude Michon , Defne A Amado , Michael Baer , Andres F Deik , Lauren B Elman , Pedro Gonzalez-Alegre , Michael H Guo , Ali G Hamedani , David J Irwin , Aaron Lasker , Jennifer Orthmann-Murphy , Colin Quinn , Thomas F Tropea , Steven S Scherer , Colin A Ellis

The lived experience of reconstructing identity in response to genetic risk of frontotemporal degeneration and amyotrophic lateral sclerosis.

Journal of genetic counseling

Avec: Laynie Dratch , Jill Owczarzak , Weiyi Mu , Katheryn A Q Cousins , Lauren Massimo , Murray Grossman , Lori Erby

Expanding Genetic Counselor Roles: A Model for Global Research Development.

Genes

Avec: Colleen C Muraresku , Elizabeth M McCormick , Lydia Rockart , T Blaine Crowley , Stephanie Asher , Amanda Back , Sarah M Baldino , Emma Bedoukian , Allison D Britt , Natalie Burrill , Cara Cacioppo , Dana Farengo Clark , Mary Egan Clark , Laura Conway , Laynie Dratch , Holly A Dubbs , Nicole M Engelhardt , Natalie Ginn , Christopher Gray , Tiff Hartman , Evan R Hathaway , Katherine L Helbig , Lily Hoffman-Andrews , Stefanie Kasperski , Beth A Keena , Kierstin N Keller , Jessica M Long , Lauren Lulis , Laina Lusk , Daniel E McGinn , Rebecca Mueller , Rache A Paul , Lisa Pilchman , Jacquelyn Powers , Sarah E Raible , Sara Reichert , Alyssa L Rippert , Angela G Arnold , Sarah M Ruggiero , Erica Schindewolf , Katie Rose Sullivan , Shannon Terek , Bekah Wang , McKenzie Wells , Natalia Wisniewski , Renee Wright , Elisabeth McCarty Wood , Stacy Woyciechowski , Kristin Zelley , Kathleen D Valverde , Donna M McDonald-McGinn

Enhancing Clinical Infrastructure for the Delivery of Intrathecal and Genetic Therapies: A Qalsody (Tofersen) Model for Patients With

Neurology. Clinical practice

Avec: Jennifer Morganroth , Tanya M Bardakjian , Laynie Dratch , Colin C Quinn , Lauren B Elman

Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration.

Acta neuropathologica

Avec: Lucia A A Giannini , Daniel T Ohm , Annemieke J M Rozemuller , Laynie Dratch , EunRan Suh , Vivianna M van Deerlin , John Q Trojanowski , Edward B Lee , John C van Swieten , Murray Grossman , Harro Seelaar , David J Irwin , Auteur inconnu

Changes in Digital Speech Measures in Asymptomatic Carriers of Pathogenic Variants Associated With Frontotemporal Degeneration.

Neurology

Avec: Naomi Nevler , Sunghye Cho , Katheryn A Q Cousins , Sharon Ash , Christopher A Olm , Sanjana Shellikeri , Galit Agmon , Carmen Gonzalez-Recober , Sharon X Xie , Megan S Barker , Masood Manoochehri , Corey T Mcmillan , David J Irwin , Lauren Massimo , Laynie Dratch , Gayathri Cheran , Edward D Huey , Stephanie A Cosentino , Vivianna M Van Deerlin , Mark Y Liberman , Murray Grossman

Transitioning to telegenetics in the COVID-19 era: Patient satisfaction with remote genetic counseling in adult neurology.

Journal of genetic counseling

Avec: Laynie Dratch , Rachel A Paul , Aaron Baldwin , Morgan Brzozowski , Pedro Gonzalez-Alegre , Thomas F Tropea , Anna Raper , Tanya Bardakjian

Elevated Plasma Phosphorylated Tau 181 in Amyotrophic Lateral Sclerosis.

Annals of neurology

Avec: Katheryn A Q Cousins , Leslie M Shaw , Sanjana Shellikeri , Laynie Dratch , Luis Rosario , Lauren B Elman , Colin Quinn , Defne A Amado , David A Wolk , Thomas F Tropea , Alice Chen-Plotkin , David J Irwin , Murray Grossman , Edward B Lee , John Q Trojanowski , Corey T McMillan

The Importance of Offering Exome or Genome Sequencing in Adult Neuromuscular Clinics.

Biology

Avec: Laynie Dratch , Tanya M Bardakjian , Kelsey Johnson , Nareen Babaian , Pedro Gonzalez-Alegre , Lauren Elman , Colin Quinn , Michael H Guo , Steven S Scherer , Defne A Amado

C9orf72 repeat expansions modify risk for secondary motor and cognitive-behavioral symptoms in behavioral-variant frontotemporal degeneration and amyotrophic lateral sclerosis.

medRxiv : the preprint server for health sciences

Avec: Barbara E Spencer , Sharon X Xie , Lauren B Elman , Colin C Quinn , Defne Amado , Michael Baer , Edward B Lee , Vivianna Van Deerlin , Laynie Dratch , Lauren Massimo , David J Irwin , Corey T McMillan

Diagnostic and clinical utility of comprehensive multigene panel testing for patients with neuropathy.

Journal of the peripheral nervous system : JPNS

Avec: Jennifer Roggenbuck , Ana Morales , Colin A Ellis , Laynie Dratch , Molly Stetler , Christopher A Tan , Brianna Bucknor , Kathryn E Hatchell , Swaroop Aradhya , Edward D Esplin , Yi-Lee Ting , Steven S Scherer

Evaluation of an educational conference for persons affected by hereditary frontotemporal degeneration and amyotrophic lateral sclerosis.

PEC innovation

Avec: Laynie Dratch , Weiyi Mu , Elisabeth McCarty Wood , Brianna Morgan , Lauren Massimo , Cynthia Clyburn , Tanya Bardakjian , Murray Grossman , David J Irwin , Katheryn A Q Cousins

Preimplantation Genetic Testing for Adult-Onset Neurodegenerative Disease: Considerations for Access, Utilization, and Counseling.

Neurology

Avec: Rachel A Paul , Aaron Baldwin , Kelsey Johnson , Sara Manning Peskin , Thomas F Tropea , Meron Azage , Tanya Bardakjian , Laynie Dratch

Incorporating Genetic Testing Into the Care of Patients With Amyotrophic Lateral Sclerosis/Frontotemporal Degeneration Spectrum Disorders.

Neurology. Clinical practice

Avec: Chelsea Chambers , Lauren Lichten , Ashley Crook , Wendy R Uhlmann , Laynie Dratch

Disparate and shared transcriptomic signatures associated with cortical atrophy in genetic bvFTD.

medRxiv : the preprint server for health sciences

Avec: Ting Shen , Jacob W Vogel , Vivianna M Van Deerlin , EunRan Suh , Laynie Dratch , Jeffrey S Phillips , Lauren Massimo , Edward B Lee , David J Irwin , Corey T McMillan

The Miami Framework for ALS and related neurodegenerative disorders: an integrated view of phenotype and biology.

Nature reviews. Neurology

Avec: Michael Benatar , Joanne Wuu , Edward D Huey , Corey T McMillan , Ronald C Petersen , Ronald Postuma , Caroline McHutchison , Laynie Dratch , Jalayne J Arias , Anita Crawley , Henry Houlden , Michael P McDermott , Xueya Cai , Neil Thakur , Adam Boxer , Howard Rosen , Bradley F Boeve , Penny Dacks , Stephanie Cosentino , Sharon Abrahams , Neil Shneider , Paul Lingor , Jeremy Shefner , Peter M Andersen , Ammar Al-Chalabi , Martin R Turner , Auteur inconnu

Réseau de co-auteurs

David J Irwin 8 collaborations

Lauren B Elman 5 collaborations

Thomas F Tropea 5 collaborations

Lauren Massimo 5 collaborations

Murray Grossman 5 collaborations

Aaron Baldwin 4 collaborations

Kelsey Johnson 4 collaborations

Rachel A Paul 4 collaborations

Defne A Amado 4 collaborations

Steven S Scherer 4 collaborations

Katheryn A Q Cousins 4 collaborations

Edward B Lee 4 collaborations

Corey T McMillan 4 collaborations

Meron Azage 3 collaborations

Michael Baer 3 collaborations

Colin C Quinn 3 collaborations

Colin A Ellis 3 collaborations

Tanya M Bardakjian 3 collaborations

Pedro Gonzalez-Alegre 3 collaborations

Colin Quinn 3 collaborations

Tanya Bardakjian 3 collaborations

Ali G Hamedani 2 collaborations

Aaron Lasker 2 collaborations

Jennifer Orthmann-Murphy 2 collaborations

Michael H Guo 2 collaborations

Weiyi Mu 2 collaborations

Elisabeth McCarty Wood 2 collaborations

EunRan Suh 2 collaborations

John Q Trojanowski 2 collaborations

None None 2 collaborations

Sanjana Shellikeri 2 collaborations

Sharon X Xie 2 collaborations

Edward D Huey 2 collaborations

Vivianna M Van Deerlin 2 collaborations

Juliette Copeland 1 collaboration

Andres Deik 1 collaboration

Michael Guo 1 collaboration

Russell T Shinohara 1 collaboration

Roy H Hamilton 1 collaboration

Sara-Claude Michon 1 collaboration

Andres F Deik 1 collaboration

Jill Owczarzak 1 collaboration

Lori Erby 1 collaboration

Colleen C Muraresku 1 collaboration

Elizabeth M McCormick 1 collaboration

Lydia Rockart 1 collaboration

T Blaine Crowley 1 collaboration

Stephanie Asher 1 collaboration

Amanda Back 1 collaboration

Sarah M Baldino 1 collaboration

Emma Bedoukian 1 collaboration

Allison D Britt 1 collaboration

Natalie Burrill 1 collaboration

Cara Cacioppo 1 collaboration

Dana Farengo Clark 1 collaboration

Mary Egan Clark 1 collaboration

Laura Conway 1 collaboration

Holly A Dubbs 1 collaboration

Nicole M Engelhardt 1 collaboration

Natalie Ginn 1 collaboration

Christopher Gray 1 collaboration

Tiff Hartman 1 collaboration

Evan R Hathaway 1 collaboration

Katherine L Helbig 1 collaboration

Lily Hoffman-Andrews 1 collaboration

Stefanie Kasperski 1 collaboration

Beth A Keena 1 collaboration

Kierstin N Keller 1 collaboration

Jessica M Long 1 collaboration

Lauren Lulis 1 collaboration

Laina Lusk 1 collaboration

Daniel E McGinn 1 collaboration

Rebecca Mueller 1 collaboration

Rache A Paul 1 collaboration

Lisa Pilchman 1 collaboration

Jacquelyn Powers 1 collaboration

Sarah E Raible 1 collaboration

Sara Reichert 1 collaboration

Alyssa L Rippert 1 collaboration

Angela G Arnold 1 collaboration

Sarah M Ruggiero 1 collaboration

Erica Schindewolf 1 collaboration

Katie Rose Sullivan 1 collaboration

Shannon Terek 1 collaboration

Bekah Wang 1 collaboration

McKenzie Wells 1 collaboration

Natalia Wisniewski 1 collaboration

Renee Wright 1 collaboration

Stacy Woyciechowski 1 collaboration

Kristin Zelley 1 collaboration

Kathleen D Valverde 1 collaboration

Donna M McDonald-McGinn 1 collaboration

Jennifer Morganroth 1 collaboration

Lucia A A Giannini 1 collaboration

Daniel T Ohm 1 collaboration

Annemieke J M Rozemuller 1 collaboration

Vivianna M van Deerlin 1 collaboration

John C van Swieten 1 collaboration

Harro Seelaar 1 collaboration

Naomi Nevler 1 collaboration

Sunghye Cho 1 collaboration

Sharon Ash 1 collaboration

Christopher A Olm 1 collaboration

Galit Agmon 1 collaboration

Carmen Gonzalez-Recober 1 collaboration

Megan S Barker 1 collaboration

Masood Manoochehri 1 collaboration

Corey T Mcmillan 1 collaboration

Gayathri Cheran 1 collaboration

Stephanie A Cosentino 1 collaboration

Mark Y Liberman 1 collaboration

Morgan Brzozowski 1 collaboration

Anna Raper 1 collaboration

Leslie M Shaw 1 collaboration

Luis Rosario 1 collaboration

David A Wolk 1 collaboration

Alice Chen-Plotkin 1 collaboration

Nareen Babaian 1 collaboration

Lauren Elman 1 collaboration

Barbara E Spencer 1 collaboration

Defne Amado 1 collaboration

Vivianna Van Deerlin 1 collaboration

Jennifer Roggenbuck 1 collaboration

Ana Morales 1 collaboration

Molly Stetler 1 collaboration

Christopher A Tan 1 collaboration

Brianna Bucknor 1 collaboration

Kathryn E Hatchell 1 collaboration

Swaroop Aradhya 1 collaboration

Edward D Esplin 1 collaboration

Yi-Lee Ting 1 collaboration

Brianna Morgan 1 collaboration

Cynthia Clyburn 1 collaboration

Sara Manning Peskin 1 collaboration

Chelsea Chambers 1 collaboration

Lauren Lichten 1 collaboration

Ashley Crook 1 collaboration

Wendy R Uhlmann 1 collaboration

Ting Shen 1 collaboration

Jacob W Vogel 1 collaboration

Jeffrey S Phillips 1 collaboration

Michael Benatar 1 collaboration

Joanne Wuu 1 collaboration

Ronald C Petersen 1 collaboration

Ronald Postuma 1 collaboration

Caroline McHutchison 1 collaboration

Jalayne J Arias 1 collaboration

Anita Crawley 1 collaboration

Henry Houlden 1 collaboration

Michael P McDermott 1 collaboration

Xueya Cai 1 collaboration

Neil Thakur 1 collaboration

Adam Boxer 1 collaboration

Howard Rosen 1 collaboration

Bradley F Boeve 1 collaboration

Penny Dacks 1 collaboration

Stephanie Cosentino 1 collaboration

Sharon Abrahams 1 collaboration

Neil Shneider 1 collaboration

Paul Lingor 1 collaboration

Jeremy Shefner 1 collaboration

Peter M Andersen 1 collaboration

Ammar Al-Chalabi 1 collaboration

Martin R Turner 1 collaboration