M Shackleton

Affiliations

The Alfred Hospital, Melbourne.

Publications (27)

Macroinvertebrate Responses to Conductivity in Different Bioregions of Victoria, Australia.

Environmental toxicology and chemistry

Avec: Michael Shackleton , Aleicia Holland , Leigh Stitz , Paul McInerney

Parity reduces mammary repopulating activity but does not affect mammary stem cells defined as CD24 + CD29/CD49fhi in mice.

Breast cancer research and treatment

Avec: Genevieve V Dall , Jessica Vieusseux , Yashar Seyed-Razavi , Nathan Godde , Mandy Ludford-Menting , Sarah M Russell , Alan Ashworth , Robin L Anderson , Gail P Risbridger , Mark Shackleton , Kara L Britt

Reduced melanoma referrals during COVID-19 lockdown.

Australian journal of general practice

Avec: William Berry , Katrina Tan , Andrew Haydon , Mark Shackleton , Victoria J Mar

Computational repurposing of oncology drugs through off-target drug binding interactions from pharmacological databases.

Clinical and translational medicine

Avec: Imogen R Walpole , Farzana Y Zaman , Peinan Zhao , Vikki M Marshall , Frank P Lin , David M Thomas , Mark Shackleton , Albert A Antolin , Malaka Ameratunga

A capability framework to inform the fundamental requirements for clinical trial unit development, growth and long term success in outer metropolitan and rural areas.

Contemporary clinical trials communications

Avec: Anne Woollett , Jhodie Duncan , Mark Voskoboynik , Mark Shackleton , Michael Dooley , Robert Blum , Narelle McPhee , Tricia Wright , Zee Wan Wong , Jacqueline Dixon , Stephen M Jane

Immune Regulation and Immune Therapy in Melanoma: Review with Emphasis on CD155 Signalling.

Cancers

Avec: Li-Ying Wu , Su-Ho Park , Haakan Jakobsson , Mark Shackleton , Andreas Möller

Predictive Impact of Tumor Mutational Burden on Real-World Outcomes of First-Line Immune Checkpoint Inhibition in Metastatic Melanoma.

JCO precision oncology

Avec: Miles C Andrews , Gerald Li , Ryon P Graf , Virginia A Fisher , Jerry Mitchell , Ali Aboosaiedi , Harriet O'Rourke , Mark Shackleton , Mahesh Iddawela , Geoffrey R Oxnard , Richard S P Huang

Somatic Hypermutation of the

Molecular cancer research : MCR

Avec: Xiaomeng Zhang , Jian Zhong Tang , Ismael A Vergara , Youfang Zhang , Pacman Szeto , Lie Yang , Christopher Mintoff , Andrew Colebatch , Lachlan McIntosh , Katrina A Mitchell , Evangeline Shaw , Helen Rizos , Georgina V Long , Nicholas Hayward , Grant A McArthur , Anthony T Papenfuss , Kieran F Harvey , Mark Shackleton

Prediction and monitoring of relapse in stage III melanoma using circulating tumor DNA.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: L Tan , S Sandhu , R J Lee , J Li , J Callahan , S Ftouni , N Dhomen , P Middlehurst , A Wallace , J Raleigh , A Hatzimihalis , M A Henderson , M Shackleton , A Haydon , V Mar , D E Gyorki , D Oudit , M A Dawson , R J Hicks , P Lorigan , G A McArthur , R Marais , S Q Wong , S-J Dawson

Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling.

Nature communications

Avec: Ismael A Vergara , Christopher P Mintoff , Shahneen Sandhu , Lachlan McIntosh , Richard J Young , Stephen Q Wong , Andrew Colebatch , Daniel L Cameron , Julia Lai Kwon , Rory Wolfe , Angela Peng , Jason Ellul , Xuelin Dou , Clare Fedele , Samantha Boyle , Gisela Mir Arnau , Jeanette Raleigh , Athena Hatzimihalis , Pacman Szeto , Jennifer Mooi , Daniel S Widmer , Phil F Cheng , Valerie Amann , Reinhard Dummer , Nicholas Hayward , James Wilmott , Richard A Scolyer , Raymond J Cho , David Bowtell , Heather Thorne , Kathryn Alsop , Stephen Cordner , Noel Woodford , Jodie Leditschke , Patricia O'Brien , Sarah-Jane Dawson , Grant A McArthur , Graham J Mann , Mitchell P Levesque , Anthony T Papenfuss , Mark Shackleton

Yield of baseline imaging for distant metastases in high-risk primary melanoma.

Journal of surgical oncology

Avec: Mabel K Yan , Nikki R Adler , Yan Pan , Alexander Chamberlain , John Kelly , Kenneth Yap , Mark Voskoboynik , Andrew Haydon , Mark Shackleton , Victoria J Mar

Developing an Australian Melanoma Clinical Outcomes Registry (MelCOR): a protocol paper.

BMJ open

Avec: Dale Jobson , Benjamin Roffey , Renee Best , Alison Button-Sloan , Danica Cossio , Sue Evans , Catherine Shang , Julie Moore , Christopher Arnold , Graham Mann , Mark Shackleton , H Peter Soyer , Rachel L Morton , John Zalcberg , Victoria Mar

UHRF1/UBE2L6/UBR4-mediated ubiquitination regulates EZH2 abundance and thereby melanocytic differentiation phenotypes in melanoma.

Oncogene

Avec: Gamze Kuser-Abali , Youfang Zhang , Pacman Szeto , Peinan Zhao , Samar Masoumi-Moghaddam , Clare G Fedele , Isobel Leece , Cheng Huang , Jen G Cheung , Malaka Ameratunga , Fumihito Noguchi , Miles C Andrews , Nicholas C Wong , Ralf B Schittenhelm , Mark Shackleton

Stereotactic Radiation Therapy Combined With Immunotherapy Against Metastatic Melanoma: Long-Term Results of a Phase 1 Clinical Trial.

International journal of radiation oncology, biology, physics

Avec: Gishan Ratnayake , Simone Reinwald , Mark Shackleton , Maggie Moore , Mark Voskoboynik , Jeremy Ruben , Menno C van Zelm , Di Yu , Rachel Ward , Robin Smith , Andrew Haydon , Sashendra Senthi

Bevacizumab as a steroid-sparing agent during immunotherapy for melanoma brain metastases: A case series.

Health science reports

Avec: Patricia D Banks , Arian Lasocki , Peter K H Lau , Shahneen Sandhu , Grant McArthur , Mark Shackleton

Cancer Diagnoses Following Abnormal Noninvasive Prenatal Testing: A Case Series, Literature Review, and Proposed Management Model.

JCO precision oncology

Avec: Eryn Dow , Alison Freimund , Kortnye Smith , Rodney J Hicks , Peter Jurcevic , Mark Shackleton , Paul A James , Andrew Fellowes , Martin B Delatycki , Susan Fawcett , Nicola Flowers , Mark D Pertile , George McGillivray , Linda Mileshkin

An update on adjuvant systemic therapies in melanoma.

Melanoma management

Avec: Evangeline Samuel , Maggie Moore , Mark Voskoboynik , Mark Shackleton , Andrew Haydon

Feasibility and Acceptability of

Journal of clinical medicine

Avec: Fiona A Lynch , Lynda Katona , Michael Jefford , Allan Ben Smith , Joanne Shaw , Haryana M Dhillon , Steve Ellen , Jo Phipps-Nelson , Julia Lai-Kwon , Donna Milne , Lahiru Russell , Victoria Dax , Justine Diggens , Holly Kent , Alison Button-Sloan , Jane Elliott , Mark Shackleton , Hayley Burridge , Maria Ftanou

Connectivity, not short-range endemism, characterises the groundwater biota of a northern Australian karst system.

The Science of the total environment

Avec: Stefanie Oberprieler , Gavin Rees , Daryl Nielsen , Michael Shackleton , Garth Watson , Lisa Chandler , Jenny Davis

Design, optimisation and standardisation of a high-dimensional spectral flow cytometry workflow assessing T-cell immunophenotype in patients with melanoma.

Clinical & translational immunology

Avec: Jack M Edwards , Miles C Andrews , Hayley Burridge , Robin Smith , Carole Owens , Mark Edinger , Katherine Pilkington , Juliette Desfrancois , Mark Shackleton , Sashendra Senthi , Menno C van Zelm

Globe Salvage and Vision Preservation by Neoadjuvant Darovasertib and Crizotinib in Uveal Melanoma.

Ophthalmology. Retina

Avec: Alison Hiong , Roderick O'Day , Lotte S Fog , Daniel McKay , John McKenzie , Malaka Ameratunga , Anthony M Joshua , Mark Shackleton

Immune-related adverse events are associated with therapeutic efficacy of immunotherapy in patients with melanoma brain metastases.

Melanoma research

Avec: Cecilia W Huo , Indika Gunadasa , Panagiota Gkolia , Mark Shackleton , Martin Hunn

Metastatic melanoma presenting as intravenous tumour thrombus.

Journal of medical imaging and radiation oncology

Avec: Jennifer Nguyen , Warren Clements , Catriona McLean , Andrew Haydon , Maggie Moore , Kenneth Sk Yap , Victoria Mar , Mark Shackleton

The Hippo pathway oncoprotein YAP promotes melanoma cell invasion and spontaneous metastasis.

Oncogene

Avec: Xiaomeng Zhang , Lie Yang , Pacman Szeto , Gamze Kuser Abali , Youfang Zhang , Aishwarya Kulkarni , Kaushalya Amarasinghe , Jason Li , Ismael A Vergara , Ramyar Molania , Anthony T Papenfuss , Catriona McLean , Mark Shackleton , Kieran F Harvey

Melanoma recurrence patterns and management after adjuvant targeted therapy: a multicentre analysis.

British journal of cancer

Avec: Prachi Bhave , Lalit Pallan , Georgina V Long , Alexander M Menzies , Victoria Atkinson , Justine V Cohen , Ryan J Sullivan , Vanna Chiarion-Sileni , Marta Nyakas , Katharina Kahler , Axel Hauschild , Ruth Plummer , Claudia Trojaniello , Paolo A Ascierto , Lisa Zimmer , Dirk Schadendorf , Clara Allayous , Celeste Lebbe , Andrea Maurichi , Mario Santinami , Severine Roy , Caroline Robert , Thierry Lesimple , Sapna Patel , Judith M Versluis , Christian U Blank , Adnan Khattak , Andre Van der Westhuizen , Matteo S Carlino , Mark Shackleton , Andrew Haydon

Implementation of patient-reported outcome measures and patient-reported experience measures in melanoma clinical quality registries: a systematic review.

BMJ open

Avec: Zachary Blood , Anh Tran , Lauren Caleo , Robyn Saw , Mbathio Dieng , Mark Shackleton , H Peter Soyer , Chris Arnold , Graham J Mann , Rachael L Morton

Phase I/II trial of concurrent extracranial palliative radiation therapy with Dabrafenib and Trametinib in metastatic BRAF V600E/K mutation-positive cutaneous Melanoma.

Clinical and translational radiation oncology

Avec: Wei Wang , Jessica Louise Smith , Matteo Salvatore Carlino , Bryan Burmeister , Mark Blayne Pinkham , Gerald Blaise Fogarty , David Robert Harry Christie , Vanessa Estall , Mark Shackleton , Arthur Clements , Rory Wolfe , Le Thi Phuong Thao , Elizabeth Jane Paton , Victoria Steel , Narelle Catherine Williams

Réseau de co-auteurs

Mark Shackleton 24 collaborations

Andrew Haydon 6 collaborations

Mark Voskoboynik 4 collaborations

Pacman Szeto 4 collaborations

Malaka Ameratunga 3 collaborations

Miles C Andrews 3 collaborations

Ismael A Vergara 3 collaborations

Youfang Zhang 3 collaborations

Anthony T Papenfuss 3 collaborations

Maggie Moore 3 collaborations

Michael Shackleton 2 collaborations

Victoria J Mar 2 collaborations

Peinan Zhao 2 collaborations

Xiaomeng Zhang 2 collaborations

Lie Yang 2 collaborations

Andrew Colebatch 2 collaborations

Lachlan McIntosh 2 collaborations

Georgina V Long 2 collaborations

Nicholas Hayward 2 collaborations

Grant A McArthur 2 collaborations

Kieran F Harvey 2 collaborations

Shahneen Sandhu 2 collaborations

Rory Wolfe 2 collaborations

Graham J Mann 2 collaborations

Alison Button-Sloan 2 collaborations

H Peter Soyer 2 collaborations

Victoria Mar 2 collaborations

Menno C van Zelm 2 collaborations

Robin Smith 2 collaborations

Sashendra Senthi 2 collaborations

Hayley Burridge 2 collaborations

Catriona McLean 2 collaborations

Aleicia Holland 1 collaboration

Leigh Stitz 1 collaboration

Paul McInerney 1 collaboration

Genevieve V Dall 1 collaboration

Jessica Vieusseux 1 collaboration

Yashar Seyed-Razavi 1 collaboration

Nathan Godde 1 collaboration

Mandy Ludford-Menting 1 collaboration

Sarah M Russell 1 collaboration

Alan Ashworth 1 collaboration

Robin L Anderson 1 collaboration

Gail P Risbridger 1 collaboration

Kara L Britt 1 collaboration

William Berry 1 collaboration

Katrina Tan 1 collaboration

Imogen R Walpole 1 collaboration

Farzana Y Zaman 1 collaboration

Vikki M Marshall 1 collaboration

Frank P Lin 1 collaboration

David M Thomas 1 collaboration

Albert A Antolin 1 collaboration

Anne Woollett 1 collaboration

Jhodie Duncan 1 collaboration

Michael Dooley 1 collaboration

Robert Blum 1 collaboration

Narelle McPhee 1 collaboration

Tricia Wright 1 collaboration

Zee Wan Wong 1 collaboration

Jacqueline Dixon 1 collaboration

Stephen M Jane 1 collaboration

Li-Ying Wu 1 collaboration

Su-Ho Park 1 collaboration

Haakan Jakobsson 1 collaboration

Andreas Möller 1 collaboration

Gerald Li 1 collaboration

Ryon P Graf 1 collaboration

Virginia A Fisher 1 collaboration

Jerry Mitchell 1 collaboration

Ali Aboosaiedi 1 collaboration

Harriet O'Rourke 1 collaboration

Mahesh Iddawela 1 collaboration

Geoffrey R Oxnard 1 collaboration

Richard S P Huang 1 collaboration

Jian Zhong Tang 1 collaboration

Christopher Mintoff 1 collaboration

Katrina A Mitchell 1 collaboration

Evangeline Shaw 1 collaboration

Helen Rizos 1 collaboration

L Tan 1 collaboration

S Sandhu 1 collaboration

R J Lee 1 collaboration

J Li 1 collaboration

J Callahan 1 collaboration

S Ftouni 1 collaboration

N Dhomen 1 collaboration

P Middlehurst 1 collaboration

A Wallace 1 collaboration

J Raleigh 1 collaboration

A Hatzimihalis 1 collaboration

M A Henderson 1 collaboration

A Haydon 1 collaboration

V Mar 1 collaboration

D E Gyorki 1 collaboration

D Oudit 1 collaboration

M A Dawson 1 collaboration

R J Hicks 1 collaboration

P Lorigan 1 collaboration

G A McArthur 1 collaboration

R Marais 1 collaboration

S Q Wong 1 collaboration

S-J Dawson 1 collaboration

Christopher P Mintoff 1 collaboration

Richard J Young 1 collaboration

Stephen Q Wong 1 collaboration

Daniel L Cameron 1 collaboration

Julia Lai Kwon 1 collaboration

Angela Peng 1 collaboration

Jason Ellul 1 collaboration

Xuelin Dou 1 collaboration

Clare Fedele 1 collaboration

Samantha Boyle 1 collaboration

Gisela Mir Arnau 1 collaboration

Jeanette Raleigh 1 collaboration

Athena Hatzimihalis 1 collaboration

Jennifer Mooi 1 collaboration

Daniel S Widmer 1 collaboration

Phil F Cheng 1 collaboration

Valerie Amann 1 collaboration

Reinhard Dummer 1 collaboration

James Wilmott 1 collaboration

Richard A Scolyer 1 collaboration

Raymond J Cho 1 collaboration

David Bowtell 1 collaboration

Heather Thorne 1 collaboration

Kathryn Alsop 1 collaboration

Stephen Cordner 1 collaboration

Noel Woodford 1 collaboration

Jodie Leditschke 1 collaboration

Patricia O'Brien 1 collaboration

Sarah-Jane Dawson 1 collaboration

Mitchell P Levesque 1 collaboration

Mabel K Yan 1 collaboration

Nikki R Adler 1 collaboration

Yan Pan 1 collaboration

Alexander Chamberlain 1 collaboration

John Kelly 1 collaboration

Kenneth Yap 1 collaboration

Dale Jobson 1 collaboration

Benjamin Roffey 1 collaboration

Renee Best 1 collaboration

Danica Cossio 1 collaboration

Sue Evans 1 collaboration

Catherine Shang 1 collaboration

Julie Moore 1 collaboration

Christopher Arnold 1 collaboration

Graham Mann 1 collaboration

Rachel L Morton 1 collaboration

John Zalcberg 1 collaboration

Gamze Kuser-Abali 1 collaboration

Samar Masoumi-Moghaddam 1 collaboration

Clare G Fedele 1 collaboration

Isobel Leece 1 collaboration

Cheng Huang 1 collaboration

Jen G Cheung 1 collaboration

Fumihito Noguchi 1 collaboration

Nicholas C Wong 1 collaboration

Ralf B Schittenhelm 1 collaboration

Gishan Ratnayake 1 collaboration

Simone Reinwald 1 collaboration

Jeremy Ruben 1 collaboration

Di Yu 1 collaboration

Rachel Ward 1 collaboration

Patricia D Banks 1 collaboration

Arian Lasocki 1 collaboration

Peter K H Lau 1 collaboration

Grant McArthur 1 collaboration

Eryn Dow 1 collaboration

Alison Freimund 1 collaboration

Kortnye Smith 1 collaboration

Rodney J Hicks 1 collaboration

Peter Jurcevic 1 collaboration

Paul A James 1 collaboration

Andrew Fellowes 1 collaboration

Martin B Delatycki 1 collaboration

Susan Fawcett 1 collaboration

Nicola Flowers 1 collaboration

Mark D Pertile 1 collaboration

George McGillivray 1 collaboration

Linda Mileshkin 1 collaboration

Evangeline Samuel 1 collaboration

Fiona A Lynch 1 collaboration

Lynda Katona 1 collaboration

Michael Jefford 1 collaboration

Allan Ben Smith 1 collaboration

Joanne Shaw 1 collaboration

Haryana M Dhillon 1 collaboration

Steve Ellen 1 collaboration

Jo Phipps-Nelson 1 collaboration

Julia Lai-Kwon 1 collaboration

Donna Milne 1 collaboration

Lahiru Russell 1 collaboration

Victoria Dax 1 collaboration

Justine Diggens 1 collaboration

Holly Kent 1 collaboration

Jane Elliott 1 collaboration

Maria Ftanou 1 collaboration

Stefanie Oberprieler 1 collaboration

Gavin Rees 1 collaboration

Daryl Nielsen 1 collaboration

Garth Watson 1 collaboration

Lisa Chandler 1 collaboration

Jenny Davis 1 collaboration

Jack M Edwards 1 collaboration

Carole Owens 1 collaboration

Mark Edinger 1 collaboration

Katherine Pilkington 1 collaboration

Juliette Desfrancois 1 collaboration

Alison Hiong 1 collaboration

Roderick O'Day 1 collaboration

Lotte S Fog 1 collaboration

Daniel McKay 1 collaboration

John McKenzie 1 collaboration

Anthony M Joshua 1 collaboration

Cecilia W Huo 1 collaboration

Indika Gunadasa 1 collaboration

Panagiota Gkolia 1 collaboration

Martin Hunn 1 collaboration

Jennifer Nguyen 1 collaboration

Warren Clements 1 collaboration

Kenneth Sk Yap 1 collaboration

Gamze Kuser Abali 1 collaboration

Aishwarya Kulkarni 1 collaboration

Kaushalya Amarasinghe 1 collaboration

Jason Li 1 collaboration

Ramyar Molania 1 collaboration

Prachi Bhave 1 collaboration

Lalit Pallan 1 collaboration

Alexander M Menzies 1 collaboration

Victoria Atkinson 1 collaboration

Justine V Cohen 1 collaboration

Ryan J Sullivan 1 collaboration

Vanna Chiarion-Sileni 1 collaboration

Marta Nyakas 1 collaboration

Katharina Kahler 1 collaboration

Axel Hauschild 1 collaboration

Ruth Plummer 1 collaboration

Claudia Trojaniello 1 collaboration

Paolo A Ascierto 1 collaboration

Lisa Zimmer 1 collaboration

Dirk Schadendorf 1 collaboration

Clara Allayous 1 collaboration

Celeste Lebbe 1 collaboration

Andrea Maurichi 1 collaboration

Mario Santinami 1 collaboration

Severine Roy 1 collaboration

Caroline Robert 1 collaboration

Thierry Lesimple 1 collaboration

Sapna Patel 1 collaboration

Judith M Versluis 1 collaboration

Christian U Blank 1 collaboration

Adnan Khattak 1 collaboration

Andre Van der Westhuizen 1 collaboration

Matteo S Carlino 1 collaboration

Zachary Blood 1 collaboration

Anh Tran 1 collaboration

Lauren Caleo 1 collaboration

Robyn Saw 1 collaboration

Mbathio Dieng 1 collaboration

Chris Arnold 1 collaboration

Rachael L Morton 1 collaboration

Wei Wang 1 collaboration

Jessica Louise Smith 1 collaboration

Matteo Salvatore Carlino 1 collaboration

Bryan Burmeister 1 collaboration

Mark Blayne Pinkham 1 collaboration

Gerald Blaise Fogarty 1 collaboration

David Robert Harry Christie 1 collaboration

Vanessa Estall 1 collaboration

Arthur Clements 1 collaboration

Le Thi Phuong Thao 1 collaboration

Elizabeth Jane Paton 1 collaboration

Victoria Steel 1 collaboration

Narelle Catherine Williams 1 collaboration