M A Bakowski

Affiliations

Calibr, a division of The Scripps Research Institute; La Jolla, CA, 92037, USA.

Publications (15)

Boron-Pleuromutilins as Anti- Wolbachia Agents with Potential for Treatment of Onchocerciasis and Lymphatic Filariasis.

Journal of medicinal chemistry

Avec: Robert T Jacobs , Christopher S Lunde , Yvonne R Freund , Vincent Hernandez , Xianfeng Li , Yi Xia , David S Carter , Pamela W Berry , Jason Halladay , Fernando Rock , Rianna Stefanakis , Eric Easom , Jacob J Plattner , Louise Ford , Kelly L Johnston , Darren A N Cook , Rachel Clare , Andrew Cassidy , Laura Myhill , Hayley Tyrer , Joanne Gamble , Ana F Guimaraes , Andrew Steven , Franziska Lenz , Alexandra Ehrens , Stefan J Frohberger , Marianne Koschel , Achim Hoerauf , Marc P Hübner , Case W McNamara , Malina A Bakowski , Joseph D Turner , Mark J Taylor , Stephen A Ward

Pyridopyrimidinones as a new chemotype of calcium dependent protein kinase 1 (CDPK1) inhibitors for Cryptosporidium.

Molecular and biochemical parasitology

Avec: Elise Waldron-Young , Wissarut Wijitrmektong , Ryan Choi , Grant R Whitman , Matthew A Hulverson , Raheela Charania , Aidan Keelaghan , Li Li , Songpol Srinual , Sameer Nikhar , Case W McNamara , Melissa S Love , Lauren Huerta , Malina A Bakowski , Ming Hu , Wesley C Van Voorhis , Jan R Mead , Gregory D Cuny

Drug Discovery for Cutaneous Leishmaniasis: A Review of Developments in the Past 15 Years.

Microorganisms

Avec: Hannah N Corman , Case W McNamara , Malina A Bakowski

Preclinical characterization of an intravenous coronavirus 3CL protease inhibitor for the potential treatment of COVID19.

Nature communications

Avec: Britton Boras , Rhys M Jones , Brandon J Anson , Dan Arenson , Lisa Aschenbrenner , Malina A Bakowski , Nathan Beutler , Joseph Binder , Emily Chen , Heather Eng , Holly Hammond , Jennifer Hammond , Robert E Haupt , Robert Hoffman , Eugene P Kadar , Rob Kania , Emi Kimoto , Melanie G Kirkpatrick , Lorraine Lanyon , Emma K Lendy , Jonathan R Lillis , James Logue , Suman A Luthra , Chunlong Ma , Stephen W Mason , Marisa E McGrath , Stephen Noell , R Scott Obach , Matthew N O' Brien , Rebecca O'Connor , Kevin Ogilvie , Dafydd Owen , Martin Pettersson , Matthew R Reese , Thomas F Rogers , Romel Rosales , Michelle I Rossulek , Jean G Sathish , Norimitsu Shirai , Claire Steppan , Martyn Ticehurst , Lawrence W Updyke , Stuart Weston , Yuao Zhu , Kris M White , Adolfo García-Sastre , Jun Wang , Arnab K Chatterjee , Andrew D Mesecar , Matthew B Frieman , Annaliesa S Anderson , Charlotte Allerton

Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication.

Cell reports

Avec: Gustavo Garcia , Arun Sharma , Arunachalam Ramaiah , Chandani Sen , Arunima Purkayastha , Donald B Kohn , Mark S Parcells , Sebastian Beck , Heeyoung Kim , Malina A Bakowski , Melanie G Kirkpatrick , Laura Riva , Karen C Wolff , Brandon Han , Constance Yuen , David Ulmert , Prabhat K Purbey , Philip Scumpia , Nathan Beutler , Thomas F Rogers , Arnab K Chatterjee , Gülsah Gabriel , Ralf Bartenschlager , Brigitte Gomperts , Clive N Svendsen , Ulrich A K Betz , Robert D Damoiseaux , Vaithilingaraja Arumugaswami

Discovery of CMX990: A Potent SARS-CoV-2 3CL Protease Inhibitor Bearing a Novel Warhead.

Journal of medicinal chemistry

Avec: N G R Dayan Elshan , Karen C Wolff , Laura Riva , Ashley K Woods , Gennadii Grabovyi , Katy Wilson , James Pedroarena , Sourav Ghorai , Armen Nazarian , Frank Weiss , Yuyin Liu , Wrickban Mazumdar , Lirui Song , Neechi Okwor , Jacqueline Malvin , Malina A Bakowski , Nathan Beutler , Melanie G Kirkpatrick , Amal Gebara-Lamb , Edward Huang , Vân T B Nguyen-Tran , Victor Chi , Shuangwei Li , Thomas F Rogers , Case W McNamara , Anil Kumar Gupta , Alireza Rahimi , Jian Jeffrey Chen , Sean B Joseph , Peter G Schultz , Arnab K Chatterjee

Discovery of short-course antiwolbachial quinazolines for elimination of filarial worm infections.

Science translational medicine

Avec: Malina A Bakowski , Roohollah Kazem Shiroodi , Renhe Liu , Jason Olejniczak , Baiyuan Yang , Kerstin Gagaring , Hui Guo , Pamela M White , Laura Chappell , Alain Debec , Frédéric Landmann , Bettina Dubben , Franziska Lenz , Dominique Struever , Alexandra Ehrens , Stefan J Frohberger , Hanna Sjoberg , Nicolas Pionnier , Emma Murphy , John Archer , Andrew Steven , Valerine C Chunda , Fanny F Fombad , Patrick W Chounna , Abdel J Njouendou , Haelly M Metuge , Bertrand L Ndzeshang , Narcisse V Gandjui , Desmond N Akumtoh , Tayong D B Kwenti , Ashley K Woods , Sean B Joseph , Mitchell V Hull , Wen Xiong , Kelli L Kuhen , Mark J Taylor , Samuel Wanji , Joseph D Turner , Marc P Hübner , Achim Hoerauf , Arnab K Chatterjee , Jason Roland , Matt S Tremblay , Peter G Schultz , William Sullivan , Xin-Jie Chu , H Michael Petrassi , Case W McNamara

Drug repurposing screens identify chemical entities for the development of COVID-19 interventions.

Nature communications

Avec: Malina A Bakowski , Nathan Beutler , Karen C Wolff , Melanie G Kirkpatrick , Emily Chen , Tu-Trinh H Nguyen , Laura Riva , Namir Shaabani , Mara Parren , James Ricketts , Anil K Gupta , Kastin Pan , Peiting Kuo , MacKenzie Fuller , Elijah Garcia , John R Teijaro , Linlin Yang , Debashis Sahoo , Victor Chi , Edward Huang , Natalia Vargas , Amanda J Roberts , Soumita Das , Pradipta Ghosh , Ashley K Woods , Sean B Joseph , Mitchell V Hull , Peter G Schultz , Dennis R Burton , Arnab K Chatterjee , Case W McNamara , Thomas F Rogers

Discovery of a Novel Inhibitor of Coronavirus 3CL Protease for the Potential Treatment of COVID-19.

bioRxiv : the preprint server for biology

Avec: Britton Boras , Rhys M Jones , Brandon J Anson , Dan Arenson , Lisa Aschenbrenner , Malina A Bakowski , Nathan Beutler , Joseph Binder , Emily Chen , Heather Eng , Holly Hammond , Jennifer Hammond , Robert E Haupt , Robert Hoffman , Eugene P Kadar , Rob Kania , Emi Kimoto , Melanie G Kirkpatrick , Lorraine Lanyon , Emma K Lendy , Jonathan R Lillis , James Logue , Suman A Luthra , Chunlong Ma , Stephen W Mason , Marisa E McGrath , Stephen Noell , R Scott Obach , Matthew N O'Brien , Rebecca O'Connor , Kevin Ogilvie , Dafydd Owen , Martin Pettersson , Matthew R Reese , Thomas F Rogers , Michelle I Rossulek , Jean G Sathish , Norimitsu Shirai , Claire Steppan , Martyn Ticehurst , Lawrence W Updyke , Stuart Weston , Yuao Zhu , Jun Wang , Arnab K Chatterjee , Andrew D Mesecar , Matthew B Frieman , Annaliesa S Anderson , Charlotte Allerton

Targeted protein S-nitrosylation of ACE2 inhibits SARS-CoV-2 infection.

Nature chemical biology

Avec: Chang-Ki Oh , Tomohiro Nakamura , Nathan Beutler , Xu Zhang , Juan Piña-Crespo , Maria Talantova , Swagata Ghatak , Dorit Trudler , Lauren N Carnevale , Scott R McKercher , Malina A Bakowski , Jolene K Diedrich , Amanda J Roberts , Ashley K Woods , Victor Chi , Anil K Gupta , Mia A Rosenfeld , Fiona L Kearns , Lorenzo Casalino , Namir Shaabani , Hejun Liu , Ian A Wilson , Rommie E Amaro , Dennis R Burton , John R Yates , Cyrus Becker , Thomas F Rogers , Arnab K Chatterjee , Stuart A Lipton

Advances in Antiwolbachial Drug Discovery for Treatment of Parasitic Filarial Worm Infections.

Tropical medicine and infectious disease

Avec: Malina A Bakowski , Case W McNamara

Discovery of Kirromycins with Anti- Wolbachia Activity from Streptomyces sp. CB00686.

ACS chemical biology

Avec: Zhengren Xu , Shi-Ming Fang , Malina A Bakowski , Mostafa E Rateb , Dong Yang , Xiangcheng Zhu , Yong Huang , Li-Xing Zhao , Yi Jiang , Yanwen Duan , Mitchell V Hull , Case W McNamara , Ben Shen

A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in

bioRxiv : the preprint server for biology

Avec: S P Maher , M A Bakowski , A Vantaux , E L Flannery , C Andolina , M Gupta , Y Antonova-Koch , M Argomaniz , M Cabrera-Mora , B Campo , A T Chao , A K Chatterjee , W T Cheng , C A Cooper , K Cottier , M R Galinski , A Harupa-Chung , H Ji , S B Joseph , T Lenz , S Lonardi , J Matheson , S A Mikolajczak , V Padin-Irizarry , K Pan , J Peneau , J Prudhomme , C Roesch , A A Ruberto , S S Sabnis , C L Saney , J Sattabongkot , S Sereshki , S Suriyakan , T Moeller , R Ubalee , Y Wang , P Wasisakun , J Yin , C W McNamara , C J Joyner , F Nosten , B Witkowski , K G Le Roch , D E Kyle

Short-course quinazoline drug treatments are effective in the Litomosoides sigmodontis and Brugia pahangi jird models.

International journal for parasitology. Drugs and drug resistance

Avec: Marc P Hübner , Emma Gunderson , Ian Vogel , Christina A Bulman , K C Lim , Marianne Koschel , Alexandra Ehrens , Stefan J Frohberger , Martina Fendler , Nancy Tricoche , Denis Voronin , Andrew Steven , Victor Chi , Malina A Bakowski , Ashley K Woods , H Michael Petrassi , Case W McNamara , Brenda Beerntsen , Laura Chappell , William Sullivan , Mark J Taylor , Joseph D Turner , Achim Hoerauf , Sara Lustigman , Judy A Sakanari

Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection.

bioRxiv : the preprint server for biology

Réseau de co-auteurs

Malina A Bakowski 14 collaborations

Case W McNamara 9 collaborations

Arnab K Chatterjee 8 collaborations

Nathan Beutler 7 collaborations

Thomas F Rogers 7 collaborations

Ashley K Woods 6 collaborations

Melanie G Kirkpatrick 5 collaborations

Victor Chi 5 collaborations

Andrew Steven 3 collaborations

Alexandra Ehrens 3 collaborations

Stefan J Frohberger 3 collaborations

Achim Hoerauf 3 collaborations

Marc P Hübner 3 collaborations

Joseph D Turner 3 collaborations

Mark J Taylor 3 collaborations

Emily Chen 3 collaborations

Laura Riva 3 collaborations

Karen C Wolff 3 collaborations

Sean B Joseph 3 collaborations

Peter G Schultz 3 collaborations

Mitchell V Hull 3 collaborations

Namir Shaabani 3 collaborations

Anil K Gupta 3 collaborations

Amanda J Roberts 3 collaborations

Dennis R Burton 3 collaborations

Franziska Lenz 2 collaborations

Marianne Koschel 2 collaborations

Britton Boras 2 collaborations

Rhys M Jones 2 collaborations

Brandon J Anson 2 collaborations

Dan Arenson 2 collaborations

Lisa Aschenbrenner 2 collaborations

Joseph Binder 2 collaborations

Heather Eng 2 collaborations

Holly Hammond 2 collaborations

Jennifer Hammond 2 collaborations

Robert E Haupt 2 collaborations

Robert Hoffman 2 collaborations

Eugene P Kadar 2 collaborations

Rob Kania 2 collaborations

Emi Kimoto 2 collaborations

Lorraine Lanyon 2 collaborations

Emma K Lendy 2 collaborations

Jonathan R Lillis 2 collaborations

James Logue 2 collaborations

Suman A Luthra 2 collaborations

Chunlong Ma 2 collaborations

Stephen W Mason 2 collaborations

Marisa E McGrath 2 collaborations

Stephen Noell 2 collaborations

R Scott Obach 2 collaborations

Rebecca O'Connor 2 collaborations

Kevin Ogilvie 2 collaborations

Dafydd Owen 2 collaborations

Martin Pettersson 2 collaborations

Matthew R Reese 2 collaborations

Michelle I Rossulek 2 collaborations

Jean G Sathish 2 collaborations

Norimitsu Shirai 2 collaborations

Claire Steppan 2 collaborations

Martyn Ticehurst 2 collaborations

Lawrence W Updyke 2 collaborations

Stuart Weston 2 collaborations

Yuao Zhu 2 collaborations

Jun Wang 2 collaborations

Andrew D Mesecar 2 collaborations

Matthew B Frieman 2 collaborations

Annaliesa S Anderson 2 collaborations

Charlotte Allerton 2 collaborations

Edward Huang 2 collaborations

Laura Chappell 2 collaborations

William Sullivan 2 collaborations

H Michael Petrassi 2 collaborations

Chang-Ki Oh 2 collaborations

Tomohiro Nakamura 2 collaborations

Xu Zhang 2 collaborations

Juan Piña-Crespo 2 collaborations

Maria Talantova 2 collaborations

Swagata Ghatak 2 collaborations

Dorit Trudler 2 collaborations

Lauren N Carnevale 2 collaborations

Scott R McKercher 2 collaborations

Jolene K Diedrich 2 collaborations

Mia A Rosenfeld 2 collaborations

Fiona L Kearns 2 collaborations

Lorenzo Casalino 2 collaborations

Hejun Liu 2 collaborations

Ian A Wilson 2 collaborations

Rommie E Amaro 2 collaborations

John R Yates 2 collaborations

Cyrus Becker 2 collaborations

Stuart A Lipton 2 collaborations

Robert T Jacobs 1 collaboration

Christopher S Lunde 1 collaboration

Yvonne R Freund 1 collaboration

Vincent Hernandez 1 collaboration

Xianfeng Li 1 collaboration

Yi Xia 1 collaboration

David S Carter 1 collaboration

Pamela W Berry 1 collaboration

Jason Halladay 1 collaboration

Fernando Rock 1 collaboration

Rianna Stefanakis 1 collaboration

Eric Easom 1 collaboration

Jacob J Plattner 1 collaboration

Louise Ford 1 collaboration

Kelly L Johnston 1 collaboration

Darren A N Cook 1 collaboration

Rachel Clare 1 collaboration

Andrew Cassidy 1 collaboration

Laura Myhill 1 collaboration

Hayley Tyrer 1 collaboration

Joanne Gamble 1 collaboration

Ana F Guimaraes 1 collaboration

Stephen A Ward 1 collaboration

Elise Waldron-Young 1 collaboration

Wissarut Wijitrmektong 1 collaboration

Ryan Choi 1 collaboration

Grant R Whitman 1 collaboration

Matthew A Hulverson 1 collaboration

Raheela Charania 1 collaboration

Aidan Keelaghan 1 collaboration

Li Li 1 collaboration

Songpol Srinual 1 collaboration

Sameer Nikhar 1 collaboration

Melissa S Love 1 collaboration

Lauren Huerta 1 collaboration

Ming Hu 1 collaboration

Wesley C Van Voorhis 1 collaboration

Jan R Mead 1 collaboration

Gregory D Cuny 1 collaboration

Hannah N Corman 1 collaboration

Matthew N O' Brien 1 collaboration

Romel Rosales 1 collaboration

Kris M White 1 collaboration

Adolfo García-Sastre 1 collaboration

Gustavo Garcia 1 collaboration

Arun Sharma 1 collaboration

Arunachalam Ramaiah 1 collaboration

Chandani Sen 1 collaboration

Arunima Purkayastha 1 collaboration

Donald B Kohn 1 collaboration

Mark S Parcells 1 collaboration

Sebastian Beck 1 collaboration

Heeyoung Kim 1 collaboration

Brandon Han 1 collaboration

Constance Yuen 1 collaboration

David Ulmert 1 collaboration

Prabhat K Purbey 1 collaboration

Philip Scumpia 1 collaboration

Gülsah Gabriel 1 collaboration

Ralf Bartenschlager 1 collaboration

Brigitte Gomperts 1 collaboration

Clive N Svendsen 1 collaboration

Ulrich A K Betz 1 collaboration

Robert D Damoiseaux 1 collaboration

Vaithilingaraja Arumugaswami 1 collaboration

N G R Dayan Elshan 1 collaboration

Gennadii Grabovyi 1 collaboration

Katy Wilson 1 collaboration

James Pedroarena 1 collaboration

Sourav Ghorai 1 collaboration

Armen Nazarian 1 collaboration

Frank Weiss 1 collaboration

Yuyin Liu 1 collaboration

Wrickban Mazumdar 1 collaboration

Lirui Song 1 collaboration

Neechi Okwor 1 collaboration

Jacqueline Malvin 1 collaboration

Amal Gebara-Lamb 1 collaboration

Vân T B Nguyen-Tran 1 collaboration

Shuangwei Li 1 collaboration

Anil Kumar Gupta 1 collaboration

Alireza Rahimi 1 collaboration

Jian Jeffrey Chen 1 collaboration

Roohollah Kazem Shiroodi 1 collaboration

Renhe Liu 1 collaboration

Jason Olejniczak 1 collaboration

Baiyuan Yang 1 collaboration

Kerstin Gagaring 1 collaboration

Hui Guo 1 collaboration

Pamela M White 1 collaboration

Alain Debec 1 collaboration

Frédéric Landmann 1 collaboration

Bettina Dubben 1 collaboration

Dominique Struever 1 collaboration

Hanna Sjoberg 1 collaboration

Nicolas Pionnier 1 collaboration

Emma Murphy 1 collaboration

John Archer 1 collaboration

Valerine C Chunda 1 collaboration

Fanny F Fombad 1 collaboration

Patrick W Chounna 1 collaboration

Abdel J Njouendou 1 collaboration

Haelly M Metuge 1 collaboration

Bertrand L Ndzeshang 1 collaboration

Narcisse V Gandjui 1 collaboration

Desmond N Akumtoh 1 collaboration

Tayong D B Kwenti 1 collaboration

Wen Xiong 1 collaboration

Kelli L Kuhen 1 collaboration

Samuel Wanji 1 collaboration

Jason Roland 1 collaboration

Matt S Tremblay 1 collaboration

Xin-Jie Chu 1 collaboration

Tu-Trinh H Nguyen 1 collaboration

Mara Parren 1 collaboration

James Ricketts 1 collaboration

Kastin Pan 1 collaboration

Peiting Kuo 1 collaboration

MacKenzie Fuller 1 collaboration

Elijah Garcia 1 collaboration

John R Teijaro 1 collaboration

Linlin Yang 1 collaboration

Debashis Sahoo 1 collaboration

Natalia Vargas 1 collaboration

Soumita Das 1 collaboration

Pradipta Ghosh 1 collaboration

Matthew N O'Brien 1 collaboration

Zhengren Xu 1 collaboration

Shi-Ming Fang 1 collaboration

Mostafa E Rateb 1 collaboration

Dong Yang 1 collaboration

Xiangcheng Zhu 1 collaboration

Yong Huang 1 collaboration

Li-Xing Zhao 1 collaboration

Yi Jiang 1 collaboration

Yanwen Duan 1 collaboration

Ben Shen 1 collaboration

S P Maher 1 collaboration

A Vantaux 1 collaboration

E L Flannery 1 collaboration

C Andolina 1 collaboration

M Gupta 1 collaboration

Y Antonova-Koch 1 collaboration

M Argomaniz 1 collaboration

M Cabrera-Mora 1 collaboration

B Campo 1 collaboration

A T Chao 1 collaboration

A K Chatterjee 1 collaboration

W T Cheng 1 collaboration

C A Cooper 1 collaboration

K Cottier 1 collaboration

M R Galinski 1 collaboration

A Harupa-Chung 1 collaboration

H Ji 1 collaboration

S B Joseph 1 collaboration

T Lenz 1 collaboration

S Lonardi 1 collaboration

J Matheson 1 collaboration

S A Mikolajczak 1 collaboration

V Padin-Irizarry 1 collaboration

K Pan 1 collaboration

J Peneau 1 collaboration

J Prudhomme 1 collaboration

C Roesch 1 collaboration

A A Ruberto 1 collaboration

S S Sabnis 1 collaboration

C L Saney 1 collaboration

J Sattabongkot 1 collaboration

S Sereshki 1 collaboration

S Suriyakan 1 collaboration

T Moeller 1 collaboration

R Ubalee 1 collaboration

Y Wang 1 collaboration

P Wasisakun 1 collaboration

J Yin 1 collaboration

C W McNamara 1 collaboration

C J Joyner 1 collaboration

F Nosten 1 collaboration

B Witkowski 1 collaboration

K G Le Roch 1 collaboration

D E Kyle 1 collaboration

Emma Gunderson 1 collaboration

Ian Vogel 1 collaboration

Christina A Bulman 1 collaboration

K C Lim 1 collaboration

Martina Fendler 1 collaboration

Nancy Tricoche 1 collaboration

Denis Voronin 1 collaboration

Brenda Beerntsen 1 collaboration

Sara Lustigman 1 collaboration

Judy A Sakanari 1 collaboration